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Article ID: 705535

One type of brain cell may invite Alzheimer’s

Ohio State University

Researchers found that excitatory neurons – those that are more likely to trigger an action (as opposed to inhibitory neurons, which are less likely to prompt neural activity) – are more vulnerable to accumulations of abnormal tau protein, which is increasingly being implicated in Alzheimer’s disease.

17-Dec-2018 11:05 AM EST
  • Embargo expired:
    17-Dec-2018 11:00 AM EST

Article ID: 705389

Neurons with Good Housekeeping Are Protected from Alzheimer’s

Columbia University Irving Medical Center

A new study finds that some brain cells protect themselves from Alzheimer’s with a cellular cleaning system that sweeps away toxic proteins associated with the disease.

13-Dec-2018 8:05 AM EST
  • Embargo expired:
    17-Dec-2018 11:00 AM EST

Article ID: 705416

Tuning Arousal to Boost Information Transmission in the Brain

Columbia University School of Engineering and Applied Science

A new study from biomedical engineer Qi Wang, who is developing innovative ways of selectively activating neural circuitry to enhance perception and cognition, demonstrates a major advance in understanding how the locus coeruleus (LC) modulates information processing in the thalamus. Wang found that activating the LC improves the transmission of information about different features of sensory stimuli from the thalamus to the cerebral cortex, and subsequently perceptual performance in perceptual tasks.

13-Dec-2018 11:05 AM EST

Article ID: 705504

Research suggests path to vaccine or drug for late-onset Alzheimer’s

UT Southwestern Medical Center

UT Southwestern researchers have succeeded in neutralizing what they believe is a primary factor in late-onset Alzheimer’s disease, opening the door to development of a drug that could be administered before age 40, and taken for life, to potentially prevent the disease in 50 to 80 percent of at-risk adults.

14-Dec-2018 2:05 PM EST
  • Embargo expired:
    13-Dec-2018 11:00 AM EST

Article ID: 705314

New Genetic Clues to Early-Onset Form of Dementia

Washington University in St. Louis

In an effort to better understand frontotemporal dementia, an international team of researchers, led by Washington University School of Medicine in St. Louis, has found that a lone mutation in a single gene that causes an inherited form of the disorder makes it harder for neurons in the brain to communicate with one another, leading to neurodegeneration.

12-Dec-2018 10:45 AM EST
  • Embargo expired:
    12-Dec-2018 4:00 PM EST

Article ID: 705139

Risk of Dementia Increased Among Female Veterans with TBI, PTSD, Depression

American Academy of Neurology (AAN)

Female military veterans who have traumatic brain injury, post-traumatic stress disorder or depression long after their service may be more likely to later develop dementia than female veterans without those conditions, according to a study published in the December 12, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

7-Dec-2018 3:05 PM EST

Article ID: 705252

New discoveries predict ability to forecast dementia from single molecule

UT Southwestern Medical Center

Scientists who recently identified the molecular start of Alzheimer’s disease have used that finding to determine that it should be possible to forecast which type of dementia will develop over time – a form of personalized medicine for neurodegenerative diseases.

11-Dec-2018 12:05 PM EST

Article ID: 705148

New Generation of Therapeutics Based on Understanding of Aging Biology Show Promise for Alzheimer's Disease

Alzheimer's Drug Discovery Foundation

A scientific strategy that explores therapeutic targets based on the biology of aging is gaining ground as an effective approach to prevent and treat Alzheimer's disease, according to research published in the December 7, 2018 online issue of Neurology®.

10-Dec-2018 3:05 PM EST

Article ID: 705180

Two Compounds in Coffee May Team Up to Fight Parkinson’s

Rutgers University-New Brunswick

Rutgers scientists have found a compound in coffee that may team up with caffeine to fight Parkinson’s disease and Lewy body dementia – two progressive and currently incurable diseases associated with brain degeneration.

10-Dec-2018 12:05 PM EST

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