Controversial Arrhythmia Drug Provides Only Modest Efficacy and No Clear Safety Benefits
Cedars-SinaiIn a rigorous new review of the antiarrhythmic drug dronedarone (Multaq), researchers at the Cedars-Sinai Heart Institute conclude that the controversial drug is only modestly effective and has no clear safety benefits. The review, to be published in the April 23 issue of the Journal of the American College of Cardiology, assessed data on dronedarone submitted during the drug's FDA approval process and determined that dronedarone is 50 percent less effective than amiodarone (Cordarone), a frequently used treatment for atrial fibrillation, a common type of heart rhythm disorder.