Feature Channels: Bone Health

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Johns Hopkins Kimmel Cancer Center researchers developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.

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Next-generation Genomic Sequencing could help identify infecting organisms and guide treatment for patients with joint-replacement infection

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Los pacientes con gammapatía monoclonal de significado incierto corren más riesgo de avanzar hacia mieloma múltiple u otro cáncer afín, incluso después de 30 años de estabilidad.

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A Hospital for Special Surgery study finds that patients who had an education session with a physical therapist and access to a web-based microsite prior to joint replacement achieved physical therapy goals more quickly compared to patients who did not have the session or access to the site.

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Long-term consequences can happen years after an ACL injury. One Michigan Medicine researcher is investigating new therapies that could minimize those unwanted effects.

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Penn Orthopaedics and Princeton Orthopedic Associates have announced a new strategic alliance in an effort to enhance and continue to improve orthopaedic care to patients in New Jersey and Pennsylvania. As part of the Penn Medicine Orthopaedic Specialty Network, physicians and surgeons at each entity will work collaboratively across state lines to expand patients’ access to highly specialized orthopaedic care, while improving care team communication and processes, and collecting data to help physicians advance clinical research and care.

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Mayo Clinic的研究人员所进行的一项研究发现，大多数被怀疑患有原因不明脊髓炎的患者后来有另外一种具体的诊断。该研究发表在美国神经病学学会（American Academy of Neurology）的医学杂志 神经病学（Neurology）上。

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Significant, quick reduction in scoliosis curves with two yoga poses

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Un estudio de los investigadores de Mayo Clinic descubrió que la mayoría de los pacientes en quienes se sospecha una inflamación de causa desconocida de la médula espinal reciben otro diagnóstico específico. El estudio se publicó en Neurology.

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What's the best way to rate the quality and quantity of research produced by orthopaedic surgery residency programs? A new "research impact ranking" provides a more objective approach to assessing and comparing research productivity at US orthopaedic departments, according to a study in the November Journal of Orthopaedic Trauma (JOT), published by Wolters Kluwer.

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More than 1 million people undergo total joint replacements each year, and nearly 10,000 will develop infections. To reduce this infection risk, a Houston Methodist orthopedic surgeon created small antibiotic beads that are implanted with the new joint to slowly release medicine for several weeks.

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A study by Mayo Clinic researchers found that most patients with suspected spinal cord inflammation of unknown cause have an alternative, specific diagnosis. The research is published in Neurology, the medical journal of the American Academy of Neurology.

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The proteasome inhibitor carfilzomib has taken on an increasing role in the treatment of multiple myeloma, but new research from the Abramson Cancer Center of the University of Pennsylvania shows the therapy comes with the risk of cardiovascular problems in a higher than expected percentage of patients.

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In this month’s release, find new embargoed research that links increased hepatitis C numbers to the opioid epidemic, shows Medicaid expansion increasing cancer diagnoses, the ACA expanding breastfeeding and the prevalence of osteoarthritis growing

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Some secrets to repairing our skeletons might be found in the silky webs of spiders, according to recent experiments guided by supercomputers. Scientists involved say their results will help understand the details of osteoregeneration, or how bones repair themselves.

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Doctors at The Ohio State University Wexner Medical Center are using a procedure called Subchondroplasty to give patients with damaged hips more treatment options and ultimately avoid replacement surgery.

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Muscle paralysis rapidly causes inflammation in nearby bone marrow, which may promote the formation of large cells that break down bone, a new study finds.

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Nearly four out of five diabetic patients with severe cases of a disabling condition called Charcot foot were able to walk normally again following surgery, a Loyola Medicine study has found.

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Some complications are more common when total knee replacement surgery is done as an outpatient or same-day procedure, reports a study in the December 6, 2017 issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.

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An observational study by researchers at Mayo Clinic has found that increasing physical activity not only decreased the risk of death from all causes but also decreased the risk of death specifically from lymphoma.

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A new study finds that female veterans—one of the fastest growing populations receiving treatment through the Veterans Administration (VA) health care system—experience improvement in low back pain with a course of chiropractic care, according to the American Chiropractic Association (ACA).

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Researchers at the Center for Integrative Nanotechnology Sciences at the University of Arkansas at Little Rock and at the University of Tennessee, Knoxville, helped saved the life of an injured baby alpaca using the NuCress™ scaffold, a nanomaterial-based bone regeneration device.

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Dr. Eunice Wang was invited to discuss results of a phase II clinical trial of crenolanib for adults with AML at the ASH 2017 annual meeting, and Dr. Kara Kelly, senior author of an oral abstract on outcomes disparities among children and adolescents with Hodgkin lymphoma.

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Two investigational immunotherapy approaches, including chimeric antigen receptor (CAR) T cell therapy, have shown encouraging results in the treatment of multiple myeloma patients who had relapsed and were resistant to other therapies. Researchers from the University of Pennsylvania’s Abramson Cancer Center administered CAR T cells to patients following chemotherapy, with 64 percent of patients responding in a clinical trial. In a separate study, patients got an infusion of an experimental monoclonal antibody, which resulted in an overall response rate of 60 percent. Both of these investigational approaches targeted a receptor called B-Cell Maturation Antigen (BCMA), which is highly expressed in myeloma and thus a promising target for treatment.

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A group of investigators from Mayo Clinic and multiple academic research centers in Italy have identified a genetic model for predicting outcomes in patients with primary myelofibrosis who are 70 years or younger and candidates for stem cell transplant to treat their disease.

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The American College of Rheumatology (ACR) welcomes members of the press to write about rheumatology research presented the Winter Rheumatology Symposium in Snowmass Village, CO on January 20-26, 2018.

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There is a more than 50 per cent reduction in the occurrence of headaches with the atraumatic needles, and also more than a 50 per cent reduction in patient readmissions and return to emergency rooms for narcotics or blood patches.

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Findings Could Have Implications for Systemic as Well as Bone Conditions

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Research from the University of Warwick indicates that most people are in favour of newborn screening for the potentially deadly condition spinal muscular atrophy (SMA).

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Members of the media can now register to cover the latest advances in hormone health and science at ENDO 2018, the Endocrine Society’s 100th Annual Meeting & Expo. The meeting will be held March 17-20, in Chicago, Ill.

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Incidental durotomy—small tears of the outer membrane of the spinal cord—are a common occurrence in spinal surgery, and may lead to litigation. Most malpractice cases associated with dural tear end in a ruling in favor of the surgeon, reports a study in the journal Spine, published by Wolters Kluwer.

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CHICAGO — For J. William Charboneau, M.D., life is a journey of unknown possibilities, filled with family. And Tuesday, Nov. 28, with family both personal and professional by his side and in the audience, Dr. Charboneau’s journey reached another destination.

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Small amounts of artificial vanilla extract, also known as vanillin,are in a wide range of products, from baked goods to perfumes. But vanillin’s versatility doesn’t stop there.In a recent mouse study reported in ACS’ Journal of Agricultural and Food Chemistry, researchers report that this compound could also prevent or reduce psoriatic skin inflammation.

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People whose genetic makeup triggers a later-than-average start to puberty have lower bone mineral density, especially in their lower spine. Because adolescence is a critical period for accruing bone, this effect may increase a person’s risk of osteoporosis and bone fractures later in life.

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The study, published in the medical journal Osteoarthritis and Cartilage, found that monocytes, the white blood cells necessary to regulate immune responses, were more activated and pro-inflammatory in women with osteoarthritis, and that elevated inflammation and body mass index were associated with this increased activation.

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Researchers have demonstrated that the drug palovarotene suppresses the formation of bony tumors (osteochondromas) in models of multiple hereditary exostoses (MHE). The research, published in the Journal of Bone and Mineral Research, is an important step toward an effective pharmacological treatment for MHE, a rare genetic condition that affects about 1 in 50,000 people worldwide.

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University of Colorado Boulder researchers have developed a potent, drug-like compound that could someday revolutionize treatment of rheumatoid arthritis and other autoimmune diseases.

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Patients and family members are either neutral or uncomfortable with the idea of "overlapping" or "concurrent" surgery, where the attending surgeon isn't present in the operating room for part of the procedure, according to survey results published in the November 15, 2017 issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.

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A study from the Keck School of Medicine of USC finds that a peptide only found in Old World monkeys has the potential to stop rheumatoid arthritis progression better than established treatments.

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Using a different marker to track a patient’s glycemic levels could help improve outcomes after surgery for diabetic and non-diabetic patients alike.

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Researchers are calling for a randomised clinical trial to investigate the potential role of vitamin D supplementation in improving live birth rates following assisted reproduction treatment (ART).

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Two NDSU researchers have published a paper giving high marks to a program designed to help aging adults prevent falls.

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Rural counties continue to rank lowest among counties across the U.S., in terms of health outcomes. A group of national organizations including the Robert Wood Johnson Foundation and the National 4-H Council are leading the way to close the rural health gap.

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More than half of the babies with infantile-onset spinal muscular atrophy (SMA) who were treated with nusinersen (Spinraza) gained motor milestones, compared to none of the babies in the control group. Infants treated with the drug also had 63 percent lower risk of death. These final results from the 13-month, international, randomized, multicenter, sham procedure-controlled, phase 3 trial called ENDEAR were published in the New England Journal of Medicine.

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The Academy of Rheumatology Medical Educators at Hospital for Special Surgery (HSS) has created a stimulating academic environment for educators, promoted teaching excellence and supported innovative research in rheumatology education.

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A combination of race and socioeconomic factors play a role in hip replacement outcomes, according to a study at Hospital for Special Surgery (HSS).

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While MRI scans of the sacroiliac joints positive for inflammation are not always specific in patients with axial spondyloarthritis (axSpA), their prevalence in healthy individuals demonstrates the importance of additional diagnostic measures for axSpA.

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An internet-based health education and self-management program that offers monthly calls with health coaches improved health-related quality of life for participating teens with juvenile idiopathic arthritis, according to research presented at the 2017 ACR/ARHP Annual Meeting in San Diego.

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A large percentage of patients with end-stage knee, hip and spine osteoarthritis use opioids to manage their chronic pain, especially those who are younger or have symptoms of depression, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.