Feature Channels: Personalized Medicine

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Newswise: Breaching the Blood-Brain Barrier to Deliver Precious Payloads
Released: 7-May-2021 11:35 AM EDT
Breaching the Blood-Brain Barrier to Deliver Precious Payloads
Georgia Institute of Technology

RNA-based drugs may change the standard of care for many diseases, making personalized medicine a reality. So far these cost-effective, easy-to-manufacture drugs haven’t been very useful in treating brain tumors and other brain disease. But a team of researchers at Georgia Tech and Emory University has shown that a combination of ultrasound and RNA-loaded nanoparticles can temporarily open the protective blood-brain barrier, allowing the delivery of potent medicine to brain tumors.

Newswise: Researchers speed identification of DNA regions that regulate gene expression
Released: 6-May-2021 12:10 PM EDT
Researchers speed identification of DNA regions that regulate gene expression
St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital scientists have developed a highly efficient method to address a major challenge in biology—identifying the genetic ‘switches’ that regulate gene expression.

Released: 5-May-2021 9:05 AM EDT
ATA Announces Women Advancing Thyroid Research Award Recipients
American Thyroid Association

The American Thyroid Association (ATA) celebrates the recipients of the Women Advancing Thyroid Research Award.  This award recognizes and honors the work of young women that are leading outstanding thyroid research.

Released: 4-May-2021 11:35 AM EDT
Immunomics: A Conversation on the Future of Diagnostics with Ramy Arnaout
Beth Israel Deaconess Medical Center

In a recent perspective article, pathologists outline how the immunome — all of the genes collectively expressed by an individual's immune cells — holds the potential to provide researchers and physicians with unprecedented insight into an individual's health. Collecting that information from large numbers of patients could one day facilitate diagnostics via a near-universal blood test and pave the way to targeted therapies for a wide variety of conditions.

Newswise: Breast Cancer Awareness: What Women Must Know
Released: 27-Apr-2021 2:40 PM EDT
Breast Cancer Awareness: What Women Must Know

To share important information related to breast cancer, we have compiled some of the latest research news related to breast cancer from top research institutions around the world.

Released: 27-Apr-2021 2:30 PM EDT
Discerning molecular interactions may be target of precision medicine for severe COVID-19
Bar-Ilan University

Scientific studies rarely focus on long non-coding RNA molecules (lncRNAs), even though they potentially regulate several diseases.

Newswise: Amazon Alexa skill offers supportive care to breast cancer patients
Released: 27-Apr-2021 10:30 AM EDT
Amazon Alexa skill offers supportive care to breast cancer patients
Penn State College of Medicine

Individuals with metastatic breast cancer could soon have access to personalized, supplemental supportive care through their smart speaker, thanks to new research at Penn State.

Newswise: Study Uses Precision Medicine to Speed Drug Testing for Pancreatic Cancer
Released: 15-Apr-2021 3:30 PM EDT
Study Uses Precision Medicine to Speed Drug Testing for Pancreatic Cancer
University of California San Diego Health

Moores Cancer Center at UC San Diego Health is among the few clinical trial sites in the U.S. for the Pancreatic Cancer Action Network’s (PanCAN) newly created Precision Promise, the first large-scale precision medicine trial designed to transform outcomes for patients with pancreatic cancer.

Released: 14-Apr-2021 10:05 AM EDT
Grant accelerates McMaster University, SQI Diagnostics effort to move infection testing innovation from lab to market
McMaster University

A new grant is helping McMaster University engineers and a Toronto precision-medicine diagnostics company to get infection-testing technology to market while generating opportunities for students.

Newswise: John Theurer Cancer Center Investigators Celebrate New Personalized Cell Therapy to Give Patients with Advanced Multiple Myeloma Hope
Released: 12-Apr-2021 9:00 AM EDT
John Theurer Cancer Center Investigators Celebrate New Personalized Cell Therapy to Give Patients with Advanced Multiple Myeloma Hope
Hackensack Meridian Health

The U.S. Food and Drug Administration recently approved a new CAR-T therapy called idecabtagene vicleucel (ide-cel), or Abecma. It’s the first personalized cell therapy to treat patients with multiple myeloma no longer responsive to all standard previous types of therapy. This new therapy was assessed in the pioneering phase II clinical KarMMA trial, at Hackensack Meridian John Theurer Cancer Center at Hackensack Meridian Hackensack University Medical Center.

Newswise: Blood Test for Depression Bipolar Disorder Offers Promise of Personalized Treatment
Released: 8-Apr-2021 8:30 AM EDT
Blood Test for Depression Bipolar Disorder Offers Promise of Personalized Treatment
Indiana University

Worldwide, 1 in 4 people will suffer from a depressive episode in their lifetime. While current diagnosis and treatment approaches are largely trial and error, a breakthrough study by Indiana University School of Medicine researchers sheds new light on the biological basis of mood disorders and offers a promising blood test aimed at a precision-medicine approach to treatment.

Released: 5-Apr-2021 4:00 PM EDT
Researchers Identify Genes Behind Uterine Leiomyosarcoma Which May Be Treated Using Precision Medicine
Yale Cancer Center

In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS).

5-Apr-2021 12:00 PM EDT
Personalized Cancer Vaccine Guided by Mount Sinai Computations Is Safe, Shows Potential Benefit Against Multiple Tumor Types
Mount Sinai Health System

A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and bladder, that have a high risk of recurrence, according to results from an investigator-initiated phase I clinical trial presented during the virtual American Association for Cancer Research (AACR) Annual Meeting 2021, held April 10-15.

Released: 1-Apr-2021 4:00 PM EDT
New system that uses smartphone or computer cameras to measure pulse, respiration rate could help future personalized telehealth appointments
University of Washington

A University of Washington-led team has developed a method that uses the camera on a person’s smartphone or computer to take their pulse and breathing rate from a real-time video of their face.

Released: 1-Apr-2021 12:45 PM EDT
UCI-led team awarded $2.3 million by California Initiative to Advance Precision Medicine
University of California, Irvine

A collaborative team centered in the University of California, Irvine (UCI) and including Children’s Hospital Orange County (CHOC) and Chapman University (CU) has been awarded a three-year grant totaling in excess of $2.3 million, to address the health impacts of adverse childhood experiences (ACEs) using precision medicine.

29-Mar-2021 1:25 PM EDT
Mount Sinai Study Reveals Genetic and Cellular Mechanisms of Crohn’s Disease
Mount Sinai Health System

New study identifies a novel approach for tailored treatment that could be more effective for patients with the chronic disease

Released: 30-Mar-2021 9:55 AM EDT
$2.5M award to fund joint organoid research program at Wake to treat aggressive cancers
Wake Forest Baptist Health

Personalized medicine research for aggressive abdominal cancers receives a boost with a new $2.5 million grant award from the National Cancer Institute that highlights research efforts by the Wake Forest Organoid Research Center (WFORCE).

Released: 25-Mar-2021 8:50 AM EDT
الطب الدقيق، والتكنولوجيا الرقمية لديهما إمكانات كأدوات قوية ضد داء السل
Mayo Clinic

تكتسب المعركة العالمية ضد داء السل بعض الأدوات القوية. الطب الدقيق — المُستخدم بالفعل لتخصيص تشخيص الأمراض غير المعدية وعلاجها، مثل: السرطان — وتقنيات الرعاية الصحية، مثل: الطب عن بُعد، لديهما القدرة على تطوير الوقاية والعلاج من داء السل، كما يقول زلالم تمسجين، دكتور الطب، خبير الأمراض المعدية والمدير الطبي لمركز داء السل التابع لمايو كلينك.

Released: 23-Mar-2021 5:00 PM EDT
A medicina de precisão e a tecnologia digital apresentam potencial como ferramentas poderosas contra a tuberculose
Mayo Clinic

A luta global contra a tuberculose está ganhando algumas ferramentas poderosas. A medicina de precisão — já usada para personalizar o diagnóstico e o tratamento de doenças não transmissíveis, como o câncer — e as tecnologias de saúde, como a telemedicina, têm potencial para avançar na prevenção e no tratamento da tuberculose, afirma Zelalem Temesgen, M.D.

Released: 23-Mar-2021 4:55 PM EDT
Mayo Clinic

全球抗击肺结核的努力获得了医疗技术的强大助力。精准医学已经用于非传染性疾病(例如癌症)的诊断和治疗,它和远程医学等医疗技术有可能促进结核病的预防和治疗,妙佑医疗国际 (Mayo Clinic) 肺结核中心的传染病专家和医学主任 Zelalem Temesgen 医学博士 说。

Released: 22-Mar-2021 5:05 PM EDT
Medicina de precisión y tecnología digital como instrumentos poderosos contra la tuberculosis
Mayo Clinic

La lucha mundial contra la tuberculosis ahora cuenta con algunos instrumentos poderosos. La medicina de precisión que ya se aplica para personalizar el diagnóstico y el tratamiento de enfermedades no contagiosas, como el cáncer, junto a las tecnologías para la atención de la salud, como la telemedicina, tienen la capacidad de avanzar la prevención y el tratamiento de la tuberculosis, dice el Dr. Zelalem Temesgen, experto en enfermedades infecciosas y director médico del Centro para Tuberculosis en Mayo Clinic.

Released: 22-Mar-2021 4:50 PM EDT
Precision medicine, digital technology hold potential as powerful tools against tuberculosis
Mayo Clinic

The global fight against tuberculosis is gaining some powerful tools. Precision medicine — already used to personalize diagnosis and treatment of noncommunicable diseases such as cancer — and health care technologies such as telemedicine have the potential to advance the prevention and treatment of tuberculosis, says Zelalem Temesgen, M.D., an infectious diseases expert and medical director of the Mayo Clinic Center for Tuberculosis.

17-Mar-2021 9:00 AM EDT
Combination thyroid hormone therapies treat hypothyroidism as well as levothyroxine
Endocrine Society

Treatment of hypothyroidism, which results from an underactive thyroid gland, should be individualized and consideration should be given to alternatives to the first-line therapy, including desiccated thyroid extract and combination therapy to replace the body’s two main thyroid hormones, thyroxine (T4) and triiodothyronine (T3). Results of their new randomized clinical study are being presented at ENDO 2021, the Endocrine Society’s annual meeting.

18-Mar-2021 3:00 PM EDT
Lack of diversity in genomic databases may affect therapy selection for minority groups
Mayo Clinic

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology. The researchers investigated the use of genomic databases and found that tumor mutation burden was significantly inflated in Black patients compared to White patients. As a result of the study, clinicians who are using public genomic databases need to be aware of the potential for inflated tumor mutation burden values and how that may affect therapy selection and outcomes, especially for patients from underrepresented groups.

Released: 9-Mar-2021 2:05 PM EST
Corrona Announces Name Change to CorEvitas and Expanded Strategic Direction
Corrona, LLC

Corrona, LLC, a leading provider of real-world evidence solutions, announced today that it has changed its name to CorEvitas [kohr-eh'-vi-tahs].

Newswise: Healthcare Executive Martha R. Temple Joins Coriell Life Sciences Board of Directors
Released: 9-Mar-2021 9:00 AM EST
Healthcare Executive Martha R. Temple Joins Coriell Life Sciences Board of Directors
Coriell Life Sciences

Genetic science is a game-changer for medication safety and healthcare overall, and Coriell Life Sciences is leading the way in unlocking its full potential through precision medicine.

Newswise: New classification of leukemia subtypes reveals potential of personalized treatment using existing drugs
16-Feb-2021 5:00 AM EST
New classification of leukemia subtypes reveals potential of personalized treatment using existing drugs
University Health Network (UHN)

Using advanced RNA sequencing, scientists have identified two unique subtypes of a prominent mutation present in many patients with Acute Myeloid Leukemia (AML) – called NPM1 – that could help predict survival and improve treatment response for patients whose leukemic cells bear the mutation.

Released: 1-Feb-2021 3:05 AM EST
Curcumin Selected as Cognition Supplement of the Year: 2021, says Dr. Leslie Norins of MCI911.com
MCI 911

As yet there is no prescription drug to cure mild cognitive impairment (MCI), often a harbinger of Alzheimer's disease. Medical research journals reveal curcumin can sometimes bolster cognition. It merits a try.

Released: 26-Jan-2021 12:20 PM EST
Biotechnology research and policy expert joins Thunderbird School of Global Management and Sandra Day O’Connor College of Law at ASU through World Economic Forum fellowship
Thunderbird School of Global Management

Thunderbird School of Global Management announces the first of two prestigious Hoffmann Fellowships appointed in collaboration with the World Economic Forum for post-doctoral research and policy innovation at the intersection of society, science and technology.

22-Jan-2021 4:05 PM EST
Nanomedicine’s ‘crown’ is ready for its close up
Michigan State University

An international team of researchers led by Michigan State University’s Morteza Mahmoudi has developed a new method to better understand how nanomedicines — emerging diagnostics and therapies that are very small yet very intricate — interact with patients’ biomolecules.

Released: 21-Jan-2021 12:05 PM EST
Dynamic, personalized treatment approach may improve outcomes in gastroesophageal cancers
University of Chicago Medical Center

A phase 2 clinical trial providing personalized treatments based on the genetic profile of metastatic tumors in gastroesophageal cancers has found that using customized treatment approaches, and adapting them over time as tumors become resistant, led to higher rates of survival compared to historical controls.

Newswise: Personalizing Cancer Care with Improved Tumor Models
Released: 21-Jan-2021 11:45 AM EST
Personalizing Cancer Care with Improved Tumor Models
American Institute of Physics (AIP)

While decades of research have resulted in substantial improvements in surviving cancer, a key challenge remains in identifying new drugs that improve outcomes for patients. In APL Bioengineering, researchers suggest a major hurdle is the paucity of models for cancer research that accurately represent patient tumors. They provide a perspective on strategies using models from individual patients and where the field needs to go in terms of research in animal systems and in culture systems.

Released: 21-Jan-2021 11:40 AM EST
Study defines small-cell lung cancer subtypes and distinct therapeutic vulnerabilities for each type
University of Texas M. D. Anderson Cancer Center

Researchers from The University of Texas MD Anderson Cancer Center have developed the first comprehensive framework to classify small-cell lung cancer (SCLC) into four unique subtypes, based on gene expression, and have identified potential therapeutic targets for each type in a study published today in Cancer Cell.

Newswise: First Patient Enrolls In PRECISIONS Study For Treatment Of Idiopathic Pulmonary Fibrosis
Released: 11-Jan-2021 12:05 PM EST
First Patient Enrolls In PRECISIONS Study For Treatment Of Idiopathic Pulmonary Fibrosis
Pulmonary Fibrosis Foundation

Today, the Pulmonary Fibrosis Foundation (PFF) announced enrollment of the first patient in PRECISIONS (Prospective tReatment EffiCacy in IPF uSIng genOtype for Nac Selection) clinical trial. This is the first clinical trial to apply the principles of precision medicine to the treatment of patients with idiopathic pulmonary fibrosis (IPF).

Newswise: huss-wei-foster-paragh-color_dec2020-1.jpg
Released: 4-Jan-2021 8:10 AM EST
Roswell Park Experts Use Gene Sequencing to Quantify Risk of Skin Cancer Long Before Damage is Visible
Roswell Park Comprehensive Cancer Center

In a study published today in the journal Science Advances, a team from Roswell Park details a method to measure the abundance of cancer-related early changes to skin tissue long before the damage becomes visible to the eye.

Released: 18-Dec-2020 9:30 AM EST
Case Western Reserve University teams with Boehringer Ingelheim on artificial intelligence solutions for precision medicine
Case Western Reserve University

The Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University and Boehringer Ingelheim, one of the world’s largest pharmaceutical companies will leverage the power of CCIPD’s image computing AI solutions to identify patterns and links between cellular response and underlying molecular drivers, with the goal of advancing therapeutics for diseases with no satisfactory treatment option.

Newswise:Video Embedded alcediag-to-announce-game-changing-solutions-in-mental-health-diseases-diagnostic-tools-based-on-rna-editing-blood-biomarkers
Released: 16-Dec-2020 11:50 AM EST
ALCEDIAG to announce game changing solutions in mental health diseases & diagnostic tools based on RNA-editing blood biomarkers
2020 AACC Annual Scientific Meeting Press Program

ALCEDIAG, one of 3 finalists for the “Disruptive Technology Award” at the annual AACC meeting 2020, will be holding a press conference to announce a game-changing technology and diagnostic tool for precision medicine in psychiatry: EDIT-BTM, the very first blood test for a high-performance differential diagnosis of unipolar depression and bipolar disorder.

Newswise:Video Embedded advances-in-covid-19-testing-artificial-intelligence-cancer-therapies-and-the-future-of-precision-medicine-to-be-explored-at-the-all-virtual-2020-aacc-annual-scientific-meeting
10-Dec-2020 10:10 AM EST
Advances in COVID-19 Testing, Artificial Intelligence, Cancer Therapies, and The Future of Precision Medicine to Be Explored at The All-Virtual 2020 AACC Annual Scientific Meeting
American Association for Clinical Chemistry (AACC)

In the wake of the novel coronavirus pandemic, the need for reliable, accurate, and accessible laboratory testing is more evident than ever before. At the 2020 AACC Annual Scientific Meeting & Clinical Lab Expo, laboratory medicine experts will present the cutting-edge research and technology that is revolutionizing clinical testing and patient care for COVID-19 and across the spectrum of healthcare.

Newswise:Video Embedded despite-covid-19-pandemic-first-patient-undergoes-new-personalized-immunotherapy
Released: 10-Dec-2020 11:15 AM EST
Despite COVID-19 Pandemic First Patient Undergoes New Personalized Immunotherapy
University of California San Diego Health

Bernard Thurman was referred to a personalized cancer therapy trial at Moores Cancer Center at UC San Diego Health, a collaboration with the La Jolla Institute for Immunology, the trial employs a patient’s immune cells — specifically tumor infiltrating lymphocytes (TIL) — to destroy cancer cells.

Newswise: Henry Ford Health System Receives $16 Million Gift to Benefit Henry Ford Pancreatic Cancer Center
Released: 7-Dec-2020 12:20 PM EST
Henry Ford Health System Receives $16 Million Gift to Benefit Henry Ford Pancreatic Cancer Center
Henry Ford Health System

Henry Ford Health System today announced a $16 million gift to its Henry Ford Pancreatic Cancer Center (HFPCC), which was launched in 2018 by an initial $20 million gift from the same donor, who wishes to remain anonymous. The gift will bolster the HFPCC’s clinical and translational research endeavors in the fight against this devastating disease, for which the five-year survival rate is only 9 percent.

Released: 7-Dec-2020 8:20 AM EST
New Biomarker Identifies Patients with Aggressive Lymphoma Who Don’t Respond to Precision Therapy
Perelman School of Medicine at the University of Pennsylvania

A new biomarker discovered by a team that includes researchers from Penn Medicine identifies patients with an aggressive form of lymphoma unlikely to respond to the targeted treatment ibrutinib.

Released: 1-Dec-2020 8:45 AM EST
Environmental exposures affect therapeutic drugs
University of Vienna

High-resolution mass spectrometry promotes new methods for analysis. Humans are exposed to various environmental or dietary molecules that can attenuate or even increase the effect of therapeutic drugs. Studies on the industrial chemical bisphenol A and the phytoestrogen genistein, for example, have shown drug-exposome interactions.

Newswise: Coriell Life Sciences Wins Two Prestigious Industry Awards
Released: 23-Nov-2020 9:00 AM EST
Coriell Life Sciences Wins Two Prestigious Industry Awards
Coriell Life Sciences

Coriell Life Sciences, a trusted and innovative precision medicine organization, is honored to accept two industry awards: EHIR's Fall 2020 Traction Award Healthcare Tech Outlook's Top Precision Medicine Providers in Europe

Released: 19-Nov-2020 2:15 PM EST
Fred Hutch at ASH: Fauci fireside chat, latest on cell therapies, repairing immune function, COVID and clots — and more
Fred Hutchinson Cancer Research Center

SEATTLE — Nov. 18, 2020 — Fred Hutchinson Cancer Research Center’s latest findings on cell therapies, repairing immune function, and more will be featured at the 62nd American Society of Hematology Annual Meeting & Exposition, to be held virtually Dec. 5 – 8.Dr. Stephanie Lee, ASH president and Fred Hutch physician-scientist will kick off the meeting with a fireside chat with Dr.

Newswise: New Map of the Immune Landscape in Pancreatic Cancer Could Guide Future Personalized Immunotherapy Treatments
Released: 26-Oct-2020 1:05 PM EDT
New Map of the Immune Landscape in Pancreatic Cancer Could Guide Future Personalized Immunotherapy Treatments
Michigan Medicine - University of Michigan

A new analysis highlights the diversity of immune response in pancreatic cancer, and points toward the need for treatments tailored to individual patients.

Newswise: DrugCell: New Experimental AI Platform Matches Tumor to Best Drug Combo
Released: 22-Oct-2020 4:20 PM EDT
DrugCell: New Experimental AI Platform Matches Tumor to Best Drug Combo
University of California San Diego Health

UC San Diego researchers use experimental artificial intelligence system called DrugCell to predict the best approach to treating cancer.

Newswise: Study reports chemical mechanism that boosts enzyme observed in cancer
Released: 20-Oct-2020 9:05 PM EDT
Study reports chemical mechanism that boosts enzyme observed in cancer
Indiana University

A study led by researchers at IUPUI and Indiana University Bloomington is the first to describe a biochemical mechanism that influences activity in a protein linked to cancer, aging, inflammatory responses and addiction-related behaviors.

Released: 19-Oct-2020 11:20 AM EDT
Mount Sinai Doctors Elected to National Academy of Medicine for Contributions to Emergency Medicine and Translational Genetics
Mount Sinai Health System

Brendan G. Carr, MD, MA, MS, and Judy H. Cho, MD, of the Icahn School of Medicine at Mount Sinai, have been elected to the National Academy of Medicine (NAM).

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