Below are some of the latest articles that have been added to the Chemistry news channel on Newswise.
Researchers at UC Santa Cruz working to develop novel RNA-based medicines are teaming up with a new group of collaborators—players of the online game Eterna. The
Strokes are a leading cause of morbidity and mortality in the United States, as well as around the world. Various environmental and biological factors are known to affect the risks and outcomes of strokes.
A new study from the University of Sheffield has found clear evidence of socioeconomic disparities in operation rates and survival after surgery for dangerous abdominal aortic aneurysm.
Interdisciplinary research highlighted lipid-protein interaction as a new avenue for oncology drug development, demonstrating its functionality by designing small molecule-based inhibitors to target acute myeloid leukemia.
Measurement of plasma D-dimer levels – a test more commonly used to detect blood-clotting disorders – can provide useful information when making the difficult diagnosis of periprosthetic joint infection (PJI), reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
A first-of-its-kind study finds a natural coconut sugar may help reduce the risk of cardiovascular disease by improving blood vessel health and managing high blood pressure. The study is published ahead of print in the Journal of Applied Physiology.
A study of adolescents aged 11-16 in London has found long-term exposure to PM2.5 is associated with higher blood pressure, with stronger associations seen in girls.
Acute myeloid leukemia (AML) is an aggressive form of cancer that originates in the bone marrow, rapidly spreads to the blood and can quickly cause death if not treated promptly. Despite recent therapeutic advances, it continues to be associated with poor outcomes in the majority of patients with this disease.
The study focused on consumers impacted by sickle cell disease
Scientists investigating the causes of lymphoedema have made a major discovery, revealing that lymphatic vessels can produce red and white blood cells.
Johns Hopkins Medicine researchers have further documented an association between a substantially higher risk of maternal morbidity and mortality among those with the inherited blood disorder sickle cell disease (SCD) compared to those without it. Their analysis, using a large national administrative database with records for pregnant people with SCD, found the maternal mortality rate was 26 times greater than the national average. This figure has not improved since the last time this population was assessed.
Know your numbers? A Penn State Health cardiologist says a lipid panel can help you stave off a heart attack.
Below are some of the latest articles that have been added to the Surgery and the Transplantation channels on Newswise, a free source for journalists.
A University of Maryland School of Medicine (UMSOM) physician-scientist will head a new federally-funded research program to develop and test a whole blood product, storable at room temperature, that can be used to transfuse wounded soldiers in the field within 30 minutes of injury, potentially saving thousands of lives.
UNC-Chapel Hill scientists and colleagues provide indirect evidence for the existence of a distinct latent reservoir of CD4+ T cells in the central nervous system, by analyzing rebound virus in the cerebral spinal fluid during the period when people had just stopped taking ART.
Having levels of potassium that are too high or too low can be fatal. A new mathematical model sheds light on the often mysterious ways the body regulates this important electrolyte.
A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has breathed new life into an existing drug — combatting a type of blood cancer called T-cell acute lymphoblastic leukaemia, or T-ALL. The drug, called PIK-75, was initially discovered over a decade ago but was dismissed in favour of newer ones. Now, it has made a comeback that deems it unmissable — the researchers established that the drug could block not just one but two crucial cancer-causing pathways of T-ALL, enabling them to develop new treatments that could effectively stem the disease.
Patients with myelofibrosis had clinically significant improvement in disease-related symptoms, including anemia and spleen enlargement, when treated with the targeted therapy momelotinib, according to results from the international Phase III MOMENTUM trial led by researchers at The University of Texas MD Anderson Cancer Center.
People with an additional X or Y chromosome—a genetic condition known as supernumerary sex chromosome aneuploidy—have an increased risk of developing blood clots known as venous thromboembolism (VTE), a Geisinger study found.
Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs).
University of Maryland School of Medicine’s researchers have discovered that a certain type of cell that sits on top of the brain’s smallest blood vessels senses when their brain region needs energy. When glucose levels are low, these cells signal blood vessels to dilate, increasing the blood flow regionally and allowing more energy to fuel that part of the brain.
Sepsis can cause dangerously low blood pressure, which is typically treated with intravenous (IV) fluids and/or a vasopressor, a drug that causes constriction of the blood vessels. Whether treatment of sepsis-induced low pressure should primarily be treated with IV fluids or vasopressors has been debated for decades with no clear answer.
Many cardiovascular diseases, such as atherosclerosis, or ‘hardening of the arteries,’ correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels.
The next frontier of continuous health monitoring could be skin deep.
Nearly half a million people missed out on starting medication to lower their blood pressure during the Covid-19 pandemic, according to research supported by the British Heart Foundation (BHF) Data Science Centre at Health Data Research UK published today in Nature Medicine [1].
New UCLA-led research suggests that antiretroviral drugs called TAF and TDF directly reduce energy production by mitochondria, structures inside cells that generate the power that cells use to function. Both drugs led to reduced cellular oxygen consumption rates, a measure of the ability of the mitochondria to produce energy, compared with controls.
Patients hospitalized with fractures typically receive an injectable blood thinner, low-molecular-weight heparin, to prevent life-threatening blood clots.
Frequent visits to urban green spaces, such as parks and community gardens in Finland, rather than the amount, or views of them from home, may be linked to lower use of certain prescription meds, suggests research published online in Occupational & Environmental Medicine.
The researchers screened a library of drugs using a mouse endothelial cell line to identify pathways that are involved in the regulation of Robo4 and found that two competitive SMAD signaling pathways appear to regulate Robo4 expression. When the researchers treated LPS-injected mice with a drug that inhibits ALK1-SMAD signaling, they observed increased Robo4 expression, decreased vascular permeability, and reduced mortality.
Doctors at Queen Mary University of London and Barts Hospital, and Cambridge University Hospital, have led research using a new type of CT scan to light up tiny nodules in a hormone gland and cure high blood pressure by their removal. The nodules are discovered in one-in-twenty people with high blood pressure.
Promising results from an ongoing clinical trial a three-drug treatment may improve survival in patients with newly diagnosed multiple myeloma who have undergone preliminary treatment followed by a stem cell transplant.
CAR T cell therapy may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts.
School garden-based interventions can improve metabolic parameters such as blood sugar and cholesterol in children, according to a new study from UTHealth Houston.
Doctors from RUDN, in collaboration with the Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, evaluated a fresh approach to diagnose the preclinical predictors of arterial hypertension.
A newly published study from York University sheds light on the biological underpinnings in sex differences in obesity-related disease, with researchers observing “striking” differences in the cells that build blood vessels in the fatty tissue of male versus female mice.
Dr. Scott E. Smith, Section Chief of Hematology and Medical Director of the Bone Marrow Transplant Program at Loyola University Medical Center, is available today to discuss the non-Hodgkin's Lymphoma diagnosis of 33-year-old Chicago White Sox pitcher Liam Hendriks.
A group of international researchers is calling for revised guidelines to help improve access to hepatitis B treatment in Africa.
Scientists from St. Jude Children’s Research Hospital performed the largest study yet examining drug sensitivity in childhood acute lymphoblastic leukemia across genomic subtypes and its association with treatment response.
Still in the giving spirit as the new year begins? Consider giving blood.
Researchers at Washington University School of Medicine in St. Louis have identified an important transition point in the shift from chronic to aggressive leukemia.
A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.
In cancer patients with neutropenic fever, delaying antibiotic treatment past 60 minutes from the time of fever detection does not reduce the short-term chance of survival, according to a study in the American Journal of Medical Quality. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Clinical scientists with UC Davis and University of Cincinnati perform first-of-its-kind analysis showing a clear difference in cost-effectiveness of medication types for life-threatening condition
In a new study evaluating the Mediterranean diet and adverse pregnancy outcomes, investigators from the Smidt Heart Institute at Cedars-Sinai found that women who conceived while adhering to the anti-inflammatory diet had a significantly lower risk of developing preeclampsia during pregnancy.
Nerve cells need a lot of energy and oxygen. They receive both through the blood. This is why nerve tissue is usually crisscrossed by a large number of blood vessels.
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