Trotz jahrzehntelanger wissenschaftlicher Untersuchungen haben die Erforscher der Alzheimer-Krankheit deren Ursache und Behandlungsmethoden noch nicht klären können. Zu verstehen, was den drei verschiedenen Subtypen der Krankheit zugrunde liegt, gilt als vielversprechender neuer Forschungsansatz.
Pese a décadas de escrutinio científico, a los investigadores sobre la enfermedad de Alzheimer todavía les queda por resolver su causa y tratamiento. No obstante, se cree que al entender lo que subyace bajo los tres subtipos distintos, las nuevas investigaciones se enrumbarán por un camino esperanzador.
How well eight-year-olds score on a test of thinking skills may be a predictor of how they will perform on tests of thinking and memory skills when they are 70 years old, according to a study published in the October 30, 2019, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that education level and socioeconomic status were also predictors of thinking and memory performance. Socioeconomic status was determined by people’s occupation at age 53.
A new study from Columbia University found that a higher level of education protected against cognitive decline in black people with a gene linked to Alzheimer’s disease.
The human brain can recognise a familiar song within 100 to 300 milliseconds, highlighting the deep hold favourite tunes have on our memory, a UCL study finds.
Although there’s no cure for dementia, there are therapies that impact how people can continue to function well and lead good lives.
Despite decades of scientific scrutiny, Alzheimer's disease researchers have yet to work out its cause or treatment. Understanding what underlies its three distinct subtypes is thought to be a promising new research avenue. In a new study in JAMA Neurology, a team of neuroscientists at Mayo Clinic in Florida led by Melissa Murray, Ph.D., examined a key region of the brain and found that patterns of Alzheimer's-related damage differed by subtype and age of onset.
Early retirement can accelerate cognitive decline among the elderly, according to research conducted by faculty at Binghamton University, State University of New York.
The way people walk is an indicator of how much their brains, as well as their bodies, are aging. Scientists reporting in a special supplement to the Journal of Alzheimer's Disease (JAD) say that gait disorders
A new study of 3,000 people in Wisconsin aged 21 and older with Down syndrome, published today [Monday, Oct. 28, 2019] in JAMA Neurology by researchers at the University of Wisconsin–Madison, shows that by age 55, three in five will be diagnosed with Alzheimer’s disease or a similar neurodegenerative condition. Meanwhile, people without Down syndrome are rarely diagnosed with dementia before age 65.
What can reading 26,000 books tell researchers about how language environment affects language behavior? Brendan T. Johns, an assistant professor of communicative disorders and sciences at UB has published a computational modeling study that suggests our experience and interaction with specific learning environments, like the characteristics of what we read, leads to differences in language behavior that were once attributed to differences in cognition.
Prior to an Alzheimer’s diagnosis, a person in the early stages of the disease faces a heightened risk of adverse financial outcomes — a likely consequence of compromised decision making when managing money, in addition to exploitation and fraud by others.
Investigators at the University of Alabama at Birmingham and Stanford University want to learn more about silent strokes and their role in brain health, cognitive decline and dementia.
This two-part event on Alzheimer’s disease will focus largely on a novel approach involving autophagy, a cellular mechanism that only recently has been linked to the disease’s development. During the first part, a workshop, scholars, students, and professionals will exchange their ideas and research topics scientifically. In the second part, a panel discussion, experts will discuss and explain key results to the public.
Prof. Dr. Christian Behl is a Professor of Pathobiochemistry and Chair and Director of the Institute of Pathobiochemistry at the University Medical Center of the Johannes Gutenberg University Mainz in Germany. His research expertise is on neurodegeneration, the cause of a number of diseases linked to old age like Alzheimer’s, Parkinson’s and ALS, and on ways of preventing novel concepts based on basic molecular mechanisms, for instance autophagy.
Since its inception in 1995, the mission for A Woman’s Journey has remained the same: to empower women to make the right health care decisions for their families and themselves.
A UCLA-led study finds that, with the use of MRI scans, it is possible to distinguish between memory loss caused by Alzheimer’s disease and traumatic brain injury.
A new study from Washington University School of Medicine in St. Louis indicates that people with dementia – whose parents also had dementia – develop symptoms an average of six years earlier than their parents.
Older people who experienced more hospitalizations and also had more Alzheimer’s pathology in their brain experienced the fastest rates of cognitive decline, according to study results published in the October 15 online issue of the Annals of Neurology.
Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson’s and Alzheimer’s diseases, and improves cognitive and motor behavior.
The memory of specific episodes is the base of autobiographical memory, but we do not know how the brain structures the experience to remember it in the long run.
A new multisite study funded by the National Institute on Aging will examine whether co-occurring Alzheimer’s disease and stage 4 breast or prostate cancer alters pain perception, potentially leading to undertreated cancer pain.
Value in Health, the official journal of ISPOR, announced today the publication of an analysis showing that direct medical costs are the major cost driver of Alzheimer’s disease care in Thailand, a finding distinct from other countries across the world.
Rush is part of national study to test effects of lifestyle intervention on older adults at risk for dementia.
A new study examining the role that star-shaped brain cells called astrocytes play in Huntington’s disease has identified a potential strategy that may halt the disease and repair some of the damage it causes.
The National Institutes of Health has awarded a five-year, multi-investigator research grant expected to total more than $63 million to Mayo Clinic and the University of California, San Francisco (UCSF), to advance treatments for frontotemporal lobar degeneration (FTLD).
A new Stony Brook University-led study, to be published in PNAS, provides a biophysical model that reveals how damage accumulates in proteins with age and is a trigger to death. The finding opens a door to a better understanding of the molecular origins of age-related neurodegenerative diseases.
In a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individual patients with frontotemporal dementia (FTD)
At the American Neurological Association's 2019 Annual Meeting, Kim Campbell, Alzheimer’s disease (AD) advocate and widow of Grammy Hall of Fame and Award-winning music legend Glen Campbell, recounted both the toll that Alzheimer's disease took on her husband and their family, and the musical talent that sustained him.
Researchers at the University of Toronto (U of T) specializing in language variation and change have identified a specific relationship between an individual's use of language
In a media roundtable at 11 a.m. U.S. Central on Tuesday, October 15, leading neuroscientists will summarize key science being presented at the American Neurological Association’s 2019 Annual Meeting (ANA2019). Reporters may attend in person or dial in.
Everybody knows sleep is good for your body. It may be good for your mind, too. That’s what scientists at Wake Forest School of Medicine will attempt to determine thanks to a $5.3 million grant from the National Institute on Aging, part of the National Institutes of Health.
Using sex-specific scores on memory tests may change the diagnosis for 20 percent of those currently diagnosed with mild cognitive impairment (MCI), with possibly more women and fewer men being diagnosed with MCI, according to a new study published online in the journal Neurology.
A study from Washington University School of Medicine in St. Louis has found that microglia drive neurodegeneration in diseases, including Alzheimer's disease, that are linked to tau protein. Targeting microglia may help treat such diseases.
Using sex-specific scores on memory tests may change who gets diagnosed with mild cognitive impairment (MCI) by 20 percent, with possibly more women and fewer men being diagnosed, according to a study published in the October 9, 2019, online issue of Neurology®
Study finds when verbal memory test cut-offs were tailored to patient sex, more female patients and fewer male patients were considered to have amnesic mild cognitive impairment. This could change the way aMCI diagnoses are determined and make it easier to catch the condition in its early stages.
Georgetown University Medical Center, a Lewy Body Dementia (LBD) Association Research Center of Excellence, is now offering three clinical trials to study new treatments for LBD, a disease often confused with Parkinson’s and Alzheimer’s disease.
Alzheimer’s disease advocate and widow of Grammy Hall of Fame and Award-winning music legend Glen Campbell; and ANA President David Holtzman, MD, ANA President, Professor and Chairman of the Department of Neurology at the Washington University School of Medicine. The keynote address for the American Neurological Association’s 2019 Annual Meeting. Ms. Campbell will offer the caregiver perspective during the Presidential Symposium on “Dominantly Inherited and Late-Onset Alzheimer’s Disease” chaired by Dr. Holtzman.
People with Alzheimer's disease who used antipsychotic drugs had a higher number of accumulated hospital days than people with Alzheimer's disease who did not use antipsychotics
The responsibility of being a caregiver for a loved one is admirable and gratifying.
The Sanders-Brown Center on Aging at the University of Kentucky has received a five-year, $2.8 million grant to underwrite preclinical efficacy studies of a potential new treatment for dementia.
Researchers assessed the ability of older adults with advanced dementia to participate in non-pharmacological interventions and compared chair yoga with chair-based exercise and music therapy. Results showed that participants with moderate-to-severe dementia could safely adhere to non-pharmacological interventions; more than 97 percent fully engaged in each session. The chair yoga group reported a higher quality of life score, including physical condition, mood, functional abilities, interpersonal relationships, and ability to participate in meaningful activities.
The IU-led center is one of only two multi-institution teams in the nation selected as part of a new federal program intended to improve, diversify and reinvigorate the Alzheimer's disease drug development pipeline.
A National Institute on Aging grant will support Penn’s Center for Neurodegenerative Disease Research to study the underlying genetic connections between Alzheimer's Disease, Parkinson's Disease, and Dementia.
Telomeres are protective caps at the ends of chromosomes that become shorter with each cell division. If they become so short that the genes they protect could be damaged, the cell stops dividing and renewing. Consequently, the cell is increasingly unable to perform its functions. This mechanism is one of the ways in which we age.
University of Warwick researchers have developed a superior method to describe the very earliest effects that Alzheimer’s Disease proteins have on the properties of brain cells.
A University of California, Irvine-led team of scientists has discovered how newly identified neural circuits in the brain’s hippocampal formation play a critical role in object-location learning and memory.
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