New research from UAB identifies an epigenetic cause for why patients with temporal lobe epilepsy tend to have memory loss, and suggests a potential way to reverse that loss. The findings indicate the discovery may have implications for many other memory disorders.
Researchers at the University of Georgia have used a gene editing tool known as CRISPR/Cas to modify the genome of a tree species for the first time. Their research opens the door to more rapid and reliable gene editing of plants.
The article describes the current and future roles of the laboratory professional as genomic sequencing analysis becomes an ever more increasingly important tool in diagnostic medicine.
Leveraging a novel system designed to examine the double-strand DNA breaks that occur as a consequence of gene amplification during DNA replication, Whitehead Institute scientists are bringing new clarity to the causes of such genomic damage. Moreover, because errors arising during DNA replication and gene amplification result in chromosomal abnormalities often found in malignant cells, these new findings may bolster our understandings of certain drivers of cancer progression.
What is it with cheating? Cheaters seem to have an immediate advantage over cooperators, but do they have an evolutionary advantage? A study published in Current Biology suggests the benefits of cheating change with its prevalence,in a population. Cheaters may succeed, for example, only when they are rare, and fail when they become so numerous they push out cooperators.
Trending news releases with the most views in a single day. Topics include: aging & genetics, cancer, treatment for kidney disease, healthcare & wellbeing, environment, welcoming new leaders.
Lung cancer, the world’s deadliest cancer, can be apparently successfully treated, only to return. And when it does so, it’s often resistant to the drugs that worked the first time. Now, a team led by Prof. Yosef Yarden has devised a novel three-pronged strategy that, in mice, kept lung cancer cells from developing resistance in the first place.
A study of the rapid evolution of the insulin-signaling molecular network that regulates growth, reproduction, metabolism and aging lays important groundwork for future studies.
University of Adelaide researchers have discovered cerebral palsy has an even stronger genetic cause than previously thought, leading them to call for an end to unnecessary caesareans and arbitrary litigation against obstetric staff.
A rare eye disorder marked by color blindness, light sensitivity, and other vision problems can result from a newly discovered gene mutation identified by an international research team, including scientists from Columbia University Medical Center (CUMC). The findings, which were published today in the online edition of Nature Genetics, could lead to new, targeted treatments for this form of color blindness.
Trending news releases with the most views in a single day. Topics include: neurology, cancer, immunotherapy, Alan Alda present science award, genetics, vision, lung cancer, prostate cancer, environmental health.
People with achromatopsia, an inherited eye disorder, see the world literally in black and white. Worse yet, their extreme sensitivity to light makes them nearly blind in bright sunlight. Now, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health System have identified a previously unknown gene mutation that underlies this disorder.
A team of scientists from Berkeley Lab, JGI and UC Berkeley, simplified and sped up genome assembly, reducing a months-long process to mere minutes. This was primarily achieved by “parallelizing” the code to harness the processing power of supercomputers.
In a report of a proof-of-principle study of patients with colon and other cancers for whom standard therapies failed, researchers at the Johns Hopkins Kimmel Cancer Center say that mistakes in so-called mismatch repair genes, first identified by Johns Hopkins and other scientists two decades ago, may accurately predict who will respond to certain immunotherapy drugs known as PD-1 inhibitors.
Scientists at the University at Buffalo have identified the mechanisms behind a genetic mutation that produces certain autistic behaviors in mice, as well as therapeutic strategies to restore normal behaviors.
Trending news releases with the most views in a single day. Topics include: income inequality, climate change, genetics, cancer, precision medicine, medical imaging, schizophrenia, research funding, molecular biology and skin cancer.
A landmark clinical study in the Lancet provides convincing evidence that a frequently overlooked therapy for genetically-caused emphysema is effective and slows the progression of lung disease.
Researchers have uncovered a new molecular mechanism - a function of the NONO protein - whereby cells protect their genome from the detrimental effect of UV radiation and govern DNA replication in cellular mitosis. A recent study investigates what happens when this molecular mechanism malfunctions.
Researchers at the Stowers Institute have shown that a molecule called elongin A assists with transcription.
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