Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical Center researchers showed in a new study.
A new UCLA Health study found certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson’s disease.
In the first year after the sudden removal of a requirement that prescribers get special permission to prescribe medication for opioid addiction, a study finds more prescribers started providing it, but the number of patients receiving it didn't rise very much.
Immigrants to Canada who have spent a greater proportion of their lives in Canada have a greater risk of developing multiple sclerosis (MS) than people who have spent a smaller proportion of their lives there, according to a study published in the April 24, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that an increased proportion of life in Canada causes MS; it only shows an association.
People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology® Clinical Practice, an official journal of the American Academy of Neurology. The acid-reducing drugs include proton pump inhibitors such as omeprazole and esomeprazole, histamine H2-receptor antagonists, or H2 blockers, such as cimetidine and famotidine, and antacid supplements.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Investigators in the Smidt Heart Institute at Cedars-Sinai and colleagues report that women with Type 2 diabetes diagnosed with hypertension before age 50 may benefit from intensive blood pressure treatment.
Paul Barnes, the Marguerite Scribante Professor of Piano in the Glenn Korff School of Music, will be performing a special program of composer Philip Glass’s works inside “Greenpoint,” a sculpture by Richard Serra on the University of Nebraska–Lincoln’s City Campus at noon, May 1. The performance is free and open to the public.
Franziska Roesner, a University of Washington associate professor, has two papers coming out in May looking at TikTok’s algorithm and its effects on users.
At a time when health resources are at a premium and need to be wisely allocated, health professionals must find points within men’s lives when it makes the most sense to intervene and advocate for preventive care for promoting better health outcomes.
In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC). Published in Clinical Cancer Research, the findings illustrate the potential of siRNA for cancer therapy.
In Applied Physics Letters, researchers use laser treatments to transform ordinary cork into a powerful tool for treating oil spills. They tested variations of a fast-pulsing laser treatment, closely examining the nanoscopic structural changes and measuring the ratio of oxygen and carbon in the material, changes in the angles with which water and oil contact the surface, and the material’s light wave absorption, reflection, and emission across the spectrum to determine its durability after multiple cycles of warming and cooling.
Commonly referred to as “magic mushrooms,” psilocybin is a promising alternative treatment for people with medication-resistant depression and anxiety.
To celebrate Hubble’s 34th launch anniversary, NASA released the telescope’s new observation of the Little Dumbbell Nebula. Also known as Messier 76, or M76, it is composed of a ring, seen edge-on as the central bar structure, where a central red giant star burned out, and two lobes of gas and dust that are on either opening of the ring.
Patients have lower rates of mortality and hospital readmissions when treated by female physicians, with female patients benefitting more than their male counterparts.
Infants and children 5 years old and younger experienced only “modest” delays in developmental milestones due to the COVID-19 pandemic disruptions and restrictions, a study led by Johns Hopkins Children’s Center finds.
America is going the wrong way when it comes to prescribing antibiotics, with 1 in 4 prescriptions going to patients who have conditions that the drugs won’t touch, a new study finds.
While most parents of preschool and elementary aged children strive to give their children a balanced, nutritional diet, some of their strategies to promote healthy eating may backfire, a national poll suggests.
Low-to-moderate drinking may not be protective against certain health conditions, and “safe” alcohol use guidelines may be substantially off base. These are among the implications of a review of studies that use a novel research method.
Auburn University’s McCrary Institute for Cyber and Critical Infrastructure Security was awarded a $10 million Department of Energy grant in partnership with Oak Ridge National Laboratory to create a pilot regional cybersecurity research and operations center to protect the electric power grid against cyberattacks.
Certain drinking behaviors beyond just the quantity of alcohol consumed may predict the likelihood a person will experience an alcohol-induced blackout, a condition where someone is conscious and engaging with their surroundings but will be unable to remember some or any of what occurred.
April is Oral Cancer Awareness Month, and the American Association of Nurse Anesthesiology (AANA) reminds the public that the best prevention of oral health issues is early detection. However, patients also need to be aware of the critical importance of ensuring access to safe anesthesia care during oral cancer treatments including surgery.
Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based test that addresses a major problem in prostate cancer: how to separate the slow-growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment.
A new typing model simulates the typing process instead of just predicting words
Astronomers and volunteer citizen scientists used Hubble's unique capabilities to identify a largely unseen population of very small asteroids. The treasure hunt required perusing 37,000 archived Hubble images spanning 19 years. The payoff? Finding 1,701 asteroid trails, with 1,031 of the asteroids previously uncatalogued. About 400 of these uncatalogued asteroids are smaller than 1 kilometer.
The warming climate shifts the dynamics of tundra environments and makes them release trapped carbon, according to a new study published in Nature. These changes could transform tundras from carbon sinks into a carbon source, exacerbating the effects of climate change.
The new institute, which honors the memory of the noted researcher in superconducting and clean energy, will advance research on a wide array of scientific challenges.
Cedars-Sinai investigators have discovered how brain cells responsible for working memory—the type required to remember a phone number long enough to dial it—coordinate intentional focus and short-term storage of information.
The harder your brain works at your job, the less likely you may be to have memory and thinking problems later in life, according to a new study published in the April 17, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A detailed reconstruction of climate during the most recent ice age, when a large swath of North America was covered in ice, provides information on the relationship between CO2 and global temperature. Results show that while most future warming estimates remain unchanged, the absolute worst-case scenario is unlikely.
A new study led by the University of Portsmouth has used 30 years of data from the Office for National Statistics to distinguish between how much people spent on essential and non-essential goods and services.
The protein Asc-1 serves as the gateway (either for entry or exit) for fundamental amino acids involved in cognitive processes. A new study now unveils its structure and mechanism of action.
Nearly everyone with Down syndrome will eventually develop Alzheimer's disease. Researchers at Washington University School of Medicine in St. Louis have discovered that Alzheimer’s disease starts earlier and moves faster in people with Down syndrome.
In a new study, a Johns Hopkins Medicine-led research team reports that social stress during adolescence in female mice later results in prolonged elevation of the hormone cortisol after they give birth.
By merging the findings of several diet-brain studies, researchers hope to better understand the association between dietary intake and cognitive decline or impairment.
Aalto University researchers adapt a novel force measurement technique to uncover the previously unidentified physics at play at the thin air-film gap between water droplets and superhydrophobic surfaces.
An FDA advisory committee (ODAC) voted 12-0 today in favor of a major shift in how the agency evaluates new treatments for multiple myeloma. If approved by the FDA, the result will be faster approval of new treatments for multiple myeloma.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Argonne National Laboratory and RIKEN, leaders in high performance computing in the U.S. and Japan, have established a cooperative relationship in support of artificial intelligence computing projects.
The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts. That’s still the case, for the most part, but, Johns Hopkins Medicine researchers, studying nerve cells grown in the lab and mice, say that the proteasome’s role may go well beyond that.
While asleep, the area of birds’ brains dedicated to singing remains active, triggering vocal muscles without producing sound. In Chaos from AIP Publishing, researchers translate the muscle activity to synthesize the songs of avian dreams. Reproducing distinctive bird calls provides a window into the contents of the bird’s dreams.
Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide.
Storing chemicals in a garage at home may associate with an increased risk of ALS, a study finds. This comes as research has found that exposure to environmental toxins, such as pesticides and volatile organic compounds, are also linked to ALS development. Researchers call the buildup of exposures of the lifetime the ALS exposome.
Treatment for lung condition could help patients with sickle cell disease control complications from hypertension and kidney damage
Meandering ocean currents play an important role in the melting of Antarctic ice shelves, threatening a significant rise in sea levels.
A new study by a University of Portsmouth astrophysicist sheds light on the relationship between the Milky Way and the Egyptian sky-goddess Nut.
A changing climate may be linked to growing death and disability from stroke in regions around the world, according to a study published in the April 10, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Humans aren’t the only living beings who find a singing voice attractive in the opposite sex – songbirds do too. For about a third of the approximately 4,000 songbird species that sing only one song, the features that make these tunes alluring to a potential mate have been a long-standing mystery.
A Johns Hopkins Medicine-led research team has added to evidence that a chemical found naturally in cannabis (also known as marijuana) can — in the right amounts — lessen the anxiety-inducing effects of tetrahydrocannabinol (THC), the primary psychoactive sister chemical found in cannabis.
A new analysis by researchers at UCLA Health found that mortality rates of middle-aged Black Americans caused by the “deaths of despair” -- suicide, drug overdose and alcoholic liver disease – surpassed the rate of white Americans in 2022.
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