Antismoking advertising effectively promotes attempts to quit smoking among vulnerable population groups, including minorities and people with lower education and income, according to a new study by researcher at RTI International.
The groundbreaking scientific studies featured at the 2014 AACC Annual Meeting & Clinical Lab Expo will include research on a blood test for Alzheimer’s that uses biochip technology, a new test to diagnose colon cancer early, a more accurate method for determining multiple myeloma prognosis, a less stressful test for sleep apnea, and the development of a bank of biospecimens from pregnant women that could prove crucial for women’s health research.
In lab experiments using tissue samples cultured from cystic fibrosis patients, scientists at the UNC School of Medicine and the UNC Marsico Lung Institute have shown that a new CF drug counteracts the intended beneficial molecular effect of another CF drug.
Pulmonary inflammation can cause shallow breathing and the lungs to become brittle in patients who experience multiple blood transfusions, sepsis, lung surgery and acute lung trauma. This complication can leave patients on ventilators, which can further traumatize the lungs, and often results in a mortality rate of 30 to 40 percent. To date, no medication has been successful at preventing or mitigating the damage caused by lung inflammation. Now, a multidisciplinary research team led by David Eckmann, MD, PhD, Horatio C. Wood Professor of Anesthesiology and Critical Care at the Perelman School of Medicine at the University of Pennsylvania and professor of Bioengineering in Penn’s School of Engineering and Applied Science, has found that when delivered by a microscopic transporter called a nanocarrier, steroids can access the hard-to-reach lung endothelial cells that need it most and are successful at preventing inflammation in mice.
In a new study of the causes underlying respiratory symptoms in military personnel returning from duty in Iraq and Afghanistan, a large percentage of veterans had non-specific symptoms that did not lead to a specific clinical diagnosis.
The so called fatty liver disease that long time drinkers develop may extend to the lung in a newly discovered side effect of drinking in rats that researchers are calling fatty lung disease.
A Johns Hopkins-led research team has found that motivational interviewing, along with standard education and awareness programs, significantly reduced secondhand smoke exposure among children living in those households.
Researchers from The Saban Research Institute of Children’s Hospital Los Angeles are employing state-of-the-art animation technology, in combination with advanced optical imaging and high-resolution x-ray imaging techniques, to map the developing human lung.
National and state air pollution controls that went into effect in the early 1990s coincide with decreasing death rates from emphysema, asthma and pneumonia among people in North Carolina, according to a study led by Duke University researchers.
Researchers have identified hundreds of long non-coding RNAs expressed in developing and adult lungs. Many of these non-protein-coding RNAs in the lung regulate gene expression by opening and closing the DNA scaffolding on neighboring genes.
A first-of-its-kind yoga exercise program has been developed by Henry Ford Hospital for patients living with pulmonary hypertension, a chronic lung disease that afflicts women at least two times more than men. Called Yoga for PH, the 40-minute program includes three yoga exercise levels and a nutrition and lifestyle discussion. It is available for free download on iTunes and Googleplay.
The American Medical Group Foundation (AMGF) today announced the release of the Best Practices in Managing Patients with Chronic Obstructive Pulmonary Disease Compendium.
Duke Clinical Research Institute (DCRI) has launched a patient registry to help researchers and clinicians identify, manage and study people who have a progressive lung disease called idiopathic pulmonary fibrosis. The registry, a joint effort by DCRI and Boehringer Ingelheim Pharmaceuticals, Inc., is the first multi-center registry in the United States focused specifically on idiopathic pulmonary fibrosis.
UNC School of Medicine researchers have provided the first quantitative evidence that mucins – the protein framework of mucus – are significantly increased in cystic fibrosis patients and play a major role in failing lung function.
A study presented at the American Society of Clinical Oncology (ASCO) Annual Meeting 2014 reports the results of a first-in-human, phase 1 dose escalation trial of crizotinib (XALKORI) in 14 patients with advanced, MET-amplified non-small cell lung cancer (NCT00585195).
Results of a University of Colorado Cancer Center study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) show that a test of organic compounds in exhaled breath can not only distinguish patients with lung cancer from patients with chronic obstructive pulmonary disease (COPD), but can also define the stage of any cancer present.
Late Pulmonary Function Abnormalities are Common Among Iraq/Afghanistan Veterans
ATS 2014, SAN DIEGO – Sure, everyone knows a healthy diet provides lots of health benefits for patients with respiratory diseases, but now a new study has shown a direct link between eating fish, fruit and dairy products and improved lung function among patients with chronic obstructive pulmonary disease (COPD).
Reminders prompting asthma patients to take their control inhalers if they miss a dose significantly improve medication adherence, according to a primary-care based study conducted by a research team in Australia. In this six-month investigation, patients receiving reminders took on average 73% of their prescribed doses compared to only 46% in patients who did not have reminders.
Maternal intake of dietary methyl donors during the first trimester of pregnancy modulates the risk of developing childhood asthma at age 7, according to a new study presented at the 2014 American Thoracic Society International Conference.
Both high and low frequency hearing impairment have been linked with sleep apnea in a new study of nearly 14,000 individuals.
ATS 2014, SAN DIEGO ─ The link between stroke and obstructive sleep apnea (OSA) has been established by several clinical studies in recent years, with the most significant risks attributed to male patients. Now, a new study by researchers from Boston says the link between OSA and stroke may be just as strong among women.
In adults with persistent asthma, elevated blood eosinophil levels may be able to predict which individuals are at increased risk for exacerbations, according to a new study presented at the 2014 American Thoracic Society International Conference.
Cigarette smoking and male sex are significant risk factors for developing ocular sarcoidosis, according to a new study presented at the 2014 American Thoracic Society International Conference.
ATS 2014, SAN DIEGO ─ Pulmonary hypertension patients from lower socioeconomic groups present for initial evaluation at a more advanced disease state than those from higher income groups, according to a new study presented at the 2014 American Thoracic Society International Conference.
In patients with congestive heart failure, obesity and a larger waist size have paradoxically been associated with a better prognosis in the prior investigations. This effect, known as the obesity paradox phenomenon, is now being demonstrated in patients with severe pulmonary hypertension.
Home testing of obstructive sleep apnea (OSA) followed by initiation of home treatment with an auto-titrating continuous positive airway pressure (CPAP) device reduced costs compared with in-laboratory testing and titration without negatively impacting clinical outcomes, researchers have shown in a new study presented at the American Thoracic Society International Conference.
A pedometer-based walking program supported by Internet-based instruction and support can improve health-related quality of life (HRQOL) in patients with chronic obstructive pulmonary disease (COPD), according to a new study presented at the 2014 American Thoracic Society International Conference.
A large study of intensive care patients in California found that public reporting of patient outcomes did not reduce mortality, but did result in reduced admission of the sickest patients to the ICU and increased transfer of critically ill patients to other hospitals.
Taking olive oil supplements may counteract some of the adverse cardiovascular effects of exposure to air pollution, according to a new study presented at the 2014 American Thoracic Society International Conference.
Patients who have survived a stay in the intensive care unit (ICU) have a greatly increased risk of developing symptoms of post-traumatic stress disorder (PTSD), according to a new study presented at the 2014 American Thoracic Society International Conference.
After a year of being treated with a novel drug, patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH) and those with persistent or recurrent pulmonary hypertension after an operation for the disease showed sustained improvement in a multicenter, international trial presented at the 2014 American Thoracic Society International Conference.
Children who are exposed in utero to high levels of particulate air pollution during the second trimester of pregnancy may be at greater risk of developing asthma in early childhood, according to a new study presented at the 2014 American Thoracic Society International Conference.
Researchers in separate clinical trials found two drugs slow the progression of idiopathic pulmonary fibrosis, a fatal lung disease with no effective treatment or cure, and for which there is currently no therapy approved by the Food and Drug Administration.
Despite being touted by their manufacturers as a healthy alternative to cigarettes, e-cigarettes appear in a laboratory study to increase the virulence of drug- resistant and potentially life-threatening bacteria, while decreasing the ability of human cells to kill these bacteria
Although it’s present in only a tenth of all patients who are admitted to the hospital, sepsis contributes to up to half of all hospital deaths in the U.S., according to a study presented at the American Thoracic Society’s annual conference here.
If you suffer from COPD, staying cool this summer may provide much more significant benefits than simply feeling more comfortable. A study from researchers at Johns Hopkins University says it may also keep you healthier. The study found COPD patients who were exposed to warm indoor temperatures had greater disease-related morbidity, including an increase in symptoms, a rise in the use of rescue medications and a decline in lung function. Higher outdoor temperatures were also associated with increased COPD symptoms.
ATS 2014, SAN DIEGO ─ Clinically important sleep apnea is common among survivors of acute respiratory failure, according to a new study presented at the 2014 American Thoracic Society International Conference.
ATS 2014, SAN DIEGO ─ A new study by researchers from California and Canada indicates a simple urine test can indicate the presence of venous thromboembolism, a blood clot that has broken free from its point of origin and which travels through the bloodstream, eventually lodging in a vein. The test evaluates the levels of fibrinopeptide B (FPB), a small peptide that’s released when a thrombosis forms and which is removed from the body through urine.
Patients with chronic pulmonary thromboembolic disease may benefit from pulmonary thromboendarterectomy (PTE), even if the patients don’t have severe pulmonary hypertension, according to University of California, San Diego, researchers.
ATS 2014, SAN DIEGO ─ As if increased risks of high blood pressure, respiratory infections, lung cancer and even depression weren’t enough, researchers say patients with chronic obstructive pulmonary disease (COPD) have another complication to worry about: heart failure.
Results of a Phase 3 study of ataluren in patients with nonsense mutation cystic fibrosis (nmCF) were published in Lancet Respiratory Medicine. Results demonstrated positive trends in both the primary endpoint, lung function as measured by relative change in % predicted FEV1 (forced expiratory volume in one second) and in the secondary outcome measure, rate of pulmonary exacerbations.
Young adults who smoked water pipes in hookah bars had elevated levels of nicotine, cotinine, tobacco-related cancer-causing agents, and volatile organic compounds (VOC) in their urine, and this may increase their risk for cancer and other chronic diseases, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
A team led by Maciej Goniewicz of Roswell Park Cancer Institute found that high-voltage electronic cigarettes may expose users to increased levels of toxic chemicals, including formaldehyde and acetaldehyde.
A new study from the University of Iowa reports Iowa's air quality falls within government guidelines for cleanliness, based on data gathered at five locations statewide. The study analyzed air quality and pollution sources in the state and is the first to compare air quality in urban versus rural areas. Results appear in the journal Environmental Science: Processes and Impacts.
Researchers have discovered a new gene expression mechanism in porcine reproductive and respiratory syndrome, or PRRS, virus — an important swine pathogen that costs the U.S. pork industry more than $600 million a year. The discovery provides a new avenue for scientists to explore strategies to control and prevent the disease.
The American Society for Radiation Oncology (ASTRO) is concerned by the Medicare Evidence Development and Coverage Advisory Committee’s (MEDCAC) April 30, 2014 recommendation to the Centers for Medicare and Medicaid Services (CMS) that adults at high risk for lung cancer should not receive Medicare coverage of annual, low-dose computed tomography (LDCT) screening.
Acute respiratory distress syndrome is a leading cause of respiratory failure after surgery. Patients who develop the lung disorder postoperatively are at higher risk of dying in the hospital, and those who survive the syndrome may still bear its physical effects years later. A Mayo Clinic-led study is helping physicians better identify patients most at risk, the first step toward preventing this dangerous and costly surgical complication. They found nine independent risk factors, including sepsis, high-risk aortic vascular surgery, high-risk cardiac surgery, emergency surgery, cirrhosis of the liver, and admission to the hospital from a location other than home, such as a nursing home.
Ginseng can help treat and prevent influenza and respiratory syncytial virus (RSV), a respiratory virus that infects the lungs and breathing passages, according to research findings by a scientist in Georgia State University’s new Institute for Biomedical Sciences.
The drug sirolimus can slow the lung disease LAM, while also causing potentially fatal complications after lung transplants. But research suggests a drug similar to sirolimus may be safe for LAM patients waiting for transplants.
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