This is the first visual function for incident AMD in older adults with normal macular health and early AMD. Older adults with delayed dark adaptation have a heightened risk for developing AMD within the next few years. Vision in bright light was known to be relatively preserved late into the disease. Night vision is affected much earlier.
A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration (AMD).
Researchers at MIND Institute at UC Davis and Rush University Medical Center have found that mavoglurant, an experimental drug known as an mGluR5 negative modulator, can positively modify a key characteristic behavior in individuals with fragile X syndrome (FXS).
Using a novel patient-specific stem cell-based therapy, researchers at the National Eye Institute (NEI) prevented blindness in animal models of geographic atrophy, the advanced “dry” form of age-related macular degeneration (AMD), which is a leading cause of vision loss among people age 65 and older. The protocols established by the animal study, published January 16 in Science Translational Medicine (STM), set the stage for a first-in-human clinical trial testing the therapy in people with geographic atrophy, for which there is currently no treatment.
Following a nationwide search, Mass. Eye and Ear named Aalok Agarwala, MD, MBA, as Chief Medical Officer, and Kathrin Bourdeu, MD, PhD, as Chief of Anesthesia.
There are new medications and procedures to treat glaucoma. Getting regular eye exams is the first step in protecting your eyes from glaucoma and other eye disorders that can lead to vision loss.
Glaucoma is a group of eye diseases that gradually steal sight without warning. Although the most common forms primarily affect the middle-aged and the elderly, glaucoma can affect people of all ages.
Three days of events uniting research, industry, and philanthropy to prevent vision loss from glaucoma and speed the cure.
Launched in 2007, this annual benefit showcases the visionaries and catalysts who share Glaucoma Research Foundation's mission to cure glaucoma and restore vision through innovative research.
Tracking technology used by retailers serves another purpose at Kellogg Eye Center: to track and reduce patient wait times and enhance time spent at the doctor’s office.
A molecule derived from a type of primrose could prove to be a potent inhibitor of metastatic growth for a rare and aggressive cancer.
A study from researchers at Indiana University has found that CBD -- a major chemical component in marijuana -- appears to increase pressure inside the eye of mice, suggesting the use of the substance in the treatment of glaucoma may actually worsen the condition.
New appointments will enhance pediatric care, research, and education
A new treatment for patients with a form of congenital retinal blindness has shown success in improving vision, according to results published today in led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.
A new study in Ophthalmology Retina – a journal of the American Academy of Ophthalmology – shows that BB and pellet guns do blind children every year. And, the number of eye injuries related to such nonpowder guns are increasing at an alarming rate. Another study published earlier this year showed an increase of almost 170 percent over the last 23 years.
Researchers at Stanford University, Palo Alto, California, have created a noninvasive technology that detects when nerve cells fire based on changes in shape. The method could be used to observe nerve activity in light-accessible parts of the body, such as the eye, which would allow physicians to quantitatively monitor visual function at the cellular level.
What is Normal-tension glaucoma? Also called low-tension or normal-pressure glaucoma, normal-tension glaucoma (NTG) is a condition in which the optic nerve is damaged without eye pressure exceeding the average range (usually between 12-21mm Hg).
What is Normal-tension glaucoma? Also called low-tension or normal-pressure glaucoma, normal-tension glaucoma (NTG) is a condition in which the optic nerve is damaged without eye pressure exceeding the average range (usually between 12-21mm Hg).
A new study by a Cornell University marketing expert upends that assumption. And it offers new insights into optimal resource allocation at health care nonprofits not only in low- and middle-income countries but also in higher-income countries.
The National Eye Institute (NEI) awarded $25,000 to a team led by Wei Liu, Ph.D., Albert Einstein College of Medicine, for demonstrating progress toward the development of a living model of the human retina, the light-sensitive tissue at the back of the eye. The prize money was awarded for the first of two phases of the NEI 3-D Retina Organoid Challenge 2020 (3-D ROC 2020), a national initiative to generate human retina organoids from stem cells. NEI is part of the National Institutes of Health.
While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms. Instead, tumors arise when a mutation happens in a particular cell type that is uniquely sensitive to it. Identifying such cancer cells of origin is essential to properly target cancer.
Jessica Martindale’s perfect vision was quickly tested after her infant son inadvertently scratched her cornea. Thankfully, physicians at UAB Callahan Eye Hospital were there to help.
Researchers working to understand the biochemistry of cataract formation have made a surprising finding: A protein that was long believed to be inert actually has an important chemical function that protects the lens of the eye from cataract formation.
It is easy to remember steps to prevent the body from getting cold, but what can be done to protect the eyes when cold weather hits?
Allen Taylor, a senior scientist and director of the Laboratory for Nutrition and Vision Research at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, named a Fellow of the American Association for the Advancement of Science (AAAS).
Mayo Clinic’s Nuclear Medicine Division on Mayo Clinic's Arizona, Florida and Minnesota campuses significantly increased services provided to clinical and research patients in 2018. The division debuted a new therapeutic-diagnostic, or “thera-nostic,” practice, joined major research trials, and advanced radiotracer production capabilities.
Physicians at Massachusetts Eye and Ear have, for the first time, induced a sense of smell in humans by using electrodes in the nose to stimulate nerves in the olfactory bulb, a structure in the brain where smell information from the nose is processed and sent to deeper regions of brain. Reporting online today in International Forum of Allergy & Rhinology, the research team describes their results, which provide a proof of concept for efforts to develop implant technology to return the sense of smell to those who have lost it.
Scientists at the National Eye Institute (NEI) have found that neurons in the superior colliculus, an ancient midbrain structure found in all vertebrates, are key players in allowing us to detect visual objects and events.
By the time symptoms of sporadic Creutzfeldt-Jakob disease (sCJD) are typically discovered, death is looming and inevitable. In a new study, researchers at University of California San Diego School of Medicine with colleagues at the National Institutes of Health and UC San Francisco, report finding tell-tale evidence of the condition’s infectious agent in the eyes of deceased sCJD patients, making the eye a potential source for both early CJD detection and prevention of disease transmission.
New research show that calcified nodules in the eye increase the risk for progression to advanced AMD.
Dry Eye Syndrome Slows Reading Rate, Study Suggests 11/15/2018 AddThis Sharing Buttons Share to Facebook Share to TwitterShare to EmailShare to PrintShare to More Slow reading rate and significantly disrupt day to day tasks that require visual concentration for long periods of time . Johns Hopkins researchers report that chronic dry eye, a condition in which natural tears fail to adequately lubricate the eyes, can slow reading rate and significantly disrupt day to day tasks that require visual concentration for long periods of time. Credit: iStock Johns Hopkins researchers report that chronic dry eye, a condition in which natural tears fail to adequately lubricate the eyes, can slow reading rate and significantly disrupt day to day tasks that require visual concentration for long periods of time.
Currently, all therapy for glaucoma is directed at lowering eye pressure, but the fundamental problem in glaucoma is the degeneration of the optic nerve fibers necessary for vision.
In August of 2017, millions peered through protective eyewear at the solar eclipse—the first total eclipse visible in the continental United States in nearly 40 years. During the event, researchers from the Cornell Lab of Ornithology and the University of Oxford watched radar to observe the behavior of birds and insects.
By combining two imaging modalities—adaptive optics and angiography—investigators at the National Eye Institute (NEI) can see live neurons, epithelial cells, and blood vessels deep in the eye’s light-sensing retina. Resolving these tissues and cells in the outermost region of the retina in such unprecedented detail promises to transform the detection and treatment of diseases such as age-related macular degeneration (AMD), a leading cause of blindness among the elderly.
• New research show that calcified nodules in the eye increase the risk for progression to advanced AMD more than six times • There is an urgent need to identify early events that might lead to visual loss in people so interventions can be made • Global burden of AMD is estimated to cost be over 300 billion worldwide
Cataracts surgery is recognized as a medical marvel, but even years after the procedure, some patients may experience "secondary cataracts." Melinda Duncan and her UD team have focused on scare tissue that forms after surgery to address the problem.
Zebrafish eye injected with retinoblastoma tumor cells (green) form a mass in areas close to the injection site. A few of these tumor cells move outside the eye. Credit: Johns Hopkins Medicine By comparing genetic sequences in the eye tumors of children whose cancers spread with tumors that didn’t spread, Johns Hopkins Medicine researchers report new evidence that a domino effect in cells is responsible for the cancer spreading. Their experiments suggest that blocking part of the chain of events — which they successfully accomplished in zebra fish and human cells — stops the growth and spread of the eye tumor cells.
Scientists at Johns Hopkins Medicine say they have identified what may be an ancient light-sensing mechanism in modern mouse retinal cells.
Shortly after birth when the world is a blur, babies may be learning to identify patterns. According to a new study funded by the National Eye Institute (NEI), the initial phase of blurry vision may be fundamental to the development of normal visual processing.
A new era in the management of glaucoma is ushered in by a landmark study published in the Journal of Glaucoma, Official Journal of the World Glaucoma Association. Patients with primary open angle glaucoma (POAG) showed significant improvements of both ocular and general health after participating in a program of mindful meditation focused on breathing compared to the control group that did not partake.
The grants are designed to foster cross-disciplinary cooperation among leading basic, translational and clinical neuroscientists in an effort to propel discoveries from laboratory to clinic.
Researchers from the University of California, Irvine School of Medicine, have discovered that neurons located in the vision centers of the brains of blind rats functioned normally following fetal retina cell transplants, indicating the successful restoration of vision. The research was published today in JNeurosci, the Journal of Neuroscience.
Rutgers researchers discover new technique to improve vestibular function, which assists with balance
Dr. Okihide Hikosaka, senior investigator at the National Eye Institute (NEI) Laboratory of Sensorimotor Research, is a recipient of the 2018 Gruber Prize in Neuroscience.
Fourth annual Forum will be held Feb. 28-March 2 in Dallas, Texas.
A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.
An Oct. 31 event at Children’s Hospital of Philadelphia highlights the Philadelphia's role in manufacturing 21st century products: tools for precision medicine. The hospital's new Clinical Manufacturing Facility will produce clinical-grade vectors to deliver cellular and gene therapy for difficult-to-treat diseases.
A new study led by researchers at Massachusetts Eye and Ear found that good performance on a piloting task was associated with lower vestibular thresholds, which represent stronger ability to sense and perceive information about motion, balance and spatial orientation. Published online today in the Journal of Neurophysiology, the findings suggest that astronauts or pilots with higher vestibular thresholds are more likely to become disoriented during flight, especially in situations when gravity is less than that on Earth – such as on the Moon.
A team of ophthalmologists went looking for scientific evidence in support of commercially available “cell therapy” for eye diseases. Not only did they find virtually none; they instead discovered a growing number of patients are being irreparably harmed by unapproved cell therapies.
A study examining the diagnoses generated by WebMD Symptom Checker showed the online tool was correct only 26 percent of the time. And the recommendation for the top diagnosis was often inappropriate, at times recommending self-care at home instead of going to the emergency room.
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