A review of nearly 582,000 heart attack cases over 19 years showed female patients had a significantly higher survival rate when a woman treated them in the ER, according to research from faculty at the University of Minnesota-Twin Cities, Washington University in St. Louis and Harvard.
Researchers have found an important contributor to heart pathology caused by the cancer drug doxorubicin — disruption of metabolism that controls immune responses in the spleen and heart. This allows chronic, non-resolving inflammation that leads to advanced heart failure.
Rutgers University–New Brunswick engineers have created a smart wristband with a wireless connection to smartphones that will enable a new wave of personal health and environmental monitoring devices. Their technology, which could be added to watches and other wearable devices that monitor heart rates and physical activity, is detailed in a study published online in Microsystems & Nanoengineering.
Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut. The research, published in the September issue of Nature Medicine, was led by Stanley Hazen, M.D., Ph.D.
For the first time, researchers at University of California San Diego School of Medicine and Imperial College London, with international collaborators, have determined that Kawasaki Disease (KD) can be accurately diagnosed on the basis of the pattern of host gene expression in whole blood. The finding could lead to a diagnostic blood test to distinguish KD from other infectious and inflammatory conditions.
Johns Hopkins researchers say a heart imaging study of scores of pregnant women with the most severe and dangerous form of a blood pressure disorder has added to evidence that the condition — known as preeclampsia — mainly damages the heart’s ability to relax between contractions, making the organ overworked and poor at pumping blood.
Heart transplant patient who had to be hooked up to machines to walk his daughter down the aisle will compete in Olympic-style sporting events at this year's Transplant Games of America.
Experts from the world’s major heart surgery organizations—including The Society of Thoracic Surgeons (STS), the American Association for Thoracic Surgery (AATS), the Asian Society for Cardiovascular and Thoracic Surgery (ASCVTS), and the European Association for Cardio-Thoracic Surgery (EACTS)—are calling for urgent action to develop and implement effective strategies for treating rheumatic heart disease (RHD).
Transgender individuals may be at higher risk for heart disease, according to a review article published by Michael S. Irwig, MD, associate professor of medicine at the George Washington University School of Medicine and Health Sciences, in Reviews in Endocrine and Metabolic Disorders.
A new study from the UCLA School of Nursing published in the American Journal of Cardiology found that just a half-hour of hookah smoking resulted in the development of cardiovascular risk factors similar to what has been seen with traditional cigarette smoking.
The Women’s Heart Fund raised over $140,000 in support of the Center for Survivorship and Wellness Care at Hackensack Meridian Health Jersey Shore University Medical Center’s HOPE Tower last month. More than 220 people came out to the Bay Head Yacht Club in Bay Head, New Jersey on June 1 in support of the center’s comprehensive, and compassionate, holistic cancer care services.
The Cardiothoracic Surgery Division at Stony Brook University Heart Institute has earned the highest quality rating of three stars from The Society of Thoracic Surgeons (STS)
After a successful, two-year pilot project that helped patients reverse their metabolic syndrome with lifestyle changes, the William G. McGowan Charitable Fund is expanding the Eat, Love, Move (ELM) program to five cities through a six-year clinical trial, totaling $9 million in grants to Rush University Medical Center.
A UCLA-led study found that many people with heart failure do not receive the medications recommended for them under guidelines set by the American College of Cardiology, American Heart Association and Heart Failure Society of America. The research also found that doctors frequently prescribe medications at doses lower than those recommended by the guidelines, especially for older people, those with kidney disease, those with worsening symptoms or those who were recently hospitalized for heart failure.
A U.S.-based survey of women with polycystic ovary syndrome (PCOS), a common condition characterized by reproductive and metabolic problems, points to distrust and lack of social support from healthcare providers as major contributing factors in their negative medical care experiences, according to a new study published in the Endocrine Society’s Journal of the Endocrine Society.
A new drug-delivery technology which uses red blood cells to shuttle nano-scale drug carriers, called RBC-hitchhiking, has been found in animal models to dramatically increase the concentration of drugs ferried precisely to selected organs.
The Second Annual University of Utah Translational Hypertension Symposium assembles national experts in hypertension treatment and research. This year's meeting will focus on implementation strategies for the 2017 American College of Cardiology/American Heart Association guidelines, the future of hypertension research, and a mentored workshop for early-stage investigators.
The word sabbatical could conjure up all sorts of envy in non-academics who may hear the term and think only of “paid time off.” However, this “time away” is anything but “time off.”
Medical teams at the Vanderbilt Transplant Center (VTC) are leading the way in utilization of hepatitis C-exposed donors for heart transplantation.
A University of Virginia Health System program that provides follow-up care for heart failure patients after they leave the hospital significantly improves survival and other outcomes while saving money, a new study finds.
A team of researchers led by cardiologists at UT Southwestern Medical Center has developed a new online tool to more accurately predict who among those ages 40-65 is at the highest risk of suffering a heart attack or stroke in the next 10 years.
Pairing an online patient dashboard with “nudges” to doctors tripled statin prescribing rates in a clinical trial led by Penn Medicine researchers. The study used two nudges, active choice framing to prompt physicians to make a decision on prescriptions, and peer comparison feedback which provided physicians with information on their performance relative to other physicians.
Mice fed a fattening diet develop new liver circadian rhythms that impact the way fat is accumulated and simultaneously burned. The team found that as liver fat production increases, surprisingly, so does the body’s ability to burn fat. These opposing physiological processes reach their peak activity each day around 5 p.m., illustrating an unexpected connection between overeating, circadian rhythms, and fat accumulation in the liver.
Patients who undergo coronary artery bypass grafting (CABG)—the most common heart surgery performed—may live longer and experience fewer complications when under the care of a highly focused surgical team that uses simplified and standardized approaches.
In a study published online July 25 in the journal Nature, University of California San Diego School of Medicine researchers identified a signaling pathway that activates the NLRP3 inflammasome implicated in several severe chronic inflammatory disorders.
First Optimizer® Smart investigational device for heart disease implanted in the Philadelphia Area
In the U.S., it's estimated the number of people aged 65 and older will double over the next 30 years. With the first baby boomers now turning 73, the demand for cardiac care is expected to skyrocket, not just in the U.S. but elsewhere as well. Even though they have more cardiovascular problems, fewer women and people over 65 are recruited for randomized clinical trials than men and younger people. To find out, a team of researchers took a close look at the 25 most influential clinical trials for each year in the 20-year period from 1996 to 2015. They compared the age and sex of participants to data published in the U.S. National Health and Nutrition Examination Survey 2015-2016 on the prevalence of cardiovascular disease in America.
A drug currently in clinical trials for treating symptoms of Parkinson’s disease may someday have value for treating heart failure, according to results of early animal studies by Johns Hopkins Medicine researchers.
Gestational diabetes may increase the risk of blood vessel dysfunction and heart disease in offspring by altering a smooth muscle protein responsible for blood vessel network formation. Understanding of the protein’s function in fetal cells may improve early detection of disease in children. The study is published ahead of print in the American Journal of Physiology—Cell Physiology.
Shape Memory Medical recently announced FDA clearance for U.S. marketing of their IMPEDE Embolization Plug, a technology funded by NIBIB and created to block irregular blood vessels.
Postmenopausal factors may have an impact on the heart-protective qualities of high-density lipoproteins (HDL) – also known as ‘good cholesterol.’ The findings bring into question the current use of total HDL cholesterol to predict heart disease risk.
The number of patients undergoing mitral valve operations are at an all-time high, and new research suggests that many patients don’t undergo surgical intervention until it’s too late to completely reverse damage caused by mitral valve disease.
NYU Langone study serves as an important reminder of how stressful pregnancy can be on the female body and heart, causing a lot of physiological changes, and potentially unmasking risk factors that can lead to heart attack.
With the help of a $1.54 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health, a research team from Wayne State University will establish a targeted approach to sustain cardiac function during an energetic crisis and heart failure.
In the heart, aging can disrupt the protein network within muscle cells that move blood around the body. However, a new discovery in how heart muscles maintain their shape in fruit flies sheds light on the crucial relationship between cardiac function, metabolism, and longevity. Researchers have discovered that maintaining high levels of the protein vinculin confers health benefits to fruit flies. Their work, published in APL Bioengineering, shows that fruit flies bred to produce 50 percent more vinculin enjoyed better cardiovascular health and lived a third of their average life span longer.
The Cardiovascular Research Foundation (CRF) is pleased to announce that its premier translational research facility, the CRF Skirball Center for Innovation (SCI), is partnering with Siemens Healthineers to advance their imaging capabilities for structural heart disease research. SCI is dedicated to guiding early ideas and innovations in cardiology through comprehensive preclinical research programs to introduce practical clinical therapies to patients. As part of this collaboration, SCI will now offer a Siemens Healthineers SOMATOM Definition Flash CT scanner, which will help expand SCI’s research capabilities and maximize efficiencies for its sponsors.
A team of University of Iowa researchers built a web-based app called MapTrek. When synced with a Fitbit, MapTrek allows users to go on virtual walking tours of locations such as the Grand Canyon or Appalachian trail while competing against other users. A study showed MapTrek and Fitbit users averaged 2,200 more steps per day than a control group that used only Fitbits.
The operating rooms where Dr. Michael E. DeBakey and others performed the firsts in the heart surgery will close as the Houston Methodist DeBakey Heart & Vascular Center moves to a new high-tech building.
A new study led by University of Alabama at Birmingham Researchers shows that multivitamins and mineral supplements do not prevent heart attacks, strokes or cardiovascular death.
Air pollution; thorax toxicology; PBPK modeling of antibiotics in dairy cattle; PCBs & steatohepatitis; uranium mine particles & cardiopulmonary toxicity; green plasticizers & reproductive health; and antiandrogenic mixtures & male reproduction featured in latest issue of Toxicological Sciences
New evidence shows the power of a method aimed at changing the longstanding problem of encouraging patients with chronic diseases to take their medicine faithfully: insurance plans that charge patients less for the medicines that could help them most. Some plans even make some of the medicines free to the patients with certain conditions.
Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, the first demonstration of a clinically relevant reduction of gene expression in a large animal model using genome editing. This finding could lead to a possible new approach for treating heart disease patients who do not tolerate PCSK9 inhibitors—drugs that are commonly used to combat high cholesterol.
Symptoms of depression and anxiety are present in about one-third of patients with heart failure – and these patients are at higher risk of progressive heart disease and other adverse outcomes, according to a review and update in the July/August issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.
A new study published in Circulation, a peer-reviewed journal of the American Heart Association and led by a cardiologist at the Peter Munk Cardiac Centre at Toronto General Hospital has found evidence that only one of the 21 genes normally associated with Brugada Syndrome is a definitive cause of the condition.
Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego have found that the cost for the 10 “highest spend” medications in Medicare Part D — the U.S. federal government’s primary prescription drug benefit for older citizens — rose almost one-third between 2011 and 2015, even as the number of persons using these drugs dropped by the same amount.
A Smidt Heart Institute patient is the first in the country to receive a new device to fix a leaky heart valve. The patient, Sheldon Kardener, MD, received the device July 1 during a 30-minute minimally invasive procedure in Cedars-Sinai’s Cardiac Catheterization Lab as a treatment for mitral valve regurgitation. The procedure was performed by Saibal Kar, MD, widely regarded as one of the foremost experts in mitral valve repair. Kardener was discharged and returned home Monday morning.
Using data from large clinical trials, UT Southwestern researchers developed a way to predict which patients will benefit most from aggressive high blood pressure treatment.
A new study finds a newer blood thinner may be a safer choice for reducing stroke risk in those who have both end-stage kidney disease and atrial fibrillation.
A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.
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