A compound found in common foods such as red grapes and peanuts may help prevent age-related decline in memory, according to new research published by a faculty member in the Texas A&M Health Science Center College of Medicine.
Columbia Engineering Professor Samuel Sia has developed a low-cost smartphone accessory that can perform a point-of-care test that simultaneously detects three infectious disease markers—HIV and syphilis—from a finger prick of blood in just 15 minutes. The device replicates, for the first time, all mechanical, optical, and electronic functions of a lab-based blood test without requiring any stored energy: all necessary power is drawn from the smartphone. February 4, Science Translational Medicine.
A new study by University of North Carolina at Chapel Hill researchers finds that a collection of simple strategies used by parents can lead to significant improvements in one-year-olds at risk for autism spectrum disorder (ASD).
Full implementation of new hypertension guidelines could prevent 56,000 cardiovascular disease events (mostly heart attacks and strokes) and 13,000 deaths each year, without increasing overall health care costs, an analysis conducted by researchers at Columbia University Medical Center found. The paper was published today in the online edition of the New England Journal of Medicine.
Women whose bodies have high levels of chemicals found in plastics, personal-care products, common household items and the environment experience menopause two to four years earlier than women with lower levels of these chemicals, according to a new study at Washington University School of Medicine in St. Louis. The findings are reported online Jan. 28 in the journal PLOS ONE.
According to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania, only 25 percent of women who had reported no earlier sleep problems developed moderate or severe insomnia or other sleep disturbances during a 16-year period around menopause. What’s more, the researchers say that these sleep woes did not appear to be caused by menopause itself, which may quell common fears about symptoms associated with this phase of life.
Psychopathic violent offenders have abnormalities in the parts of the brain related to learning from punishment, according to an MRI study led by Sheilagh Hodgins and Nigel Blackwood.
People who carry a variant of a gene that is associated with longevity also have larger volumes in a front part of the brain involved in planning and decision-making, according to researchers at UC San Francisco.
Researchers found that – when it comes to the ability to regulate emotions – brain activity in autistic people is significantly different than brain activity in people without autism. Researchers showed that symptoms including tantrums, irritability, and anxiety have a biological, mechanistic basis.
A new study shows that more than half the people in some developing countries could become newly at risk for malnutrition if crop-pollinating animals — like bees — continue to decline.
The female hormones estrogen and estradiol may help ward off the effects of lead exposure for young girls, explaining why boys, are shown to suffer more often from the cognitive disabilities linked to lead.
Pelizaeus Merzbacher disease, or PMD, is a devastating neurological condition that, in its most severe form, kills infants weeks after birth. Thirty years ago, UW-Madison neuroscientist Ian Duncan noticed a genetic mutation in dogs that was practically identical to the disease in humans. Now, in the online edition of the journal Neurobiology of Disease, Duncan has laid out the results of his marathon pursuit of PMD.
Scientists have identified a gene that helps regulate how well nerves of the central nervous system are insulated, researchers at Washington University School of Medicine in St. Louis report.
Classic psychedelic drugs include LSD, psilocybin and mescaline. This new School of Public Health research is published in the Journal of Psychopharmacology.
The amount of time a person sits during the day is associated with a higher risk of heart disease, diabetes, cancer, and death, regardless of regular exercise—
according to a review study published today in the Annals of Internal Medicine.
Recent scientific advances have meant that eyesight can be partially restored to those who previously would have been blind for life. However, scientists at the University of Montreal and the University of Trento have discovered that the rewiring of the senses that occurs in the brains of the long-term blind means that visual restoration may never be complete.
A new study by Dana-Farber Cancer Institute investigators demonstrates that vitamin D can protect some people with colorectal cancer by perking up the immune system’s vigilance against tumor cells.
The bacteria Vibrio vulnificus, found in warm saltwater, can cause people to get sick, or die, after they eat raw tainted shellfish or when an open wound comes in contact with seawater. A new UCLA study finds out not only why this potentially deadly bacteria is so dangerous in iron overload disease but also discovers that it can be cured.
Researchers at UT Southwestern Medical Center have identified hyaluronon (HA) as a critical substance made by the body that protects against premature births caused by infection.
Wearable technology allows 24-year-old with a total artificial heart to wait at home for a heart transplant. It's the latest milestone in efforts to replace the failing heart.
Researchers at Johns Hopkins have found out how a protein crucial to learning works: by removing a biochemical “clamp” that prevents connections between nerve cells in the brain from growing stronger. The finding moves neuroscientists a step closer to figuring out how learning and memory work, and how problems with them can arise.
An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say. Their findings reveal that obesity-induced changes to the epigenome — reversible chemical “tags” on DNA — are surprisingly similar in mice and humans, and might provide a new route to prevention and treatment of the disease, which affects hundreds of millions worldwide.
Elderly patients admitted to ICUs are 35 percent more likely to die within five years of leaving the hospital if they develop an HAI. Preventing HAIs increases survival odds and cuts costs of care by more than $150,000.
In a study at Washington University School of Medicine in St. Louis, researchers found that a subset of obese people do not have common metabolic abnormalities associated with obesity, such as insulin resistance, abnormal blood lipids (high triglycerides and low HDL cholesterol), high blood pressure and excess liver fat. In addition, obese people who didn’t have these metabolic problems when the study began did not develop them even after they gained more weight.
While people who eat a lot of red meat are known to be at higher risk for certain cancers, other carnivores are not, prompting researchers at the University of California, San Diego School of Medicine to investigate the possible tumor-forming role of a sugar called Neu5Gc, which is naturally found in most mammals but not in humans.
Binge drinking in young, healthy adults significantly disrupts the immune system, a new study has found. While drinkers generally understand how binge drinking alters behavior, there is less awareness of alcohol’s harmful effects in other areas, such as the immune system.
UT Southwestern Medical Center cancer researchers have demonstrated that whole-genome sequencing can be used to identify patients’ risk for hereditary cancer.
Scientists at The Scripps Research Institute have found that resveratrol, the red-wine ingredient once touted as an elixir of youth, powerfully activates an evolutionarily ancient stress response in human cells. The finding should dispel much of and controversy about how resveratrol really works.
By analyzing the DNA and RNA of lung cancers, researchers at the University of Michigan Comprehensive Cancer Center found that patients whose tumors contained a large number of gene fusions had worse outcomes than patients with fewer gene fusions. In addition, the researchers identified several new genetic anomalies that occur in lung cancer, including in patients with a history of smoking.
About one-third of people with type 1 diabetes (T1D) produce insulin, as measured by C-peptide, a byproduct of insulin production, even upward of forty years from initial diagnosis, according to a first-of-its-kind, large-scale study conducted by researchers from T1D Exchange. This sheds new light on the long-accepted belief that these patients lose all ability to produce any insulin; this could have significant policy implications, said researchers from T1D Exchange, whose Clinic Network involves a national consortium of diabetes centers. The findings were published online this week in Diabetes Care.
Migraine headache may double the risk of a nervous system condition that causes facial paralysis, called Bell’s palsy, according to a new study published in the December 17, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Johns Hopkins and University of Alberta researchers have identified a single protein as the root of painful and dangerous allergic reactions to a range of medications and other substances. If a new drug can be found that targets the problematic protein, they say, it could help smooth treatment for patients with conditions ranging from prostate cancer to diabetes to HIV.
In 2014, more teens use e-cigarettes than traditional, tobacco cigarettes or any other tobacco product—the first time a U.S. national study shows that teen use of e-cigarettes surpasses use of tobacco cigarettes.
Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels. Too much Rbm38 reduces p53 levels, increasing the risk of cancer. Too little Rbm38 allows p53 overexpression, causing premature aging. The study was published online in the journal PNAS Dec. 15.
Both positive and negative experiences influence how genetic variants affect the brain and thereby behaviour, according to a new study. “Evidence is accumulating to show that the effects of variants of many genes that are common in the population depend on environmental factors. Further, these genetic variants affect each other,” explained Sheilagh Hodgins of the University of Montreal and its affiliated Institut Universitaire en Santé Mentale de Montréal.
All children should undergo vision health screening between age 36 and 72 months—preferably every year—using evidence-based test methods and with effective referral and follow-up, according to recommendations published in the January issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Sleep-related breathing problems and chronic lack of sleep may each double the risk of a child becoming obese by age 15, according to new research from Albert Einstein College of Medicine of Yeshiva University. The good news is that both sleep problems can be corrected. The study, which followed nearly 2,000 children for 15 years, published online today in The Journal of Pediatrics.
While many different combinations of genetic traits can cause autism, brains affected by autism share a pattern of ramped-up immune responses, an analysis of data from autopsied human brains reveals. The study, a collaborative effort between Johns Hopkins and the University of Alabama at Birmingham, included data from 72 autism and control brains.
Study results of CD19-directed chimeric antigen receptor (CAR) therapy using the Sleeping Beauty non-viral transduction system to modify T cells has demonstrated further promise in patients with advanced hematologic malignancies.
This study is first ever comprehensive analysis to investigate the Affordable Care Act’s ( Essential Health Benefit (EHB) as it relates to children. The study found that the EHB has resulted in a state-by-state patchwork of coverage for children and adolescents that has significant exclusions, particularly for children with developmental disabilities and other special health care needs.
Women over the age of 70 who have certain early-stage breast cancers overwhelmingly receive radiation therapy despite published evidence that the treatment has limited benefit, researchers at Duke Medicine report.
Drugs that boost the function of a specific type of neurotransmitter receptor may provide benefit to patients with the second most common type of dementia, according to research from UAB published today in the Journal of Neuroscience.
A new study is the first to detail the weight loss patterns of exclusively breastfed newborns. The investigators have captured their findings in an online tool that is the first of its kind to help pediatricians determine whether exclusively breastfed newborns have lost too much weight in the first days of life.
The presence of an immune-suppressing protein in non-cancerous immune cells may predict how patients with different types of cancer respond to treatment, a multi-center phase I study using an investigational immune therapy drug has found.
The study, led by a Yale Cancer Center investigator, is described in the Nov. 27 edition of the journal Nature.
Promoting healthy gut microbiota, the bacteria that live in the intestine, can help treat or prevent metabolic syndrome, a combination of risk factors that increases a person’s risk for heart disease, diabetes and stroke, according to researchers at Georgia State University and Cornell University. Their findings are published in the journal Gastroenterology.