The Institute of Human Virology (IHV) at the University of Maryland School of Medicine congratulates Treasurer Nancy Kopp on her five decades of public service, including since 2002, as the Maryland State Treasurer.
Patients with the blood cancer multiple myeloma often mount a poor antibody response to COVID-19 vaccines. Mount Sinai researchers have now discovered that these patients also have a weak response from a different part of the immune system, known as T cells. Their discovery was published in a research letter in Cancer Cell in October.
Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental biological mechanisms. By deciphering the cell migration mechanisms underlying the immune response, scientists from the University of Geneva (UNIGE), in Switzerland, and the Ludwigs-Maximilians University (LMU), in Germany, have shown that the activation of the immune system is modulated according to the time of day.
The severe outbreak of COVID-19 in Delhi, India, in 2021 showed not only that the Delta variant of SARS-CoV2 is extremely transmissible but that it can infect individuals previously infected by a different variant of the coronavirus, say a team of international scientists writing in Science.
Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.
ROCHESTER, Minn. — While people know their health affects their longevity and quality of life, many struggle to do even the small things that will help them live younger longer. Stephen Kopecky, M.D., a preventive cardiologist at Mayo Clinic, shares his insights on protecting overall health and boosting the immune system from his book, "Live Younger Longer: 6 Steps to Prevent Heart Disease, Cancer, Alzheimer's and More." Dr. Kopecky is a two-time cancer survivor.
A team of South Dakota State University chemistry researchers uncovered how cancer cells utilize a simple sugar residue to disguise themselves from the immune system. What they learned will help scientists develop more effective cancer therapeutics.
Researchers at Washington University School of Medicine in St. Louis have discovered that the viral protein NS1 from respiratory syncytial virus (RSV) alters the activity of immune genes, sabotaging the immune response to RSV infection.
A team at the Department for Pharmaceutical Sciences developed a therapy concept that could stop tumor growth.The immune system protects the body from cancer. To protect healthy body cells from its own immune system, they have developed a protective shield: the protein CD47 is a so called "don’t eat me" signal, which tells the immune cells to stand back.
Atopic diseases, which include eczema, allergic rhinitis, asthma, and food allergy, are closely linked to allergies against airborne particles, such as pollen, dust, mold, or animal dander, or foodstuffs like peanut, milk, soy, shellfish, or wheat.
The New York Stem Cell Foundation’s (NYSCF) 16th Annual Conference – held virtually on October 19-20 – convenes global leaders in stem cell research to present their latest progress towards new treatments and cures for the most devastating diseases and injuries in the world.
Multisystem inflammatory syndrome in children (MIS-C) is a serious condition associated with a recent COVID-19 infection.
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts. Current advances include promising clinical results for therapies targeting HER2, FGFR and TGF- β, discovering new drivers of lung cancer development, novel approaches to predict immune responses and overcome immunotherapy resistance, and a novel combination therapy for prostate cancer.
In a study published today in the American Journal of Transplantation, Johns Hopkins Medicine researchers say that children between the ages of 12 and 18 who have received solid organ transplants appear to mount a more robust immune response than their adult counterparts after a standard two-dose vaccination regimen against SARS-CoV-2, the virus that causes COVID-19.
Two new studies presented today at the 2021 AACC Annual Scientific Meeting & Clinical Lab Expo reveal how antibodies against the SARS-CoV-2 virus can vary among recipients of different COVID-19 vaccines and naturally infected individuals. The findings provide critical data about the immune response to COVID-19 vaccines that could inform future diagnostic research and vaccination efforts.
UChicago Medicine physician-scientists aimed to find out how the immune systems of children with a type of cancer called neuroblastoma respond to tumors. The answer to this question could help guide the treatment of pediatric patients.
The University of Kent’s School of Biosciences and the Institute of Medical Virology at Goethe-University, Frankfurt am Main, have identified a protein that may critically contribute to severe forms of COVID-19.
Scientists at La Jolla Institute for Immunology (LJI) have published a detailed map of where human antibodies bind to SARS-CoV-2, a map that was generated by a global collaboration comparing nearly all leading clinical candidates. The new research will guide the development of more effective COVID-19 antibody therapies and help scientists develop effective vaccines to address emerging viral variants.
Two UT Southwestern Medical Center researchers – a biochemist and a molecular biologist – are among 33 distinguished scientists nationwide named Howard Hughes Medical Institute (HHMI) Investigators.
A newly developed immunotherapy that simultaneously uses modified immune-fighting cells to home in on and attack two antigens, or foreign substances, on cancer cells was highly effective in mice implanted with human neuroblastoma tissue.
A unique type of tiny antibody produced by llamas could provide a new frontline treatment against Covid-19 that can be taken by patients as a simple nasal spray.
Women who receive COVID-19 mRNA vaccines during pregnancy pass high levels of antibodies to their babies, a new NYU Langone study finds.
Iowa State researchers affiliated with the Nanovaccine Institute have explained how a nanomaterial initiates antibody production by the immune system's B cells. The technique could be used to turn B cells into factories that provide antibodies for diagnostic tests or treatments.
ACAAI is having an in-person meeting this year to deliver the latest news in allergies, asthma, and immunology.
Today, the American College of Chest Physicians (CHEST), American Lung Association and American Thoracic Society released the following statement in response to the increase in COVID-19 cases and hospitalizations.
Here are seven amazing developments in the use of Focused Ultrasound from just the last three months, including: treating cancerous tumours, triggering the targeted release of medicine in the body, immunotherapy, and pain management. See more in the Focused Ultrasound Channel
A new therapeutic era has been ushered in with Adoptive Cell Immunotherapy, which uses patient-harvested T cells genetically engineered against tumor-specific targets.
At a time when incidence of Lyme disease is rising across the U.S., a study led by University of Kentucky College of Medicine researcher Brian Stevenson, Ph.D., may provide a significant impact in the fight against the disease. A new study will build upon Stevenson's three decades of research aimed at understanding Borrelia burgdorferi, the bacteria that causes Lyme disease.
Breathe in, breathe out. That’s how easy it is for SARS-CoV-2, the virus that causes COVID-19, to enter your nose.
Immunologists and geneticists at UT Southwestern Medical Center have discovered how vitamin A enters immune cells in the intestines – findings that could offer insight to treat digestive diseases and perhaps help improve the efficacy of some vaccines.
Antibodies and T cells play a critical role in protection from viral illness, however the exact role of T cell and antibody responses in SARS-CoV-2 infection is unclear. To better understand the immune abnormalities linked to critical illness and death in COVID-19 patients on ICU, researchers conducted a prospective observational study investigating the association of T cell and antibody responses with fatal outcome in severe COVID-19.
New research shows that Multiple Sclerosis (MS) patients undergoing anti-CD20 (aCD20) treatment – which depletes the B cells that contribute to the MS attacks – are able to mount robust T-cell responses to the mRNA COVID-19 vaccines, despite having a muted antibody response to the vaccines.
A family of proteins best known for their role in diminishing HIV infectivity may have the goods to outwit other emerging and re-emerging viruses, scientists have found.
In a new article published in the Journal of the National Cancer Institute, Moffitt Cancer Center researchers report that patients treated with immune checkpoint inhibitors have a higher self-reported quality of life than patients treated with other types of therapy.
An expert review by an international group of scientists, including some at the WHO and FDA, concludes that, even for the delta variant, vaccine efficacy against severe COVID is so high that booster doses for the general population are not appropriate at this stage in the pandemic.
MD Anderson and SNIPR BIOME have announced a strategic collaboration to advance next-generation CRISPR-based microbiome therapies to reduce immune-related side effects in patients treated with immune checkpoint inhibitors.
A research team has identified a potential cause of long-lasting symptoms experienced by COVID-19 patients, often referred to as long-haulers. The findings were published in the journal, The Public Library of Science ONE (PLOS ONE).
The presence of special immune system defense molecules, called autoimmune antibodies, has been strongly tied to how poorly people fare when hospitalized with COVID-19, a new study shows.
The gut microbiome can impact us in a variety of different ways, from our metabolism to our mood. Now, NIBIB-funded researchers are investigating if a fiber-based gel can restore beneficial microbes in the gut to enhance the efficacy of immune checkpoint inhibitors, a type of cancer immunotherapy treatment, in mice.
As students head back to school this fall, sports medicine physicians with Loyola Medicine say the risk of COVID-19 exposure among student athletes is low. As the Delta variant of COVID-19 continues to spread across the U.S., Nathaniel Jones, MD, a sports medicine physician for Loyola Medicine, emphasizes the importance of getting vaccinated.
A new analysis by a team of physician-researchers at Beth Israel Deaconess Medical Center (BIDMC) provides the first evidence that monoclonal antibodies were indeed underutilized in the first six months of FDA authorization.
Gene-based, single-dose AAVCOVID vaccine shown to offer disease protection in challenge study, and to elicit year-long immune response, according to new paper in Cell Host & Microbe.
A research team at the RIKEN Center for Emergent Matter Science (CEMS) in Japan has developed a diagnostic system that can rapidly and sensitively measure the amount of antibodies in the blood that can protect us from SARS-CoV-2, the virus that causes COVID-19.
In a new study by Yale Cancer Center, researchers show stem-like T cells within certain lymph nodes could be natural cancer fighters.
Wistar welcomes Amelia Escolano, Ph.D., and Nan Zhang, Ph.D., as assistant professors.
St. Jude Children’s Research Hospital scientists detail how inflammasomes act as integral components of mega-cell death complexes called PANoptosomes for host defense in live viral and bacterial infections.
Lab studies reveal protein HSP27’s role in blood vessel leakage, opening the possibility that therapeutically dialing its activity up or down might stabilize patients with sepsis.
A buildup of coronavirus in the lungs is likely behind the steep mortality rates seen in the pandemic, a new study finds. The results contrast with previous suspicions that simultaneous infections, such as bacterial pneumonia or overreaction of the body’s immune defense system, played major roles in heightened risk of death, the investigators say.
Nearly 90% of people taking immunosuppressants to treat autoimmune conditions produce an antibody response to COVID-19 vaccination, but the response is weaker than those generated by healthy people, according to a study by researchers at Washington University School of Medicine in St. Louis.
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