If you’re looking for an indoor space with a low level of particulate air pollution, a commercial airliner flying at cruising altitude may be your best option. A newly reported study of air quality in indoor spaces such as stores, restaurants, offices, public transportation — and commercial jets — shows aircraft cabins with the lowest levels of tiny aerosol particles.
In a new article published in Cancer Immunology Research, the Moffitt team shows that sequential administration of immunotherapy followed by targeted therapy prolongs anti-tumor responses in preclinical models and may be a potential treatment option for patients with advanced melanoma.
Scientists have discovered that physically confined spaces can make for more efficient chemical reactions.
Keeping backyard chickens was already on the rise, and the hobby has become even more popular during the COVID-19 pandemic. Now, a University of Georgia researcher cautions that the practice has risks not just for chickens, but for wildlife and people as well.
According to a new study led by Yale Cancer Center and Department of Neurology researchers, a simple blood draw may be the first step in helping to discover tumor reactive immune or T cells to treat advanced melanoma, a deadly form of skin cancer. The findings were published today in the Journal of Experimental Medicine.
Researchers at the University of California San Diego School of Medicine and Massachusetts General Hospital have identified a new drug that could prevent Alzheimer’s disease by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques in the brain. The study, which will be published March 2 in the Journal of Experimental Medicine (JEM), demonstrates that the drug is safe and effective in rodents and monkeys, paving the way for future clinical trials in humans.
Researchers have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders. This preclinical research paves the way to develop more tailored treatment options for patients with inherited mitochondrial disease and acquired energy disorders.
Parent depression and stress early in the pandemic negatively contributed to young children's home education and anxiety, a University of Michigan study suggests.
Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.
Women and the Global South are strikingly underrepresented Most publications in leading scientific journals are by male authors from English-speaking countries. This changes only slowly, according to a recent study on diversity in top authorship, concludes Bea Maas from the University of Vienna. Her new study examines the (non-existent) diversity in top authorship in science.
Rapid COVID-19 tests are on the rise to deliver results faster to more people, and scientists need an easy, foolproof way to know that these tests work correctly and the results can be trusted. Nanoparticles that pass detection as the novel coronavirus could be just the ticket. Such coronavirus-like nanoparticles, developed by nanoengineers at the University of California San Diego, would serve as something called a positive control for COVID-19 tests.
A first-of-its-kind analysis of parents’ reviews of U.S. public K–12 schools, posted primarily from 2009 to 2019 on the popular school information site GreatSchools.org, found that most reviews were written by parents at schools in affluent neighborhoods and provided information that correlated strongly with test scores, a measure that closely tracks race and family income. Language associated with school effectiveness, which measures how much students improve in their test scores over time and is less correlated with demographics, was much less used.
A novel computer algorithm that could create a broadly reactive influenza vaccine for swine flu also offers a path toward a pan-influenza vaccine and possibly a pan-coronavirus vaccine as well, according to a new paper published in Nature Communications.
Black players in the NBA have 30% greater odds of leaving the league in any given season than white players who have equivalent performance on the court, a new study finds.
Researchers used delayed near-infrared imaging with high-dose indocyanine green (called “second window ICG” or “SWIG”) in the identification of brain metastases during surgery. They found that SWIG can be used to predict the extent of gross-total resection and progression-free survival in these cases.
A team of researchers co-led by Michael Frohman, MD, PhD, of Stony Brook University, has identified an important cause of congenital heart disease. They discovered that certain loss of functions in the PLD1 (Phospholipase D1) gene causes congenital right-sided cardiac valve defects and neonatal cardiomyopathy.
Peter Chen, MD, remembers those early days of March 2020 as one of swirling hyperactivity in the intensive care unit he leads at Cedars-Sinai. Chen and his team were struggling to respond to an emerging health crisis that was quickly growing into a global pandemic.
Alcohol and tobacco sales climb during early months of COVID-19 pandemic. Keck Medicine of USC study notes more dramatic increases among younger adults, ethnic minorities, those with younger children and/or large families and those with higher incomes
A repurposed drug used to treat arthritis did not significantly improve the outcomes of patients with severe COVID-19 pneumonia. Tocilizumab did not significantly improve clinical status or mortality rate at 28 days for participants who received it compared to a placebo.
Pharmaceutical companies get special protection from the FDA for orphan drugs aimed at rare diseases, but a study shows high spending for common diseases for some such drugs. Just 21% of the total dollars spent in 2018 on 15 top-selling partial orphan drugs went to the treatment of rare diseases, while more than 70% went to the treatment of common diseases.
Using cannabis for relief from migraine headache may be associated with developing “rebound” headache, or medication overuse headache, which occurs when pain medication is overused by patients who have an underlying primary headache disorder such as migraine, according to a preliminary study released today March 1, 2021, that will be presented at the American Academy of Neurology’s 73rd Annual Meeting being held virtually April 17 to 22, 2021.
While managed care has become the predominant form of Medicaid coverage for youth, researchers found only a modest increase in the receipt of preventive care services in this population, with marked variation across states. Whereas some states experienced improvements in preventive care services delivery for children as they implemented managed care, others did not.
The COVID-19 pandemic has heaped additional financial strains, childcare complications and other problems on already-burdened caregivers of children diagnosed with cancer, according to a study from researchers at Duke Health and other institutions.
What can you see on this picture (next to thearticle)? Say what comes to your mind immediately!
Researchers have developed an insight that could facilitate production of microscopic carbon nanotubes, structures thousands of times thinner than a human hair used in everything from microchips to sporting goods to pharmaceutical products.
A new article published online in the Journal of the American College of Radiology (JACR®) explains how patients recently vaccinated for COVID-19 can experience false-positive imaging exams and outlines steps providers can take to reduce unwarranted follow-up care for these findings.
Major changes in bereavement care have occurred during the COVID-19 pandemic, amid a flood of demand for help from bereaved people, according to new research from the University of Cambridge. The first major study of pandemic-related changes in bereavement care has found that the switch to remote working has helped some services to reach out, but many practitioners feel they do not have capacity to meet people's needs.
Duke researchers describe a new vaccination strategy that they think could re-program the body to fight off the bacteria that cause urinary tract infections.
Scientists developed a highly efficient, targeted method for delivering gene editing machinery to specific tissues and organs, demonstrating the treatment of high cholesterol by targeting genes in the liver of mice, reducing cholesterol for over 3 months (and potentially more) with one treatment
A new paper by Dr. Miki Ben-Dor and Prof. Ran Barkai from the Jacob M. Alkow Department of Archaeology at Tel Aviv University proposes an original unifying explanation for the physiological, behavioral and cultural evolution of the human species, from its first appearance about two million years ago, to the agricultural revolution (around 10,000 BCE).
In this study, among Caribbean-born individuals with breast and ovarian cancer, 1 in 7 had hereditary breast and ovarian cancer. The proportion of hereditary breast and ovarian cancer varied by island and each island had a distinctive set of variants.
Benign bone tumors may be present in nearly 20 percent of healthy children, based on a review of historical radiographs in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team led by UT Southwestern reports in a new study. The findings, published online in PNAS, could offer a new way to treat both Type 1 and Type 2 diabetes in people.
A new study finds that tiger mothers in the Russian Far East tend to be stay-at-home moms, and when it comes time for kids to move out, they sometimes let a few of them hang around at home.
Researchers have developed new 4D hydrogels — 3D materials that have the ability to change shape over time in response to stimuli — that can morph multiple times in a preprogrammed or on-demand manner in response to external trigger signals.
A team of international researchers led by a Florida State University assistant professor has analyzed reams of data from the Neolithic to Late Roman period looking at migration patterns across the Mediterranean and found that despite evidence of cultural connections, there’s little evidence of massive migration across the region.
Childhood cancer and its treatment can result in cognitive struggles. St. Jude scientists are studying the risk factors.
Studies representing nearly 2 million adults worldwide show that eating about five daily servings of fruits and vegetables, in which 2 are fruits and 3 are vegetables, is likely the optimal amount for a longer life, according to new research published today in the American Heart Association’s flagship journal Circulation.
Raspberry muffins are in our future.
Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago found that a region within the DNA of the cancer-promoting GLI1 gene is directly responsible for regulating this gene’s expression. These findings, published in the journal Stem Cells, imply that this region within GLI1 could potentially be targeted as cancer treatment, since turning off GLI1 would interrupt excessive cell division characteristic of cancer.
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