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Continued Treatment with Nivolumab May Improve Survival in Patients with Advanced Kidney Cancer

Only 12% of kidney cancer patients with advanced disease survive five years after their initial treatment. In a Roswell Park Cancer Institute-led study, scientists report that some patients with advanced kidney cancer who continued to receive a novel immunotherapy drug after their disease progressed saw clinical benefit. The research was published online ahead of print in JAMA Oncology, a journal of the American Medical Association.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 25-May-2016 2:00 PM EDT

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Higher Salt Intake May Increase Risk of CVD among Patients with Chronic Kidney Disease

In a study appearing in the May 24/31 issue of JAMA, Jiang He, M.D., Ph.D., of the Tulane University School of Public Health and Tropical Medicine, New Orleans, and colleagues evaluated more than 3,500 participants with chronic kidney disease (CKD), examining the association between urinary sodium excretion and clinical cardiovascular disease (CVD) events.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 26-May-2016 5:00 PM EDT

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Simple Public Health Intervention May Prevent Chronic Kidney Disease

• Kidney function remained unchanged among hypertensive adults in communities assigned to a public health intervention for general practitioners and community health workers, whereas kidney function significantly declined among those who received usual care. • Individuals in the communities with the intervention were half as likely as other individuals to experience a >20% decline in kidney function within 5 years after the intervention was stopped.

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Screening Strategy Identifies Adults at Risk for Developing Kidney Disease

• In the See Kidney Disease (SeeKD) Targeted Screening program undertaken by the Kidney Foundation of Canada, 89% of patients who were screened reported at least 1 risk factor for chronic kidney disease (CKD), and of those, 19% had unrecognized CKD.

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Big Data, Better Care for Chronic Kidney Disease Patients

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A team of physicians from Christiana Care Health System and computer scientists from the University of Delaware is using merged electronic health records to improve care and clinical outcomes for patients with chronic kidney disease, which affects some 26 million American adults.

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Technique May Improve Understanding, Detection of Kidney Disease

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UT Dallas scientists are developing an innovative research technique that could help urologists better understand the early stages of kidney disease.

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Top Stories 5-17-2016

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Top Stories 5-16-2016

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Top Stories 5-13-2016

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Kidney Disease May Increase Hospitalized Patients’ Risk of Complications

• In a study of hospitalized patients, those with chronic kidney disease were 19% more likely to experience hospital acquired complications than patients with normal kidney function. • There was a graded relation between the risk of complications and kidney disease severity.

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Smartphone-Based System May Improve Health of Patients with Chronic Diseases

• A smartphone-based system helped patients with chronic kidney disease monitor their blood pressure, symptoms, and medications. • The system also alerted patients’ physicians about medication errors and other potential harms.

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Exercise May Reduce the Risk of Cervical Cancer, Breast Cancer Screening Accuracy, Genome Analysis Leads to Clues About Rare Cancer, and more in the Cancer News Source

Exercise May Reduce the Risk of Cervical Cancer, Breast Cancer Screening Accuracy, Genome Analysis Leads to Clues About Rare Cancer, and more in the Cancer News Source

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Top Stories 5-11-2016

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Common Antacid Linked to Accelerated Vascular Aging

Chronic use of some drugs for heartburn and gastroesophageal reflux (GERD) speeds up the aging of blood vessels, according to a published paper in Circulation Research (early online), an American Heart Association journal. This accelerated aging in humans could lead to increased cardiovascular disease, vascular dementia and renal failure.

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Top Stories 5-10-2016

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Climate Change May Contribute to Rising Rates of Chronic Kidney Disease

• Chronic kidney disease that is not associated with traditional risk factors appears to be increasing in rural hot communities as worldwide temperature progressively rises. • The condition has likely increased due to global warming and an increase in extreme heat waves, and it is having a disproportionate impact on vulnerable populations.

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Study Finds Improvements in Warfarin Use for Atrial Fibrillation Treatment Necessary to Protect Kidney Function and Heart Health

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Atrial fibrillation patients taking warfarin, a popular anticoagulation drug, are at higher risk of developing kidney failure if anticoagulation levels are not properly managed, according to a new study from researchers at the Intermountain Medical Center Heart Institute.

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Common Supplement Boosts Kidney Cancer Therapy

Researchers at UC Davis have shown that docosahexaenoic acid (DHA), a fatty acid commonly found in fish and fish oil supplements, reduces renal cell carcinoma invasiveness, growth rate, and blood vessel growth when combined with the anti-cancer therapy regorafenib. The study was published in the May issue of the journal Molecular Cancer Therapeutics.