Feature Channels: Dermatology

• share
• favorite_border

• share
• favorite_border

• share
• favorite_border

Trending news releases with the most views in a single day. Topics include: neurology, cancer, immunotherapy, Alan Alda present science award, genetics, vision, lung cancer, prostate cancer, environmental health.

• share
• favorite_border

A Phase 3, multicenter clinical trial led by Ludwig Cancer Research investigators Jedd Wolchok and Stephen Hodi shows that the combination of two immunotherapies—ipilimumab and nivolumab—induces more frequent responses and considerably longer progression-free survival in patients with advanced melanoma than the administration of either of them alone. The results of the trial, which confirm those of a smaller study similarly conducted in previously untreated patients by the same Ludwig scientists, were presented today at the 2015 American Society for Clinical Oncology Annual Meeting and published online later today in the New England Journal of Medicine.

• share
• favorite_border

Treating advanced melanoma patients with either a combination of the immunotherapy drugs nivolumab and ipilimumab or nivolumab alone significantly increases progression-free survival over using ipilimumab alone, according to Memorial Sloan Kettering researchers.

• share
• favorite_border

The incidence of melanoma, a deadly form of skin cancer, has increased by more than 250% among children, adolescents and young adults since 1973, according to award-winning research to be presented by Roswell Park Cancer Institute (RPCI) at the American Society of Clinical Oncology (ASCO) 51st Annual Meeting in Chicago.

• share
• favorite_border

Scientists have found that stage IIIb to IV melanoma patients treated with a modified cold sore (herpes) virus had improved survival. The results of the findings were published recently in the Journal of Clinical Oncology.

• share
• favorite_border

Study explains why some melanoma tumors are resistant to BRAF inhibitor treatment

• share
• favorite_border

Trending news releases with the most views in a single day. Topics include: income inequality, climate change, genetics, cancer, precision medicine, medical imaging, schizophrenia, research funding, molecular biology and skin cancer.

• share
• favorite_border

In what they believe to be the first survey of its kind in the United States, researchers at NYU Langone Medical Center have found that as many as 6 percent of adult New Yorkers who get “inked” — in other words, those who get a tattoo — have experienced some form of tattoo-related rash, severe itching or swelling that lasted longer than four months and, in some cases, for many years.

• share
• favorite_border

A three-dimensional imaging technique often used in the automotive and aerospace industries for accurate measurement may be useful to measure the efficacy of injectable wrinkle reducers such as Botox and Dysport, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

• share
• favorite_border

Researchers have uncovered a new molecular mechanism - a function of the NONO protein - whereby cells protect their genome from the detrimental effect of UV radiation and govern DNA replication in cellular mitosis. A recent study investigates what happens when this molecular mechanism malfunctions.

• share
• favorite_border

A national regulatory framework designed to prevent and limit indoor tanning is needed to alleviate the cancer burden and reduce the billions in financial costs from preventable skin cancer, say two Georgetown University public health experts.

• share
• favorite_border

Collagen is the most abundant protein in the human body, and investigators are uncertain how its presence affects the behavior of melanoma cells.

• share
• favorite_border

Trending news releases with the most views in a single day. Topics include: genetics, cancer, nanotech, elderly care, marketing research, energy, children's health, and immunology.

• share
• favorite_border

Research by Howard L. Kaufman, MD, FACS, associate director for clinical science and chief surgical officer at Rutgers Cancer Institute of New Jersey and colleagues shows advanced-stage melanoma patients have significant improvement in durable response rate when treated with a genetically-modified form of a herpes virus, whose native form causes the common cold sore.

• share
• favorite_border

Exposure to ultraviolet radiation is the most preventable risk factor for all types of skin cancer. But according to new research published in the Journal of the American Academy of Dermatology, the majority of Americans are not regularly using sunscreen to protect themselves from the sun’s harmful UV rays.

• share
• favorite_border

Three million cases of skin cancer could be prevented annually by avoiding ultraviolet light. UAB experts share how to pick out the proper UV-protection and use it effectively.

• share
• favorite_border

Although most bug bites and stings are harmless, some can be dangerous. This is especially true if you are allergic to the bug’s venom, or if the bug is carrying a disease. In the United States, it’s common to experience a bite or sting from mosquitoes; fleas; spiders; bees, wasps and hornets; biting flies; mites; ticks; fire ants; and bedbugs.

• share
• favorite_border

Mississippi State University Extension Service agent Shelaine Pennington and MSU Extension health specialist Dr. David Buys discuss Pennington's skin cancer scare and tips for lifestyle changes for Skin Cancer Awareness Month.

• share
• favorite_border

• share
• favorite_border

In findings reported in Cell Death and Differentiation, the researchers demonstrate that the enzyme GMPS drives melanoma growth, and propose a new strategy for targeting that protein.

• share
• favorite_border

In recognition of Melanoma/Skin Cancer Detection and Prevention Month® in May and Melanoma Monday®, observed on May 4 this year, the American Academy of Dermatology (Academy) asks the public to consider “Who’s Got Your Back?” when it comes to applying sunscreen and examining skin for suspicious spots.

• share
• favorite_border

A new treatment for melanoma could be on the horizon, thanks to a finding by a UNC Lineberger Comprehensive Cancer Center-led team. In the study, which was published in the journal Clinical Cancer Research, the authors report that they found high levels of an enzyme in melanoma samples that they believe is a potential drug target.

• share
• favorite_border

Young women may be up on the latest fashions and trends as they prepare for prom season. But what many don’t know is that the tan that looks oh-so-good with their dress may be the first step toward skin cancer.

• share
• favorite_border

A http:team of international scientists has identified hundreds of possible new genes in mice that could transform benign skin growths into deadly melanomas.

• share
• favorite_border

In the first major study to examine the use of a computer-assisted, photo-driven differential diagnosis generator for skin conditions, researchers at the Perelman School of Medicine at the University of Pennsylvania found physicians routinely used the tool, without an increase in calling for inpatient dermatology consultations.

• share
• favorite_border

Skin cancer is the most common form of cancer in the United States, with one in five Americans developing it over the course of their lives.

• share
• favorite_border

Research from Rutgers Cancer Institute of New Jersey and Rutgers School of Public Health shows more than a third of New Jersey high school students who engage in indoor tanning do so frequently and many would find it hard to stop the practice. Investigators also found that frequent indoor tanners were more likely to smoke and to engage in social media activities related to indoor tanning.

• share
• favorite_border

Once again, researchers at Penn’s Abramson Cancer Center have extended the reach of the immune system in the fight against metastatic melanoma, this time by combining the checkpoint inhibitor tremelimumab with an anti-CD40 monoclonal antibody drug.

• share
• favorite_border

If you have a cold sore – small blisters on the lip or around the mouth – you’re not alone. More than half of Americans ages 14 to 49 carry the virus that causes cold sores. The virus stays in the body even after the cold sores clear. If the virus reactivates, or wakes up, you could get cold sores.

• share
• favorite_border

A UNC Lineberger-led study found that people with higher-risk melanoma containing either BRAF or NRAS gene mutations had lower survival rates.

• share
• favorite_border

A new study finds that the incidence of pediatric melanoma in the United States decreased from 2004 to 2010.

• share
• favorite_border

"Tanning beds cause skin cancer. It is time to now more openly announce this causality," says Robert P. Dellavalle, MD, PhD, MSPH, investigator at the CU Cancer Center, in the American Journal of Preventive Medicine.

• share
• favorite_border

The significance of this work is its descriptions of alternative mechanisms by which tumors move and settle in new locations.

• share
• favorite_border

Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients' tumors, according to early data in a first-in-people clinical trial at Washington University School of Medicine in St. Louis. The research is reported April 2 in Science Express.

• share
• favorite_border

Spreading the success of cancer immunotherapy beyond those patients currently enjoying powerful, long-term responses to treatment requires greater understanding of the immune response to tumors, two leaders in the field note in a review in the April 3 Science.

• share
• favorite_border

Researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences produced 3D maps of molecular and microbial variations across the body. These maps provide a baseline for studies of the interplay between the molecules that make up our skin, our microbiomes, our personal hygiene routines and other environmental factors. The study, published March 30 by PNAS, may help further our understanding of the skin’s role in human health and disease.

• share
• favorite_border

An experimental therapy developed by researchers at Albert Einstein College of Medicine of Yeshiva University cut in half the time it takes to heal wounds compared to no treatment at all. Details of the therapy, which was successfully tested in mice, were published online in the Journal of Investigative Dermatology.

• share
• favorite_border

There are nearly 10,000 melanoma deaths in the U.S. each year, and while treatment advances have been made, a majority of melanoma patients will die from their disease. Building on these advances, Rutgers Cancer Institute of New Jersey investigators have demonstrated that removal of a gene involved in the cellular self-cannibalization process of autophagy could provide therapeutic benefit to patients with melanoma.

• share
• favorite_border

Sunbathers could soon tell when to take shelter in the shade thanks to an early warning sunburn indicator, developed by Queen’s University Belfast.

• share
• favorite_border

Medicine obviously can’t do much good if it sits on a pharmacy shelf. Yet more than one-quarter of the acne patients surveyed by Wake Forest Baptist Medical Center researchers didn’t get medications prescribed by their dermatologists.

• share
• favorite_border

Every sport is different, and every athlete has unique needs. No matter their game, though, athletes across the board are prone to five dermatologic issues: blisters, turf burns, athlete’s foot, acne mechanica and exposure to ultraviolet (UV) light. Fortunately, there are ways to prevent these problems and treat them when they occur.

• share
• favorite_border

Within the last five years, targeted therapy and immunotherapy have emerged as viable treatment options for patients with advanced melanoma. Although these therapies have promising implications, early detection still gives patients the best chance of survival.

• share
• favorite_border

Among the new research presented at the American Academy of Dermatology’s 73rd Annual Meeting are two studies examining skin cancer risk in minority populations. One investigation found that gay and bisexual men are more likely to use indoor tanning devices and develop skin cancer than straight men, while another found that Hispanic and Asian women have an increased risk of developing nonmelanoma skin cancer.

• share
• favorite_border

Vitiligo affects the skin, but it’s not just skin deep. This condition can be detrimental to patients’ emotional health, and a recent study indicates that it also may have implications for their physical health. According to research presented at the American Academy of Dermatology’s 73rd Annual Meeting in San Francisco, certain autoimmune diseases, including thyroid disease and alopecia areata, may be more prevalent among vitiligo patients.

• share
• favorite_border

Exfoliation can improve your skin’s appearance and make topical treatments more effective, but every type of exfoliation may not work for every skin type. In fact, some exfoliation treatments may actually make some people’s skin worse. A board-certified dermatologist can help individuals understand their skin and choose the exfoliation option that’s best for them.

• share
• favorite_border

• share
• favorite_border

In the last several years, targeted therapies – drugs that directly impact specific genes and proteins involved in the progression of cancer – have been approved for a wide variety of cancers, including melanoma, the deadliest form of skin cancer. Now, researchers at The Wistar Institute have discovered one way in which melanoma becomes resistant to a particular form of targeted therapy, and understanding this phenomenon may lead to a new melanoma target or prompt new designs of these treatments.

• share
• favorite_border

Today marked the publication of the first ever genome-wide association study of rosacea, a common and incurable skin disorder. Led by Dr. Anne Lynn S. Chang of Stanford University’s School of Medicine, and co-authored by 23andMe, the study is the first to identify genetic factors for this condition.