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Old Drug May Be Key to New Antibiotics

An anticonvulsant drug called lamotrigine is the first chemical inhibitor of the assembly of ribosomes in bacteria.

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Scripps Research Institute Chemists Modify Antibiotic to Vanquish Resistant Bacteria

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Scientists at The Scripps Research Institute (TSRI) have devised a new antibiotic based on vancomycin that is powerfully effective against vancomycin-resistant strains of MRSA and other disease-causing bacteria.

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Biochemists Find New Treatment Options for Staph Infections, Inflammatory Diseases

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Kansas State University biochemists have discovered a family of proteins that could lead to better treatments for Staphylococcus aureus, a pathogenic bacterium that can cause more than 60,000 potentially life-threatening infections each year.

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Bacterial Meningitis Incidence Drops in the United States

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Advances in the prevention and treatment of an often fatal condition called bacterial meningitis appear to be paying dividends in the United States, report infectious disease experts at The University of Texas Health Science Center at Houston (UTHealth) in the journal The Lancet Infectious Diseases.

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Pregnant Women and Fetuses Exposed to Antibacterial Compounds Face Potential Health Risks 


As the Food and Drug Administration mulls over whether to rein in the use of common antibacterial compounds that are causing growing concern among environmental health experts, scientists are reporting today that many pregnant women and their fetuses are being exposed to these substances. They will present their work at the 248th National Meeting & Exposition of the American Chemical Society, the world’s largest scientific society.

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Slaying Bacteria with Their Own Weapons

A novel antibiotic delivery system would exploit small molecules called siderophores that bacteria secrete to scavenge for iron in their environments. Each bacterium has its own system of siderophores, which it pumps across its cell membrane before releasing the iron the siderophores hold. If an antibiotic were linked to one of these scavenger molecules, it would be converted into a tiny Trojan horse that would smuggle antibiotics inside a bacterium’s cell membrane.

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Kryptonite for Superbugs: Scientists Unearth What May Be a Secret Weapon in the Urgent Battle Against Antibiotic-Resistance

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A fungus living in the soils of Nova Scotia could offer new hope in the pressing battle against drug-resistant germs that kill tens of thousands of people every year, including one considered a serious global threat.

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Antibiotic Developed 50 Years Ago May Be the Key to Fighting ‘Superbugs’

The aim of the project is to evaluate novel dosing regimens for polymyxin combinations to maximize antibacterial activity and to minimize the emergence of resistance and toxicity, says Tsuji, principal investigator on the grant.

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Why Transatlantic Trade Must Play a Role in Addressing Antibiotic Resistance

Leading public health researchers and trade experts will convene in Washington to address the spread of antibiotic resistance, the role of food animal production and the consequences of using the Transatlantic Trade and Investment Partnership to weaken existing standards to facilitate trade.

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E-cigarettes May Boost Resistance of Drug-Resistant Pathogens

Despite being touted by their manufacturers as a healthy alternative to cigarettes, e-cigarettes appear in a laboratory study to increase the virulence of drug- resistant and potentially life-threatening bacteria, while decreasing the ability of human cells to kill these bacteria

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