Patients who have multiple tumors in one breast may be able to avoid a mastectomy if the tumors can be removed while leaving enough breast tissue, according to research led by the Alliance in Clinical Trials in Oncology and Mayo Clinic Comprehensive Cancer Center.
Kristin Rojas, M.D., assistant professor of surgical oncology at Sylvester Comprehensive Cancer Center, has been awarded a three-year, $375,000 grant to investigate the role opioids may play in breast cancer.
Cosimo Commisso, Ph.D., and Susanne Heynen-Genel, Ph.D., have received a grant from the National Cancer Institute (NCI) to advance a new treatment approach for pancreatic cancer.
Immunotherapies have greatly improved the outcomes of many patients with melanoma. But there is still a need for new approaches for the subset of patients who do not respond well to this type of therapy. Moffitt Cancer Center researchers are looking at new targets to help inhibit tumor development and promote antitumor immunity, one being the STING signaling pathway. In a new article published in Nature Communications, a team of Moffitt and University of Miami Miller School of Medicine investigators demonstrate that targeting the STING pathway with a combination strategy results in improved antitumor activity.
The breast tumors of Asian, Black and white women have very different cellular, microbial and genomic features that could potentially be used to personalize care or predict disease progression, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center.
A new study finds some patients with early-stage lung cancer who receive a lobectomy do not fare better than patients who have less lung tissue removed.
Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited from the body's own immune system cells: a drastic loss of cancer-fighting fervor known as "exhaustion”.
Discrimination experienced by Black people can affect their health and increase their frailty, which can be particularly impactful for cancer survivors, according to a new study by researchers at Georgetown University’s Lombardi Comprehensive Cancer Center and colleagues at the Barbara Ann Karmanos Cancer Institute in Detroit. The researchers assessed frailty by a number of factors, including whether a participant had several chronic diseases, poor muscle strength and difficulty performing activities of daily living.
Chatbots and artificial intelligence are increasingly becoming more popular to answer questions about health. Researchers studied one of these resources, ChatGPT, to provide incredibly valuable and well-timed insights into the capabilities and limitations of artificial intelligence in the context of cancer-related information. Are people with cancer and their caregivers getting accurate answers?
In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).
In a new study published in the Journal of Clinical Oncology, Moffitt Cancer Center researchers report that a new smoking cessation intervention increased the number of patients who quit smoking compared to standard cessation approaches.
In a new study published in Nature Medicine, Moffitt Cancer Center physician-scientists, in collaboration with four cancer centers in the United States and Germany, reveal how microorganisms in the gut influence non-Hodgkin lymphoma patient outcomes to a type of cellular immunotherapy called chimeric antigen receptor T-cell therapy, or CAR T.
A combination treatment that targets the immune system helps treat aggressive prostate cancers that don’t respond to conventional therapies.
Mount Sinai Health System and Memorial Sloan Kettering Cancer Center researchers have developed a new drug delivery approach that uses nanoparticles to enable more effective and targeted delivery of anti-cancer drugs to treat brain tumors in children.
عادة ما يوجد تكاثر لنوع معين من الميكروبات في الجهاز التناسلي للنساء المصابات يسرطان المبيض، وفقًا لدراسة جديدة من مركز مايو كلينك لنهج الطب الشخصي. إن هذا الاكتشاف المنشور في مجلة التقارير العلمية يقوي الأدلة التي تشير إلى أن المكون البكتيري للحَيُّوم الدقيق - وهو مجتمع من الكائنات الحية الدقيقة يتكون أيضًا من فيروسات وخمائر وفطريات - من المؤشرات الهامة للكشف المبكر عن سرطان المبيض وتشخيصه والتنبؤ بسير المرض.
A team of researchers from institutions across the United States, including Moffitt Cancer Center, launched a phase 2 clinical trial evaluating a new treatment option for this patient population. Their results, published in The New England Journal of Medicine, show that treating resectable stage 3 and 4 melanoma patients with the immunotherapy drug pembrolizumab both before and after surgery greatly improves outcomes when compared to pembrolizumab given only after surgery.
Patients with high-risk melanoma who received the immunotherapy drug pembrolizumab both before and after surgery to remove cancerous tissue had a significantly lower risk of their cancer recurring than similar patients who received the drug only after surgery.
When older adults with cancer take multiple medications — including ordinary drugs like blood pressure pills, supplements, or antacids — it can result in more toxic chemotherapy side effects and even a need to stop cancer treatment.
Expert from Rutgers Cancer Institute of New Jersey & RWJBarnabas Health discusses what young people should know about colorectal cancer as the disease continues to rise in those ranging in age from mid-20's to 50's.
An interdisciplinary collaboration 10 years in the making used a materials science approach to “fingerprint” the calcium mineral deposits known as microcalcifications that reveal pathological clues to the progression of breast cancer and potentially other diseases.
This study shows vaccination against COVID-19 is an essential strategy to improve outcomes in this high-risk population. The results support guidelines that patients with cancer should receive at least 3 COVID-19 vaccine doses.
UC San Diego researchers report that a late-stage, pre-clinical small molecule inhibitor reverses malignant hyper-editing by a protein that promotes silencing of the immune response, metastasis and therapeutic resistance in 20 different cancer types.
When designing strategies to create lasting impact in a particular community, there is no better resource than the strength and intelligence of the community members themselves, and in this case, girls and women. Using crowdsourcing as a framework, a Saint Louis University researcher aims to increase HPV vaccination and HPV screening to lower incidents of cervical cancer among girls and women in Nigeria.
Researchers at The University of Texas MD Anderson Cancer Center have identified CD70 as being highly expressed on drug-resistant cancer cells in EGFR-mutant non-small cell lung cancer (NSCLC), highlighting a novel therapeutic target that could be used to eliminate resistant cells remaining after treatment with commonly used EGFR tyrosine kinase inhibitors (TKIs). The study published today in Cancer Cell.
In a new study published in the journal Cancer Immunology Research, our researchers, led by Amer A. Beg, Ph.D., show how stimulating dendritic cells through the CD40 and interferon β (IFNβ) pathways produces strong T cell activity against tumors and works in conjunction with immune checkpoint inhibitors to produce even stronger responses. The article also shares promising early results from a phase 1 clinical study of an oncolytic virus (MEM-288) that activates these pathways in patients with non-small cell lung cancer.
People who are unemployed due to brain or spine cancer may experience more severe symptoms of pain, discomfort, anxiety and depression than people with these cancers who are employed, according to a study published in the February 8, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Utilizing artificial intelligence (AI) along with traditional pathology offers promise for swiftly developing treatment plans for patients with non-small cell lung cancers, a team led by UT Southwestern Medical Center researchers discovered.
With a new five-year, $3.03 million grant from the National Cancer Institute—an agency of the National Institutes of Health—Case Western Reserve University researchers are leading the development and commercialization of a novel MRI and software technology that results in more accurate, consistent brain tumor diagnosis.
Mulheres com câncer em uma das mamas podem ter um risco mais elevado de desenvolver câncer na mama oposta caso sejam portadoras de mutações genéticas que as predisponham ao desenvolvimento de câncer de mama, de acordo com um estudo conduzido pelo Centro de Câncer da Mayo Clinic.
وفقًا لدراسة قادها مركز مايو كلينك الشامل للسرطان، فإن النساء المصابات بالسرطان في إحدى الثديين قد يكن أكثر عرضة للإصابة بالسرطان في الثدي الآخر إذا كنَّ حاملات لتغيرات جينية بعينها تجعلهن أكثر قابلية للإصابة بسرطان الثدي. يقول مؤلفو الدراسة إن النتائج المنشورة في مجلة مجلة علم الأورام السريرية، ستساعد في تخصيص أساليب فحص سرطان الثدي وتحديد عوامل الخطر وفقًا لحالة المريضة.
Risk model-based lung cancer screening strategies, which select individuals based on personal risk, are more cost effective than current recommendations based solely on age and smoking history, according to a study led by the Cancer Intervention and Surveillance Modeling Network (CISNET) Lung Working Group, which includes researchers from The University of Texas MD Anderson Cancer Center.
For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme. The findings could help address the growing threat of prostate cancer resistance and could also lead to improved treatments for other cancers.
UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery. The findings, reported in Cell, could lead to new ways of controlling gene regulation and may one day lead to new treatments for a broad array of diseases.
A new UC Davis study reveals the interaction between tumor microbiome and the immune system may be the secret to improving outcomes for sarcoma patients.
Inmazeb (REGN-EB3), developed by Regeneron, is a three-antibody cocktail designed to target the Ebola virus glycoprotein. The drug was first approved for clinical use in October 2020, but its exact mechanism of action has remained unclear.
In an academic-industrial collaboration, Mayo Clinic is assessing in a clinical trial a new radiotracer in pancreatic cancer imaging.
A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.
Researchers at Children’s Hospital of Philadelphia (CHOP) have developed a new computational tool that can more accurately discover and quantify RNA molecules from these error-prone long-read RNA sequencing data. The tool, called ESPRESSO (Error Statistics PRomoted Evaluator of Splice Site Options), was reported today in Science Advances.
Moffitt Cancer Center researchers have developed a tool to determine how a new class of prostate cancer therapies called radionuclide therapy (RNT) impacts patient-reported outcomes with the goal of using this information to guide treatment and improve quality of care. Their findings have been published in The Journal of Nuclear Medicine.
Columbia researchers invent a multimodal sequencing technique that achieves high-quality results from small volumes of frozen tumor specimens--the ability to study cancer tissues archived in biobanks should increase the number and variety of tumor samples available for scientific analysis and advance the discovery of biomarkers and drug targets.
National Comprehensive Cancer Network’s new Diversity, Equity, & Inclusion (DEI) Directors Forum is working together to improve diversity of clinical staff representation across nation’s leading academic cancer centers.
Physician experts from Rutgers Cancer Institute of New Jersey and RWJBarnabas Health will be presenting the latest innovations in the study, diagnosis and treatment of gastrointestinal cancers at the ASCO GI Cancers Symposium from January 19-21.
LA JOLLA, CA — Researchers at La Jolla Institute for Immunology (LJI) have at last uncovered how an enzyme called O-GlcNAc transferase (OGT) keeps cells healthy. Their findings, published in the Proceedings of the National Academies of Sciences, reveals a key aspect of cellular biology and may lead to important medical advances.
A new University of Kentucky Markey Cancer Center study highlights the need for increased outreach and education to reduce colorectal cancer screening disparities in Black communities. According to the qualitative study published in the Journal of Cancer Education, people in Kentucky’s Black communities may not be aware about all of the colorectal cancer screening options available to them, particularly stool-based tests.
Findings from a UC Davis Comprehensive Cancer Center study prompt researchers to question current cervical cancer screening guidelines for older women.
Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel immunotherapy combination, targeting checkpoints in both T cells and myeloid suppressor cells, that successfully reprogrammed the tumor immune microenvironment (TIME) and significantly improved anti-tumor responses in preclinical models of pancreatic cancer.
UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the risk variants themselves.
Showing results
1–50 of 500
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right
