Feature Channels: Vaccines

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20-Nov-2020 8:50 AM EST
Over half of adults over 50 say they’ll get vaccinated against COVID-19, but many will want to wait, poll finds
Michigan Medicine - University of Michigan

A new poll of adults ages 50 to 80 suggests that achieving the widespread vaccination against COVID-19 needed to protect this high-risk group and end the pandemic will be an uphill climb, and require clear, transparent communication from health providers and others.

Released: 20-Nov-2020 2:25 PM EST
Testing Wastewater for COVID-19
University of Nevada, Las Vegas (UNLV)

UNLV researcher Edwin Oh and colleagues have implemented wastewater surveillance programs to screen samples for the presence of COVID-19 and to extract the RNA from the SARS-COV-2 virus to find targets that make vaccines more effective.

   
Released: 20-Nov-2020 1:40 PM EST
MMR vaccine could protect against COVID-19
American Society for Microbiology (ASM)

The measles-mumps-rubella (MMR) vaccine has been theorized to provide protection against COVID-19.

Released: 20-Nov-2020 10:40 AM EST
Study: TB Vaccine Linked to Lower Risk of Contracting COVID-19
Cedars-Sinai

A widely used tuberculosis vaccine is associated with reduced likelihood of contracting COVID-19 (coronavirus), according to a new study by Cedars-Sinai. The findings raise the possibility that a vaccine already approved by the U.S. Food and Drug Administration may help prevent coronavirus infections or reduce severity of the disease.

Released: 19-Nov-2020 2:45 PM EST
The Lancet: Phase 2 trial of Oxford COVID-19 vaccine in healthy older adults finds it is safe and provokes immune response
Lancet

Older adults are at a disproportionate risk of severe COVID-19 disease, so it is essential that any vaccine adopted for use against SARS-CoV-2 is effective in this group

17-Nov-2020 1:00 PM EST
Experts Issue Recommendations for Equitable Distribution of COVID-19 Vaccine
Children's Hospital of Philadelphia

A group of vaccine experts led by Children’s Hospital of Philadelphia (CHOP) has published recommendations to ensure equitable distribution of a COVID-19 vaccine when it becomes available. The framework, published today in Heath Affairs, focuses on five principles the authors believe would strengthen the current immunization delivery system to ensure equitable access to everyone for whom vaccination is recommended.

Released: 19-Nov-2020 9:00 AM EST
Global foundation awards Texas Biomed $1 million to conduct large-scale rodent testing of human monoclonal antibodies to combat SARS-CoV-2
Texas Biomedical Research Institute

Texas Biomedical Research Institute (Texas Biomed) in San Antonio, Texas, was awarded $1 million from the Bill & Melinda Gates Foundation to test the efficacy of human monoclonal antibodies (MAbs) for the treatment of SARS-CoV-2 infection. MAbs are human-made proteins meant to mimic human immune system antibodies. Texas Biomed Professors Luis Martinez-Sobrido, Ph.D. and Jordi B. Torrelles, Ph.D. will co-lead the project to evaluate the protective efficacy of these MAbs in small rodent models, developed at Texas Biomed, on behalf of the Coronavirus Immunotherapy Consortium (CoVIC), an international nonprofit consortium evaluating MAb therapeutics for COVID-19.

   
Released: 17-Nov-2020 2:55 PM EST
Rutgers Begins Recruiting Participants for Johnson & Johnson Phase 3 COVID-19 Vaccine Clinical Trial
Rutgers University-New Brunswick

Rutgers University is a clinical trial site for the Janssen Pharmaceutical Companies of Johnson & Johnson’s phase 3 clinical research study to evaluate the safety and efficacy of Janssen’s COVID-19 vaccine candidate.

Released: 17-Nov-2020 8:20 AM EST
Dr. Anthony Fauci to Speak at UVA Medical Center Hour
University of Virginia Health System

Anthony S. Fauci, MD, will discuss COVID-19 – including the latest on potential vaccines – in a free Zoom presentation at noon Nov. 18 during Medical Center Hour at the University of Virginia School of Medicine.

   
Released: 16-Nov-2020 11:00 AM EST
Measles outbreaks likely in wake of COVID-19 pandemic
Murdoch Childrens Research Institute

Major measles outbreaks will likely occur during 2021 as an unexpected consequence of the COVID-19 pandemic, according to a new academic article.

13-Nov-2020 11:50 AM EST
Mount Sinai Researchers Discover How to Boost Efficacy of Vaccine Designed to Prevent Melanoma Recurrence
Mount Sinai Health System

A vaccine created to prevent the recurrence of the deadly skin cancer melanoma is about twice as effective when patients also receive two components that boost the number and effectiveness of immune system cells called dendritic cells, according to phase 2 clinical trial results published in Nature Cancer in November.

Released: 16-Nov-2020 9:55 AM EST
Younger Parents Less Likely to Vaccinate Their Children and Themselves Against COVID-19
Vanderbilt University Medical Center

Younger parents were much less likely than older parents to say they planned to vaccinate their children and themselves against COVID-19, according to a research letter published online in medRxiv by authors at the Vanderbilt University School of Medicine and Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine.

Released: 12-Nov-2020 11:20 AM EST
Same storm, different boats: a reflection on COVID-19 models
University of Sydney

In March 2020, as the pandemic was sweeping the globe and establishing roots in Australia, the Complex Systems Centre at the University of Sydney modelled how varying rates of social distancing could affect the spread of the COVID-19 pandemic across a very diverse Australian population.

   
Released: 12-Nov-2020 9:00 AM EST
What We Know: Mount Sinai to Host COVID-19 Research Symposium
Mount Sinai Health System

The COVID-19 Research Symposium, hosted by the Mount Sinai Clinical Intelligence Center (MSCIC), is a one-day comprehensive review of advances in research by the Mount Sinai Health System to better understand and treat the coronavirus known as COVID-19.

Released: 11-Nov-2020 4:45 PM EST
MTU, UMass researchers preserve viral vaccines without refrigeration
Michigan Technological University

Half of vaccines are wasted annually because they aren’t kept cold. Michigan Tech and UMass Amherst chemical engineers have discovered a way to stabilize viruses in vaccines with proteins instead of temperature.

   
Released: 11-Nov-2020 8:00 AM EST
‘Pinprick’ biomarker blood test offers diagnostic potential in HPV-related cancers Study shows rising antibody levels predict the course of cancer
Abviris

A potential breakthrough in the early detection of the neck, head and anal cancers linked to human papilloma viruses (HPV) has emerged. It is based on a highly specific diagnostic test that appears to indicate cancer, and predict its course, from just a pinprick of blood.

Released: 10-Nov-2020 4:45 PM EST
FSU expert available to discuss COVID-19 vaccine development
Florida State University

Published: November 10, 2020 | 3:47 pm | SHARE: There may be good news on the horizon regarding a COVID-19 vaccine.Pfizer and partner BioNTech reported that their trial vaccine appears to have a 90 percent efficacy rate, meaning that test subjects who received a vaccine experienced 90 percent fewer cases of symptomatic COVID-19 than those who received a placebo.

Released: 10-Nov-2020 11:30 AM EST
Recommendations for fair and regulated access to a COVID-19 vaccine
Leopoldina

The first COVID-19 vaccines could be authorised as early as the start of 2021.

Released: 9-Nov-2020 3:15 PM EST
NIH Awards $2.9 Million Grant to Wake Forest Baptist Scientists to Develop Flu Vaccine for Newborns Using Animal Model
Atrium Health Wake Forest Baptist

Newborns and young infants are particularly susceptible to the flu and are six times more likely to die from the infection than older children. Currently there is no flu vaccine available for babies less than 6 months old.

Released: 5-Nov-2020 12:05 PM EST
University Hospitals Announces its Participation in Novel Clinical Trial Testing Multiple Therapeutics to Treat COVID-19
University Hospitals Cleveland Medical Center

ACTIV-2 will evaluate the safety and efficacy of investigational treatments for adults who have COVID-19, but do not require hospitalization. ACTIV-2 is a randomized, blinded, controlled study that tests a variety of new agents against placebo. This approach allows promising investigational agents to be added and removed over the course of the study.

30-Oct-2020 1:35 PM EDT
Fighting Zika? Call in the T cells
La Jolla Institute for Immunology

In a new Science Advances study, Shresta and her colleagues at LJI report that the immune system's T cells have the power to prevent Zika infection in mice. This finding suggests that effective Zika vaccines need to activate T cells to work alongside antibodies.

Released: 4-Nov-2020 1:20 PM EST
Key populations for early COVID-19 immunization in Canada
Canadian Medical Association (CMA)

Canada's National Advisory Committee on Immunization (NACI) recommends vaccinating key populations, such as people at risk of severe illness or death, those at risk of transmitting the virus and essential workers, during the initial rollout of a COVID-19 vaccine in Canada.

Released: 3-Nov-2020 3:30 PM EST
Iowa awards $2 million CARES Act grant to universities to study COVID-19 nanovaccine
Iowa State University

The state of Iowa has designated $2 million in federal CARES Act funding to support university research and development of a nanovaccine to protect against COVID-19 infections. Researchers at Iowa State University and the University of Iowa will work together on a needle-free, single-dose nanovaccine.

   
Released: 2-Nov-2020 3:55 PM EST
Researchers seeking volunteers for COVID-19 vaccine study
University of Texas Health Science Center at Houston

A Phase III clinical trial to assess if a potential vaccine is effective at preventing symptomatic COVID-19 is now open for enrollment by The University of Texas Health Science Center at Houston (UTHealth) in collaboration with Memorial Hermann-Texas Medical Center.

2-Nov-2020 3:00 PM EST
University of Chicago Medicine begins recruiting participants for phase 3 COVID-19 investigational vaccine clinical trial
University of Chicago Medical Center

The University of Chicago Medical Center will be a testing site for the Janssen Pharmaceutical Companies of Johnson & Johnson’s Phase 3 clinical research study, ENSEMBLE trial, to evaluate the safety and efficacy of the Janssen’s investigational COVID-19 vaccine candidate, JNJ-78436735, also known as Ad26.COV2.S.

Released: 30-Oct-2020 5:35 PM EDT
Surgeon General expects COVID-19 vaccine to be available by year’s end
University of California, Los Angeles (UCLA), Health Sciences

In a wide-ranging talk with UCLA Health physicians, Wednesday, Oct. 28, United States Surgeon General Jerome Adams, MD, MPH, addressed the politicization of the pandemic and the means of containing the spread of COVID-19. He also offered hope that a vaccine for the virus will be available by year’s end.

Released: 30-Oct-2020 4:05 PM EDT
ICE detention centers saw sustained outbreaks of vaccine-preventable diseases, says study
University of California, San Francisco (UCSF)

More than a dozen U.S. Immigration and Customs Enforcement (ICE) detention centers experienced large, repeated outbreaks of vaccine-preventable illnesses in the last three years, according to a new study by researchers at UC San Francisco.

   
Released: 30-Oct-2020 11:55 AM EDT
Wistar Creates a New Synthetic DNA Vaccine Against Powassan Virus
Wistar Institute

Wistar scientists have designed and tested the first-of-its-kind synthetic DNA vaccine against Powassan virus (POWV), targeting portions of the virus envelope protein.

   
Released: 29-Oct-2020 10:05 AM EDT
UH and CWRU Announce Study of AstraZeneca’s COVID-19 Vaccine Candidate
University Hospitals Cleveland Medical Center

University Hospitals and Case Western Reserve University announcement that UH Cleveland Medical Center has been selected as a clinical trial site for the Phase 3 global study of an investigational vaccine against SARS-CoV-2, sponsored by AstraZeneca (LSE/STO/NYSE: AZN).

Released: 28-Oct-2020 4:00 PM EDT
Investigator on the AstraZeneca vaccine trial will take questions at Live Event on Oct. 29, 3PM
Keck Medicine of USC

Dr. Edward Jones-Lopez, joins a Newswise Live Expert Panel on Thursday Oct. 29, from 3-4 PM EDT to discuss the AstraZenea COVID-19 vaccine trial.

Released: 28-Oct-2020 3:55 PM EDT
Sociology professors publish research on vaccine refusal
Creighton University

Study examines “personal belief exemptions” (PBEs) to childhood vaccine requirements among certain communities in California.

Released: 28-Oct-2020 12:45 PM EDT
COVID-19 vaccine nationalism could cost world up to $1.2 trillion: New RAND Europe study
RAND Corporation

Nationalistic behaviour by governments may exclude some countries from gaining access to COVID-19 vaccines and cost the global economy up to $1.2 trillion a year in GDP, according to a new study from the not-for-profit research organisation RAND Europe.

Released: 28-Oct-2020 10:35 AM EDT
New Johns Hopkins Center for Research on COVID-19 Immunity
Johns Hopkins Bloomberg School of Public Health

Researchers at the Johns Hopkins Bloomberg School of Public Health and Johns Hopkins University School of Medicine have been jointly awarded a major grant from the National Cancer Institute, part of the National Institutes of Health, to set up a center for research on the human serological immune response to SARS-CoV-2, the coronavirus that causes COVID-19.

Released: 28-Oct-2020 8:55 AM EDT
Study: Turning a coronavirus protein into a nanoparticle could be key to an effective COVID-19 vaccine
University at Buffalo

One of the proteins on the virus – located on the characteristic COVID spike – has a component called the receptor-binding domain, or RBD, which is its “Achilles heel.” That is, he said, antibodies against this part of the virus have the potential to the neutralize the virus.

Released: 22-Oct-2020 1:50 PM EDT
UNLV Physician: Why COVID-19 Makes Flu Shots More Important Than Ever
University of Nevada, Las Vegas (UNLV)

As the race for a COVID-19 vaccine intensifies, health care officials are reminding the public not to forget another important vaccine this fall: the flu shot. Flu season in the U.S. technically began in September, with illnesses expected to peak in December and February, according to the Centers for Disease Control (CDC). Less than half of Americans received a flu vaccine during the 2019-2020 flu season, and a staggering 405,000 hospitalizations and 22,000 deaths were attributed to influenza.

Released: 22-Oct-2020 11:55 AM EDT
Key details about broadly neutralizing antibodies provide insights for universal flu vaccine
University of Chicago Medical Center

New research from an immunology team at the University of Chicago may shed light on the challenges of developing a universal flu vaccine that would provide long-lasting and broad protection against influenza viruses.

Released: 22-Oct-2020 8:05 AM EDT
Your guide to a COVID-19 vaccine: What the public needs to know
Keck Medicine of USC

Edward Jones-Lopez, MD, MS, a Keck Medicine of USC infectious diseases expert and investigator of one of the Operation Warp Speed vaccine clinical trials, answers the questions on everyone’s mind.

Released: 21-Oct-2020 12:50 PM EDT
Rutgers Pediatricians Sound Alarm on Decreased Flu Vaccinations, Immunizations for Children
Rutgers University-New Brunswick

Two Rutgers New Jersey Medical School pediatricians discuss the importance of keeping children and adults up to date with immunizations during the coronavirus crisis.

   
Released: 21-Oct-2020 10:40 AM EDT
Vaccines and rare diseases: using one to help the other
Universite de Montreal

An immunology researcher in Canada has found a simple solution to prevent infections in children with lactic acidosis: get them vaccinated.



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