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This news release is embargoed until 10-Dec-2022 5:10 PM EST Released to reporters: 6-Dec-2022 10:05 AM EST

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Released: 2-Dec-2022 6:30 PM EST
No ‘one size fits all’ solution to treating early-onset psychosis
University of Birmingham

Gold standard treatment plans for people with early psychosis have a patchy success rate, suggesting the need to develop more tailored approaches.

Newswise: Do women age differently from men?
Released: 1-Dec-2022 7:30 PM EST
Do women age differently from men?
Max Planck Institute for Biology of Ageing

The life expectancy of women is significantly higher than that of men.

29-Nov-2022 10:45 AM EST
New Genetic Mutation Behind Childhood Glaucoma Identified
Massachusetts Eye and Ear

An international team of researchers led by Mass Eye and Ear discovered a new genetic mutation that leads to childhood glaucoma, and in the process uncovered a new mechanism for causing the disease.

Newswise: St. Joseph’s Health and Hackensack Meridian Health: 20th Anniversary of Acute Rehabilitation Unit & One-Year Anniversary of Rehabilitation Partnership
Released: 23-Nov-2022 10:20 AM EST
St. Joseph’s Health and Hackensack Meridian Health: 20th Anniversary of Acute Rehabilitation Unit & One-Year Anniversary of Rehabilitation Partnership
Hackensack Meridian Health

“We are delighted to celebrate the one year anniversary of our rehabilitation clinical affiliation with St. Joseph’s Health,” said Robert C. Garrett, FACHE, CEO, Hackensack Meridian Health. “Throughout the state, our rehab experts have been improving lives through their vast expertise in healing and restoring quality of life after a serious illness or traumatic episode. This affiliation has placed our advanced services closer to home for residents of Northern New Jersey.”

Released: 22-Nov-2022 7:20 PM EST
New study brings personalized immunotherapy prescriptions a step closer
University of Bath

In a step likely to advance personalised cancer treatment, scientists have for the first time shown in patients that levels of biomarkers are not enough to tell which patients are likely to respond best to immunotherapy.

Newswise: Wearable Activity Trackers Can Be Used to Determine Health Metrics That Could Support Clinical Care
Released: 17-Nov-2022 12:00 PM EST
Wearable Activity Trackers Can Be Used to Determine Health Metrics That Could Support Clinical Care
Johns Hopkins Medicine

A new Johns Hopkins study shows that data gathered from wearable activity trackers can be used to obtain several metrics associated with the user’s general physical health and cardiovascular health status.

Newswise: KU Medical Center researchers receive R01 grant from National Cancer Institute to increase targeted cancer treatments to rural cancer patients
Released: 16-Nov-2022 2:40 PM EST
KU Medical Center researchers receive R01 grant from National Cancer Institute to increase targeted cancer treatments to rural cancer patients
University of Kansas Cancer Center

TEAMSPORT will create a standardized approach to ordering genomic tests and adapt it for use in community cancer centers, where most cancer patients receive testing and treatment.

Released: 10-Nov-2022 11:25 AM EST
Immune system reboot in MS patients
University of Zurich

Every day, one person in Switzerland is diagnosed with multiple sclerosis. MS is an autoimmune disease in which the body’s own immune system attacks the myelin sheath of the nerve cells in the brain and spinal cord.

9-Nov-2022 9:00 AM EST
First use of CRISPR to substitute genes to treat patients with cancer
University of California, Los Angeles (UCLA), Health Sciences

For the first time, scientists have used CRISPR technology to insert genes that allow immune cells to focus their attack on cancer cells, potentially leaving normal cells unharmed and increasing the effectiveness of immunotherapy.

Newswise: CRISPR Treatment Slows Swelling in Hereditary Angioedema Patients
4-Nov-2022 8:00 AM EDT
CRISPR Treatment Slows Swelling in Hereditary Angioedema Patients
American College of Allergy, Asthma and Immunology (ACAAI)

A new study being presented at this year’s ACAAI Annual Scientific Meeting shows a treatment using the CRISPR genome editing technology succeeded in alleviating swelling and reducing the frequency of attacks.

Released: 9-Nov-2022 3:15 PM EST
Knowledge is power. The latest research on arthritis is right at your fingertips
Newswise

Here are some of the latest articles that have been added to the Arthritis channel on Newswise.

Released: 7-Nov-2022 8:05 AM EST
Adding Sensory Integration to Autism Assessments may yield More Individualized Treatment
Thomas Jefferson University

Additional insights can help guide interventions that can assist individuals in processing and understanding their surroundings better.

4-Nov-2022 11:20 AM EDT
Personalising whole genome sequencing doubles diagnosis of rare diseases
University College London

Tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases, finds a new study led by UCL researchers.

2-Nov-2022 9:45 AM EDT
High-Impact Clinical Trials Yield Results that Could Improve Kidney Care
American Society of Nephrology (ASN)

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented in-person and online at ASN Kidney Week 2022 November 3–November 6.

Released: 28-Oct-2022 10:05 AM EDT
Cleveland Clinic Receives $12 Million NIH Grant to Investigate Use of Inflammatory Cytokines in Personalized Cancer Treatments
Cleveland Clinic

Cleveland Clinic’s Lerner Research Institute was awarded a five-year $12 million grant by the National Cancer Institute, part of the National Institutes of Health, to define how cytokines - proteins produced during immune response - regulate inflammation and interact with cells and molecules surrounding tumors.

Newswise: Ochsner Health Oncologist Wins National Award for Precision Cancer Therapies
Released: 24-Oct-2022 10:05 AM EDT
Ochsner Health Oncologist Wins National Award for Precision Cancer Therapies
Ochsner Health

Dr. Marc Matrana recognized for innovative work in cancer research and precision cancer therapies.

Released: 18-Oct-2022 4:05 PM EDT
Vasa Therapeutics Announces Upcoming Presentations at AHA Scientific Sessions 2022
Vasa Therapeutics, Inc.

Vasa Therapeutics, Inc., a preclinical stage company developing first-in-class treatments for cardiovascular indications with limited or no available therapies, today announced two upcoming poster presentations showing data on the company's lead clinical candidate, VS-041, a selective matrix metalloprotease (MMP) inhibitor for treatment of heart failure with preserved ejection fraction (HFpEF) and the discovery of novel calcium/calmodulin-dependent protein kinase II delta (CaMKIIδ) inhibitors for treatment of β-blocker resistant arrythmias, at the American Heart Association (AHA) Scientific Sessions November 5 – 7 in Chicago, IL.

   
Newswise: Gases Intestinales Vinculados a Tipos Específicos de Síndrome del Intestino Irritable
Released: 18-Oct-2022 3:05 PM EDT
Gases Intestinales Vinculados a Tipos Específicos de Síndrome del Intestino Irritable
Cedars-Sinai

Un nuevo estudio dirigido por investigadores de Cedars-Sinai encontró que el uso de pruebas de aliento para identificar perfiles de gases intestinales puede conducir a terapias más personalizadas para personas diagnosticadas con síndrome del intestino irritable (SII). El trastorno gastrointestinal más común afecta del 10% al 15% de la población mundial.

Newswise: Study: Regional Differences Identified in Polycystic Ovary Syndrome Patients
Released: 12-Oct-2022 12:10 PM EDT
Study: Regional Differences Identified in Polycystic Ovary Syndrome Patients
Cedars-Sinai

The environment could be playing a critical role in the expression of polycystic ovary syndrome (PCOS) in women living in Alabama, as compared to women in California, according to a new study published in the Journal of Clinical Endocrinology & Metabolism.

Released: 12-Oct-2022 10:00 AM EDT
Computer platform helps match patients with cancer to trials of targeted therapy
Dana-Farber Cancer Institute

As more patients with cancer have their tumors genomically profiled, and more therapies targeting genomic alterations enter clinical trials, the task of connecting patients to trials for which they are eligible can be especially challenging. A computer platform developed at Dana-Farber Cancer Institute makes the matching process both easier and faster, its designers report in a new study.

Released: 7-Oct-2022 12:05 PM EDT
Research provides critical information about the size and growth speed of gliomas
Mayo Clinic

An important new clue for preventing and treating brain tumors known as gliomas has been identified in research led by the Lunenfeld-Tannenbaum Research Institute (LTRI) at Mount Sinai Hospital in Toronto and Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine. The study, published in the journal Science, provides a rare window into the biological changes behind glioma development.

29-Sep-2022 5:00 PM EDT
Endocrine Society experts recommend individualized approach to use of telehealth
Endocrine Society

Following rapid growth during the COVID-19 pandemic, telehealth visits are expected to remain an important part of endocrine care, according to a new Endocrine Society policy perspective published in The Journal of Clinical Endocrinology & Metabolism.

Released: 3-Oct-2022 10:05 AM EDT
Mayo study lays foundation to predict antidepressant response in people with suicide attempts
Mayo Clinic

Mayo Clinic researchers have discovered that people with major depressive disorder and a history of attempted suicide have distinct biomarkers that correlate with their response to antidepressant therapy. The new findings, published in Frontiers Pharmacology, are key to individualized treatment strategies and early identification of patients who are at the highest risk for suicide.

Newswise: AAP 2022 to Feature Cedars-Sinai Guerin Children’s Clinicians and Researchers
Released: 30-Sep-2022 12:45 PM EDT
AAP 2022 to Feature Cedars-Sinai Guerin Children’s Clinicians and Researchers
Cedars-Sinai

Cedars-Sinai Guerin Children’s pediatric specialists will share their expertise and recent research findings at the American Academy of Pediatrics Annual Meeting, taking place Oct. 7-11 in Anaheim, California.

Released: 28-Sep-2022 9:35 AM EDT
Machine learning creates opportunity for new personalized therapies
Michigan Medicine - University of Michigan

Researchers at the University of Michigan Rogel Cancer Center have developed a computational platform that can predict new and specific metabolic targets in ovarian cancer, suggesting opportunities to develop personalized therapies for patients that are informed by the genetic makeup of their tumors. The study appeared in Nature Metabolism.

Newswise: Cleveland Clinic Receives $7.9 Million Grant from National Institutes of Health to Form Radiation Oncology-Biology Integration Network (ROBIN)
Released: 22-Sep-2022 4:10 PM EDT
Cleveland Clinic Receives $7.9 Million Grant from National Institutes of Health to Form Radiation Oncology-Biology Integration Network (ROBIN)
Cleveland Clinic

Cleveland Clinic received a $7.9 million five-year grant from the National Cancer Institute at the National Institutes of Health to form one of three national centers as part of the newly established Radiation Oncology-Biology Integration Network (ROBIN).

Newswise: NIH Funds Miller School Researcher's Novel Work to Develop Gene Therapy for Hearing Loss-related Usher Syndrome
Released: 22-Sep-2022 2:30 PM EDT
NIH Funds Miller School Researcher's Novel Work to Develop Gene Therapy for Hearing Loss-related Usher Syndrome
University of Miami Health System, Miller School of Medicine

The National Institute on Deafness and Other Communication Disorders (NIDCD) has awarded Xue Zhong Liu, M.D., Ph.D., Marian and Walter Hotchkiss Endowed Chair in Otolaryngology at the University of Miami Miller School of Medicine, a five-year, $3.5 million R01 research grant to develop a precision medicine approach to treat hearing loss (HL) in Usher syndrome (USH).

Released: 21-Sep-2022 11:05 AM EDT
Integrating Genetic Testing in Electronic Health Records Saves Time, Study Finds
Perelman School of Medicine at the University of Pennsylvania

Ordering and managing genomic testing in electronic health records significantly cut the time Penn Medicine clinicians spent doing it

Newswise: 210114_Chow_monoclonal_0335_sz-768x488.jpg
Released: 19-Sep-2022 5:05 PM EDT
Precision Health Perspectives
University of California, Irvine

In February, UCI launched the Institute for Precision Health, a campus-wide, interdisciplinary endeavor that merges UCI’s powerhouse health sciences, engineering, machine learning, artificial intelligence, clinical genomics and data science capabilities. The objective is to identify, create and deliver the most effective health and wellness strategy for each individual person and, in doing so, confront the linked challenges of health equity and the high cost of care.

Released: 16-Sep-2022 9:45 AM EDT
Mount Sinai Health System Hospitals Place Among World’s Best in Newsweek/Statista Rankings
Mount Sinai Health System

The Mount Sinai Hospital, Mount Sinai Beth Israel, and Mount Sinai Morningside place among the world's best in Newsweek/Statista rankings.

Released: 15-Sep-2022 4:05 PM EDT
Gay men are two times more likely to have inflammatory bowel disease, according to new research
Case Western Reserve University

Gay men are more than twice as likely to develop inflammatory bowel disease (IBD) than heterosexual men when both populations engage in high-risk sexual activity, according to new research from the Digestive Health Research Institute at Case Western Reserve University and University Hospitals Cleveland Medical Center (UH).

12-Sep-2022 11:05 AM EDT
Muscle Models Mimic Diabetes, Inform Personalized Medicine
American Institute of Physics (AIP)

Scientists are using in vitro skeletal muscle engineering to gain a better understanding of the complex genetic and environmental factors underlying diabetes, putting lab-grown, healthy skeletal muscle tissues in a state resembling diabetes or growing skeletal muscle from diabetic patients' muscle stem cells. In Biophysics Reviews, researchers describe how skeletal muscle engineering has advanced significantly during the past few decades and recent developments that make it easier to explore diabetes in humans and have led to more personalized medicine.

   
Released: 13-Sep-2022 9:50 AM EDT
FSU psychologist awarded $9M to expand gamified treatments for pediatric ADHD
Florida State University

Millions of children are diagnosed each year with attention-deficit/hyperactivity disorder, or ADHD. When untreated, or undertreated, children with ADHD face challenges focusing, managing time, and practicing self-control, and these difficulties can persist into adulthood.

Newswise: RET inhibitor selpercatinib demonstrates durable responses in tumor-agnostic population
12-Sep-2022 2:35 PM EDT
RET inhibitor selpercatinib demonstrates durable responses in tumor-agnostic population
University of Texas M. D. Anderson Cancer Center

The highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses across multiple tumor types in the Phase I/II LIBRETTO-001 trial.

Released: 9-Sep-2022 1:15 PM EDT
UCLA Health researchers analyze LA’s ‘stunningly diverse’ genetic ancestry to bring ethnic equity to precision medicine
University of California, Los Angeles (UCLA), Health Sciences

Analyzing genetic ancestry data from a large genomic repository – the UCLA ATLAS Precision Health Biobank – researchers have found a highly diverse patient population that’s consistent with the global diversity of Los Angeles – one of the most ethnically diverse cities in the world and an ideal location to pursue personalized, precision medicine for underrepresented populations.

Released: 8-Sep-2022 11:10 AM EDT
How can you explain the pain? Get the latest research on pain management in the Pain channel
Newswise

The latest research and expert commentary on pain management.

Released: 8-Sep-2022 10:05 AM EDT
Fred Hutchinson Cancer Center receives $78 million gift to support precision oncology
Fred Hutchinson Cancer Center

Stuart and Molly Sloan have pledged $78 million to support Fred Hutchinson Cancer Center. It is the largest single gift in Fred Hutch’s 47-year history.“Miracles begin in the lab, and nowhere else is that truer than at Fred Hutch,” said Stuart Sloan. “I’ve been involved with this organization for years, and during that time, I have had the opportunity to personally interact with the scientists and leaders who are making this progress possible.

Released: 8-Sep-2022 9:45 AM EDT
Investigadores de Mayo Clinic precisan variaciones genéticas que podrían cambiar el curso de la COVID-19
Mayo Clinic

Los investigadores del Centro para Medicina Personalizada en Mayo Clinic descubrieron en el genoma humano firmas decisivas que podrían explicar por qué la COVID-19 es tan grave en algunas personas y leve en otras.

Released: 6-Sep-2022 3:30 PM EDT
CHOP Researchers Implicate Multiple Causal Genes that Drive Type 2 Diabetes Risk
Children's Hospital of Philadelphia

Researchers from Children’s Hospital of Philadelphia (CHOP) used advanced three-dimensional mapping techniques at a microscopic level to identify a multitude of genetic variants and corresponding target gene pairings in the pancreas that are implicated in type 2 diabetes. In addition to these discoveries, the resulting datasets will serve as a key resource for researchers all over the world to delve deeper into the genetic origins of type 2 diabetes and further explore the roles of different types of cells in the development of the disease.

Newswise: Magnus Medical Receives FDA Clearance for the SAINT Neuromodulation System for Non-Invasive, Individualized and Precise Treatment of Severe Depression
Released: 6-Sep-2022 10:05 AM EDT
Magnus Medical Receives FDA Clearance for the SAINT Neuromodulation System for Non-Invasive, Individualized and Precise Treatment of Severe Depression
Magnus Medical

Magnus Medical received clearance from the U.S. FDA for the SAINT™ Neuromodulation System for the treatment of major depressive disorder in adults who have failed to achieve satisfactory improvement from prior antidepressant medications.

Released: 29-Aug-2022 3:10 PM EDT
Advancing Precision Oncology, Ochsner Health First to Fully Integrate with Tempus and Epic's Genomics Module
Ochsner Health

Ochsner Health, through its Precision Medicine Program, is the first in the nation to incorporate Epic’s Orders and Results Anywhere integration with its Genomics module.

Released: 25-Aug-2022 12:40 PM EDT
妙佑医疗国际(Mayo Clinic)的研究人员精准确定可能影响COVID-19病程的基因变异
Mayo Clinic

妙佑医疗国际个体化医学中心的研究人员已经发现了助于解释为何COVID-19在一些患者中引起重症而在另一些患者中引起轻症的关键人类基因组特征。在分析了全球大量不同的DNA序列数据后,科学家们在两种人类蛋白质中发现了可能影响SARS-CoV-2(即导致COVID-19的病毒)感染病程的突变。

Released: 25-Aug-2022 12:35 PM EDT
باحثو مايو كلينك يحددون الاختلافات الجينية التي قد تؤثر في مسار كوفيد-19
Mayo Clinic

اكتشف الباحثون في مركز مايو كلينك لنهج الطب الشخصي التوقيعات الجينومية البشرية الرئيسية التي قد تساعد في تفسير سبب كون فيروس كورونا المستجد (كوفيد-19) شديدًا لدى بعض الأشخاص ومعتدلًا لدى آخرين.

Released: 25-Aug-2022 12:25 PM EDT
Pesquisadores da Mayo Clinic identificam variações genéticas que podem influenciar o curso da COVID-19
Mayo Clinic

Pesquisadores do Centro de Medicina Individualizada da Mayo Clinic descobriram assinaturas genômicas importantes que podem explicar por que a COVID-19 é grave para algumas pessoas e leve para outras.

Released: 22-Aug-2022 3:45 PM EDT
Find expert commentary on the monkeypox outbreak here
Newswise

The latest research and expert commentary on the monkeypox outbreak.

Newswise: Groundbreaking Research Hopes to Personalise Treatment for Cancer Patients
Released: 22-Aug-2022 12:05 AM EDT
Groundbreaking Research Hopes to Personalise Treatment for Cancer Patients
University of South Australia

Cancer Council SA-funded researcher Associate Professor Stephanie Reuter Lange from UniSA hopes that a simple computer program can help personalise treatment for cancer patients.


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