The disease systemic lupus erythematosus (SLE) — marked by the attack on joints, skin, and kidneys by the body’s immune system — is linked to an abnormal mix of bacteria in the gut. This is according to a new study led by scientists at NYU School of Medicine.
Collaborative research by The Wistar Institute and Moffitt Cancer Center has demonstrated that BRAF targeted therapies render resistant melanoma more sensitive to the attack of killer T cells.
The American Academy of Dermatology and the National Psoriasis Foundation's two new psoriasis guidelines, which address comorbidities and biologics, were published online in the Journal of the American Academy of Dermatology on Feb. 13.
Henry Ford Cancer Institute oral cancer patient Marlene Calverley, a minimally-invasive sentinel node biopsy meant having three instead of 30-60 lymph nodes removed, and a two-inch scar instead of a five-to-six-inch scar. It also meant no neck drains, no physical therapy, and a decreased risk of complications.
In the spirit of Valentine’s Day, dermatologists from the American Academy of Dermatology are advising the public about a simple yet important self-care routine: nail grooming. Not only do short, well-manicured nails look great, they say, they are also less likely to harbor dirt and bacteria, which can lead to an infection. In addition, the right nail clipping technique can help prevent common issues like hangnails and ingrown toenails.
New insights on circumventing a key obstacle on the road to anti-scarring treatment have been published by Maksim Plikus, an associate professor in development and cell biology at the UCI School of Biological Sciences and colleagues in Nature Communications. The research team discovered that the natural scar-free skin repair process relies partially on assistance from circulating blood cells. The results point the way toward possible treatments for scar-free wound healing that target the body’s own blood cells.
Tungiasis, a tropical disease associated with poverty, is caused by the penetration of female sand fleas into a person’s skin, usually in their toes or feet. This week in PLOS Neglected Tropical Diseases, researchers report five cases of severe tungiasis to illustrate how the disease may develop into a life-threatening condition.
The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy.
Identifying molecular pathways that boost the immune response to tumor neoantigens opens up new ways to develop and amplify cancer immunotherapy.
Researchers have pinpointed how fibrosis develops in butterfly syndrome patients. The discovery points to a potential treatment for the debilitating complication.
Injection of a genetically modified virus that induces the body’s own immune cells to attack metastatic melanoma effectively treated almost 40 percent of patients with tumors that could not be surgically removed.
If a patient has private insurance, doctors can get prior approval to prescribe a drug “off-label” to make sure the medication will be covered, but these lists are incomplete, outdated, and frequently in conflict with each other.
Skin colour is one of the most visible and variable traits among humans and scientists have always been curious about how this variation evolved. Now, a study of diverse Latin American populations led by UCL geneticists has identified new genetic variations associated with skin colour.
A Ludwig Cancer Research study has uncovered a cellular mechanism by which melanomas that fail to respond to checkpoint blockade may be made susceptible to such immunotherapies. Led by Ping-Chih Ho of the Lausanne Branch of the Ludwig Institute for Cancer Research and reported in the current issue of Nature Immunology, the study also identifies an existing diabetes drug that could be used to accomplish that feat.
A study by researchers from Sweden and Hungary shows that white, painted stripes on the body protect skin from insect bites. It is the first time researchers have successfully shown that body-painting has this effect. Among indigenous peoples who wear body-paint, the markings thus provide a certain protection against insect-borne diseases.
The use of antibiotics to treat inflammatory skin conditions like acne and rosacea is decreasing over time, but there has been an increase in prescriptions associated with dermatologic surgical procedures.
Researchers at University of Utah Health conducted a state-by-state analysis to understand the geographic disparities for patients diagnosed with melanoma. The results of their study suggest that lower survival is associated with more practicing physicians in a region and higher population of Caucasians.
MD Anderson researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers.
Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held belief about cancer metabolism. The findings could bring about a better understanding of many cancers' metabolic needs and lead to the development of more effective therapies for squamous cell skin cancer and other forms of epithelial cancer.
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