Feature Channels: Cardiovascular Health

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Doctors use invasive procedures to decide whether an ablation procedure to remove heart tissue is likely to have a positive outcome. CT scans or ultrasounds are useful in determining the structure of a patient’s heart, but invasive electrical procedures are used to identify and localize the source of the atrial fibrillation. Researchers from the University of California, Santa Barbara have developed new algorithms to localize the source of an atrial fibrillation. They report their findings in APL Bioengineering.

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For the first time, the American Neurological Association’s 143rd Annual Meeting will feature a media roundtable on Monday, October 22, 2018 from 11:50-1:00 p.m. at which presenters of the six principal symposia will present highlights, discuss the relevance of the work, and answer questions. To RSVP for the media roundtable and request dial-in information if you are not able to attend in person, please contact Rachel Brown at [email protected].

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A patient-centered, team-based model of care that navigates patients through the entire surgical experience is successful in improving quality of care and outcomes in elderly patients being treated for fractures and children undergoing heart surgery, suggest two new studies being presented at the ANESTHESIOLOGY® 2018 annual meeting.

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Researchers are investigating whether infants born into poverty have stronger inflammatory responses, predisposing them to chronic disease during their lives.

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The inaugural Magee Prize was awarded to Pitt's Dr. Yaacov Barak to research in how placental defects may lead to congenital heart defects.

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Despite a common belief that weekend and holiday discharge after major heart surgery may impact hospital readmissions, research published online today in The Annals of Thoracic Surgery showed that day of discharge does not affect readmissions.

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Vaping has surpassed all other forms of tobacco use in middle- and high-schoolers. New research led by Mark Olfert, an associate professor in the West Virginia University School of Medicine, suggests if teenagers continue to vape into adulthood, the cardiovascular effects may, by some measures, be as dire as if they’d smoked cigarettes.

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An international team of researchers has shown in mice that a healthy gut microbiome is important for recovery after a heart attack.

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For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth. The research offers proof-of-concept for prenatal use of a sophisticated, low-toxicity tool that efficiently edits DNA building blocks in disease-causing genes.

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A team of nurses and physicians has received a four-year, $3 million grant from the National Heart, Lung, and Blood Institute to extend traditional HIV treatment protocols to improve the cardiovascular health of people living with HIV.

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A side effect of opioid use is an infection of the heart valves called drug-associated infective endocarditis. Researchers at the University of North Carolina at Chapel Hill have found a tenfold increase in the number of hospitalizations and surgeries for endocarditis in the past decade.

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A new nationwide study has found that a tiny clip placed in the heart to fix a leaky mitral valve drastically decreases the risk of both dying and returning to the hospital for heart failure patients.

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A new DNA tool created by Michigan State University can accurately predict people’s height, and more importantly, could potentially assess their risk for serious illnesses, such as heart disease and cancer.

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In a new study, researchers have found that the gut microbiome appears to play a key role in how well the body accepts a transplanted heart. The scientists found a causal relationship between the presence of certain microbes and transplant outcome.

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Analyzing data from more than 400,000 people, researchers at Washington University School of Medicine in St. Louis have found that consuming one to two drinks four or more times per week — an amount deemed healthy by current guidelines — increases the risk of premature death by 20 percent.

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A new Food-PRICE study from researchers at Tufts and Harvard estimates that up to one million cardiovascular and diabetes events and $42 billion could be saved in healthcare costs using incentives and/or disincentives to improve food choices among participants in SNAP.

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Extreme dieting causes short-term body changes that may have long-term health consequences, according to a new study. The findings will be presented today at the American Physiological Society’s (APS) Cardiovascular, Renal and Metabolic Diseases: Sex-Specific Implications for Physiology conference in Knoxville, Tenn.

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The differences in the way males and females respond to a high-fat, high-sugar diet may include impairment of female fertility, new research suggests. The findings will be presented today at the American Physiological Society’s (APS) Cardiovascular, Renal and Metabolic Diseases: Sex-Specific Implications for Physiology conference in Knoxville, Tenn.

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Patients with “broken heart” syndrome still face considerable risk of hospital readmission and in-hospital death.

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Foundation Awards Presented for Ethics and Creativity in Medical Research, and Societal Impact in Business & Biotechnology

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Heart experts have long believed that weekday mornings – and especially Mondays – were the danger zones for unexpected deaths from sudden cardiac arrests. But a new Cedars-Sinai study shows those peak times have disappeared and now, sudden cardiac arrests are more likely to happen on any day at any time.

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Delaying pregnancy may increase the risk of cardiovascular disease in both women and their children, with boys at higher risk of disease, according to a new study. Researchers from the University of Alberta in Canada will present their findings today at the American Physiological Society’s (APS) Cardiovascular, Renal and Metabolic Diseases: Sex-Specific Implications for Physiology conference in Knoxville, Tenn.

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Mount Sinai Health System urges the general public, especially students, to learn lifesaving CPR and how to use an automated external defibrillator to reduce sudden cardiac death rates.

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A relatively new accelerated diagnostic protocol is effective in identifying emergency department patients with acute chest pain who can be safely sent home without being hospitalized or undergoing comprehensive cardiac testing, according to researchers at Wake Forest Baptist Medical Center.

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A commonly used biomarker of kidney disease may also indicate lung problems, particularly COPD, or chronic obstructive pulmonary disease, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

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Vanderbilt University Medical Center’s Cardiac Surgery Team performed Tennessee’s first total artificial heart implantation Wednesday, Sept. 26, on a 56-year-old man with congestive heart failure.

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The Endocrine Society today issued a Clinical Practice Guideline that offers best practices for healthcare providers on how to promptly diagnose, treat, and manage patients with congenital adrenal hyperplasia (CAH), an inherited endocrine disorder, throughout their entire lives.

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Cardiologists at Henry Ford Hospital performed the first implantation in the United States of a device approved for use in Europe for hard-to-treat angina. The Neovasc Reducer was successfully implanted in a middle-aged, Detroit-area man on June 19. Within six to eight weeks, tissue then grows over the mesh, narrowing the passageway. The patient described greatly diminished symptoms at a recent follow-up.

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Northern Arizona University professor Amirhossein Arzani authored a paper about which computational modeling of blood is more accurate when applied to monitoring the movement of blood through the human body, which affects how doctors treat patients with heart disease.

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A person’s biological sex can be a defining factor in how well—or how poorly—they respond to disease, therapy and recovery. Experts at the forefront of sex-specific research will convene next week at the sixth APS conference on sex differences in cardiovascular and renal physiology. The Cardiovascular, Renal and Metabolic Diseases: Sex-Specific Implications for Physiology conference will be held September 30–October 3 in Knoxville, Tenn.

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A University of Adelaide-led team of researchers has found a link between sudden cardiac death (when the heart suddenly stops beating) and a common heart condition known as mitral valve prolapse that affects around 12 in every 1000 people worldwide.

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Renowned experts collaborate to expand the comprehensive cardiac services offered in Monmouth and Ocean counties.

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NYU College of Dentistry and its World Health Organization (WHO) Collaborating Center, together with NYU College of Global Public Health, will host an event on Friday, September 28, on accelerating global progress in addressing oral health.

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The first randomized trial of its kind was unable to establish non-inferiority of oral anticoagulation (OAC) alone to combined OAC and a single antiplatelet agent (APT) in patients with atrial fibrillation (AF) and stable coronary artery disease beyond one year after stent implantation.

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Results from the Lipid-Rich Plaque (LRP) study demonstrate the correlation between the presence of non-flow-limiting, non-intervened upon, lipid-rich plaques detected by NIRS-IVUS imaging and the development of a major adverse cardiac event (MACE) from a de novo culprit lesion at both the patient level (vulnerable patients) and segment level (vulnerable plaques) within 24 months post intravascular imaging.

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The first study designed to determine the benefits of intravascular ultrasound (IVUS) guidance over angiography guidance during drug-eluting stent (DES) implantation in all-comer patients found that IVUS improved clinical outcomes by lowering the rate of target vessel failure at one year.

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The Cardiovascular Research Foundation (CRF) is pleased to announce that Aria CV has won the TCT 2018 Shark Tank Competition which took place during the Transcatheter Cardiovascular Therapeutics (TCT) 2018, the world’s premier educational meeting specializing in interventional cardiovascular medicine. The winner was also presented with the Jon DeHaan Foundation Award for Interventional Innovation today in the Main Arena of the San Diego Convention Center.

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In the largest multi-institutional study to date, led by researchers from Penn Medicine, the team found that among patients who underwent a transcatheter aortic valve replacement, a high number experienced severe and moderate cases of prosthesis-patient mismatch. The team also found that the risk of death and of heart failure readmissions were higher.

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Data presented today from the randomized COAPT trial, which have the potential to significantly change current clinical practice, found that patients with heart failure and secondary mitral regurgitation (MR) who remained symptomatic despite maximally tolerated medical therapy demonstrated reduced rates of hospitalizations and death, as well as improved quality-of-life and functional capacity after being treated with the transcatheter MitraClip device.

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The first randomized study to compare general versus local anesthesia during transcatheter aortic valve replacement (TAVR) in patients with intermediate to high surgical risk found local anesthesia to be both safe and effective. In addition, the study found that a current generation balloon-expandable valve had similar outcomes to a current generation self-expanding one.

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A multicenter clinical trial has found that a minimally invasive procedure called transcatheter mitral valve repair significantly reduced hospitalizations and mortality for heart failure patients with moderate-to-severe or severe functional mitral regurgitation.

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This first randomized clinical study of a polymer-coated zotarolimus-eluting stent (Resolute Onyx) that utilizes a novel thin-strutted metallic platform allowing for better x-ray visibility was shown to be non-inferior to an ultrathin-strutted bioresorbable polymer-coated sirolimus-eluting stent (Orsiro) that uses a cobalt-chromium strut platform.

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The first large, randomized trial comparing a novel polymer-free amphilimus-eluting stent to the latest-generation permanent polymer drug-eluting stent found that the polymer-free stent was clinically safe and effective.

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Study shows there is a genetic predisposition to early-onset AFib in blacks and Latinos that is greater than what is observed in whites.

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In a study of 1,978 older adults publishing Sept. 21 in the journal Scientific Reports, researchers at Duke Health and the Duke Clinical Research Institute found people with irregular sleep patterns weighed more, had higher blood sugar, higher blood pressure, and a higher projected risk of having a heart attack or stroke within 10 years than those who slept and woke at the same times every day.

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A new study published in the Journal of the American Heart Association shows disparities between the care given to black and white patients seeking treatment for a type of heart attack called NSTEMI (Non-ST-elevation myocardial infarction).

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Attention has focused on how NSAIDs may cause dysfunction of the immune system. Researchers now have found that sub-acute pretreatment with the NSAID carprofen before experimental heart attack in mice impaired resolution of acute inflammation following cardiac injury.

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Diabetics are at least twice as likely as nondiabetics to die of heart disease. They’re also at a greater risk of heart attack. With a two-year, $53,000 fellowship from the American Heart Association, Quincy Hathaway, a doctoral candidate in the West Virginia University School of Medicine, is examining how a certain protein, called PNPase, influences mitochondria’s performance in heart cells.