In cinema and science fiction, one small change in the past can have major, sometimes life-changing effects in the future. Using a series of snapshots, researchers recently captured such so-called “butterfly effects” in heart muscle cell development, and say this new view into the sequence of gene expression activity may lead to better understanding disease risk.
In a new study, aimed at using stem cells for hair growth, Columbia researchers have created a way to grow human hair in a dish, which could open up hair restoration surgery to more people, including women, and improve the way pharmaceutical companies search for new hair growth drugs.
Researchers at the University of Michigan Rogel Cancer Center and U-M College of Engineering have found that breast cancer cells that swallow up nearby stem cells take on some of their properties, enhancing their ability to invade other tissues throughout the body and seed secondary tumors, a process known as metastasis.
In a new study, published on June 25, 2019, in the journal eLife, the researchers report that higher levels of doublets can be found in people with severe cases of tuberculosis or dengue fever.
A study of thousands of patients’ health records found that those who were prescribed cholesterol-lowering statins had at least double the risk of developing type 2 diabetes. The detailed analysis of health records and other data from patients in a private insurance plan in the Midwest provides a real-world picture of how efforts to reduce heart disease may be contributing to another major medical concern.
Inspired by ideas from the physics of phase transitions and polymer physics, researchers at UC San Diego set out to determine the organization of DNA inside the nucleus of a living cell. Their findings suggest that the phase state of the genomic DNA is “just right”—a gel poised at the phase boundary between gel and sol, the solid-liquid phase transition.
Zillionaires like Amazon founder Jeff Bezos who see the 'colonisation' of space as an answer to the Earth's ever threatened resources will be reassured to learn that human sperm retains its complete viability within the different gravitational conditions found in outer space.
Tissue-resident memory T cells (TRMs) are known to help the body fight infection, but they are also key tumor fighters. A new study reveals that these cells are unique in their ability to seek out and kill tumor cells without suffering from the common phenomenon of T cell “exhaustion.”
SOFIE Inc. (SOFIE), a Theranostics company, is pleased to announce an exclusive global license with University Clinic Heidelberg (UKHD) for a class of molecular targeted diagnostics
Scientists have made the first observations of proteins assembling themselves into crystals, one molecule at a time, in a living cell. The method they used to watch this happen – an extremely high-res form of molecular moviemaking – could shed light on other important biological processes and help develop nanoscale technologies inspired by nature.
Researchers identify how a Chlamydia-produced protein helps bacterial compartments fuse together, thus increasing pathogenicity.
• A restrictive approach to blood cell transfusions in patients undergoing cardiopulmonary bypass surgery led to fewer transfusions than a more liberal approach, without any increased risk of acute kidney injury. • The results were consistent in patients with and without chronic kidney disease before surgery.
Scientists from University of North Carolina Lineberger Comprehensive Cancer Center have discovered a method for creating radioactive tracers used in PET imaging.
Researchers found that stem cells can commit to a cell fate far more rapidly than anticipated.
To heal hearts after heart attack, UNC School of Medicine researchers developed a stable, reproducible, minimalistic platform to reprogram human fibroblast cells in scar tissue into functional cardiomyocytes, the cells of healthy heart tissue.
Rather than relying on optics, the microscopy system offers a chemically encoded way to map biomolecules’ relative positions.
Investigators at Rutgers Cancer Institute of New Jersey have developed a computational method that uncovers clinically relevant gene expression patterns in large cohorts of breast cancer patients. This method, which is applicable to the analysis of all cancers, can robustly describe molecular processes that are associated with tumor subtypes and can identify predictive markers of response to treatment or disease recurrence.
June 19 is World Sickle Cell Awareness Day. Scientists at Cincinnati Children's have recently made three important steps forward in helping people with sickle cell in the U.S. and in sub-Saharan Africa live longer, better lives.
Transitions are a hallmark of life, and so there is a transition during early development when an embryo undergoes biochemical changes, switching from being controlled by maternal molecules to being governed by its own genome. For the first time, researchers have found in an embryo that activation of its genome does not happen all at once, instead it follows a specific pattern controlled primarily by the various sizes of its cells.
Bad news, Jurassic Park fans--the odds of scientists cloning a dinosaur from ancient DNA are pretty much zero.
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