Heating proteins to body temperature reveals new drug targets
Van Andel InstituteSome proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications.
Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications.
The medical director of New Jersey Poison Control at Rutgers University discussed how adults and children can safely take over the counter seasonal allergy medication.
PNNL researchers learn to control peptoid “handedness,” one key to precision drug delivery and diagnostics.
NeuroTherapia, an early-stage clinical pharmaceutical company, announced today that it has received a grant from the Alzheimer's Association Part the Cloud program for the development of its first-in-class drug, NTRX-07, for the treatment of Alzheimer's disease (AD).
Researchers at the UNC Eshelman School of Pharmacy and the UNC School of Medicine have engineered a probiotic yeast that enhances probiotic absorption in the gut and has the ability to suppress and even reverse inflammation in animals.
Researchers from University of California San Diego have developed a new AI tool to that generate new drug candidates for cancer, which could help streamline the typically laborious drug discovery process.
For most smokers, quitting on the first attempt is likely to be unsuccessful, but a new study from The University of Texas MD Anderson Cancer Center found patients were more likely to quit if their cessation regimen was altered and doses were increased. Researchers also found that varenicline, a cessation medication, was more effective than combined nicotine replacement therapy (CNRT), such as patches or lozenges.
Viruses known as “jumbo” phages are seen as a potential tool against deadly bacterial infections. But scientists must first decipher the extraordinary makeup of these mysterious viruses. Researchers have now uncovered a key piece of jumbo phage development that helps them counter bacteria.
Children’s Hospital Los Angeles is offering families an opportunity to eliminate the danger of unwanted medications in their home by disposing of their unwanted pills safely, responsibly and permanently.
The American Society for Pharmacology and Experimental Therapeutics (ASPET) and Elsevier, a global leader in information and analytics, are partnering to publish the Society’s four journals.
Binghamton University, State University of New York has approved a new program through the School of Pharmacy and Pharmaceutical Sciences. The Pharmacy Technician Program Microcredential is a 19-week, 420-hour Binghamton University Microcredential (noncredit) that will prepare graduates to start their career confidently in an expanding healthcare field.
New study by UC Davis researchers shows how pharmacies may provide crucial access to tobacco cessation tools that help people successfully quit smoking.
America is going the wrong way when it comes to prescribing antibiotics, with 1 in 4 prescriptions going to patients who have conditions that the drugs won’t touch, a new study finds.
Digital Science solutions metaphacts and Dimensions announce the launch of the Dimensions Knowledge Graph, a large ready-made knowledge graph powering AI solutions in the pharmaceutical and life sciences industries.
The bitter taste of certain drugs is a barrier to taking some medications as prescribed, especially for people who are particularly sensitive to bitter taste. A Monell team found that the diabetes drug rosiglitazone could partially block the bitter taste of some especially bad-tasting medications.
Recent work by St. Jude Children’s Research Hospital scientists discovered which tumor cells resist treatment and why. By characterizing B-cells’ developmental stages, they designed and tested a drug combination to effectively treat resistant B-cell leukemia.
Researchers have developed an automated workflow that could accelerate the discovery of new pharmaceutical drugs and other useful products. The new approach could enable real-time reaction analysis and identify new chemical-reaction products much faster than current laboratory methods.
The common painkiller acetaminophen was found to alter proteins in the heart tissue when used regularly at moderate doses, according to a new study conducted in mice. Researchers will present their work this week at the American Physiology Summit in Long Beach, California.
Pharmacists are being recognised for their vital role in supporting home-based rural palliative care patients, as new research shows that they not only enable patients to choose to stay at home, but also provide significant relief, comfort, and peace of mind for patients, carers, and family members.
SARS-CoV-2 will eventually become resistant to the only effective oral treatment. The world needs another.
Cystic fibrosis is the most common, life-limiting genetic condition in Australia. It affects the lungs, digestive system, and reproductive system, producing excess mucus, infections, and blockages.
University of Maryland School of Medicine (UMSOM) Dean Mark T. Gladwin, MD, announced today that Martine Rothblatt PhD, JD, MBA, Chairperson and CEO of United Therapeutics, and inventor of SiriusXM Satellite Radio, will deliver the keynote address for this year’s graduating medical student class. The UMSOM MD graduation ceremony will take place at the Hippodrome Theatre on Thursday, May 16, 2024.
Nucleus Genomics, the next-generation genetic testing and analysis company, today announced the launch of its DNA analysis product to bring the benefits of personalized medicine to everyone.
A team of scientists led by Prof Guillermo Bazan from NUS Institute for Functional Intelligent Materials (I-FIM) has developed a novel antibiotic named COE-PNH2 that is capable of combating hard-to-treat mycobacterial lung infections.
Scientists report they have extracted a compound with powerful antibacterial properties from the skin of farmed African catfish.
A newly developed compound is showing promise in animal studies as a more effective treatment for human schistosomiasis, an understudied tropical disease caused by parasitic worms.
An artificial intelligence tool West Virginia University health data scientists are developing could lessen medication errors that send recently discharged patients back to the hospital while reducing health care costs.
“Today, we at the Association for Diagnostics & Laboratory Medicine (ADLM, formerly AACC) provided testimony to Congress regarding the impact of the Food and Drug Administration’s (FDA’s) proposed rule to impose FDA oversight on laboratory developed tests in addition to Centers for Medicare & Medicaid Services (CMS) oversight. While we share FDA’s goal of ensuring that laboratory developed tests are safe and effective, we have serious concerns about the agency’s proposal. If finalized, this rule would create a burdensome dual regulatory structure that would limit patient access to many life-saving tests.
Kazia Therapeutics Limited (NASDAQ: KZIA), a biotechnology company specialising in oncology, is pleased to announce that it has entered into an exclusive licensing agreement with Sovargen Co., Ltd, a biotechnology company specializing in central nervous system (CNS) diseases, to develop, manufacture and commercialise paxalisib as a potential treatment of intractable epilepsy in focal cortical dysplasia type 2 (FCD T2) and tuberous sclerosis complex (TSC) disease.
ScienceMedia, a global SaaS provider redefining the landscape of clinical mastery in the biotech and pharma industries, announces the formation of its inaugural advisory board.
The use of vitamin supplements is on the rise in the U.S. But do they do any good? A Penn State Health expert talks about the benefits and pitfalls.
Prostate cancer patients receiving care at hospitals that are part of a special drug-pricing program were more likely to stick to their prescription drug therapy than patients at other hospitals, according to a study from researchers at the University of Michigan’s Rogel Cancer Center and Institute for Healthcare Policy and Innovation.
The collaboration between Philadelphia College of Osteopathic Medicine (PCOM) and The Wistar Institute has resulted in the creation of a PhD program in Cancer Biology, preparing individuals for careers in cancer research and drug development.
Teardrop-shaped particles designed to inactivate multiple strains of the SARS-CoV-2 virus could one day complement existing treatments for COVID-19, according to a new study led by researchers at the University of Michigan and Jiangnan University in Wuxi, China.
A global wave of infections caused by fungi growing drug-resistant has the medical community issuing precautions on how to protect yourself.
Radyus Research partners with Southern Research for an innovative alliance in the development of new drugs.
An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk.
In a new study, Sanford Burnham Prebys researchers, led by Andrei L. Osterman, Ph.D., combined experimental evolution in a continuous culturing device with whole genome sequencing of evolving cultures to track how two bacterial pathogens acquired drug resistance against a pair of antibiotics, one long-used and the other experimental.
Nine scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $13 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support research and prevention efforts on a wide range of cancer issues. UTSW received another $6 million for recruitment efforts.
New research shows HIV medications can be taken at the same time as hormone treatment without losing potency of either therapy.