Monte Shaheen, MD, and colleagues from around the country recently published a paper in the New England Journal of Medicine about a promising new treatment for melanoma.
Researchers at the University of North Carolina and NC State have created the first “smart insulin patch” that can detect increases in blood sugar levels and secrete doses of insulin into the bloodstream whenever needed.
Patients with atrial fibrillation who stopped taking blood thinners before they had elective surgery had no higher risk of developing blood clots and less risk of major bleeding compared to patients who were given a “bridge” therapy, according to research led by Duke Medicine.
CGRP monoclonal antibodies appear to significantly reduce the frequency of migraine in human clinical trials, potentially changing the landscape for migraine treatment. Headache specialist Sid Kapoor, MD, discusses the enormous potential -- and pitfalls-- facing the drug class' road to FDA approval.
An amino acid whose role in the body has been all but a mystery appears to act as a potent seizure inhibitor in mice, according to a study by researchers at Johns Hopkins.
By manipulating the activity of Activin receptors in the brain, researchers were able to increase or decrease cocaine-taking and relapse behavior in animal models. The study focused on receptors in regions of the brain involved in pleasure and reward.
Infants and children who are given prescription acid-reducing medications face a substantially higher risk of developing Clostridium difficile infection, a potentially severe colonic disorder.
Migraine researchers and clinicians are excited about a new class of drugs called Calcitonin Gene-Related Peptide (CGRP) monoclonal antibodies, which are showing promise in preventing attacks in high-frequency episodic migraine and chronic migraine. Numerous studies on these medications are being presented at this week's American Headache Society scientific meeting.
Women who were exposed to higher levels of the pesticide DDT in utero were nearly four times more likely to be diagnosed with breast cancer as adults than women who were exposed to lower levels before birth, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
A decade of work at Johns Hopkins has yielded a computer formula that predicts which mutations are likely to have the largest effect on the activity of "genetic dimmer switches," suggesting new targets for diagnosis and treatment of many complex diseases.
Adults across the country share the same top concern about the new alcohol-on-the-go product: potential misuse among underage youth.
A series of immersive virtual reality experiments has confirmed that the human brain’s internal navigation system works in the same fashion as the grid cell system recently found in other mammals.
Brain tumor stem cells can resist treatment and regrow tumors, but scientists have identified a vulnerability in these cells that could lead to a new approach in battling deadly brain tumors.
Scientists and physicians from federally designated cancer centers used molecular and genetic analysis to develop a new method of classifying low-grade brain tumors. The approach reduces the role of individual observers’ assessments of the tumors’ appearance.
While participating in physical activities such as bike riding, dancing, walking and gardening and mentally stimulating activities such as crosswords and reading may reduce the risk of Alzheimer’s disease, they may not do so by affecting the underlying markers for the disease, according to a study published in the June 10, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Adults who use proton pump inhibitors are between 16 and 21 percent more likely to experience a heart attack than people who don't use the commonly prescribed antacid drugs, according to a massive new study by Houston Methodist and Stanford University scientists.
Researchers at Children’s Hospital Los Angeles have demonstrated that adolescents and young adults with congenital adrenal hyperplasia (CAH) have significantly increased amounts of abdominal fat tissue, placing them at greater risk for harmful conditions linked to obesity, including cardiovascular disease (CVD).
Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that the common antibiotic azithromycin kills many multidrug-resistant bacteria very effectively — when tested under conditions that closely resemble the human body and its natural antimicrobial factors. The researchers believe the finding, published June 10 by EBioMedicine, could prompt an immediate review of the current standard of care for patients with certain so-called “superbug” infections.
A new paper in the British Medical Journal by Jan Blustein, MD, PhD, of New York University’s Wagner School and a professor of Medicine and Population Health at NYU School of Medicine and Jianmeng Liu of Peking University examines the evidence as to whether newborns delivered by C-section are more likely to develop chronic diseases later in life.
A research paper published in The Lancet Oncology showed that a single dose of the human papillomavirus vaccine Cervarix® may prevent HPV-related cervical cancer.
Brain inflammation caused by chronic nerve pain alters activity in regions that regulate mood and motivation, suggesting for the first time that a direct biophysical link exists between long-term pain and the depression, anxiety and substance abuse seen in more than half of these patients, UC Irvine and UCLA researchers report.
The witness on the stand says he saw the accused at the scene of the crime. Is he sure? How sure? The jury’s verdict could hinge on that level of certainty. Many decisions we make every day are influenced by our memories and the confidence we have in them. But very little is known about how we decide whether we can trust a memory or not. Cedars-Sinai researchers have identified a unique set of neurons in the medial temporal lobe, an area of the brain where memories and memory-based decisions are processed. They show that the activity of these neurons is indicative of the confidence by which a memory will be retrieved.
The 50 hospitals in the United States with the highest markup of prices over their actual costs are charging out-of-network patients and the uninsured, as well as auto and workers’ compensation insurers, more than 10 times the costs allowed by Medicare, new research suggests. It’s a markup of more than 1,000 percent for the same medical services.
Trending news releases with the most views in a single day. Topics include: marijuana exposure in children, female viagra, botox for nerve pain, genetics, cancer and bone marrow transplants, stroke, dengue fever, and memory loss in epilepsy.
Researchers say that the ability to "diagnose" the skills teen drivers lack may provide opportunities for better driving practice in a safe environment, so that teens are better prepared to navigate hazardous situations when they take to the road alone.
Physical activities, such as walking, as well as aerobics/calisthenics, biking, gardening, golfing, running, weight-lifting, and yoga/Pilates are associated with better sleep habits, compared to no activity, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. In contrast, the study shows that other types of physical activity – such as household and childcare -- work are associated with increased cases of poor sleep habits. The full results of the study (Abstract #0246) will be presented during the poster session on Monday, June 8, at SLEEP 2015, the 29th annual meeting of the Associated Professional Sleep Societies LLC, June 6-10, in Seattle, WA.
Scientists at Duke Medicine have produced a 3-D map of the human brain stem at an unprecedented level of detail using MRI technology. In a study to be published June 3 in Human Brain Mapping, the researchers unveil an ultra high-resolution brain stem model that could better guide brain surgeons treating conditions such as tremors and Parkinson’s disease with deep brain stimulation (DBS).
By knowing that AMPK is vital for maintaining muscle mass with aging, researchers can now try to adapt exercise regimes and existing drugs to switch on AMPK in muscle more effectively. The development of new selective activators of the AMPK pathway in muscle may also be effective to prevent muscle loss with aging.
People with achromatopsia, an inherited eye disorder, see the world literally in black and white. Worse yet, their extreme sensitivity to light makes them nearly blind in bright sunlight. Now, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health System have identified a previously unknown gene mutation that underlies this disorder.
In Science Advances, University at Buffalo researchers will report that they have managed to turn E. coli into tiny factories for producing new forms of the popular antibiotic erythromycin — including three that were shown in the lab to kill drug-resistant bacteria.
Simple measures of kidney function and damage may be just as good at predicting who is at risk for heart failure and death from heart attack and stroke as traditional tests of cholesterol levels and blood pressure, new Johns Hopkins Bloomberg School of Public Health-led research suggests.
Scientists have found that stage IIIb to IV melanoma patients treated with a modified cold sore (herpes) virus had improved survival. The results of the findings were published recently in the Journal of Clinical Oncology.
Scientists at the University at Buffalo have identified the mechanisms behind a genetic mutation that produces certain autistic behaviors in mice, as well as therapeutic strategies to restore normal behaviors.
Cannabis plus alcohol is one of the most frequently detected drug combinations in car accidents, yet the interaction of these two compounds is still poorly understood. A study appearing online today in Clinical Chemistry, the journal of AACC, shows for the first time that the simultaneous use of alcohol and cannabis produces significantly higher blood concentrations of cannabis’s main psychoactive constituent, Δ9-tetrahydrocannabinol (THC), as well as THC’s primary active metabolite, 11-hydroxy-THC (11-OH-THC), than cannabis use alone.
The microbiome of a toddler’s gut may influence their behavior, a new study suggests. Scientists found correlations between temperament and the presence of specific types of intestinal bacteria in both girls and boys. The researchers aren’t looking for a way to help parents modify the ‘terrible twos,’ but for clues about how - and where - chronic illnesses like obesity, asthma, allergies and bowel diseases start.
A team including scientists from Albert Einstein College of Medicine and the U.S. Army Medical Research Institute of Infectious Diseases has identified the molecular “lock” that the deadly Ebola virus must pick to gain entry to cells. The findings, made in mice, suggest that drugs blocking entry to this lock could protect against Ebola infection.
New UK research has challenged the assumption that people with rheumatoid arthritis always take their medication as prescribed.
Attitudes and beliefs about CAM were found to be a better predictor of CAM usage than socio-demographic factors alone – such as race, sex, or education – which are often used to describe CAM users but stop short of fully explaining what drives people to use them.
Reporting on their study with lab-grown human cells, researchers at The Johns Hopkins University and the University of Maryland say that blocking a second blood vessel growth protein, along with one that is already well-known, could offer a new way to treat and prevent a blinding eye disease caused by diabetes.
New research from UAB shows that high-heeled-shoe-related injuries doubled between 2002 and 2012. The frequency and severity of those injuries were sufficient to make the investigators suggest that wearing the appropriate shoes for the appropriate occasion and being aware of one’s surroundings are good ideas.
People with depression may be more likely to develop Parkinson’s disease, according to a large study published in the May 20, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints.
A new study in animals suggests that skipping meals sets off a series of metabolic miscues that can result in abdominal weight gain.
Why do some cancer cells break away from a tumor and travel to distant parts of the body? A team of oncologists and engineers from the University of Michigan teamed up to help understand this crucial question.
Researchers at the University of Colorado suggest that the portion of the brain devoted to hearing can become reorganized even with early-stage hearing loss, and may play a role in cognitive decline. They have applied fundamental principles of neuroplasticity, the ability of the brain to forge new connections, to determine the ways it adapts to hearing loss, as well as the consequences of those changes, and their findings will be presented at ASA’s 169th meeting.
In the first study of its kind, former National Football League (NFL) players who lost consciousness due to concussion during their playing days showed key differences in brain structure later in life.
Many parents of children age 5-17 don’t discuss behavioral or emotional issues that could be signs of potential health problems with their doctors.
Queen's University Belfast has helped to trial a new treatment that could extend the life of cystic fibrosis patients.
The study followed almost 140,000 adults aged 35 to 70 over four years in 17 countries. Their muscle strength was measured using a handgrip dynamometer. They were taking part in the institute’s Prospective Urban-Rural Epidemiology (PURE) study.
Secondhand exposure to cannabis smoke under “extreme conditions,” such as an unventilated room or enclosed vehicle, can cause nonsmokers to feel the effects of the drug, have minor problems with memory and coordination, and in some cases test positive for the drug in a urinalysis. Those are the findings of a Johns Hopkins University School of Medicine study, reported online this month in the journal Drug and Alcohol Dependence.
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