Curated News: JAMA

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Released: 2-Apr-2018 12:00 PM EDT
Carta estatutaria para los médicos: compromiso para limitar el agotamiento de los médicos y promover su bienestar
Mayo Clinic

Más del 50 por ciento de los médicos en Estados Unidos dicen sentir agotamiento en su trabajo. Por ello, Mayo Clinic y otros centros médicos principales publicaron hoy una “carta estatutaria para el bienestar de los médicos.”

29-Mar-2018 1:05 PM EDT
Infants Exposed to Antacids, Antibiotics at Increased Risk for Childhood Allergies
Uniformed Services University of the Health Sciences (USU)

Exposing infants to antacids or antibiotics in their first six months of life could increase their risk of developing allergies in childhood.

Released: 29-Mar-2018 11:00 AM EDT
A Medical Charter: Commitments to Limit Physician Burnout, Promote Well-Being
Mayo Clinic

More than half of U.S. physicians say they experience burnout in their work. Today, Mayo Clinic and other leading medical centers have published a “Charter on Physician Well-Being” as an intended model for medical organizations to not only minimize and manage physician burnout, but also promote physician well-being. The charter, which has been endorsed or supported by many major medical organizations, including the American Medical Association and the American Association of Medical Colleges, appears online in JAMA.

27-Mar-2018 4:05 PM EDT
Neurocognitive Risk May Begin Before Treatment for Young Leukemia Patients
St. Jude Children's Research Hospital

Chemotherapy agents have been associated with neurocognitive side effects in young leukemia survivors. Now St. Jude Children’s Research Hospital scientists have evidence the disease and genetics might also play a role.

Released: 29-Mar-2018 7:00 AM EDT
Medical Group Offers Steps to Address Physician Burnout
Mount Sinai Health System

Framework and Principles on Well-Being Aim to Benefit Patients and Strengthen Health Care Systems

Released: 27-Mar-2018 2:05 PM EDT
UCLA-Designed Program Helps Former Inmates with HIV Maintain Health After Release From Jail
University of California, Los Angeles (UCLA), Health Sciences

After years of public health efforts, health care at the Los Angeles County Jail has significantly improved, and the facility now typically provides full access to treatment for inmates who have HIV — including medications that keep their disease in check. When they are released, however, many former inmates stop making regular visits to a doctor and taking the medication they need, which puts their own health at risk and increases the chance they will transmit the virus to others.

22-Mar-2018 3:45 PM EDT
Receptivity to E-cigarette Ads among Young Adults in the U.S. Leads to Cigarette Smoking
UC San Diego Health

Receptivity to advertising for e-cigarettes, cigarettes and cigars were confirmed to be associated with those who would try the respective tobacco product within one year. However, receptivity to e-cigarette advertising also independently increased the odds that 12- to 21-year-olds who have never smoked would try cigarette smoking within the next year by 60 percent. This finding, publishing in the March 26 issue of JAMA Pediatrics, was independent of receptivity to cigarette advertising.

Released: 23-Mar-2018 4:50 PM EDT
Treating Prostate Cancer with Combination of External and Internal Radiation Beneficial
Corewell Health

While there are many treatment options for men with prostate cancer, a recent national study published in JAMA compared the effectiveness of treatments for high-risk prostate cancer.

Released: 19-Mar-2018 2:30 PM EDT
A Surgeon’s Legacy Advances Surgical Care in India
Seattle Children's Hospital

A decade ago, the late Seattle Children’s surgeon, Dr. Richard Grady, began traveling to India to provide urgent surgical care to children with a complex disorder called bladder exstrophy. An article in JAMA Surgery documents Grady's work through an international collaborative aimed at alleviating the global burden of this treatable disease.

13-Mar-2018 12:05 PM EDT
Higher Doses of Radiation Don’t Improve Survival in Prostate Cancer
Washington University in St. Louis

A new study shows that higher doses of radiation do not improve survival for many patients with prostate cancer, compared with the standard radiation treatment. The analysis, which included 104 radiation therapy oncology groups across North America, was led by researchers at Washington University School of Medicine in St. Louis.

12-Mar-2018 5:00 PM EDT
High Prices Are Not the Only Reason Americans Spend So Much More On Healthcare than Europeans
Perelman School of Medicine at the University of Pennsylvania

High drug prices as well as the excessive use of imaging and surgical procedures, and excessive administrative burdens contribute the majority to America’s health care overspending compared to Europe, argues policy expert Ezekiel J. Emanuel, MD, PhD, chair of the department of Medical Ethics and Health Policy at the Perelman School of Medicine at the University of Pennsylvania, in an editorial in this week’s JAMA.

Released: 8-Mar-2018 8:00 AM EST
Older Adults with Small Social Networks Less Likely to Get Cataract Surgery
Michigan Medicine - University of Michigan

A new study from University of Michigan Kellogg Eye Center links familial relationships to the likelihood older adults will get needed cataract surgery — a procedure with broad implications for health.

5-Mar-2018 1:05 PM EST
Children's Hospital of Philadelphia Urologist and Colleagues Address Unmet Global Burden of Surgical Disease in India
Children's Hospital of Philadelphia

Aseem R. Shukla, MD, a pediatric urologist at Children’s Hospital of Philadelphia, along with several of his colleagues from around the world, have created an innovative program to help address urological needs in India. The team is specifically addressing bladder exstrophy, a complex, rare disorder that occurs during fetal development when the bladder does not form completely and drains onto the surface of the abdomen.

6-Mar-2018 3:00 PM EST
Study Draws Links Between Physical Characteristics, Like Age and Body Mass Index, and Brain Health in Psychosis Patients
Mount Sinai Health System

Mount Sinai researchers have shown, for the first time, the complex web of links between physical and behavioral characteristics, like age, body mass index (BMI), and substance use, and specific patterns of brain structure and function in patients with psychosis. The study is important because many of these characteristics can be targeted clinically to improve brain health in these patients.

Released: 7-Mar-2018 10:05 AM EST
Medicare’s Bundled Payment Model for Hip and Knee Surgeries Appears to Work Better For Larger, Higher-Volume Hospitals
Perelman School of Medicine at the University of Pennsylvania

Medicare’s experimental mandatory bundled payment model for knee and hip replacements is more likely to yield cost savings when the surgeries are performed in larger hospitals that do more of these procedures, according to a study from the Perelman School of Medicine at the University of Pennsylvania. Non-profit and major teaching hospital status also appear to be associated with cost savings, the Penn Medicine analysis found.

Released: 7-Mar-2018 8:00 AM EST
MRI Can Help Detect Prostate Cancer, Reduce Unnecessary Biopsies
University of Alabama at Birmingham

In a collaborative, multi-institutional study published by JAMA Oncology, researchers from the University of Alabama at Birmingham, University of Chicago, and National Cancer Institute determined that MRI-based prediction models can help reduce unnecessary biopsies in suspected prostate cancer patients and help improve personalized risk stratification.

Released: 6-Mar-2018 11:05 AM EST
Cognitive Decline Prevalent Among Elderly Patients with Hematologic Cancers, Study Finds
Dana-Farber Cancer Institute

A sizable percentage of elderly patients with blood-related cancers such as leukemia and multiple myeloma are apt to show signs of diminished cognitive functioning

Released: 5-Mar-2018 10:05 AM EST
Many Women Misjudge How They'll Feel After Mastectomy
Yale Cancer Center/Smilow Cancer Hospital

Women who have one or both breasts removed to treat cancer may have unrealistic expectations about how they’ll feel after that surgery and after breast reconstruction, if they choose that option, a U.S. study suggests. Newsmax Article

Released: 1-Mar-2018 4:15 PM EST
Obesity Paradox Debunked
Northwestern University

A new study debunks the “obesity paradox,” a counterintuitive finding that showed people who have been diagnosed with cardiovascular disease live longer if they are overweight or obese compared with people who are normal weight at the time of diagnosis.

Released: 1-Mar-2018 11:05 AM EST
Selfies Drive Self-Image and May Lead Many to Seek Plastic Surgery
Rutgers University-New Brunswick

Rutgers and Stanford researchers develop new mathematical model to explain how smartphones act as “portable funhouse mirrors”

26-Feb-2018 9:00 AM EST
Records Study Suggests Gender Affirming Surgeries On The Rise Along with Insurance Coverage
Johns Hopkins Medicine

In a national medical records analysis, researchers at Johns Hopkins Medicine say there is evidence that the number of gender affirming surgeries performed in hospitals for transgender individuals is on the rise, along with increased access made possible by Medicare, Medicaid or private insurance coverage for the procedures.

Released: 22-Feb-2018 6:05 PM EST
Exercising with Hypertrophic Cardiomyopathy: I Want to Be Fit and Strong
Michigan Medicine - University of Michigan

Signing up for 5Ks and even a 10K is a feat many people with hypertrophic cardiomyopathy may not have dared to attempt a decade or two ago. Fear of tragedy leads many HCM patients to a sedentary lifestyle.

   
Released: 22-Feb-2018 5:05 PM EST
Less Expensive, Post-Acute Care Options for Seniors Underutilized
UT Southwestern Medical Center

Long-term acute care (LTAC) facilities are designed to meet the needs of older adults with severe, complex illnesses who are recovering from hospitalization, but less expensive options sometimes overlooked may also be available, population health researchers at UT Southwestern found.

22-Feb-2018 11:00 AM EST
Study Shows Need for Early Support Among People with Uveal Melanoma
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers found that nearly all people diagnosed with uveal melanoma had a number of unmet psychological and health information needs, particularly during the first three months after their diagnoses. The study is the first prospective, longitudinal approach to examine supportive care needs among patients with this disease, and suggested more acute needs among people with uveal melanoma than people with other cancers.

Released: 15-Feb-2018 8:05 AM EST
University of Pennsylvania Researchers Conduct Comprehensive Evaluation of Patients with Concussion-Like Symptoms Following Reports of Audible Phenomena in Cuba
Perelman School of Medicine at the University of Pennsylvania

A comprehensive evaluation by clinical researchers at the Perelman School of Medicine at the University of Pennsylvania identified a neurological syndrome that left U.S. government personnel serving in Havana, Cuba with persistent memory and thinking dysfunction, as well as vision and balance problems after hearing unusual noises in their homes or hotel rooms. The team published their findings today in JAMA.

8-Feb-2018 12:45 PM EST
Family History Increases Breast Cancer Risk Even in Older Women: Weighing Screening Options
Lombardi Comprehensive Cancer Center at Georgetown University

Family history of breast cancer continues to significantly increase chances of developing invasive breast tumors in aging women — those ages 65 and older, according to research published in JAMA Internal Medicine. The findings could impact mammography screening decisions later in life.

8-Feb-2018 10:05 AM EST
Which Commonly Prescribed Drug is More Effective for Infants with Epilepsy?
Ann and Robert H. Lurie Children's Hospital of Chicago

Comparison of two of the most commonly prescribed drugs for infants with nonsyndromic epilepsy revealed that levetiracetam was more effective than phenobarbital, according a multicenter, observational study published in JAMA Pediatrics. After six months of single-drug treatment, 40 percent of infants who received levetiracetam met criteria for successful outcome – they did not require a second anti-epileptic drug to control their seizures and they became seizure-free within three months of starting treatment. Only 16 percent of infants treated with phenobarbital achieved the same outcome.

Released: 6-Feb-2018 12:05 PM EST
Children Affected by Prenatal Drinking More Numerous than Previously Estimated
UC San Diego Health

Researchers at University of California San Diego School of Medicine found a significant number of children across four regions in the United States were determined to have fetal alcohol spectrum disorders (FASD). The new findings may represent more accurate prevalence estimates of FASD among the general population than prior research.

Released: 2-Feb-2018 9:10 AM EST
Uncovering the Long-Term Health Impact of Playing in the NFL
Perelman School of Medicine at the University of Pennsylvania

In 1987, National Football League players went on strike. As a response, NFL teams scrambled to fill their rosters with “replacement players,” individuals who had some experience with college or professional football, but who weren’t part of NFL rosters that year. The replacement players themselves became a footnote in sports history. It turns out these players may actually play a critical role in football today - by helping us understand how playing in the NFL affects long-term health. In our recent study, published in JAMA, we compared the life expectancies of professional NFL players who debuted between 1982 and 1992 to the life expectancies of replacement players from the 1987 strike.

Released: 1-Feb-2018 4:00 PM EST
Study: Chaplains Crucial for Advance Care Planning in Medical Practice
RUSH

In a study, 80 percent of participants completed an advance directive after meeting with a chaplain as part of a doctor’s appointment

25-Jan-2018 8:05 AM EST
Patients and Doctors Often Disagree in Evaluation of Surgical Scarring
Perelman School of Medicine at the University of Pennsylvania

When it comes to the physical scars surgery leaves behind, a new study shows patients and doctors often don’t assess their severity the same way. Researchers from the Perelman School of Medicine at the University of Pennsylvania found patients and physicians disagreed in their scar evaluations 28 percent of the time, with patients more likely to focus on the depth of the scar while physicians were more likely to emphasize coloration and texture.

30-Jan-2018 11:00 AM EST
MD Anderson Study Evaluates Need for Biopsies During Follow-Up Care in Women with Early Breast Cancer
University of Texas MD Anderson Cancer Center

In an analysis of more than 120,000 women diagnosed with and treated for early-stage breast cancer, researchers from The University of Texas MD Anderson Cancer Center determined the rate of additional breast biopsies needed for these patients during their follow-up care. The findings, reported in JAMA Surgery, are the first comprehensive nationwide population-based study regarding the need for breast biopsies performed during follow up after treatment for invasive breast cancer.

Released: 30-Jan-2018 3:05 PM EST
For Children with Respiratory Infections, Antibiotics with Narrower Targets Are Better
Children's Hospital of Philadelphia

A study of 30,000 children with earaches, strep throat and other common infections found that narrow-spectrum antibiotics had fewer adverse effects than broad-spectrum antibiotics. A more selective approach is better, said researchers.

26-Jan-2018 4:30 PM EST
Body Clock Disruptions Occur Years Before Memory Loss in Alzheimer’s
Washington University in St. Louis

People with Alzheimer’s disease have disturbances in their internal body clocks that affect the sleep/wake cycle and may increase risk of developing the disorder. Researchers at Washington University School of Medicine in St. Louis have found that such circadian rhythm disruptions also occur much earlier in people whose memories are intact but whose brain scans show early, preclinical evidence of Alzheimer’s.

Released: 26-Jan-2018 10:35 AM EST
Research Suggests Colonoscopy Link to Appendicitis
University of North Dakota

Although the incidence of appendicitis in the United States has been in decline for many years, the condition still affects approximately seven percent of Americans annually.

24-Jan-2018 2:25 PM EST
Yale Cancer Researchers Propose New Ways to Select Patients for Clinical Trials
Yale Cancer Center/Smilow Cancer Hospital

Yale Cancer Center investigators have demonstrated in a new study that more sophisticated models to assess patient risk for cancer can result in better clinical trials with more definitive results.

22-Jan-2018 10:05 AM EST
Short-Course Treatment for Combat-Related PTSD Offers Expedited Path to Recovery
Perelman School of Medicine at the University of Pennsylvania

Symptoms of Post-Traumatic Stress Disorder (PTSD) can be debilitating and standard treatment can take months, often leaving those affected unable to work or care for their families. But, a new study demonstrated that many PTSD sufferers can benefit from an expedited course of treatment. In the first study of its kind, Prolonged Exposure (PE) therapy was found to be as effective when administered over two weeks as when it is provided over eight weeks for treating PTSD in active-duty military personnel.

Released: 16-Jan-2018 3:05 PM EST
Bariatric Surgery Prolongs Lifespan in Obese
Northwestern University

Obese, middle-age men and women who had bariatric surgery have half the death rate of those who had traditional medical treatment over a 10-year period, reports a study that answers questions about the long-term risk of the surgery. 

Released: 16-Jan-2018 11:00 AM EST
Pediatric Physician-Scientists Struggle for Funding
Washington University in St. Louis

A new, multicenter study that included Washington University School of Medicine in St. Louis has found that most NIH grants awarded to researchers in pediatrics during the past five years have been limited to physicians in senior positions at a small number of institutions. The findings indicate an overall downward trend in funding for pediatric research, particularly among early-career physician-scientists.

Released: 15-Jan-2018 3:30 PM EST
New Blood Test for Diagnosing Heart Attacks: A ‘Big Deal,’ with Caveats
Michigan Medicine - University of Michigan

A longtime blood test that measures the likelihood of a cardiac event has become more sensitive and more precise. Why doctors and patients should be cautiously optimistic.

Released: 15-Jan-2018 12:30 PM EST
Youth Using Alternative Tobacco Products Are More Likely to Smoke 1 Year Later
UCSF Helen Diller Family Comprehensive Cancer Center

Nonsmoking adolescents who use e-cigarettes, smokeless tobacco or tobacco water pipes are more likely to start smoking conventional cigarettes within a year, according to new research by UC San Francisco.

Released: 4-Jan-2018 7:05 PM EST
Cross-Disciplinary Program Improves Surgical Outcomes for Older Patients
Duke Health

Compared to younger adults, older people have higher rates of complications from surgery. But many problems can be avoided by intervening with assessments and risk-reduction strategies before, during and after procedures.

3-Jan-2018 11:05 AM EST
Small-Cell Lung Cancer Patients Face Barriers to Receiving Standard-of-Care Treatment
University of Texas MD Anderson Cancer Center

Despite decades of clinical research establishing chemotherapy with thoracic radiation as the standard-of-care for the initial management of non-metastatic small-cell lung cancer (SCLC), a large percentage of U.S. patients do not receive these treatments and in turn have lower overall survival, according to research from The University of Texas MD Anderson Cancer Center.

Released: 3-Jan-2018 12:05 PM EST
Facial Exercises Help Middle-Aged Women Appear More Youthful
Northwestern University

A 30-minute daily or alternate-day facial exercise program sustained over 20 weeks improved the facial appearance of middle-aged women, resulting in a younger appearance with fuller upper and lower cheeks, reports a new Northwestern Medicine study.

Released: 2-Jan-2018 12:05 PM EST
Blacks’ High Diabetes Risk Is Driven by Obesity, Not Mystery
Northwestern University

In a surprising finding, blacks and whites have the same risk of developing diabetes when all biological factors for the disease are considered over time, reports a large new Northwestern Medicine study.

28-Dec-2017 12:05 PM EST
Mount Sinai Researchers Find Differences in Very PreTerm Infant Morbidity and Mortality Rates among New York City Hospitals
Mount Sinai Health System

Blacks and Hispanic very preterm infants are more likely to be born at New York City hospitals with higher risk-adjusted neonatal morbidity-mortality rates, and these differences contribute to excess morbidity and mortality among black and Hispanic infants. These differences in hospital of birth explained 39.9% of the black-white disparity and 29.5% of the Hispanic-white disparity in outcomes.

Released: 28-Dec-2017 11:05 AM EST
Carfilzomib Can Lead to Cardiovascular Toxicity in Multiple Myeloma Patients
Perelman School of Medicine at the University of Pennsylvania

The proteasome inhibitor carfilzomib has taken on an increasing role in the treatment of multiple myeloma, but new research from the Abramson Cancer Center of the University of Pennsylvania shows the therapy comes with the risk of cardiovascular problems in a higher than expected percentage of patients.

Released: 28-Dec-2017 9:00 AM EST
Study Shows Increased Risk of Uterine Fibroids in African-American Women with a Common Form of Hair
Johns Hopkins Medicine

In a study of medical records gathered on hundreds of thousands of African-American women, Johns Hopkins researchers say they have evidence that women with a common form of hair loss have an increased chance of developing uterine leiomyomas, or fibroids.

Released: 20-Dec-2017 11:00 AM EST
Better Treatment, Not More Spending, Saves Heart Attack Patients, Study Finds
Michigan Medicine - University of Michigan

A long-term look at heart attack care and spending in America in the 21st Century shows more survival, more spending, and more variation between hospitals on both scores. And while spending on rapid angioplasty appears to be paying off, a lot of the dollars spent in the six months after a heart attack aren’t making a difference in the long-term death rate.

Released: 19-Dec-2017 12:05 PM EST
Electric Scalp Device Prolongs Survival in Deadly Brain Cancer
Northwestern University

A device attached to a patient’s scalp that delivers a continuous dose of low-intensity electric fields improves survival and slows the growth of a deadly brain tumor, according to a new clinical trial led by a Northwestern Medicine scientist and published Dec. 19 in the journal JAMA.



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