Many rare disorders are caused by gene mutation. Yet until now the underlying genetic cause of more common conditions has evaded scientists. New research finds that six common diseases arise from DNA changes located outside genes. The study shows that multiple DNA changes, or variants, work in concert to affect genes, leading to autoimmune diseases.
Engineered immune cells, called CARTmeso cells, designed to direct antitumor immune responses toward tumors that carry a protein called mesothelin, showed antitumor activity in two patients with advanced cancers that had not responded to prior treatments, according to a study published in Cancer Immunology Research, a journal of the American Association for Cancer Research.
Children can eat a favorite fast-food meal and still cut calories, according to a recent Cornell University study of a popular fast-food meal. In 2012, McDonald’s made changes to its Happy Meal to improve the nutritional quality of the popular children’s meal. In a recent study, Cornell University’s Food and Brand Lab researchers Brian Wansink and Andrew Hanks analyzed more than 230,0000 transactions from 30 representative McDonald’s restaurants to document whether the change led to more healthful meal selections.
Study shows that eating plenty of tomatoes and tomato-based products, even for a short period, helped protect at-risk postmenopausal women
Scientists have developed a new set of molecular tools for controlling the production of (poly)phenols, plant compounds important for flavors, human health, and biofuels.
Freeing the immune system to track down and kill tumors is helping a widening circle of patients.
UT Southwestern neuroscience researchers have identified a gene that controls the response to cocaine by comparing closely related strains of mice often used to study addiction and behavior patterns.
A new study identifies an unexpected molecular link between liver cancer, cellular stress, and risk factors for developing this cancer – obesity, alcoholism, and viral hepatitis.
The face you critiqued in the mirror this morning was sculpted before you were born by a transient population of cells called neural crest cells. Those cells spring from neural tissue of the brain and embryonic spinal cord and travel throughout the body, where they morph into highly specialized bone structures, cartilage, connective tissue, and nerve cells.
• Investigators have discovered a cocktail of chemicals which, when added to stem cells in a precise order, turns on genes found in kidney cells in the same order that they turn on during embryonic kidney development. • The kidney cells continued to behave like kidney cells when transplanted into adult or embryonic mouse kidneys.
• Among women on chronic dialysis, sexual inactivity is common, with the most frequently described reasons being lack of interest in sex and lack of a partner. Rarely is sexual difficulty reported as a reason for lack of interest • Most women on chronic dialysis—including those lacking interest in sex—are satisfied with their sex lives.
A new study has uncovered an unprecedented example of horizontal gene transfer in a South Pacific shrub that is considered to be the sole survivor of one of the two oldest lineages of flowering plants.
This multi-topic issue includes research topics with relevance for Veterans and non-Veterans alike. Reaching Veterans and finding unique ways to overcome barriers to care has become a greater priority for the VA. Two guest editorials in this issue look at ways this is happening, including setting up services on college campuses and using horses in rehabilitation to improve the quality of life for our Veterans.
Most people with dementia who live at home have multiple unmet health and welfare needs, any number of which could jeopardize their ability to remain home for as long as they desire, new Johns Hopkins research suggests.
Steven C. George, MD, PhD, has been named chair of the Department of Biomedical Engineering at Washington University in St. Louis, effective July 1, 2014. George is professor of biomedical engineering and of chemical engineering & materials science at the University of California, Irvine. In addition, he is the Edwards Lifesciences Professor and director of the Edwards Lifesciences Center for Advanced Cardiovascular Technology.
The world’s first and largest group medical practice and one of the nation’s premier volunteer service organizations of professional African American women are joining forces to eradicate health disparities among communities of color in the United States. Mayo Clinic and The Links, Incorporated have established a formal collaboration that aims to develop a more diverse health care workforce. The joint initiative ranges from raising health awareness in the African American community to facilitating scientific research -- with a special focus on cardiovascular disease, cancer, organ transplantation and obesity. The collaboration stems from one patient’s experience.
Every year, patients have "a bucketful of excuses" for not getting a flu vaccine. Dr. Jennifer Caudle, of RowanSOM discusses and dispels the seven most common myths and misconceptions she hears about the vaccine.
In two separate clinical trials, researchers at Albert Einstein College of Medicine of Yeshiva University have found that periodic meetings with a lactation consultant encourages women traditionally resistant to breastfeeding to do so, at least for a few months—long enough for mother and child to gain health benefits.
Despite recent advances in prevention and treatment of most vision loss attributed to diabetes, a new study shows that fewer than half of Americans with damage to their eyes from diabetes are aware of the link between the disease and visual impairment, and only six in 10 had their eyes fully examined in the year leading up to the study.
A new issue of the American Journal of Public Health captures latest research for improving birth outcomes with topics ranging from disparities to breastfeeding.
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