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  • Embargo expired:
    16-May-2019 2:00 PM EDT

Article ID: 712223

Antibiotics, Taken Strategically, Could Actually Help Defeat Antibiotic Resistance

Georgia Institute of Technology

Those same antibiotics driving antibiotic resistance could also help defeat it if used with the right strategy. Making it work would require companion health strategies like staying home from work when carrying resistant bacteria.

Released:
10-May-2019 5:00 AM EDT
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Article ID: 712900

Researchers Pinpoint Why Lymphoma Patients May Become Resistant to Specific Therapy, Identify Strategy to Overcome It

Moffitt Cancer Center

With more targeted therapies being approved each year for cancer, the development of drug resistance to these agents is a growing concern. It has often been assumed that drug resistance is due to the presence or development of additional genetic alterations; however, it is now clear that resistance mechanisms are more complicated. Researchers from Moffitt Cancer Center and Dana-Farber Cancer Institute have discovered a mechanism of drug resistance to Venetoclax®, also known as ABT-199, a BCL-2 targeting drug commonly used to treat chronic lymphocytic leukemia and acute myeloid leukemia. Their findings, published in the journal Cancer Cell, also suggest a possible co-treatment strategy to overcome this resistance.

Released:
15-May-2019 9:50 AM EDT
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  • Embargo expired:
    9-May-2019 9:00 AM EDT

Article ID: 712364

Patient Registries Could Help Control Spread of Antibiotic Bacteria

Johns Hopkins Bloomberg School of Public Health

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health finds that the spread of carbapenem-resistant Enterobacteriaceae (CRE)—bacteria that have high levels of resistance to most antibiotics—could be reduced if only 25 percent of the largest health care facilities in a region used a patient registry, a database that can track which patients are carrying CRE.

Released:
3-May-2019 1:25 PM EDT
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Article ID: 712479

New ‘Jumping’ Superbug Gene Discovered, Resistant to Last-Resort Antibiotic

Cornell University

While sifting through the bacterial genome of salmonella, Cornell University food scientists discovered mcr-9, a new stealthy, jumping gene so diabolical and robust that it resists one of the world’s few last-resort antibiotics.

Released:
7-May-2019 11:55 AM EDT
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Article ID: 712463

Antibiotics in Wastewater: UB Chemist Investigates a Disturbing Trend

University at Buffalo

Diana Aga's research examines how sewage treatment systems help — or don’t help — to eliminate antimicrobial drugs and their remnants, called residues, from wastewater before it’s discharged into rivers and lakes.

Released:
7-May-2019 9:00 AM EDT
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Article ID: 712113

Unraveling Cannabinoids

Harvard Medical School

Harvard Medical School, MIT receive $9 million to study neurobiology, physiologic effects of cannabinoids

Released:
30-Apr-2019 10:05 AM EDT
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  • Embargo expired:
    30-Apr-2019 10:00 AM EDT

Article ID: 712085

Antibiotics May Treat Endometriosis

Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have found that treating mice with an antibiotic reduces the size of lesions caused by endometriosis. The researchers are planning a clinical trial to test the strategy in women who have the painful condition.

Released:
29-Apr-2019 4:45 PM EDT
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Article ID: 712104

Breaking Open the Gates of Antibiotic Resistance

Thomas Jefferson University

Creating a defect in tRNA molecules could weaken bacteria’s two-pronged defense and help make faster-acting antibiotics.

Released:
30-Apr-2019 8:05 AM EDT

Article ID: 711637

How Penicillin Acts Like TNT for Bacteria

Howard Hughes Medical Institute (HHMI)

Although penicillin was discovered nearly a century ago, scientists are still learning how the drug makes bacterial cells pop like overfilled balloons.

Released:
19-Apr-2019 12:05 PM EDT
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Article ID: 711507

Diet High in Leucine May Fuel Breast Cancer’s Drug Resistance

Beth Israel Deaconess Medical Center

Researchers at the Cancer Center at Beth Israel Deaconess Medical Center revealed an unexpected relationship between levels of the amino acid leucine and the growth of tamoxifen resistance in estrogen-receptor positive breast cancer

Released:
17-Apr-2019 1:05 PM EDT

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