Opposites don’t actually attract. That’s the takeaway from a sweeping CU Boulder analysis of more than 130 traits and including millions of couples over more than a century.
The linguist have developed the comparison of the genetic code with language where nucleotides act as letters, and introduced the concept of “a semiotic nucleotide” – the minimal element which makes it possible distinguishing between codons – coding units of DNA.
The largest genetic study of its kind, coordinated by the International League Against Epilepsy (ILAE), has discovered specific changes in our DNA that increase the risk of developing epilepsy.
A group of researchers has unearthed the secrets behind a tiny but crucial protein that shuttles zinc ions (Zn2+) within our bodies. The discovery offers a deeper understanding of how our cells maintain optimal health.
A new study from the University of Michigan Department of Neurosurgery and Rogel Cancer Center shows promising early results that a therapy combining cell-killing and immune-stimulating drugs are safe and effective in extending survival for patients with gliomas, a highly aggressive form of brain cancer.
UChicago Medicine Comer Children’s Hospital was one of three sites to enroll patients in a clinical trial to test a potentially curative stem cell gene therapy for sickle cell disease. The results were promising.
A multi-site, five-year study led by a MedStar Heart & Vascular Institute cardiologist and fellow researchers from across the country have demonstrated the benefits of routine genetic testing for patients with advanced disease from dilated cardiomyopathy (DCM), a disease of the heart muscle and their at-risk family members.
A special antibody derived from llamas —called a nanobody — can stop the misfolding and the activation of Rhodopsin, a molecule whose mutations can lead to blindness.
High-quality sequencing of nearly the entire kākāpō population, funded through a Genomics Aotearoa project, is helping New Zealand to manage the health of this critically endangered species.
PNP editing emerges as a versatile and programmable tool for site-specific DNA manipulations.
The hereditary molecule DNA can store a great deal of information over long periods of time in a very small space.
Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer.
A new study published in iScience, by Hong Wang, PhD, an Associate Member at the Monell Chemical Sense Center, and colleagues sheds light on the mechanisms involved in the complex interplay between taste perception and immune function. Their work also highlights the potential of a sequencing tool for investigating epigenetic mechanisms that affect taste-cell gene expression.
Now, scientists at The Wistar Institute have discovered a potential target for gastric cancers associated with Epstein-Barr Virus; study results were published in the journal mBio.
A new study led by a researcher at New York Institute of Technology provides insight that could change how scientists and clinicians understand genetic predisposition to breast cancer, a condition that affects one in eight U.S. women in her lifetime.
CureMD, a leading provider of comprehensive technology solutions for community oncology, is proud to announce its partnership with Tempus, a leader in artificial intelligence and precision medicine, to integrate Tempus' advanced genomic testing capabilities into CureMD's cutting-edge Electronic Health Record (EHR) system.
Clopidogrel is a commonly prescribed medication used to prevent further heart attacks after an initial event. It needs to be activated in the body to be effective.
A $3 million, five-year award from the National Institute of Environmental Health Sciences of the NIH aims to discover and validate the gene Х heavy metal (GXM) interactions in human livers and to understand their role in nonalcoholic fatty liver disease
Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models.
A new study highlights the potential of artificial DNA structures that, when fitted with antibodies, instruct the immune system to specifically target cancerous cells.
Researchers at the University of Idaho have found a unique, non-invasive way to identify polar bears in the Arctic by scraping DNA from a bear’s paw print.
Imagine a few roughly cut slices of bread on a plate. With just those slices, could you picture, in fine detail, the loaf they came from?
A combination approach of increasing the SIRT3 protein and inhibiting PARPs (poly-ADP ribose polymerase) helps rescue motor endurance of mice modeling the neuromuscular disease spinal bulbar and muscular atrophy (SBMA), also known as Kennedy’s disease, according to a new study by Philadelphia College of Osteopathic Medicine (PCOM) researchers.
Humans have a positive view of nature. But is this due to an approach we have learned while growing up, or is it something we are born with?
Joan Conaway, Ph.D., Vice Provost and Dean of Basic Research at UT Southwestern Medical Center, has been elected President-Elect of the American Society of Biochemistry and Molecular Biology (ASBMB), one of the largest scientific societies in the world.
Doctors try to improve the life of a four-year-old with a rare genetic disease and other patients like her
Researchers at Rutgers and Emory University are gaining insights into how schizophrenia develops by studying the strongest-known genetic risk factor.
Todd Aguilera, M.D., Ph.D., Assistant Professor of Radiation Oncology and member of the Experimental Therapeutics Program in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center, has been named one of 11 inaugural Cancer Moonshot Scholars. The national program recognizes a cohort of early-career investigators from underrepresented groups who have been identified as emerging leaders in cancer research and innovation.
Parents can be so protective of a child with congenital heart disease they often forget what comes next. When should they start learning to take care of their own condition? Two Penn State Health experts share their views.
Research team used advanced sequencing technology to analyze Ötzi’s genome to obtain a more accurate picture of the Iceman’s appearance and genetic origins.
Jane Carlton, PhD, a biologist and leader in the field of comparative genomics, has joined the Johns Hopkins Bloomberg School of Public Health as director of the Johns Hopkins Malaria Research Institute. She assumed the role on August 1.
Researchers at Tel Aviv University have developed a computational model that makes it possible to predict each woman's genetic risk of developing breast cancer based on her genetic profile.
In a development that could accelerate the discovery of new diagnostics and treatments, researchers at Children’s Hospital of Philadelphia (CHOP) have developed a versatile and low-cost technology for targeted sequencing of full-length RNA molecules.
Gliomas are incurable brain tumors. Researchers are trying to unlock the mysteries of how they originate from normal cells, which may lead to better treatments.
Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes. These enzymes are growing increasingly common, appearing worldwide in clinical samples in a range of drug-resistant bacteria.
Scientists from Italy used high-throughput 16S rRNA amplicon sequencing, which gives a detailed picture of what microbes are present and in what proportions, to understand how microbes make mozzarella.
Bioengineers can tailor the genomes of cells to create “cellular therapies” that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch on bioengineered genes without occasionally turning on some of the cell’s naturally occurring genes.
We have all felt the workings of the so called “brain-gut-axis”, how our intestines get affected, for example, by stress. But still, researchers don’t know a lot about the relation between our gut and our brain.
La inteligencia artificial (IA) está capturando la imaginación del público a medida que el ritmo de la innovación se acelera considerablemente y las herramientas de IA fáciles de usar ofrecen nuevas posibilidades para transformar industrias enteras.
A new genomic study conducted by researchers on schistosomiasis-associated colorectal cancer (SA-CRC) provides critical insights into the unique mutational landscape and the potential treatment pathways for the disease. SA-CRC, linked to chronic inflammation caused by schistosomal ova deposition in the intestine, presents different epidemiological and clinical outcomes than sporadic colorectal cancer (S-CRC).
Nanovesicles can be bioengineered to target cancer cells and deliver treatments directly, according to research at Binghamton University, State University of New York.
Despite decades of progress, the origin of life remains one of the great unsolved problems in science.
Artificial intelligence (AI) is capturing the public imagination as the pace of innovation accelerates sharply and easy-to-use AI tools offer new possibilities to transform whole industries.
Gene therapy might offer a one-time, sustained treatment for patients with serious alcohol addiction, also called alcohol use disorder, according to a new study led by a researcher at The Ohio State University Wexner Medical Center and College of Medicine.
Patients with the genetic disorder hemophilia A receive factor VIII protein replacement treatments to replenish this clotting protein in their blood, thus preventing dangerous bleeding. Unfortunately, about 30 percent of these patients develop antibodies against the treatment and until now, despite more than 80 years of clinical experience with this complication, little has been known about its mechanism.
A new study from clinicians and researchers at the University of Michigan Rogel Cancer Center, U-M Department of Pathology and the Michigan Center for Translational Pathology reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations.
Ever since gene editing became feasible, researchers and health officials have sought tools that can quickly and reliably distinguish genetically modified organisms from those that are naturally occurring. Now, such tools exist.
A new study presents a promising treatment method for so-called fusion-driven cancers, which are currently often difficult to cure. These fusion-driven cancers are caused by an error in cell division that creates a fusion of different genes. This fusion causes the cancer and drives the uncontrolled cell growth.
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