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Article ID: 697182

Crystal Structure Reveals How Curcumin Impairs Cancer

University of California San Diego Health

Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 (DYRK2) at the atomic level. This previously unreported biochemical interaction of curcumin leads to inhibition of DYRK2 that impairs cell proliferation and reduces cancer burden.

Released:
9-Jul-2018 3:35 PM EDT
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Article ID: 696485

Light-Based, 15-Second Scan Aims to Replace Painful Mammograms

National Institute of Biomedical Imaging and Bioengineering

Up to 50% of women skip potentially life-saving mammograms often because they can cause extreme discomfort. Now researchers have developed a painless, light-based, non-radioactive, 15-second procedure that could revolutionize breast cancer screening and save lives.

Released:
21-Jun-2018 2:05 PM EDT
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Article ID: 694701

Improving Survival in Pancreatic Cancer with Platinum-Based Chemotherapy

Johns Hopkins Medicine

A small study of adults with the most common form of pancreatic cancer adds to evidence that patients with BRCA1 or BRCA2 gene mutations long linked to a high risk of breast cancer have poorer overall survival rates than those without the mutations.

Released:
17-May-2018 8:00 AM EDT
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  • Embargo expired:
    10-May-2018 4:00 PM EDT

Article ID: 693844

Study Reveals That Many Oncologists Recommend Medical Marijuana Clinically Despite Not Feeling Sufficiently Knowledgeable to Do So

Dana-Farber Cancer Institute

While a wide majority of oncologists do not feel informed enough about medical marijuana’s utility to make clinical recommendations, most do in fact conduct discussions on medical marijuana in the clinic and nearly half recommend it to their patients, say researchers who surveyed a population-based sample of medical oncologists.

Released:
1-May-2018 5:00 PM EDT
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Article ID: 692455

New Drug Combo Improves Survival of Women with Rare Uterine Cancer

Johns Hopkins Medicine

Adding the monoclonal antibody drug trastuzumab—already used to treat certain breast cancers—to the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to Johns Hopkins Medicine researchers conducting a small phase II trial of the regimen, testing its safety and value.

Released:
10-Apr-2018 10:00 AM EDT
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  • Embargo expired:
    14-Mar-2018 4:30 PM EDT

Article ID: 691041

Targeting a Signaling Pathway with a Diabetes Drug may be a Potential Strategy in Treating, Preventing Pancreatic Cancer Progression

Rutgers Cancer Institute of New Jersey

Research by Rutgers Cancer Institute of New Jersey investigators explores the use of a diabetes drug and its impact on pancreatic cancer and finds that targeting a certain signaling pathway with this agent may be a novel strategy for the prevention and treatment of metastatic pancreatic cancer.

Released:
13-Mar-2018 2:40 PM EDT
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Article ID: 690825

Acute Myeloid Leukemia Patients Have Reduced Early Mortality at NCI-Designated Cancer Centers

UC Davis Comprehensive Cancer Center

Researchers at UC Davis have shown that patients with acute myeloid leukemia (AML) who received their care at a National Cancer Institute (NCI) cancer center in California had a dramatically reduced risk of early mortality. Using data from the California Cancer Registry and the Patient Discharge Dataset, the team determined that the risk was reduced by 53 percent. These findings were reported in February in the journal Cancer.

Released:
8-Mar-2018 3:30 PM EST
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  • Embargo expired:
    22-Feb-2018 9:00 AM EST

Article ID: 689651

Phase I Clinical Trial Shows Some Promise for Investigational Drug for Melanoma

University of North Carolina Health Care System

In JCI Insight, researchers reported the results of a phase I, multi-institution clinical trial for an investigational treatment for melanoma and other cancers with mutations in the BRAF or RAS genes.

Released:
19-Feb-2018 9:00 AM EST
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  • Embargo expired:
    21-Feb-2018 2:00 PM EST

Article ID: 689759

New Therapeutic Gel Shows Promise Against Cancerous Tumors

University of North Carolina Health Care System

UNC and NC State scientists created an injectable gel-like scaffold that can hold combination chemo-immunotherapeutic drugs and deliver them locally to tumors in a sequential manner. The results in animal models suggest this approach could one day ramp up therapeutic benefits for cancer patients.

Released:
19-Feb-2018 11:30 AM EST
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Article ID: 689321

Blood Test Plus Ultrasound Boosts Liver Cancer Detection by 40 Percent

UT Southwestern Medical Center

Combining ultrasound imaging with a blood test for high alpha fetoprotein (AFP) levels improves detection of early-stage liver cancer by as much as 40 percent, researchers at UT Southwestern’s Simmons Cancer Center found.

Released:
9-Feb-2018 3:50 PM EST
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