Researchers at UT Southwestern Medical Center and in Australia have shown that a drug currently in testing shows potential to cure malaria in a single dose and offers promise as a preventive treatment as well.
Researchers at the University of Georgia have developed new tools to study and genetically manipulate cryptosporidium. Their discoveries, published in the journal Nature, will ultimately help researchers find new treatments and vaccines for cryptosporidium, a major cause of disease and death in children under 2 years old.
Researchers from the University of Georgia have determined that various freshwater sources in Georgia, such as rivers and lakes, could feature levels of salmonella that pose a risk to humans. The study is featured in the July edition of PLOS One.
Viruses, not bacteria, are the most commonly detected respiratory pathogens in U.S. adults hospitalized with pneumonia, according to a New England Journal of Medicine study released today and conducted by researchers at Centers for Disease Control and Prevention (CDC) and hospitals in Chicago and Nashville, including Vanderbilt University Medical Center.
An examination of state vaccination requirements for adolescents finds that the human papillomavirus (HPV) vaccine is currently required in only two states, many fewer than another vaccine associated with sexual transmission (hepatitis B) and another primarily recommended for adolescents (meningococcal conjugate), according to a study in the July 14 issue of JAMA.
Infections with one of the most troublesome and least understood antibiotic-resistant “superbugs” are increasing. But now scientists at Washington University School of Medicine in St. Louis have shown the bacteria, A. baumannii, can naturally relinquish its defenses against antibiotics.
Research with human tissue and cells suggests that genetic variations, in addition to failure to comply with treatment regimens, may account for some failures of an anti-HIV drug to treat and prevent HIV infection.
The percentage of U.S. Air Force recruits with detectable immunity to measles, mumps and rubella was lower than found in previous nationwide samples and may be low enough for outbreaks to occur, according to a study, "Measles, Mumps, and Rubella Titers in Air Force Recruits: Below Herd Immunity Thresholds?" released July 7, in the American Journal of Preventive Medicine.
Scientists from the Florida campus of The Scripps Research Institute have shown that, unlike other antiretroviral therapies, a natural compound called Cortistatin A establishes a near-permanent state of latency and greatly diminishing the HIV virus’ capacity for reactivation.
Vanderbilt University Medical Center’s James Crowe, M.D., Ann Scott Carell Professor and director of the Vanderbilt Vaccine Center, and his team are reporting the first large panel of antibody treatments against the chikungunya virus in the current issue of Cell Host and Microbe.
Infectious diseases such as hepatitis C and some of the world’s deadliest superbugs—C. difficile and MRSA among them—could soon be detected much earlier by a unique diagnostic test, designed to easily and quickly identify dangerous pathogens.
Other topics include memories and protein, physics and gas mileage, agriculture and food safety, vaccine for Dengue, retinoblastoma proteins in cancer progression, and more.
Over the same time period that multiple outbreaks of measles and whooping cough made headlines around the country, parents’ views on vaccines became more favorable.
Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus.
The McMaster team recruited 75 patients with a flare up of their ulcerative colitis and randomized them to fecal transplant therapy given as an enema derived from stool donated by an anonymous healthy donor, and placebo.
Mosquitoes transmit malaria, West Nile virus and chikungunya virus. Monitoring these insects is critical to understanding when and where to control them and lessen the risk of human disease. Insect experts the world over use carbon dioxide, the same gas that humans exhale, to attract blood-feeding bugs to traps, so they can measure their abundance, test them for diseases and make decisions about whether or not to control them.
HIV, or human immunodeficiency virus, is the retrovirus that leads to acquired immunodeficiency syndrome or AIDS. Globally, about 35 million people are living with HIV, which constantly adapts and mutates creating challenges for researchers. Now, scientists at the University of Missouri are gaining a clearer idea of what a key protein in HIV looks like, which will help explain its vital role in the virus’ life cycle. Armed with this clearer image of the protein, researchers hope to gain a better understanding of how the body can combat the virus with the ultimate aim of producing new and more effective antiviral drugs.
A mosquito in western South Dakota has tested positive for West Nile virus—the next step is transmission to humans. Two South Dakota State University researchers will help mosquito control officials use mosquito surveillance and environmental data to target West Nile virus through a three-year NASA grant.