Anti-vaccine conspiracies fuel divisive political discourse
University of TokyoHeightened use of social media during the coronavirus pandemic brought with it an unprecedented surge in the spread of misinformation.
Heightened use of social media during the coronavirus pandemic brought with it an unprecedented surge in the spread of misinformation.
Stay informed! These are the latest research articles on "Long COVID" from the Coronavirus News Source on Newswise.
RUDN University pharmacists modeled derivative molecules of the antibacterial levofloxacin to find out what biological functions its individual structural fragments - pharmacophores - are responsible for. This is necessary to increase the effectiveness of the drug, as bacteria become increasingly resistant to antibiotics.
Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it’s unknown which of those transporters they use to exit the digestive tract.
New drug inspired by images that captured how bacteria block antibiotic activity
Aunque la cirugía puede ser una opción para hasta el 40% de las personas con epilepsia resistente a los medicamentos, menos del 1% son remitidos a centros de epilepsia cada año. ¿Por qué?
Surgery may be an option for up to 40% of people with drug-resistant epilepsy, but fewer than 1% are referred to epilepsy centers each year. Why?
Scientists have learned more about how drug resistance develops in patients with acute myeloid leukemia and how the process might be slowed, thanks to a study of proteins and other molecular players.
University of Virginia scientists have developed a new approach to machine learning – a form of artificial intelligence – to identify drugs that help minimize harmful scarring after a heart attack or other injuries.
The American Society of Anesthesiologists (ASA) commends the Centers for Medicare & Medicaid Services (CMS) for taking positive steps towards returning balance to the independent dispute resolution (IDR) process of the No Surprises Act (NSA) through a recently proposed rule.
Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have different microenvironments.
The latest research and expertise on the flue can be found in the Influenza channel on Newswise.
Like the rest of the country, Los Angeles County has experienced a dramatic upswing in overdoses from fentanyl, an opiate that is 100 times stronger than heroin.
Protein degraders offer a novel approach to targeting undruggable diseases by hijacking the cell's degradation machinery.
Researchers have identified a receptor protein known as CHRM1 as a key player in prostate cancer cells’ resistance to docetaxel, a commonly used chemotherapy drug to treat advanced cancer that has spread beyond the prostate.
One in three children who suffer from bacterial meningitis live with permanent neurological disabilities due to the infection.
Find the latest research and features on emergency medicine in the Emergency Medicine channel on Newswise.
By taking advantage of mechanisms that allow cancer cells to evade immune attack, UT Southwestern Medical Center researchers have developed a new strategy in animal models that has potential for treating ulcerative colitis.
Antibiotic overuse can lead to antibiotic resistance, a global health problem. But UNC School of Medicine scientists with Duke School of Medicine colleagues have documented another culprit in clinical antibiotic failure: bacterial persister cells.
From a wartime spread of antimicrobial resistant disease in Ukraine, to superbugs in China causing “white lung” pneumonia in children, 2023 brought no shortage of new evidence that antimicrobial resistance (AMR) continues to be a pressing problem globally, and this pattern shows no sign of abating in 2024 unless a radical shift occurs.
Scientists at St. Jude Children’s Research Hospital created analogs of the antibiotic spectinomycin that are significantly more effective against these highly resistant bacteria.
حدد الباحثون والمتعاونون في مايو كلينك بروتينًا تفرزه الخلايا المناعية والذي قد يقوم بدورٍ رئيسيٍ في ظهور مرضالتصلُّب الجانبي الضموري، المعروف أيضًا باسم مرض لو غيريغ. ووجد الفريق أيضًا أن العلاج التعديلي المناعي الذي يقوم بعملية إِحْصار للبروتين يمكنه استعادة الوظيفة الحركية في النماذج قبل السريرية. وتشير النتائج إلى أن البروتين، المعروف باسم أ5 إنتغرين (الذي يُنطق ألفا 5 إنتغرين)، هو مستهدف علاجي محتمل لعلاج مرض التصلُّب الجانبي الضموري.
Los investigadores y colaboradores de Mayo Clinic han identificado una proteína expresada en células inmunitarias que podría desempeñar un rol clave en el desarrollo de la esclerosis lateral amiotrófica (ELA), también conocida como enfermedad de Lou Gehrig. El equipo también descubrió que un tratamiento inmunomodulatorio que bloquea la proteína era capaz de restaurar la función motriz en modelos preclínicos. Los hallazgos indican que la proteína, conocida como integrina α5 (pronunciado integrina alfa 5), es un posible blanco terapéutico para la ELA.
Pesquisadores e colaboradores da Mayo Clinic identificaram uma proteína que é expressa por células imunológicas que pode desempenhar uma função importante no desenvolvimento daesclerose lateral amiotrófica (ELA), também conhecida como doença de Lou Gehrig. A equipe também descobriu que um tratamento imunomodulador que bloqueia a proteína conseguiu restaurar a função motora em modelos pré-clínicos. As descobertas sugerem que a proteína, conhecida como integrina α5 (pronunciada como integrina alfa 5), é um possível alvo terapêutico para ELA.
With the rise in machine learning applications and artificial intelligence, it's no wonder that more and more scientists and researchers are turning to supercomputers. Supercomputers are commonly used for making predictions with advanced modeling and simulations. This can be applied to climate research, weather forecasting, genomic sequencing, space exploration, aviation engineering and more.
Damage to the protein production capacity neutralizes the trypanosome parasite, which causes sleeping sickness. Joint research by Prof.
Researchers from at University of California San Diego, West Health, and the University of Washington have found evidence that the private insurers that sponsor Medicare Part D are artificially inflating the costs of certain generic drugs by overpaying pharmacies.
A study that assesses the effects of hypochlorous acid (HOCI), commonly known as bleach, as it is generated during the immune response of a cell (phagocytosis) when fighting a common fungal pathogen, Candida albicans, reveals that HOCI is a potent killing agent. The laboratory finding is highlighted in the journal mBio.
Many of the most potent human oncoproteins belong to a class of proteins called transcription factors, but designing small molecule drugs that target transcription factors is a major challenge.
The number of patients admitted with opioid use disorder (OUD) and injection-related infections who left the hospital before completing treatment increased significantly between 2016 and 2020 (from 9.3 percent to 17 percent) according to analysis from researchers at the Perelman School of Medicine at the University of Pennsylvania.
The largest review of papers for brain cancer that has spread from the lungs has found abnormalities in the brain cancer and for which licensed drugs could be clinically trialled to find out if they could treat the disease.
A team of Stony Brook University researchers led by Gábor Balázsi, PhD, have been testing drug resistance with mammalian cell lines. Their latest investigation reveals that by taking a part of a DNA amplification from a cell, which causes resistance, and placing it back in, actually stops the drug resistance. Their findings will be published this week in PNAS.
Researchers tease apart the relationships between bacterial languages
The American Society for Pharmacology and Experimental Therapeutics (ASPET) has selected 16 individuals as 2023 ASPET Fellows.
Stay informed! Keep up with the latest research on the COVID-19 virus in the Coronavirus channel on Newswise.
A Yale-led analysis of the genomes of more than 1 million people has shed light on the underlying biology of cannabis use disorder and its links to psychiatric disorders, abuse of other substances such as tobacco, and possibly even an elevated risk of developing lung cancer.
University of B.C. researchers have uncovered startling connections between micronutrient deficiencies and the composition of gut microbiomes in early life that could help explain why resistance to antibiotics has been rising across the globe.
Scientists have developed an ingestible device that can safely monitor vital signs like breathing and heart rate from inside humans. The tool, described November 17 in the journal Device, has the potential to provide accessible and convenient care for people at risk of opioid overdose.
Migraine is more than just a headache. Often the pain is accompanied by nausea, vomiting, light sensitivity, and sound sensitivity. Chronic migraine can be disabling and may prevent many, especially women, from contributing to working life.
The world’s total population is expected to reach 9.9 billion by 2050. This rapid increase in population is boosting the demand for agriculture to cater for the increased demand. Below are some of the latest research and features on agriculture and farming in the Agriculture channel on Newswise.
A study showed that patient pain scores were a good predictor for opioid use, but younger patients and those who hadn’t used opioids before were less likely to take them
An existing drug that targets senescent, or sleeping cells could provide the answer to treating lower back pain, according to a new study.
Jusqu'à la moitié des personnes atteintes d'épilepsie résistante aux médicaments (EFR) peuvent bénéficier d'une intervention chirurgicale. Cependant, dans de nombreuses régions à faibles ressources, la mise en place d'un programme chirurgical nécessite de faire face à de multiples défis, notamment la stigmatisation, le manque de ressources, une formation inadéquate et un financement insuffisant.
Asian malaria mosquito found to spread drug and diagnosis-resistant malaria in Africa.
In a proof-of-concept in ACS’ Nano Letters, a team has designed injectable nanoparticles that released naloxone ― which rapidly reverses opioid overdose effects ― when triggered by blue light. In experiments with mice, this system was activated a month after injection.
New research in the November 2023 issue of JNCCN—Journal of the National Comprehensive Cancer Network suggests that breast cancer patients who have insufficient levels of vitamin D before starting paclitaxel treatment are more likely to experience peripheral neuropathy.