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Predictor of Tissue Injury in Kidney Transplant Recipients Found

Researchers at UC San Francisco and Rush University Medical Center, Chicago, may have found a predictor for a disorder affecting kidney transplant recipients that can accelerate organ failure, a discovery that eventually could allow for customized therapies and improved patient selection for transplant.

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Mysterious Balkan Disease’s Likeliest Risk Factor Also in Chinese Medicines

Scientists speculate that the highest risk factor for a kidney disease common to five Balkan nations is a plant commonly used in various Chinese herbal medicines.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 2-Oct-2014 5:00 PM EDT

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 2-Oct-2014 5:00 PM EDT

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Cooling of Dialysis Fluids Protects Against Brain Damage

• Dialysis drives progressive white matter brain injury due to blood pressure instability; however, patients who dialyzed at 0.5◦C below body temperature were completely protected against such white matter changes.

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Many Kidney Failure Patients Have Concerns About Pursuing Kidney Transplantation

• Among new dialysis patients, the most frequently cited concerns were that patients felt they were doing fine on dialysis and felt uncomfortable asking someone to donate a kidney. • Older age was linked with having high health-related or psychosocial concerns, as was being a woman, being less educated, and having more comorbid illnesses. • Patients having such concerns had less than half the chance of getting listed for a transplant than those without them.

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Keryx Biopharmaceuticals Receives FDA Approval of Ferric Citrate

Keryx Biopharmaceuticals, Inc. (Nasdaq:KERX) (the "Company") today announced that the U.S. Food and Drug Administration (FDA) approved Ferric Citrate (formerly known as Zerenex) for the control of serum phosphorus levels in patients with chronic kidney disease (CKD) on dialysis.

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Hospitalizations for Heart Failure Increase Kidney Disease Patients’ Risk of Kidney Failure, Premature Death

Highlight • Among patients with chronic kidney disease, the risks of developing kidney failure or dying prematurely increased markedly in a step-wise fashion after each successive hospitalization for heart failure.

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Calcium Buildup in Coronary Arteries Predicts Heart Disease Risk in Patients with Chronic Kidney Disease

• Calcium build-up in the coronary artery walls was more useful for correctly predicting kidney disease patients’ risk of heart disease than other measures of atherosclerosis such as thickness of the carotid artery walls and narrowing of the arteries in the legs.

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Measuring Calcium Buildup Is a Better Way to Predict Heart Disease in Those with Chronic Kidney Disease

Calcium buildup in the coronary arteries of chronic kidney disease patients may be a strong indicator of heart disease risk, according to a new study released in the Journal of the American Society of Nephrology (JASN). Researchers at the Johns Hopkins Bloomberg School of Public Health assert that coronary calcium outperforms two other commonly used measures of subclinical atherosclerosis in predicting the risk of heart disease among individuals with kidney disease.

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