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18-Feb-2019 5:00 AM EST
Released to reporters:
14-Feb-2019 10:05 AM EST


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Article ID: 708031

Drug-Resistant TB Cured with New Approaches in Conflict-Affected Region

Health Sciences at the University of Pittsburgh

A high proportion of multidrug-resistant tuberculosis (TB) cases can be cured in conflict-affected communities with molecular diagnostics, shorter treatment periods and socioeconomic incentives, according to the results of a large, long-term study in the Democratic Republic of Congo.

13-Feb-2019 10:30 AM EST
  • Embargo expired:
    13-Feb-2019 12:05 AM EST

Article ID: 707902

Even as Hospitals Cut Risky Antibiotic Use In-House, Patients Often Go Home with Them

Michigan Medicine - University of Michigan

Even as hospitals try to cut back on prescribing powerful but risky antibiotics called fluoroquinolones, a new study shows that many patients still head home with prescriptions for the drugs -- increasing their risk of everything from "superbug" infections to torn tendons. In fact, the hospitals that are actively trying to reduce inpatient fluoroquinolone use were twice as likely to discharge patients with a new prescription for one of them.

11-Feb-2019 2:05 PM EST
  • Embargo expired:
    7-Feb-2019 2:00 PM EST

Article ID: 707587

Engineered DNA Vaccine Protects Against Emerging Mayaro Virus Infection

Wistar Institute

A novel, synthetic DNA vaccine developed at The Wistar Institute induces protective immunity against Mayaro virus (MAYV), a mosquito-borne infection endemic to South America, that has the potential to become a global emerging viral threat.

5-Feb-2019 4:10 PM EST

Article ID: 707546

Better Assessing Bacterial Sensitivity to Antibiotics Could Change How Drugs Are Prescribed

American Institute of Physics (AIP)

We rely on antibiotics to treat bacterial infections, but the rise of antibiotic-resistant bacteria forces doctors and patients to contend with shifting treatment plans. Furthermore, current laboratory tests to determine what bacteria is causing a particular infection takes days to complete and can be too late for the patient. Mechanical engineers in Korea recently developed a microchip antibiotic testing platform that takes only six to seven hours to determine the appropriate medication.

5-Feb-2019 11:05 AM EST

Article ID: 707440

Step forward for pneumonia vaccine development

University of Adelaide

A vaccine against the biggest bacterial killer on the planet is a step closer to being available with funding secured for preclinical trials.

4-Feb-2019 12:05 AM EST

Article ID: 707392

Microbes hitched to insects provide a rich source of new antibiotics

University of Wisconsin-Madison

. In an exhaustive search of microbes from more than 1,400 insects collected from diverse environments across North and South America, a UW-Madison research team found that insect-borne microbes often outperformed soil bacteria in stopping some of the most common and dangerous antibiotic-resistant pathogens.

1-Feb-2019 10:05 AM EST

Article ID: 707292

Researchers Develop New Approach for Vanquishing Superbugs

Case Western Reserve University

A scientific team from Case Western Reserve University School of Medicine and Cleveland Clinic has developed a new way to identify second-line antibiotics that may be effective in killing germs already resistant to a first-line antibiotic – potentially helping overcome antibiotic resistance. This new research provides an approach clinicians could consult when deciding which antibiotic treatment courses will be most effective for patients.

30-Jan-2019 3:05 PM EST

Article ID: 706488

Molecular Machinery That Makes Potent Antibiotic Revealed After Decades of Research

Rutgers University-New Brunswick

The 3D structure of McbBCD, an enzyme (protein) that makes the potent antibiotic microcin B17 from a smaller protein known as a peptide, as revealed by X-ray crystallography. The red spheres show chemical "cycles" formed by the enzyme that are required for antibacterial activity. Image: Dmitry Ghilarov High Res MEDIA CONTACT Todd Bates 848-932-0550 todd.bates@rutgers.edu YOU MAY ALSO LIKE Scientists Use Bear Saliva to Rapidly Test for Antibiotics Scientists at Rutgers and universities in Russia, Poland and England have solved a nearly 30-year mystery – how the molecular machinery works in an enzyme that makes a potent antibiotic. The findings, which appear in the journal Molecular Cell, provide the tools to design new antibiotics, anticancer drugs and other therapeutics.

17-Jan-2019 11:30 AM EST

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