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Drug Resistance

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Early Detection of Leukemia Patients' Resistance to Therapy

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Australian researchers have made a world-first breakthrough in the early detection of patients' resistance to a common treatment for chronic myeloid leukemia.

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Scientists Use Already-Approved Drugs to Force Cancer Cell Death, How to Decide if Watchful Waiting Is the Right Choice, Some Adolescent Cancer Survivors May Require More Comprehensive Mental Health Screening, and MORE in the Cancer News Source

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Researchers Identify Regulatory System in Ulcer-Causing Bacteria That Controls Formation of Bacterial Communities

Researchers have discovered a regulatory system in the ulcer- and stomach cancer-causing bacteria, Helicobacter pylori, that can control the formation of biofilm – a “fortress-like” cluster of cells that can become resistant to antibiotics and cause major medical problems.

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Genetic Target Could Help Fight Deadly Drug-Resistant Infections

Fungal infections pose a major threat to hospital patients and have proven difficult to combat, but scientists have unlocked evidence that could lead to more effective treatment.

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Simple Method Quickly Tests Hard-to-Treat Bacteria’s Susceptibility to Different Antibiotics

The recent emergence of bacterial infections that are resistant to many existing antibiotics is driving an urgent need for tools to quickly identify the small number of therapies that are still effective for individual patients. Currently, multi-drug resistant bacteria often must be sent to specialized laboratories for analysis, leading to several days of delay before results can guide therapy. Now investigators at Beth Israel Deaconess Medical Center (BIDMC) have developed a simple and versatile method using inkjet printing technology to test such bacteria for susceptibility to antibiotics in a clinical setting. The method, already available online, is described in the September issue of the Journal of Clinical Microbiology.

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Boston Subway System Covered in Microbes, but They're Not Harmful

Boston’s subway system, known as the T, might be just as bacteria-laden as you’d expect but organisms found there are largely from normal human skin and incapable of causing disease, according to a study published June 28 in mSystems, an open access journal of the American Society for Microbiology.

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Dopamine Receptor Blockade Seen as Cause for Antipsychotic Drug Side-Effects

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University of California, Irvine scientists led by Emiliana Borrelli and colleagues have discovered the key cellular mechanism that underlies the antipsychotic-induced parkinsonism – which includes involuntary movements, tremors and other severe physical conditions. These studies present evidence that will stimulate a targeted approach for the design of novel antipsychotics without side-effects.

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CDC Awards Rush and Cook County $9.45 Million to Combat 'Superbugs'

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A collaboration between Rush University Medical Center and Cook County Health and Hospitals System, considered a national model for developing strategies to combat drug resistant bacteria, was awarded nearly $10 million by the CDC

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Zika Mosquitoes Differ From West Nile Mosquitoes; First Zika Vaccine to Be Tested in Human Clinical Trial; Potential Drug Target Identified for Zika, and MORE in the Zika Virus News Source

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Plant Kingdom Provides 2 New Candidates for the War on Antibiotic Resistance

New research has discovered peptides from two crop species that have antimicrobial effects on bacteria implicated in food spoilage and food poisoning They are similar in structure to a human peptide used to guard against beer-spoiling bacteria

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UNM Health Sciences Center Wins Award to Expand Drug Development

The University of New Mexico Health Sciences Center has joined a national network of scientists on the leading edge of drug discovery and development in the fight against cancer, centered at the Frederick National Laboratory for Cancer Research.

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Switched-on Salmonella: Fluid Forces Guide Disease Traits of Multidrug-Resistant Bacteria

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Once inside the human body, infectious microbes like Salmonella face a fluid situation. They live in a watery world, surrounded by liquid continually flowing over and abrading their cell surfaces--a property known as fluid shear.

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Narrow Wavelength of UV Light Safely Kills Drug-Resistant Bacteria, Finds Columbia’s Center for Radiological Research

Scientists from Columbia University’s Center for Radiological Research have shown that a narrow wavelength of ultraviolet light safely killed drug-resistant MRSA bacteria in mice, suggesting its potential to reduce surgical site infections.

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Scientists Receive $3.5 Million From NIH to Study Drug Resistance in a Global Parasitic Disease

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Dr. Tim Anderson at Texas Biomedical Research Institute and Dr. Phil LoVerde at the University of Texas Health Science Center at San Antonio have been awarded a $3.5 million grant over the next five years by the National Institutes of Health to understand the genetic changes in the schistosome parasite that lead to drug resistance.

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New Clues Found to Immune System’s Misfiring in Autoimmune Diseases; Brain Power; Converting Cirrhosis-Causing Cells to Healthy Liver Cells in Mice, and More in the Cell Biology News Source

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Drop in Childhood Obesity Cannot Be Explained by Health Behaviors, The Latest in Heart Defect Prediction Tech, Eating After 8pm Not Linked to Childhood Obesity, and more Children's Health News

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Harvard Chemists Develop Simple New Platform for Development of Macrolide Antibiotics

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Harvard researchers have created a new, greatly simplified, platform for antibiotic discovery that may go a long way to solving the crisis of antibiotic resistance.

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Top Stories 5-17-2016

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Top Stories 5-16-2016

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Top Stories 5-13-2016

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