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One Injection Stops Diabetes in Its Tracks

Treatment reverses symptoms of type 2 diabetes in mice without side effects.

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Most Emergency Department ‘Super-Frequent Users’ Have a Substance Abuse Addiction

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A vast majority of so-called “super-frequent user” patients who seek care in the Emergency Department (ED) have a substance abuse addiction, according to a Henry Ford Hospital study. A patient is considered a super-frequent user who visits the ED at least 10 times a year.

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Mount Sinai Presents Important Findings at 2014 American Urological Association Annual Meeting

Immune Response to Prostate-Specific Antigen, Live Birth Rate Adversely Affected by Increasing Paternal Age, Comparison of Treatment Modalities for Benign Prostatic Hyperplasia, Understanding Psychosocial and Supportive Needs Following Cystectomy

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Biochemists Reduce Sickling and Progression of Sickle Cell Disease in Mice

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New preclinical research on the molecular mechanisms responsible for sickle cell disease could aid efforts to develop much needed treatments for this devastating blood disorder that affects millions worldwide.

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Gender Differences Stand Out in Measuring Impact of Viagra as Therapy for Heart Failure

New animal studies by Johns Hopkins cardiovascular researchers strongly suggest that sildenafil, the erectile dysfunction drug sold as Viagra and now under consideration as a treatment for heart failure, affects males and females very differently.

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Watching HIV Bud from Cells

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University of Utah researchers devised a way to watch newly forming AIDS virus particles “budding” from human cells without interfering with the process. The method shows a protein named ALIX gets involved during the final stages of virus replication, not earlier, as was believed previously.

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Searching for Drugs in Dirt, Researchers Call on Citizen Scientists

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Microbes are not only a rich source of disease, but also a rich source of medicines, and experts think many life-saving compounds produced by as-yet-unnamed bacteria are awaiting discovery. But they don’t always give up their secrets easily. Researchers must know where to look to find promising bacteria, and how to get them to grow in the lab, the traditional route to identifying potentially valuable molecules they produce.

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Dentist Appointment “Do’s and Don’t’s” For Best Results

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Many dread a trip to the dentist but there are important things you need to do, and not do, in advance to have a successful visit. Communicating with your dentist before the visit is often critical. “If you have experienced a serious health condition such as a surgery or been diagnosed with a chronic condition, you need to tell your dentist before you come for your appointment,” says Martin Hogan, DDS, division director of dentistry at Loyola University Medical Center. “Depending on the illness, you may need to be premedicated with antibiotics to prevent infection.”

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Use of Air Conditioners Increases Nighttime Temperatures, Escalates Demand for Air Conditioning

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An Arizona State University research team found that releasing excess heat from air conditioners running during the night resulted in higher outside temperatures, worsening the urban heat island effect and increasing cooling demands.

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New Kidney Allocation Policy Could Improve the Success of Transplantations in the U.S.

• Simulation models predict that a newly approved kidney allocation policy will lead to an average 7.0% increase in median patient life-years per transplant and an average 2.8% increase in median allograft years of life. • The policy may also improve access to transplantation for highly sensitized candidates but reduce access for older patients.

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