Japan’s population is rapidly aging. As a result, new challenges have emerged as an increased number of elderly people, many of whom live in isolated parts of the country, need medical and nursing care despite inadequate medical resources.
Researchers at UC San Diego provide new insights into the pathology of limbic predominate age-related TDP-43 encephalopathy, which mimics Alzheimer’s, making it very difficult to identify in living patients.
Alzheimer’s disease (AD) is the fifth leading cause of death in adults over 65 years old. While many potential treatments for the neurodegenerative disease focus on developing drugs to target key culprits, a relatively new approach aims to more directly treat the brain.
What are the keys to “successful” or optimal aging? A new study followed more than 7000 middle aged and older Canadians for approximately three years to identify the factors linked to well-being as we age.
For decades, doctors and scientists have known that exercise is important for older adults — it can lower risk for cardiac issues, strengthen bones, improve mood and have other benefits. Likewise, mindfulness training reduces stress, and stress can be bad for the brain, so many have thought that exercise and/or mindfulness training might improve brain function.
New research suggests that former professional football players may face accelerated aging, despite past research showing they have life spans similar or longer than the general population
In the new study, retired football players reported shorter health spans — defined as years free of disease – than men in the general population
Two age-related diseases — arthritis and dementia — were found more commonly among former football players, compared with men of the same age in the general population
Additionally, hypertension and diabetes were more common among younger former players, those ages 25 to 29, compared with same-age men from the general population.
The results warrant further study to define the biochemical, cellular, and physiologic mechanisms behind premature aging in former football players
UT Southwestern researchers have discovered a new form of progeria, a rare premature-aging syndrome, in a man from Malaysia and traced its cause to a novel gene mutation.
Their older parents need care. Their kids are still under 18. And they probably have a job, too. They’re the “sandwich generation” – a longtime nickname for the mostly female, mostly middle-aged group of Americans who serve as caregivers for both older and younger family members at once. A new study estimates there are at least 2.5 million of them, while giving a detailed view into who they are, and which older adults rely on them.
Researchers at Tufts University have completed the first study examining levels of vitamin D in brain tissue, specifically in adults who suffered from varying rates of cognitive decline. They found that members of this group with higher levels of vitamin D in their brains had better cognitive function.
Businesses are more often turning to older workers to fill employment gaps and a new University of Iowa study finds countries that spend more on health care don’t see a significant difference in sick days taken by younger and older workers.
Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies led by UCL researchers.
With flu cases on the rise, geriatric specialists at UT Southwestern Medical Center say vaccinations are particularly important this year for people 65 and older who are more at risk from complications than other age groups.
A study is the first to use a large range of instruments/ tools and include older adults from many ethnic groups to determine factors affecting their physical activity. Results showed that age, education, social network, pain and depression accounted for a statistically significant proportion of unique variance in physical activity in this diverse older population living independently. Those who reported lower physical activity tended to be older, have less years of education and reported lower social engagement, networking, resilience, mental health, self-health rating, and higher levels of depression, anxiety, pain, and body mass index compared to the moderate to high physical activity groups.
In a study using a first-of-its kind mouse model of aging that mimics breast cancer development in estrogen receptor-positive post-menopausal women, investigators at Georgetown Lombardi Comprehensive Cancer Center and colleagues have determined that over-expression, or switching on of the Esr1 gene, could lead to elevated risk of developing estrogen receptor-positive breast cancer in older women.
A pilot, “look-back” study of information about 106 patients with “wet” age-related macular degeneration (AMD) treated at the Wilmer Eye Institute at Johns Hopkins Medicine has revealed that nearly half of patients treated with aflibercept could safely stop eye injection therapy after one year without further vision loss.
Caregiving robots would be transformative for people with disabilities and their caretakers, but few research groups are working in this space. A new robotic simulation platform developed by Cornell researchers may help more people enter the field.
The Pfizer-BioNTech COVID-19 vaccine limits transmission, hospitalization, and death from COVID-19 even among patients infected by variants of the virus, but the effectiveness of antibodies it generates diminishes as patients get older, according to a study by UT Southwestern researchers.
Molecular biologist Yu Xin (Will) Wang, Ph.D., has joined Sanford Burnham Prebys as an assistant professor in the Development, Aging, and Regeneration Program to uncover the ways muscle, nerve and immune cells work together to overcome disease.
People who eat or drink more foods with antioxidant flavonols, which are found in several fruits and vegetables as well as tea and wine, may have a slower rate of memory decline, according to a study published in the November 22, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The UC San Diego Sanford Stem Cell Institute leads its first space launch, sending stem cells into space aboard the International Space Station. The NASA-partnered study will take advantage of the microgravity environment of space to study accelerated aging in stem cells.
New research from the University of California, Irvine, suggests aging is an important component of retinal ganglion cell death in glaucoma, and that novel pathways can be targeted when designing new treatments for glaucoma patients.
The Penn Artificial Intelligence and Technology Collaboratory for Healthy Aging (PennAITech) – made up of Penn’s School of Nursing, the Perelman School of Medicine, and other departments across the University – focuses on identifying developing, evaluating, commercializing, and disseminating innovative technology and artificial intelligence methods/software to support aging. It’s made possible through a grant from the National Institute on Aging, a part of the National Institutes of Health. In its first year, and through a competitive national grant review process, twelve applicants from academia, industry, and clinical practice across the United States have been selected for funding.
A team of geriatricians at Mount Sinai’s Brookdale Department of Geriatrics and Palliative Medicine has been awarded $1.25 million from the Health Resources and Services Administration and the Keith Haring Foundation to expand Mount Sinai’s interdisciplinary model of care for older patients living with HIV.
American transplant centers as well as organ procurement organizations, the groups responsible for recovering organs from deceased donors in the United States, were less likely to accept or select organs from donors who were 70 years old when they died compared to those who were 69, new research found.
As a clinical social worker, Natasha Mosby has counseled family members on both sides of the spectrum: the caretakers and their aging parents. Both groups want to understand how to navigate their reversal of roles as they progress into this new chapter of their lives.
Adopting some of the strategies behind successfully treating the childhood disease spinal muscular atrophy may enable development of therapies to curb the muscle decline that accompanies aging, new research suggests.
Muscle weakness marked by grip strength is associated with accelerated biological age, a new study suggests. Results were found using "age acceleration clocks" based on DNA methylation, a process that provides a molecular biomarker and estimator of the pace of aging. Researchers say this suggests potential to adopt use of grip strength as a way to screen individuals for future risk of functional decline, chronic disease and early mortality.
A year of aerobic exercise training reduced impedance (effective resistance to blood flow) in the brain blood vessels of older adults, according to a new study.
Rejuvenating the immune cells that live in tissues surrounding the brain improves fluid flow and waste clearance from the brain — and may help treat or even prevent neurodegenerative diseases such as Alzheimer’s and Parkinson’s, according to a study by researchers at Washington University School of Medicine in St. Louis.
Sex differences in the aging brain may offer an enticing clue for researching more effective neuroprotective treatments, according to a new treatment development strategy laid out by UCLA researchers.
More than half of people over 50 say they’ve helped at least one person over 65 take care of their health, personal hygiene, home or finances in the past two years. Nearly all say they get something positive out of the experience.
Drug companies and university-based teams are working urgently to find and test new medications that could prevent or slow the decline of brain function in older adults. But a new study suggests they’ll need to work harder to find volunteers for their clinical trials.
Donna Wilcock, Ph.D., of the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) was awarded a $1.7 million National Institutes of Health grant for her lab’s exploration of adverse effects of two new Alzheimer’s disease drugs — aducanumab and lecanemab — which have been shown to slow the progression of cognitive decline.
A multidisciplinary effort to improve care for older patients who arrive at the emergency room with a hip fracture has decreased the time before they have surgery, shortened hospital stays, and resulted in better follow-up care
UT Southwestern Medical Center has received exemplar status by the Nurses Improving Care for Healthsystem Elders (NICHE) – an international designation that indicates a hospital's commitment to achieving the highest level of geriatric care excellence.
Mount Sinai researchers have catalogued thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.
A new study from Washington University School of Medicine in St. Louis indicates that as patients age, Huntington's disease gradually impairs autophagy, which eliminates waste from cells. This housekeeping is significant because a buildup of waste in a specific kind of neuron leads to such cells’ untimely deaths. The researchers also showed that enhancing the autophagy pathway in such neurons that were created from skin cells of Huntington’s patients protects those cells from dying.
Now, new research from the University of South Australia gives strong evidence that vitamin D deficiency is associated with premature death, prompting calls for people to follow healthy vitamin D level guidelines.
In recognition of National Healthy Skin Month in November, board-certified dermatologists are providing their top tips for caring for your skin, hair, and nails.