Results from a six-month, multi-site clinical trial called the Wireless Innovation for Seniors with Diabetes Mellitus (WISDM) Study Group have been published by the Journal of the American Medical Association (JAMA).
Scientists have discovered an important cell signalling pathway in the kidney which if stopped, could hold the key to treating chronic kidney disease as well as other deadly conditions, including heart attack and stroke.
Emerging evidence suggests that COVID-19 may actually trigger the onset of diabetes in healthy people and also cause severe complications of pre-existing diabetes.
The national law requiring calorie labeling on menus at large chain restaurants is estimated to prevent tens of thousands of new heart disease and type 2 diabetes cases—and save thousands of lives—in just five years, according to a new study that estimates the law’s impact.
Seven leading diabetes organizations issued a consensus report today highlighting the value of diabetes self-management education and support (DSMES) services as part of comprehensive diabetes medical care. The report provides compelling evidence for the need for increased utilization of DSMES, four key times that DSMES is most beneficial, and specific recommendations for both clinicians and health systems to increase access to and participation in DSMES services.
The COVID-19 pandemic presents new challenges for clinicians caring for infected patients with diabetes, according to new guidance published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
The Endocrine Society has named Robert W. Lash, M.D.—an endocrinologist with more than 25 years of experience in the field—as its interim CEO.
Leading nutrition and food policy experts outline a bold case for strengthening federal nutrition research in a live interactive session as part of NUTRITION 2020 LIVE ONLINE, a virtual conference hosted by the American Society for Nutrition (ASN).
A UCLA research team has identified a new paradigm for understanding the regulation of the immune system, potentially paving the way for new approaches to treating infections and immune-related diseases such as type 1 diabetes and certain cancers.
ENDO Online 2020—the Endocrine Society’s largest-ever meeting—will open with a panel discussion exploring the COVID-19 pandemic’s impact on the endocrinology field.
A new analysis of more than 200,000 people found that eating high-quality carbohydrates, such as whole grains, was associated with a lower risk for type 2 diabetes.
Adults and children with type 1 diabetes will spend an average of $2,500 a year out-of-pocket for health care - but insulin isn't always the biggest expense - new research suggests
Nearly a century after insulin was discovered, an international team of researchers including University of Utah Health scientists report that they have developed the world’s smallest, fully functional version of the hormone, one that combines the potency of human insulin with the fast-acting potential of a venom insulin produced by predatory cone snails. The finding, based on animal studies, could jumpstart the development of insulin treatments capable of improving the lives of those with diabetes.
For patients with diabetes – especially those with lower incomes – preventive drug lists (PDLs) of essential medications available with no deductible can reduce out-of-pocket costs while increasing use of important treatments, reports a study in a June supplement to Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the body normally processes into insulin. The study, published in Diabetes, also revealed one protein—called PRDX4—that may be essential for proinsulin folding and insulin production. The research suggests that boosting PRDX4 levels may be a novel therapeutic approach to improving the health of people with diabetes.
Scientists have identified metabolites in the blood that accurately predict whether a woman will develop type 2 diabetes after experiencing a transient form of illness during pregnancy.
A new cooling insole developed by UT Southwestern scientists reduced the foot temperature of patients with diabetic neuropathy by several degrees, diminishing a significant risk factor for diabetic foot ulcers.
A new UT Southwestern study shows how an effective but largely abandoned treatment for Type 2 diabetes could be used again in combination with another drug to eliminate problematic side effects.
A group of patients with diabetes were surveyed on their understanding of the consent process to have their medical data shared with digital platforms offering innovations to the management of their condition.
A new study suggests that treating a breastfeeding parent with a common diabetes drug may provide male offspring lifelong protection against diabetes and obesity. The study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism. It was chosen as an APSselect article for May.
This study provides a wealth of new data showing how beta cells behave at slightly raised levels of blood glucose - still within the pre-diabetes range. The work provides major additional evidence of a “glucose toxicity” effect that helps to drive the development of both type 1 and type 2 diabetes.
This research, published in Nature, shows how different populations of people share most of the genetic susceptibilities to developing type 2 diabetes but do have some different genetic variations that can make them more or less susceptible to developing the condition.
Obese mice with unhealthy lifestyles gain significantly less weight and avoid type 2 diabetes when they receive viruses transplanted from the stool of lean mice. These are the findings of a new University of Copenhagen study.
The rate of heart attacks, strokes and other cardiovascular complications has improved among people with diabetes over the past 20 years, narrowing the gap in cardiovascular mortality rates between individuals with and without diabetes, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Older men who have lower lean body mass as they age are more prone to developing diabetes, while similar findings were not found in older women, according to a new study published in Journal of the Endocrine Society.
Short-term cold exposure may help people with brown fat burn 15 percent more calories than those without, according to a small study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
The website addresses the need for credible information and a plan to support families with children at home. Health care providers, graduate, and undergraduate students quickly developed a website that serves as a comprehensive single source for high quality COVID-19 customized for families who have a child living with diabetes.
Wake Forest School of Medicine, in partnership with University of North Carolina School of Medicine (UNC), Duke University School of Medicine and North Carolina Agricultural and Technical State University (NC A&T), has been awarded a $5.7 million Diabetes Research Center grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health (NIH).
High-altitude adaptations in the Himalayas may lower risk for some chronic diseases, according to a research team including faculty from Binghamton University, State University of New York, the University of New Mexico, and the Fudan University School of Life Sciences.
Researchers at Washington University School of Medicine in St. Louis have used induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes, transformed the stem cells into insulin-producing cells, used the CRISPR gene-editing tool to correct a defect that caused a form of diabetes, and implanted the cells into mice to reverse diabetes in the animals.
ADCES launches redesigned member platform
A new review suggests that higher-than-normal levels of an enzyme involved in blood clot prevention may be a common risk factor for developing COVID-19—a respiratory disease caused by the novel coronavirus SARS-CoV-2—in some populations. The review is published in Physiological Reviews.
Individuals with diabetes are at increased risk for bacterial, parasitic and viral infections. New research published in Endocrine Reviews, a journal of the Endocrine Society, illuminates how intersections of the coronavirus infection (COVID-19) and type 2 diabetes may require new approaches in treatment for hospitalized patients.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday, throughout the duration of the outbreak.
The behavior of previous coronaviruses together with physiological characteristics of diabetes may help explain why people with diabetes have a higher risk of developing COVID-19, a respiratory disease caused by the novel coronavirus SARS-CoV-2.
Fatty liver disease not associated with alcohol consumption, which is called Nonalcoholic Fatty Liver Disease or NAFLD, affects more than one billion people worldwide. Even in children the numbers are overwhelming, with up to 80 percent of pediatric patients who are considered obese affected worldwide. People with NAFLD can progress to a severe form known as nonalcoholic steatohepatitis (NASH), which puts patients at higher risk for cirrhosis or liver cancer.
There's a higher case fatality rate in type 1 than type 2 diabetes, which suggests different mechanisms for heart failure might be involved in type 1 diabetes.” Given the burden of heart failure in type 1 diabetes, the early identification of patients at particular risk is of importance.
Joslin researchers have found a pathway that can boost the production of (heat-generating, fat-burning) brown fat cells without also creating unhelpful white fat cells. This finding suggests that the pathway the Joslin team uncovered might offer a solution to that challenge.
Doctors need to pay particular attention to patients with endocrine disorders and diabetes mellitus in relation to COVID-19 infections, say leading endocrinologists.
Houston Methodist nanomedicine researchers are studying a new drug delivery system that transports oral medication via triglycerides that could eliminate the need for injections or IV treatments of some biologic drugs for rheumatoid arthritis and other autoimmune diseases. They’re doing this with a diabetes drug that resulted in approximately 25% absorption in mice models, considered very high for an oral drug. The research will appear in Science Advances April 1.
The framework for the AADE7 Self-Care Behaviors were recently published, highlighting changes in diabetes care and management.
Individuals taking a class of steroid hormones called glucocorticoids for conditions such as asthma, allergies and arthritis on a routine basis may be unable to mount a normal stress response and are at high risk if they are infected with the virus causing COVID-19, according to a new editorial published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Obese females that ate a small amount of coconut oil daily, even as part of a high-fat diet, had decreased features of metabolic syndrome, a cluster of risk factors that raise the chances of developing diabetes, heart disease and stroke, an animal study finds. The study results were accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society.
Continuous glucose monitor (CGM) and continuous subcutaneous insulin infusion (CSII) devices are known to improve outcomes in patients with type 1 diabetes (T1D), yet African American and Hispanic patients face barriers to the use of these devices, according to results of a small single-center retrospective study. The results of the ENDO 2020 abstract will be published in the Journal of the Endocrine Society.
Two newer types of medications commonly used to treat type 2 diabetes are similar in their ability to reduce major heart complications, including heart attack, stroke and death from cardiovascular disease, according to research accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.
A type of artificial intelligence called machine learning can help predict which patients will develop diabetes, according to an ENDO 2020 abstract that will be published in a special supplemental section of the Journal of the Endocrine Society.
Adults with type 2 diabetes requiring insulin therapy can safely achieve good blood sugar control using regular human insulin (RHI) in a wearable, patch-like insulin delivery device called V-Go®, a new study finds. Results of the randomized controlled study—which was accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society—suggest “a more affordable option” for insulin therapy than newer insulin types, the researchers said.
Scientists at St. Jude Children’s Research Hospital mapped the epigenetic controls on T cells, which could aid Type 1 diabetes diagnosis and treatment, as well as cancer immunotherapy.
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