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Kidney Disease

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Medicine

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Kidney Damage, Radiocontrast, Imaging

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 29-Sep-2016 5:00 PM EDT

Medicine

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Dialysis, Elderly

Study Reveals More Liberal Use of Dialysis in the US Compared with Other Developed Nations

• In a study of VA patients with kidney failure, the overwhelming majority (85.5%) of patients had either received, or were preparing to receive, renal replacement therapy. • Even among members of the oldest age group (≥85 years) with the highest burden of comorbidity, most (51.2%) received or were preparing to receive renal replacement therapy.

Medicine

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Anxiety, Dialysis, Kidney Disease

Anxiety Is an Underrecognized Yet Serious Clinical Problem for Dialysis Patients

• A new review examines how anxiety may affect the health and care of patients with kidney failure who are undergoing hemodialysis.

Medicine

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Cirm, California Institute For Regenerative Medicine, University of California at San Diego, UCSD, Stem Cell, Stem Cell Research, C. Randal Mills, Ph.D., Cystonisis, Blood Stem Cells, Stephanie Cherqui, FDA, Food And Drug Administration, Cysteine

Rare, Life-Threatening Childhood Disease is the Focus of CIRM’s Most Recent Investment

Cystinosis is a rare disease that usually strikes children before they are two years old and can lead to end stage kidney failure before their tenth birthday. Current treatments are limited, which is why the CIRM Board today approved $5.2 million for research that holds the possibility of a safe, effective, one-time life-long treatment.

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Science

Life

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Law and Public Policy

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Presidential Debate: Expert Panel Gives Scientific Analysis of Candidates' Performances

Four expert panelists each day will present their analyses and answer your questions live and face-to-face. This event will be virtual. You can attend with any device -- PC, Mac, iPad, iPhone or Android device (with a webcam) – anywhere with good bandwidth. To participate (ask questions) in the meeting, you must be on video, just as a normal news conference. Register below for guaranteed seating; there is limited seating in the virtual room. Eight experts (four at each event) will present their analyses. The diverse expert team (7 universities and an institute) will analyze both candidates during the debates for their gestures, facial expressions (including smiles--number, type, appropriateness, etc.), posture, language, including sentiment, tone, inflammatory language, repetition, vocabulary, sentence structure, metaphors, framing, themes, suggestions, subtlety, nuance, honesty (deceit/lies—explicit and implicit), transparency, gender issues, and more...

Medicine

Science

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Antibiotic Resistant Bacteria, Kidney Infection

Increase in Antibiotic-Resistant Bacteria Hinders Treatment of Kidney Infections

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Researchers use hospital emergency room data from around the country to document emergence of E. coli strain that fights medication. They recommend development of new antibiotics and treatment guidelines.

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American Society of Nephrology’s Kidney Week 2016: Reinventing Nephrology: From Molecule to Man

The world’s largest gathering of kidney health professionals will join forces in Chicago from November 15–20, 2016, to discuss research discoveries and how to move them from bench to bedside during the American Society of Nephrology’s Kidney Week 2016.

Medicine

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Kidney Transplant, Transplant, organ allocation

New Score Seeks to Expand Pool of Kidneys Available for Transplant

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Researchers from Thomas Jefferson University analyzed data from thousands of transplants and developed a scoring system for donor kidneys that they hope might expand the pool of available organs in two ways. They published their findings in the Annals of Transplantation.

Medicine

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Penn Medicine, Perelman School of Medicine at the University of Pennsylvania, Transplanation, Kindey, Hepatitis C, Clinical Trial

Expanding Access: First Clinical Trial Transplants Hepatitis C-Infected Kidneys at Penn Medicine

Patients who need a kidney transplant may have new hope, through an innovative Penn Medicine clinical trial using kidneys from deceased donors who had the Hepatitis C virus (HCV). The first study participant received a kidney transplant in July 2016, and after being treated with a full regimen of Zepatier – a recently-approved oral medication prescribed to eradicate HCV – her doctors announced today that there is no evidence of the virus in her blood.

Medicine

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Kidney, nephron progenitor (NP) cells, Chronic Kidney Failure, renal regeneration, Cell Renewal, cell repair

Human Kidney Progenitors Isolated, Offering New Clues to Cell Renewal

In a first-of-its-kind look at human kidney development, researchers at The Saban Research Institute of Children’s Hospital Los Angeles have isolated human nephron progenitor (NP) cells. Their results may offer a future way to foster renal regeneration after chronic kidney failure or acute injury.

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Kidney Failure, Diabetes

New Strategy May Help Prevent Kidney Failure in Patients with Diabetes

• A newly developed compound inhibits the deleterious effects of high blood sugar on kidney cells and slows the progression of kidney disease in diabetic mice. • The compound protects the kidneys in both early and advanced phases of diabetes, and it reduces expression of genes associated with kidney inflammation and scarring.

Medicine

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Stem Cells, Chronic Kidney Disease, atheroscleroisis, Cardiovascular Disease, osteoblasts

Scientists Find Culprit Responsible for Calcified Blood Vessels in Kidney Disease

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Scientists have implicated a type of stem cell in the calcification of blood vessels that is common in patients with chronic kidney disease. The research will guide future studies into ways to block minerals from building up inside blood vessels and exacerbating atherosclerosis, the hardening of the arteries.

Medicine

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Ut Southwestern, Kidney Cancer, kidney cancer research, HIF, HIF-2, utsw, Kidney Cancer Program, Simmons Comprehensive Cancer Center, Harold C. Simmons Comprehensive Cancer Center

New HIF-2 Kidney Cancer Therapy More Effective Than Current Treatment, Study Shows

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A new class of drugs called HIF-2 inhibitors is more effective and better tolerated than the standard of care drug sunitinib in treating kidney cancer, researchers with the Kidney Cancer Program at Harold C. Simmons Comprehensive Cancer Center have found.

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living kidney donors

Are Promises Made to Living Donors Being Upheld?

• Most prior living kidney donors in the United States who later need a transplant receive one quickly, but some are not readily given the priority they were promised when they donated.

Medicine

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Dialysis, Nephrology, Older Patients, Geriatric Care, shared decision-making , end-stage renal disease

Older Patients Feel They Have Little Say in Choosing Dialysis, Study Says

Starting dialysis treatment for end-stage renal disease (ESRD) should be a shared decision made by an informed patient based on discussions with a physician and family members. However, many older dialysis patients say they feel voiceless in the decision-making process and are unaware of more conservative management approaches that could help them avoid initiating a treatment that reduces their quality of life, according to a study led by Tufts University researchers.

Medicine

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Cancer, Obesity, Cancer Risk, Cancer Risk Reduction, Stomach Cancer, Liver Cancer, gall bladder cancer, Pancreas Cancer, Ovarian Cancer, Meningioma, Thyroid Cancer, Multiple Myeloma, Excess Weight, Overweight

Excess weight linked to 8 more cancer types

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There’s yet another reason to maintain a healthy weight as we age. An international team of researchers has identified eight additional types of cancer linked to excess weight and obesity: stomach, liver, gall bladder, pancreas, ovary, meningioma (a type of brain tumor), thyroid cancer and the blood cancer multiple myeloma.

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Nanoparticle That Mimics Salmonella Counteracts Chemotherapy Resistance, Protein’s Role in Cell Division, A Novel MRI Method, and MORE in the Cancer News Source

Click here to go directly to the Cancer News Source

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Diabetes, Kidney

New Oral Diabetes Drugs May Also Protect Patients’ Kidney Health

• In a clinical trial of patients with type 2 diabetes, canagliflozin (a sodium-glucose cotransporter 2 inhibitor) slowed kidney function decline to a greater extent than glimepiride (a sulfonylurea), while having similar blood sugar–lowering effects.

Medicine

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Kidney, Chronic Kidney Disease, Diabetes & Endocrinology, UREA

Chronic Kidney Disease May Cause Diabetes

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A new study published in the Journal of Clinical Investigation shows that when kidneys fail, urea that builds up in the blood can cause diabetes.

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HDL, Longevity

Intermediate HDL Cholesterol Levels May Be Best for Longevity

• In a large study of male veterans, both low and high HDL cholesterol levels were associated with higher risks of dying compared with intermediate levels, forming a U-shaped curve. • The beneficial properties of HDL cholesterol were attenuated, but remained significant, in the presence of kidney disease.







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