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A new company spawned by McMaster University innovation in the arena of vaccine manufacturing has received a grant from the Bill & Melinda Gates Foundation. Elarex Inc., based in Burlington, has been awarded a $1.2M Cdn grant from the non-profit humanitarian foundation to develop a new technology for keeping liquid mRNA vaccines safe and viable without the deep-freeze that is necessary today for storing and transporting such vaccines.
Immunologist David A. Ostrov, Ph.D., was asked by a worldwide consortium of scientists to analyze and map the locations of omicron’s mutations. His analysis for the Global Virus Network found omicron has substantially more mutations than the delta variant at four key sites within the virus.
Mayo Clinic experts say, regardless of the variant, prevention of infection works. The vaccines reduce and prevent hospitalization and death based on current knowledge. If a person can get vaccinated or is eligible for a booster, do it now. But what about these variants? Why do they show up, and how? Here is what Mayo Clinic experts are saying:
The combination of two monoclonal antibodies, called Evusheld, was authorized as a pre-exposure prophylaxis to prevent COVID-19 in adults and children 12 years and older who have compromised immune systems or a history of severe adverse reactions to a COVID-19 vaccine.
Many parents have been concerned about reports of myocarditis—heart inflammation—in some young people who have received a COVID-19 vaccine. This worry is understandable. But there’s also reassuring news: Heart inflammation after the vaccine is a very rare event.
Antibodies against the SARS-CoV-2 spike protein produced by the immune system can help identify and fend off future infections, but not all antibodies are the same.
Rush physicians and scientists can explain how SARS-CoV-2 is studied through weekly genomic sequencing, how it has changed over time and how that knowledge can be applied to such concerns as outbreaks, breakthrough cases and the arrival of new variants.
A combination of vaccination and naturally acquired infection appears to boost the production of maximally potent antibodies against the COVID-19 virus, new UCLA research finds.
The study, called COVID CommUNITY- First Nations, will collect, analyze, and report data relating to COVID-19 vaccine effectiveness and safety, as well as explore hesitancy in three First Nations communities in Canada: Six Nations of the Grand River in southwestern Ontario; Lac La Ronge Indian Band in Saskatchewan; and Wendake in Quebec.
Human trials are set to begin for two next-generation COVID-19 vaccines developed by a team of scientists at McMaster University.
According to a new study by researchers at the University of Illinois Chicago, approximately 3 in 20 health care workers surveyed reported being hesitant about getting their COVID-19 vaccinations. The study also showed workers’ vaccine decisions were likely to be influenced by their colleagues.
As the first cases of flu are reported in Los Angeles this season, public health experts are urging anyone who isn't already vaccinated to get the flu shot. It's the best protection against the flu, which could pummel the U.S. this winter after nearly disappearing last year.
Boys are 10 times more likely to be vaccinated against human papillomavirus (HPV) in provinces where the vaccine is publicly funded than in places where it is not, according to a new study published by a researcher at the Princess Margaret Cancer Centre and colleagues at McGill University, Université de Montréal, and the Jewish General Hospital.
Kim Iversen, a popular political talk show host with over 27K followers on Twitter, claimed that people who are fully vaccinated against COVID-19 are global superspreaders of the new omicron variant. “I can’t believe that after fully vaccinated travelers have been found to be the global spreaders of the omicron variant, we’re STILL talking about forcing people into being vaccinated,” she wrote on Twitter. We find this claim to be misleading. There is very little data on how the new variant is being spread.
Hackensack Meridian Health, New Jersey’s largest and most comprehensive health network, today announced a partnership with CLEAR (NYSE: YOU), the secure identity company, to empower patients with a digital proof of their COVID-19 vaccination records. Patients vaccinated at Hackensack Meridian Health can now use the free CLEAR app and digital vaccine card feature - replacing their fragile paper card with a verified digital version that can be used anywhere and anytime needed.
Scientists at La Jolla Institute for Immunology (LJI) and Massachusetts Institute of Technology (MIT), have found a possible way to improve the effectiveness of COVID-19 vaccines—and any vaccine.
November 18, 2021 – Chulalongkorn University held Chula The Impact 5 Seminar on “The Progress on ChulaCov19 — an mRNA vaccine by Thais — the World’s Hope“. Also discussed was the progress of Chula-Baiya, Thailand’s first protein subunit vaccine from tobacco leaves by Baiya Phytofarm Co., Ltd., and Faculty of Pharmaceutical Sciences, Chulalongkorn University.
A new opinion piece published online in the Annals of the American Thoracic Society provides an exhaustive examination of the ethics of using hospital resources on unvaccinated-by-choice COVID-19 pneumonia patients, versus patients with other serious illnesses whose diseases are not progressing as quickly.
New study models future SARS-CoV-2 mutations and forecasts their ability to evade immune defenses developed by vaccines and antibody-based treatments.
New research highlights the critical, continued role APS beamlines play in developing vaccines and therapeutics for COVID-19 and its variants.
Patients whose immune systems are weakened due to cancer, organ or bone marrow transplants, chronic diseases, or the medications used to treat these conditions may feel like they have enough on their plates without worrying about whether and when they should take an additional dose of COVID-19 vaccine and a flu shot.
Researchers at Moffitt Cancer Center are working to develop a dendritic cell vaccine targeting HER3, a protein involved in the growth and spread of many different cancer types. Their pre-clinical work has been published in the journal Cancer Immunology Research.
Kizzmekia S. Corbett, well known for her work on the mRNA vaccines used to protect against Covid-19, has been named the recipient of the 2021 E.E. Just Award by the ASCB.
Vaccine hesitancy is considered one of the top 10 threats to public health by the World Health Organization.
Dec. 1, 2021— People living with HIV experience more severe outcomes and have higher comorbidities from COVID-19 than people not living with HIV, according to the 2020 UNAIDS Global Update. In mid-2021, most people living with HIV did not have access to COVID-19 vaccines. This World AIDS Day, the Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a founding member, is calling on governments, health advocates and non-government organisations to strengthen their response to AIDS and COVID-19 by making COVID-19 vaccines more accessible worldwide.
UC San Diego nanoengineers developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells. Their approach involves packing mRNA inside nanoparticles that mimic the flu virus—a naturally efficient vehicle for delivering genetic material such as RNA inside cells.
Kaiser Permanente research in Southern California published Nov. 25, 2021, in The Lancet Regional Health – Americas confirmed high Moderna COVID-19 vaccine effectiveness up to 5 months after the second dose.
Rutgers, a clinical trial site for the global Pfizer-BioNTech research study to evaluate the efficacy of its COVID-19 vaccine in children, is looking for participants for a third clinical trial on children ages 6 months to 4 years.
A new article published in The New England Journal of Medicine suggests that secondary antibodies known as “anti-idiotype antibodies” could be responsible for some of the side effects of COVID-19 vaccines and the symptoms of long-haul COVID.
Individuals with kidney failure who were on dialysis had an incomplete and delayed antibody response and a blunted cellular immune response following COVID-19 vaccination, compared with people with normal kidney function.
A vaccine booster is readied for use.
A new study summarized in a research letter to be published in JAMA Pediatrics reveals that a number of factors, including negative impacts from the pandemic during pregnancy and reports of discrimination, made it less likely that infants received their recommended vaccinations in the first months of their lives.
While cases appear to have fallen in Uttar Pradesh as well as most locations in India, it’s not clear why. Many other factors, including immunity from a previous infection, vaccination, and lockdowns, likely helped reduce the number of cases.
The Institute for Molecular Medicine will advance the manufacturing of Duvax for the first clinical trials of a dual vaccine for Alzheimer's disease to begin in 2023
Cedars-Sinai physicians who have been on the front lines in the battle against COVID-19 in the community are also doing their part at home by getting their children vaccinated against the virus.
People taking TNF inhibitors, a kind of immunosuppressive drug used to treat rheumatoid arthritis and other autoimmune conditions, produced a weaker and shorter-lived antibody response after two doses of Pfizer's COVID-19 vaccine, according to a study from Washington University School of Medicine in St. Louis. A third vaccine dose drove antibody levels back up, indicating that this additional dose may provide protection as the virus's delta variant continues to spread.
As widely-anticipated decisions about COVID-19 vaccine boosters roll out from U.S. agencies today, insights from an independent study underscore why boosters are important for all adults.
A virtual workshop for users of the Advanced Photon Source and the Center for Nanoscale Materials highlighted pioneering research to understand the SARS-CoV-2 virus and its variants that cause COVID-19.
Researchers at Beth Israel Deaconess Medical Center (BIDMC) conducted a head-to-head test of the second-generation vaccine CV2CoV compared with CVnCoV. The scientists assessed the vaccines’ ability to provoke an immune response as well as their protective efficacy against COVID-19 in non-human primates.
Loyola Medicine is now offering the COVID-19 vaccine to children ages 5 to 11 at multiple clinic sites, including mobile vaccine clinics. The Pfizer COVID-19 vaccine was authorized for emergency use for children ages 5 to 11. It is a two-dose series taken three weeks apart. Each dose will be 1/3 the dosage of the adolescent/adult vaccine.
A randomized controlled trial of 2,275 women in Kenya showed that a single dose of the HPV vaccine was highly effective. The current standard for women is three doses. This news could greatly hasten the pace of vaccinations and brings renewed energy to make cervical cancer the first cancer to be wiped out.
Research by UCLA Fielding School's UCLA Center for Health Policy Research, led by Dr. Ninez Ponce, Fielding School professor of health policy and management, found that Californians have varied their COVID-19 risk reduction based on their test results
The CDC’s vaccine prioritization strategy performed well compared to other approaches, though with some room for improvement
Iowa State University researchers were part of a team evaluating possible strategies the CDC could have recommended last winter for COVID-19 vaccine rollouts.
Wealthier nations should pay a COVID-19 vaccine tax as part of the price they pay to manufacturers, to ensure a fairer distribution of the jab to poorer nations, argues a political scientist in the Journal of Medical Ethics.
ISPOR—The Professional Society for Health Economics and Outcomes Research (HEOR) announced its plenary speakers for Virtual ISPOR Europe 2021 scheduled for 30 November - 3 December.
A survey of parents and caregivers of children with cancer found that nearly a third of them expressed hesitancy to vaccinate their youngsters against COVID-19.
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