A worldwide research effort is underway for finding a treatment option for hyperphagia, the most common genetic cause of life-threatening childhood obesity.
Brain imaging of pathological tau-protein "tangles" reliably predicts the location of future brain atrophy in Alzheimer's patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and Aging Center.
For sick or prematurely born babies spending their first days of life in a hospital’s neonatal intensive care unit (NICU), the soothing voice and gentle touch of a loving parent can have a tremendous impact toward a positive outcome — that is, unless mom or dad’s visit leaves the infant with something extra: a dangerous bacterial infection.
Yale Cancer Center (YCC) announces the launch of the Center for Community Engagement and Health Equity (CEHE). Building on YCC’s longstanding commitment to high-quality, expert, and patient-centered cancer care, screening, and prevention across the state of Connecticut, the new Center is dedicated to ensuring cancer health equity and improving outcomes with an emphasis on traditionally underserved neighborhoods.
An innovative approach to analyzing the medical scans of patients in clinical trials could help ensure the accuracy of trial results while reducing the workload for busy oncologists, according to a new study by researchers at the University of Michigan Rogel Cancer Center.
Proton therapy leads to significantly lower risk of side effects severe enough to lead to unplanned hospitalizations for cancer patients when compared with traditional radiation, while cure rates between the two groups are almost identical
Pregnant women living with HIV don’t always receive antiretroviral medications recommended for use in pregnancy, according to a recent study published in Jama Network Open this week. Ann & Robert H. Lurie Children's Hospital of Chicago’s researchers collaborated in the multi-site Surveillance Monitoring for ART Toxicities (SMARTT) study of the Pediatric HIV/AIDS Cohort Study (PHACS) network.
Saint Louis University’s Enrico Di Cera, M.D., has been named a Fellow of the American Association for the Advancement of Science (AAAS) for his distinguished contributions to science.
GB Sciences, Inc. (OTCQB: GBLX) announced significant preclinical results for their Parkinson's disease ("PD") formulations from the midterm report for their preclinical study being performed by Dr. Lee Ellis of the National Research Council (NRC) in Halifax, Nova Scotia, CANADA.
A GPS map to guide neural navigation devices developed by a Case Western Reserve University cancer researcher has shown 90% accuracy in pinpointing brain tumors and will soon be tested in real time with patients at Cleveland Clinic under a three-year, $600,000 V Foundation grant.
A Mayo Clinic study involving 5,540 patients with metastatic colorectal cancer finds that maintenance chemotherapy after initial treatment is more beneficial for patients whose disease is under control, compared with more aggressive treatment.
Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way to move precision immunotherapy forward by using genomics to inform immunotherapy for multiple myeloma, a blood cancer, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research, in December.
The U.S. Food & Drug Administration (FDA) granted accelerated approval to the drug enfortumab vedotin (EV) to treat adult patients with advanced urothelial or bladder cancer.
Tired of living with painful arthritic knees, 54-year-old Deborah Brown’s interest was piqued when she saw a recruitment flyer for a clinical trial on an innovative pain treatment at The University of Texas Health Science Center at Houston (UTHealth).
In the search for an Alzheimer’s cure, the scientific community has focused on drugs to lessen the buildup of amyloid protein in the brain. But new research published today in Science Translational Medicine finds that targeting tau pathology shows promise.The discovery came by looking at what could make worms resistant to pathological tau protein. That’s when researchers discovered the role of the MSUT2 gene. The latest study applied to mice as well. And held true in autopsy samples of Alzheimer's patients.
A new study published in Journal of Vascular and Interventional Radiology details the first study of its kind in the U.S. to examine the use of genicular artery embolization (GAE) for extended treatment of knee pain caused by osteoarthritis (OA). Principal investigator of the study, Ari Isaacson, MD, clinical associate professor of vascular and interventional radiology in the UNC School of Medicine, says the results are positive.
The European Society for Medical Oncology (ESMO) has named Thomas Gajewski, MD, PhD, Abbvie Foundation Professor of Cancer Immunotherapy in the Ben May Department for Cancer Research and Professor of Pathology and Medicine at the University of Chicago, as the recipient of the 2019 ESMO Immuno-Oncology Award for his groundbreaking work uncovering why some patients are resistant to immunotherapy and how to restore the anti-cancer immune response.
St. Jude Children’s Research Hospital announced today that Elizabeth Fox, M.D., has been named senior vice president of clinical trials research.
A drug purified and developed from the sap of a tree in the Amazon rainforest is now being studied for the treatment of chronic idiopathic diarrhea in non-HIV patients at The University of Texas Health Science Center at Houston (UTHealth) as part of a two-year pilot study.
A clinical trial investigating the repurposed cancer drug nilotinib in people with Parkinson’s disease finds that it is reasonably safe and well tolerated. Researchers also report finding an increase in dopamine, the chemical lost as a result of neuronal destruction, and a decrease in neurotoxic proteins in the brain among study participants. Finally, they say nilotinib, a tyrosine kinase inhibitor, potentially halts motor and non-motor decline.
A new study led by Washington University School of Medicine in St. Louis suggests there is a link between bacteria that live in the upper airway and the severity of asthma symptoms among children with mild to moderate asthma.
Clinical Research Pathways, an Atlanta-based non-profit, announces a grant to Wellstar Health System designed to increase diversity in oncology-related clinical trials
Hackensack Meridian Health Jersey Shore University Medical Center achieved re-accreditation from the National Accreditation Program for Breast Centers (NAPBC), a program administered by the American College of Surgeons.
As células-tronco derivadas da gordura de um paciente oferecem um passo para melhorar - e não apenas estabilizar - a função motora e sensorial de pessoas com lesões na medula espinhal, de acordo com pesquisas anteriores da Mayo Clinic.
تقدم الخلايا الجذعية المأخوذة من دهون المريض خطوة نحو تحسين - وليس مجرد استقرار - في الحركة والوظائف الحسية لمن يعانون من إصابات في الحبل النخاعي، وذلك وفقًا لبحث أولي أجرته Mayo Clinic.
Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli (ETEC), and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens.
Mayo Clinic and W. L. Gore & Associates Inc., a global materials science company, have formed a joint venture to advance the development of implantable cell therapies to treat debilitating conditions with no cure. Avobis Bio will combine Mayo Clinic's clinical and cell expertise and Gore’s expertise in material sciences to address some of the most challenging medical issues.
The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after radiation therapy
New findings by Yale Cancer Center (YCC) and Smilow Cancer Hospital researchers show that as the use of the drug ibrutinib climbs in patients with chronic lymphocytic leukemia (CLL), so do the rates of patients who stop taking the drug.
Scientists using specialized beamlines at Argonne's Structural Biology Center (SBC), a facility for macromolecular crystallography at the Advanced Photon Source, derived insights that led to the discovery of a promising new drug for Ebola.
At an event Thursday at Rutgers, thought leaders from academia, health care, government and the pharmaceutical industry discussed the future of scientific and clinical trial innovation in the state, as a result of an innovative consortium between Rutgers University, Princeton University and the New Jersey Institute of Technology.
Approximately half of the patients were randomly assigned whole breast radiation, delivered once per day over three to five weeks. The other half received external beam APBI, considered to be the least invasive approach to partial breast irradiation, which was given twice a day over five to eight days. The study was long-term, with a median followup of 8.6 years.
Researchers from University of California San Diego School of Medicine and the Salk Institute for Biological Studies reported a form of intermittent fasting, called time-restricted eating, improved the health of study participants who had been diagnosed with metabolic syndrome.
UC San Diego launches new Center for Fluorescence-Guided Surgery. The center builds upon Roger Tsien’s legacy, delivering a new caliber of surgical precision to treat patients with tumors and disease of all types, identifying unhealthy tissues with a fluorescent glow.
The American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) released the 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease. It is the first criteria developed specifically for this recently recognized disease.
First patient enrolled at The University of Kansas Cancer Center in expansion cohort study characterizing the safety, pharmacokinetics and pharmacodynamics of fosciclopirox in bladder cancer patients
If you are thinking of buying a skin rejuvenation device as a holiday gift, think again.
One year after surpassing $500 million in research grant and award funding, University of Alabama at Birmingham faculty, staff and administration have hit another institutional milestone for the first time in its 50-year history — exceeding more than $600 million in research funding awards.
Long-term treatment with gabapentin, a commonly prescribed drug for nerve pain, could help restore upper limb function after a spinal cord injury, new research in mice suggests.
Along with the promise that CRISPR-Cas9 gene editing technology can offer new human therapies is the need to ensure its safety. A recent study showed that CRISPR-Cas9 did not produce off-target gene mutations in zebrafish. These results, published in Frontiers in Genetics, confirm previous data in animal models that the risk to the rest of the genome from gene editing is minimal.
Evidence from 13 randomized trials of the treatment of migraine in 4,222 patients and tens of thousands of patients in prevention of recurrent attacks supports the use of high dose aspirin from 900 to 1,300 milligrams to treat acute migraine as well as low dose daily aspirin from 81 to 325 milligrams to prevent recurrent attacks. Aspirin is available without a prescription, is inexpensive, and has a relatively favorable side effect profile compared to alternative more expensive medications.
Las células madre derivadas del propio tejido adiposo del paciente constituyen un paso adelante en el mejoramiento (no solo en la estabilización) de las funciones motoras y sensoriales después de una lesión de la médula espinal, informa uno de los primeros estudios sobre el tema realizado por Mayo Clinic.
Healthy Humming, LLC is pleased to announce positive topline data from a prospective outcomes study, which assessed the safety and efficacy of the SinuSonic, a nasal congestion treatment device that combines nasal acoustic vibration with oscillating expiratory pressure.
A study in Nature shows stem cell therapy helps hearts recover from a heart attack, although not for the biological reasons originally proposed two decades ago that today are the basis of ongoing clinical trials. The study reports that injecting living or even dead heart stem cells into the injured hearts of mice triggers an acute inflammatory process, which in turn generates a wound healing-like response to enhance the mechanical properties of the injured area.
Stem cells derived from a patient's own fat offer a step toward improving — not just stabilizing — motor and sensory function of people with spinal cord injuries, according to early research from Mayo Clinic.
A team from the Beaumont Research Institute believes low-dose radiation might be a promising treatment for Alzheimer’s disease. The researchers are now seeking patients with Alzheimer’s disease for the study.
Scientists at Oregon State University may have proven how much people love coffee, tea, chocolate, soda and energy drinks as they validated their new method for studying how different drugs interact in the body.
Mayo Clinic's Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome (HLHS) and Children's of Alabama announce their collaboration within a consortium to provide solutions for patients with hypoplastic left heart syndrome, a rare and complex form of congenital heart disease in which the left side of the heart is severely underdeveloped.
Doctors need better ways to detect and monitor heart disease, the leading cause of death in industrialized countries. Researchers have developed an improved optical imaging technique that found differences between potentially life-threatening coronary plaques and those posing less imminent danger for patients with coronary artery disease. Their method may give cardiologists additional data to identify patients at higher risk of future heart attacks and help them improve medical therapy.
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