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Medicine

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GIST, Cancer, Gastroenterology, Genetics, Genetic Screening, Intestinal Cancer

GIST Tumors Linked to NF1 Mutations, Genetic Testing Needed

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Researchers at UC San Diego Moores Cancer Center, with colleagues from Memorial Sloan Kettering Cancer Center and Fox Chase Cancer Center, have determined that a specific region of the small bowel, called the duodenal-jejunal flexure or DJF, shows a high frequency of gastrointestinal stromal tumors (GISTs) with mutations of the NF1 gene.

Medicine

Science

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Nanoengineering, nanotechnnology, micromotors, Micromachines, Drug Delivery, UC San Diego Jacobs School of Engineering, Stomach Infection, Helicobacter Pylori, In Vivo

Drug-Delivering Micromotors Treat Their First Bacterial Infection in the Stomach

Nanoengineers at the University of California San Diego have demonstrated for the first time using micromotors to treat a bacterial infection in the stomach. These tiny vehicles, each about half the width of a human hair, swim rapidly throughout the stomach while neutralizing gastric acid and then release their cargo of antibiotics at the desired pH.

Science

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Phytoremediation, NASA Ames Research Center, NASA Ames, University of Washington, Trichloroethylene, TCE, poplar tree

Probiotics Help Poplar Trees Clean Up Toxins in Superfund Sites

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Biologists conducted the first large-scale experiment on a Superfund site using poplar trees fortified with a probiotic — or natural microbe — to clean up groundwater contaminated with trichloroethylene, or TCE.

Science

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Genomics, Microbiology, microbial classification, single-cell genomics, Metagenomics, Metadata, single amplified genomes, metagenome-assembled genomes, genome standards, Data Quality, genome quality, Data Management, Databases, Microbes, Environment

Defining Standards for Genomes From Uncultivated Microorganisms

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In Nature Biotechnology, an international team led by DOE Joint Genome Institute researchers has developed standards for the minimum metadata to be supplied with single amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) submitted to public databases.

Medicine

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Massry Prize, Microbiome, Cell Biology, Molecular Biology, Biotechnology, Microbiology, Awards, Meira and Shaul G. Massry Foundation

2017 Massry Prize Honors Microbiome Research Pioneers

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Microbiome researchers Rob Knight, PhD, University of California San Diego, Jeffrey Gordon, MD, Washington University School of Medicine in St. Louis, and Norman Pace, PhD, University of Colorado Boulder, will share this year’s Massry Prize, splitting the $200,000 honorarium. These researchers lead a field that works to produce a detailed understanding of microbiomes andand methods for manipulating them for the benefit of human and environmental health.

Medicine

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Autoimmune Disease, Gastroenterolgy, human gut microbe, Biomedical Research, intestinal mirobiome, multiple sclerosis

Human Gut Microbe May Lead to Treatment for Multiple Sclerosis

Mayo Clinic researchers, along with colleagues at the University of Iowa, report that a human gut microbe discovered at Mayo Clinic may help treat autoimmune diseases, such as multiple sclerosis. The findings appear in Cell Reports.

Science

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 20-Aug-2017 5:00 AM EDT

Medicine

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Science, Tissue Repair, Tissue Regeneration, Therapeutics, Drug Development, Prostaglandins, Healing, Internal Medicine, Gastroenterolgy, Liver, Colon, mice model, Inflammatory Bowel Disease

Case Western Reserve University Researchers Develop Therapeutic to Enhance Tissue Repair and Regeneration

Rodeo Therapeutics, a new drug development company created by two highly regarded Case Western Reserve University School of Medicine researchers, has raised $5.9 million to develop small-molecule drugs that promote the body’s repair of diseased or damaged tissues.

Medicine

Science

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intestinal inflammation , Inflammatory Bowel Disease, Therapeutic, National Institute Of Diabetes And Digestive And Kidney Diseases, National Institutes Of Health (NIH), Didier Merlin, Tim Denning, Nanoparticles, Institute for Biomedical Sciences

Researchers Get $1.4 Million to Study Novel Therapeutic Approaches to Treat Intestinal Inflammation

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Researchers in Georgia State University’s Institute for Biomedical Sciences have received a four-year, $1.4 million federal grant to study novel therapeutic approaches for the treatment of intestinal inflammation.

Medicine

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Influenza, gut microbiome, Flavonoids

Natural Compound Coupled with Specific Gut Microbes May Prevent Severe Flu

Researchers at Washington University School of Medicine in St. Louis have found that a particular gut microbe can prevent severe flu infections in mice, likely by breaking down naturally occurring compounds — called flavonoids — commonly found in foods such as black tea, red wine and blueberries.







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