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A reporter's PressPass is required to access this story until the embargo expires on 2-Feb-2015 3:00 PM EST

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SLU Scientist Aims to Improve Antibiotics to Treat Staph Infections

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Saint Louis University's Mee-Ngan F. Yap, Ph.D., discovered new information about how antibiotics like azithromycin stop staph infections, and why staph sometimes becomes resistant to drugs.

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How Staph Infections Elude the Immune System

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By tricking the immune system into generating antibodies specific for only one bacterial protein, Staphylococcus aureus dodges the production of antibodies that might otherwise protect against infection. Vaccine approaches must be designed to side-step this bacterial subterfuge.

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A Real-Time Tracking System Developed to Monitor Dangerous Bacteria Inside the Body

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Combining a PET scanner with a new chemical tracer that selectively tags specific types of bacteria, Johns Hopkins researchers working with mice report they have devised a way to detect and monitor in real time infections with a class of dangerous Gram-negative bacteria. These increasingly drug-resistant bacteria are responsible for a range of diseases, including fatal pneumonias and various bloodstream or solid-organ infections acquired in and outside the hospital.

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Study Finds Old Drug Still Reliable, Safe in Treating Staphylococcus aureus

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A University of Nebraska Medical Center research team has determined that a longtime antibiotic, vancomycin, is still effective in treating Staphylococcus aureus bloodstream infections and that physicians should continue to use the drug even though several newer antibiotics are now available in the marketplace.

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MRSA Biofilms in Joint Fluid Make Infections Tough to Tackle

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Scientists from Thomas Jefferson University and the National Institutes of Health come one step closer to understanding the difficulty of treating joint infection. Biofilm formation plays a role.

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Expert: Texas Tech Professor Leading Antibiotic-Resistant Bacteria Research

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Sandia Researchers Find Clues to Superbug Evolution

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A team of Sandia National Laboratories microbiologists for the first time recently sequenced the entire genome of a Klebsiella pneumoniae strain, encoding New Delhi Metallo-beta-lactamase (NDM-1). They presented their findings in a paper published in PLOS One, “Resistance Determinants and Mobile Genetic Elements of an NDM-1 Encoding Klebsiella pneumoniae Strain.”

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Old Drug May Be Key to New Antibiotics

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An anticonvulsant drug called lamotrigine is the first chemical inhibitor of the assembly of ribosomes in bacteria.

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Scripps Research Institute Chemists Modify Antibiotic to Vanquish Resistant Bacteria

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Scientists at The Scripps Research Institute (TSRI) have devised a new antibiotic based on vancomycin that is powerfully effective against vancomycin-resistant strains of MRSA and other disease-causing bacteria.