While developing an important cancer drug, Wistar scientists discovered that mice without the TRAP-1 protein live healthier longer lives, with fewer tumors and signs of aging.
AMP today reaffirmed its position that the vast majority of laboratory developed procedures should continue operating under the regulation of the CLIA program at the CMS and not be subject to pre-market review by the FDA, as suggested in the draft guidance notification issued to Congress on July 31, 2014.
A team of Whitehead Institute researchers is bringing new levels of efficiency and accuracy to one of the most essential albeit tedious tasks of bench science: pipetting. Dubbed “iPipet,” the system converts an iPad or any tablet computer into a “smart bench” that guides the execution of complex pipetting protocols.
A team of scientists in Israel and Germany have created robots that are only nanometers in length, small enough to maneuver inside the human body and possibly inside human cells.
Bee, snake or scorpion venom could form the basis of a new generation of cancer-fighting drugs, scientists will report here today. They have devised a method for targeting venom proteins specifically to malignant cells while sparing healthy ones, reduces or eliminates side effects that the toxins would otherwise cause. Their study is part of the 248th National Meeting of the American Chemical Society, the world’s largest scientific society.
The Kavli Foundation Lecture series features two prominent scientists: one in the booming area of ionic liquids, the other in medical materials. The former has made a novel compound with the potential to lower the energy it takes to capture carbon dioxide. The latter has engineered tissues and medical materials such as a stretchy glue that could transform surgery. They are presenting at the 248th National Meeting & Exposition of the American Chemical Society.
Cyborg technology is bringing us real-life electronic skin, prosthetics and ultra-flexible circuits. Now taking this human-machine concept to an unprecedented level, pioneering scientists are working on the seamless marriage between electronics and brain signaling with the potential to transform our understanding of how the brain works — and how to treat its most devastating diseases. Their presentation is taking place at the 248th National Meeting & Exposition of the American Chemical Society.
With nothing more than a smartphone and less than $10 of trinkets and hardware supplies, students at Missouri University of Science and Technology can build their own microscopes this fall as part of a biology lab.
As one of the 10 largest medical exhibitions in the U.S., the 2014 AACC Annual Meeting & Clinical Lab Expo is the place where breakthrough innovations in clinical testing and patient care are introduced to the healthcare world. This year, many of the trailblazing products displayed by the Expo’s 650 exhibitors will include the latest diagnostic technology in the field of mobile health.
Robotic conference offers instruction to assist trained surgeons expand their minimally invasive surgical techniques.
The groundbreaking scientific studies featured at the 2014 AACC Annual Meeting & Clinical Lab Expo will include research on a blood test for Alzheimer’s that uses biochip technology, a new test to diagnose colon cancer early, a more accurate method for determining multiple myeloma prognosis, a less stressful test for sleep apnea, and the development of a bank of biospecimens from pregnant women that could prove crucial for women’s health research.
Researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center are exploring ways to wake up the immune system so it recognizes and attacks invading cancer cells. One pioneering approach uses nanoparticles to jumpstart the body’s ability to fight tumors
COLA, the largest private accreditor of medical laboratories serving more than 8,000 across the U.S., successfully concluded its 2014 Leadership Summit in April. More than 30 thought leaders in health care, including physicians, regulators, public health experts, medical laboratory scientists, manufacturers, nurse practitioners and more gathered in San Francisco to discuss the future of laboratory medicine in the context of the Affordable Care Act (ACA). The group explored the implications of the dynamics of ACA and changing payment policies on quality and learning in laboratory medicine.
The nation’s healthcare system -- and with it, the laboratory community – is undergoing a period of tremendous change as The Affordable Care Act begins implementation and new healthcare delivery models such as The Patient-Centered Medical Home (PCMH) and Accountable Care Organizations (ACOs) proliferate. With more than 70 percent of medical decisions based on lab data, laboratories are emerging as vital partners of these new healthcare teams. Labs are uniquely qualified to use the patient data they capture to provide feedback to allied health professionals that can increase efficiency and contain health-care costs while improving patient care.
COLA Inc., based in Columbia, MD, an independent, nonprofit laboratory CLIA-accreditation organization, accrediting more than 7,000 clinical diagnostic labs on July, 2013, launched a new education subsidiary, COLA Resources Inc. (CRI®), whose mission is to “Provide educational & consultative services aimed at improving laboratory medicine and patient care.”
Diazyme Laboratories today announced that the U.S. Food and Drug Administration (FDA) has granted 510(K) clearance to market its Vitamin D assay for Clinical Chemistry Analyzers. In line with the rapid increasing clinical demands for testing of this important biomarker, Diazyme’s new Vitamin D assay, utilizing its femtoquantTM technology (a sensitive homogenous enzyme-immunoassay platform), provides the first fully automated Vitamin D test for use on general clinical chemistry analyzers. Diazyme’s Vitamin D assay measures total 25-hydroxy Vitamin D (sum of 25-(OH)D3 + 25-(OH)D2 ) levels.
Applied and effortless simplicity of Burkert products have always been something to rely on – now we have added pure flexibility to the list of standards you can expect. The unique Pneumatic Dosing unit from Burkert – ultra precision and repeatability of fluid dosing come together with a flexible, customizable design giving you precisely the results that matter to you. Whether your world is dosing pharma media or syrup, vaccines or coffee flavors, wide ranging performance just met your changing needs.
As a leading educator in laboratory medicine, COLA Resources Inc.’s (CRI®) goal is to continually update our education platform to reflect and support education regarding changes in regulatory requirements. The most recent regulatory changes impacting the clinical laboratory is the Centers for Medicare and Medicaid Services (CMS) new Individualized Quality Control Plan (IQCP) quality control interpretive guidelines. CRI®’s IQCP program is designed to assist clinical laboratories develop and implement their own individualized quality control. The program contains an innovative and intuitive software program IQCP E-Optimizer™ and an IQCP Implementation Guide.
Attending the CRI® Symposium for Clinical Laboratories, affords participants the opportunity to participate in discussions centered on EDUCATION FOR LABORATORY EXCELLENCE – making a positive impact for quality patient care. This year’s symposium will be held October 15-18, 2014 at the Buena Vista Palace Hotel & Spa Lake Buena Vista (Orlando), FL. Participants can attend a wide selection of educational sessions, earn up to 20 CME or P.A.C.E® credits, network with other healthcare professionals and visit the exhibit hall featuring the latest laboratory technology, equipment and supplies.
A partnership born out of the URI Institute for Immunology and Informatics has resulted in a new web-based tool designed to help manufacturers of protein-based therapeutics improve the safety of their manufacturing processes, avoiding problems that caused the U.S. Food and Drug Administration to suspend a clinical trial in 2012.
Whitehead Institute scientists have genetically and enzymatically modified red blood cells to carry a range of valuable payloads—from drugs, to vaccines, to imaging agents—for delivery to specific sites throughout the body.
Using a type of human stem cell, Johns Hopkins researchers say they have created a three-dimensional complement of human retinal tissue in the laboratory, which notably includes functioning photoreceptor cells capable of responding to light, the first step in the process of converting it into visual images.
When stem cells are used to regenerate bone tissue, many wind up migrating away from the repair site, which disrupts the healing process. But a University of Rochester research team makes use of a technique that keeps the stem cells in place, resulting in faster and better tissue regeneration.
A team led by researchers at The Scripps Research Institute has used advanced electron microscopy techniques to determine the first accurate structural map of Mediator, one of the largest and most complex “molecular machines” in cells.
A clearer understanding of how mussels stick to surfaces could lead to new classes of adhesives that will work underwater and even inside the body.
UNC School of Medicine researchers have provided the first quantitative evidence that mucins – the protein framework of mucus – are significantly increased in cystic fibrosis patients and play a major role in failing lung function.
Collaboration Combined with Revolutionary Technology opens new potential to identify new biomarkers and therapeutic points of intervention for use in the development of new Alzheimer’s treatments
Researchers at The University of Texas MD Anderson Cancer Center and other institutions have applied a newly developed software tool to identify genetic mutations that contribute to a person’s increased risk for developing common, complex diseases, such as cancer.
Scientists have developed a powerful tool called pVAAST that combines linkage analysis with case control association to identify disease-causing mutations in families faster and more precisely than ever before.
A new technology under development at the Georgia Institute of Technology could one day provide more efficient delivery of the bone regenerating growth factors with greater accuracy and at a lower cost.
Protea Biosciences Group, Inc. (OTCQB:PRGB) announced it has entered into a research collaboration with the University of Southampton, a leading biomedical and clinical research institution located in the United Kingdom. The collaboration will partner Protea’s proprietary direct molecular imaging technology and capabilities with a team of Alzheimer’s researchers at the University of Southampton, to study the molecular mechanisms of the aged brain, in order to identify markers that may indicate risk of developing Alzheimer’s disease.
A paper from University of Alabama at Birmingham researchers in the journal Science about the fertility of roundworms may have implications for everything from captive pandas to infertile couples struggling to conceive.
Mice severely disabled by a condition similar to multiple sclerosis (MS) were able to walk less than two weeks following treatment with human neural stem cells. The finding, which uncovers potential new avenues for treating MS, will be published online on May 15, 2014, in the journal Stem Cell Reports.
Feeling sluggish? Gaining weight? What you need is a shot in the arm, claim advertisers for trendy vitamin B12 injections.Don’t let marketers needle you.“If medical testing confirms that an individual has a vitamin B12 deficiency, a vitamin B12 supplement will help. But if a B12 deficiency has not been identified by a physician or primary care doctor, there is no need to waste energy and money on B12 shots,” says Ashley Barrient, clinical dietitian, Loyola Center for Metabolic Surgery & Bariatric Care.
Ram Sasisekharan’s startups provide novel methods to fight disease and make better drugs.
Researchers from MIT’s Koch Institute, the Broad Institute, and the Dana-Farber Cancer Institute come together to overcome the barriers to sequencing circulating tumor cells.
Chang Lu of Virginia Tech’s Chemical Engineering Department has developed techniques that allow him to obtain reliable results over the course of disease development inside cells. The National Institutes of Health is a past supporter of this work, and just announced a new $1.3 million grant to further this work.
Newswise hosts the first live, interactive virtual event for major research finding for journalists. Newswise and Wake Forest Baptist Medical Center are collaborating to offer direct access to the investigator via Newswise Live, an interactive virtual event.
Long-term results are reported for the first patients to receive laboratory-engineered vaginal organs.
As one of the most widely consumed and commercially important beverages on the planet, one would expect the experts to know everything there is to know about lager beer. Now, however, scientists are beginning to color in the margins of yeast ecology and genetics, identifying new strains in new environments and using the tools of molecular biology to ferret out traits that could aid industrial fermentation technologies.
A biomedical engineering breakthrough could speed soft tissue injury recovery and limit disfigurement from radical cancer surgeries. It could circumvent the need to harvest and transfer large amounts of tissue, avoiding many current complications.
From time to time, living cells will accidentally make an extra copy of a gene during the normal replication process. Throughout the history of life, evolution has molded some of these seemingly superfluous genes into a source of genetic novelty, adaptation and diversity. A new study shows one way that some duplicate genes could have long-ago escaped elimination from the genome, leading to the genetic innovation seen in modern life.
University of California, San Diego bioengineer Karen Christman's new injectable hydrogel, which is designed to repair damaged cardiac tissue following a heart attack, has been licensed to San Diego-based startup Ventrix, Inc, which is planning the first human clinical trials of the technology. Christman is a co-founder of Ventrix.
A look back at how Institute Professor Phillip Sharp, his startup Biogen, and MIT’s biotech community helped revive Kendall Square
Tweaking a specific cell type’s ability to absorb potassium in the brain improved walking and prolonged survival in a mouse model of Huntington’s disease, reports a UCLA study in Nature Neuroscience. The discovery could point to new drug targets for treating the devastating disease, which strikes one in every 20,000 Americans.
Scientists at the Center for Nanotechnology and Nanotoxicology at Harvard School of Public Health have discovered a way to measure the effective density of engineered nanoparticles in physiological fluids, making it possible to determine the amount of nanomaterials that come into contact with cells and tissue in culture.
Narine Sarvazyan, Ph.D., professor of pharmacology and physiology at the George Washington University School of Medicine and Health Sciences, has invented a new organ to help return blood flow from veins lacking functional valves.
As stem cells continue their gradual transition from the lab to the clinic, a research group at the University of Wisconsin-Madison has discovered a new way to make large concentrations of skeletal muscle cells and muscle progenitors from human stem cells.
A new kind of single-dose vaccine that comes in a nasal spray and doesn’t require refrigeration could dramatically alter the public health landscape — get more people vaccinated around the world and address the looming threats of emerging and re-emerging diseases. Researchers presented the latest design and testing of these “nanovaccines” at the 247th National Meeting & Exposition of the American Chemical Society (ACS), the world’s largest scientific society.
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