Protection against symptomatic COVID-19 begins to decrease after one month from initial vaccination, while immunity against severe COVID-19 remains high for about six months, according to a recent study by Penn State College of Medicine scientists.
A National Institutes of Health-funded study has found that people with food allergies are less likely to become infected with SARS-CoV-2, the virus that causes COVID-19, than people without them.
The nervous system is known to communicate with the immune system and regulate inflammation in the body.
"Just understanding the immune responses to these vaccines will help us integrate what is successful into vaccine designs going forward.”
Adults infected with COVID-19 develop circulating antibodies that last for nearly 500 days, according to a new study led by researchers at UTHealth School of Public Health.
Tiny antibodies in sharks have dexterity and flexibility that human antibodies do not. They can bind tightly to the spike proteins of coronaviruses and neutralize the virus. This could help researchers develop new vaccines and therapies for COVID-19.
One powerful way cancer cells defend against tumor-killing immune cells is to load up their cell surface with a protein known as PD-L1. Now a team of UCLA Jonsson Comprehensive Cancer Center researchers led by Roger S. Lo, MD, PhD, has identified a method to degrade tumor cell-surface PD-L1, thereby making tumors susceptible to immune attack.
Professor George Fu Gao, HKIAS Senior Fellow and the Director-General of the Chinese Center for Disease Control and Prevention in China, was recently elected a Foreign Member of the Royal Society for his contributions in the field of infection and immunity, particularly relating to emerging viral infections, have helped to improve our understanding of major threats to human health.
Research drawing on the national Overcoming COVID-19 study, led by Boston Children’s Hospital, and the hospital’s own Taking On COVID-19 Together Group provides evidence that children who previously had COVID-19 (or the inflammatory condition MIS-C) are not protected against the newer Omicron variant.
Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body’s white blood cells to go on the attack against a foreign presence.
A case report published in the New England Journal of Medicine provides evidence that enterovirus D68 directly infects spinal cord neurons and that a corresponding robust immune response is present – a direct causation to the polio-like paralyzing illness, acute flaccid myelitis (AFM). Matthew Vogt, MD, PhD, assistant professor of pediatrics and microbiology & immunology at the UNC School of Medicine is the lead author of the study.
Scientists at the University of Michigan fabricated a nanoparticle to deliver an inhibitor to brain tumor in mouse models, where the drug successfully turned on the immune system to eliminate the cancer. The process also triggered immune memory so that a reintroduced tumor was eliminated—a sign that this potential new approach could not only treat brain tumors but prevent or delay recurrences.
A recent study jointly conducted by the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and the Faculty of Medicine, The Chinese University of Hong Kong (CU Medicine) shows that vaccinated individuals can develop more robust and broadly reactive antibody responses against SARS-CoV-2 variants than unvaccinated individuals after an Omicron infection.
In a new study, researchers at the University of Chicago Medicine Comprehensive Cancer Center and the University of Amsterdam have brought insight into one crucial step in the anti-cancer immune response process: T cell priming.
Throughout the pandemic the University of Huddersfield’s Department of Pharmacy has been raising awareness on what vaccines are, how they are formulated, and why they're an important part of the healthcare strategy as well as the progress on further developments in COVID vaccines, so that people can make an educated decision on becoming vaccinated or if choosing for their children.
Immune response and the lymphatic system are central to cardiac repair after a heart attack, according to a study from Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg Cardiovascular Research Institute. These insights into the basic mechanisms of cardiac repair are the first step towards developing novel therapeutic approaches to preserve heart function. Findings were published in the Journal of Clinical Investigation.
An international team led by a University of Toronto researcher has found that an antibody detectable in blood predicts severe Crohn’s disease and is detectable up to seven years prior to disease diagnosis.
Study found that some drugs were on the market for over five years with no confirmed clinical benefit.
Primary immunodeficiency disorders (PID) can result in chronic and sometimes life-threatening infections.
Young children who grow up with a dog or in a large family may have some protection later in life from a common inflammatory bowel disease known as Crohn’s disease, according to a study to be presented at Digestive Disease Week® (DDW) 2022.
Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai.
Thanks to over a century of modern neuroscience, we have made significant strides in our understanding of the brain.
By uniting research from 8 cohorts across the U.S., a group of researchers has accelerated collection of data integral in answering questions about immune responses needed for long lasting protection from SARS-CoV-2.
Genetic factors played a greater role in a person's overall wellbeing as the pandemic wore on.
A COVID-19 booster shot will provide strong and broad antibody protection against the range of omicron sublineage variants of the SARS-CoV-2 virus in circulation, two new studies using serum from human blood samples suggest.
New research using a mouse model for multiple sclerosis has uncovered a potential new area to explore for possible treatments for autoimmune disorders.
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McMaster University researchers have discovered that Type I interferon (IFN) plays a key role in helping the immune system effectively target viruses, while stopping white blood cells from ‘going rogue’ and attacking the body’s own organs.
A new paper in Family Practice, published by Oxford University Press, indicates that receiving hormone replacement therapy within six months of a recorded diagnosis of COVID-19 was associated with a reduction in mortality from the disease.
New research from scientists at UC Davis Health provides clues for how friendly bacteria in the gut — probiotics — may help eradicate bacterial pathogens like Salmonella by being able to compete with them for needed resources.
COVID-19, MIS-C and KD all share a similar underlying mechanism involving the over-activation of particular inflammatory pathways, UC San Diego study shows. Findings support novel drug targets for MIS-C.
Evidence continues to gather that ‘long Covid’, that is, continued negative health impacts months after apparent recovery from severe Covid-19, is an important risk for some patients.
Distinct genetic variants significantly influence an individual's immune response to the SARS-CoV-2 virus and may influence the COVID-19 disease severity.
Researchers have shown for the first time in mice that heart problems seen in some of the sickest flu patients are caused by direct influenza infection of cardiac cells.
A study led by UC Davis Cancer Center identified a binding protein in cancer cell’s nucleus, known as CHD4, as a critical agent keeping Kaposi's sarcoma-associated herpesvirus (KSHV) dormant and undetected by the body’s immune system. CHD4 is linked to cancer cell growth in many types of cancers.
Ten years ago, Tom and Kari Whitehead came to Children’s Hospital of Philadelphia (CHOP) looking for a miracle. Their 6-year-old daughter, Emily, had relapsed in her battle with acute lymphoblastic leukemia (ALL), after many months of unsuccessful chemotherapy and a disease that had progressed so rapidly that she was ineligible for a bone marrow transplant to treat it. Her family came to CHOP in the hopes that Dr. Stephan Grupp, a pioneer in the field of cellular immunotherapy, could provide the miracle they were looking for.
The acute psychosocial stress states stimulate the secretion of an antibody type protein which is decisive in the first immune defence against infection, but only after puberty.
Researchers at MD Anderson and Ochsner Health have uncovered that in immunotherapy, a particular cytokine is expressed at higher levels in colitis tissue than in cancer tissue.
To treat and prevent these diseases, researchers need to understand why a lack of oxygen would affect the immune system.
Pfizer has NOT declared their COVID vaccines unsafe for pregnancy and breastfeeding women, despite misleading claims on social media, nor have they said that the real efficacy rate for their vaccine (COMIRNATY) is 12 percent.
Through single-cell RNA sequencing, a research group has successfully illuminated the characteristics of Myeloid immune cells in coronary plaque, which causes acute coronary syndrome (this term includes conditions such as unstable angina and acute myocardial infarction (heart attack)). Based on this data, they hope to develop a treatment method that can stabilize coronary plaque.
Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study led by UT Southwestern researchers suggests. The findings, published in Cancer Cell, could offer a new strategy to fight pancreatic cancer, a deadly disease for which no truly effective treatments exist.
A new study finds that the normal-appearing skin of lupus patients contains the same inflammatory signals that are detected when the skin develops a rash, sometimes at even higher levels. Researchers say immune cells undergo an inflammatory transformation that primes the skin without rashes for disease flares.
Researchers at Washington University School of Medicine in St. Louis have received a $6 million grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health (NIH) to harness new understandings of the immune system to develop innovative therapies for heart failure and the prevention of organ rejection following heart transplantation.
Researchers have discovered the blood clotting and immune protein pathways that are activated in severe cases of COVID-19 in children, paving the way for earlier diagnosis and more targeted treatments.
If you’re wondering why after two vaccination doses and a booster shot, you still got sick from the omicron strain of the virus that causes COVID-19, one possible answer may have been found in a recent study by researchers at Johns Hopkins Medicine and the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH).
Ted Ross, Ph.D., has been appointed Global Director of Vaccine Development at Cleveland Clinic. In this newly created role, he will lead the development of novel vaccine platforms for a variety of infectious diseases, including influenza, HIV and COVID-19. A highly renowned scientist with expertise in virology, vaccines, immunology and microbiology, Dr. Ross’ research focuses on the design of new vaccines and the implementation of new vaccine trials.
Scholars from HSE University and the RAS Institute of Bioorganic Chemistry have demonstrated the efficiency of T-cell immune response against the Omicron variant of SARS-CoV-2.
In a research letter to the journal JAMA Oncology, clinical researchers at Sylvester Comprehensive Cancer Center in the University of Miami Miller School of Medicine showed that immunotherapy can be an option for at least one subgroup of pancreatic cancer patients. The study found that patients with inherited BRCA and other similar mutations can achieve complete responses — in some cases going from near death to durable recoveries.
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