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Adjuvants Improve Immune Response to H7N9 Flu Vaccine

In a phase 2 trial that included nearly 1,000 adults, the AS03 and MF59 adjuvants (a component that improves immune response of inactivated influenza vaccines) increased the immune responses to two doses of an inactivated H7N9 influenza vaccine, with AS03-adjuvanted formulations inducing the highest amount of antibody response, according to a study in the July 21 issue of JAMA.

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Discovery Points to a New Path Toward a Universal Flu Vaccine

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The conventional flu vaccine protects only against a few specific strains of flu. However, experiments by Rockefeller University researchers and their colleagues show that by including modified antibodies within the vaccine it may be possible to elicit broad protection against many strains simultaneously.

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Scientists Identify “Decoy” Molecule That Could Help Sharply Reduce Risk of Flu Death

The flu virus can be lethal. But what is often just as dangerous is the body’s own reaction to the invader. Now, a University of Maryland School of Medicine researcher has identified a “decoy” molecule that can rein in this runaway inflammatory response.

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Wistar Scientists Pinpoint Mutations Responsible for Ineffectiveness of 2014-2015 Flu Vaccine

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Viruses like influenza have the ability to mutate over time, and given that the flu vaccines administered during the 2014-2015 season were largely ineffective at preventing the spread of the flu, it appears the virus that recently circulated had taken on mutations not accounted for when last year’s vaccine was developed. Now, researchers at The Wistar Institute identified specific mutations that influenza recently acquired to escape the current vaccine design.

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Trending Stories Report for 16 June 2015

Trending news releases with the most views in a single day. Topics include: An anonymous donor for cancer research, solar storms and incidences of rheumatoid arthritis, vulnerabilities in genome’s ‘Dimmer Switches’, new treatments for Alzheimer's, How people make decisions for or against flu vaccinations.

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Personal Experience a Major Driver in Decision for or Against Flu Vaccination

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Convincing someone to receive the annual flu vaccine goes beyond clever messaging and well-written public service announcements, University of Georgia research finds. The study, led by UGA’s Glen Nowak, outlines both the barriers and facilitators that motivate people in their flu vaccine decisions.

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Virus Evolution and Human Behavior Shape Global Patterns of Flu Movement

The global movement patterns of all four seasonal influenza viruses are illustrated in research published today in the journal Nature, providing a detailed account of country-to-country virus spread over the last decade and revealing unexpected differences in circulation patterns between viruses.

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First Case in Texas: Four Ways to Protect Against West Nile Virus from Dr. Ross Tobleman

Follow the "four Ds" to prevent infection and decrease the spread of West Nile Virus this summer.

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Measles-Flu Comparison Yields Insights for Vaccine Design

By comparing flu viruses to the virus that causes measles, researchers fine-tuned a tool that may enable faster vaccine design.

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Vaccines Developed for H5N1, H7N9 Avian Influenza Strains

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Researchers have developed vaccines for H5N1 and H7N9, two new strains of avian influenza that can be transmitted from poultry to humans. The strains have led to the culling of millions of commercial chickens and turkeys as well as the death of hundreds of people.