The developmental period from adolescence to adulthood is accompanied by a greater vulnerability to addictions – including alcohol use disorders – than is seen in other periods of life. This increased risk may be due to genetic predisposition, poor impulse control, or heightened sensitivity of the still-developing brain to drug-related toxicity. This report describes a study in mice of the neurobehavioral impact of chronic, intermittent alcohol-vapor exposure during adolescence, in an effort to model periodic heavy drinking and compare it with similar drinking behavior during adulthood.
“Acculturation” occurs when members of one cultural group adopt the beliefs and behaviors of another group. Research on alcohol use among Latino populations often focuses on acculturative processes and associated stressors that influence drinking. This review investigated how effective a measure of acculturation is at predicting several drinking behaviors among Latinos.
Medications can help people who drink excessive amounts of alcohol. One medication that can reduce alcohol craving and help promote recovery is naltrexone, which is approved for treatment of alcohol dependence by the Food and Drug Administration. It is available in two forms – injectable and oral. This pilot study evaluated the feasibility of injectable versus oral naltrexone, administered in a hospital setting to enhance treatment compliance when patients leave the hospital.
Monitoring changes in drinking patterns and amounts helps researchers, prevention professionals, and treatment providers plan for and respond effectively to personal and public harms associated with alcohol consumption. This information is particularly important for young adults, who tend to drink large amounts of alcohol and are thus at higher risk for negative consequences such accidents. This study examined historical changes in binge (5+ drinks per occasion) and high-intensity (10+, 15+ drinks per occasion) drinking among U.S. 12th graders and young adults from 2005 to 2015.
They have what most would want – affluent upwardly mobile parents, living in comfortable homes in the suburbs, going to an elite high school and being groomed for the nation’s best colleges. But these “privileged” American high schoolers can be at high risk for problematic substance abuse across early adulthood, according to new research from Arizona State University.
Brain changes after stroke may lead to increase in alcohol-seeking behavior, at least in animal models, according to research published Wednesday in the journal Scientific Reports.
Patients with hepatitis C who suffer from advanced stages of liver disease have renewed hope, thanks to findings by researchers who have discovered that a new drug significantly reduces their risk of death and need for transplantation.
Drinking just one glass of wine or other alcoholic drink a day increases breast cancer risk, finds a major new report by the American Institute for Cancer Research (AICR) and the World Cancer Research Fund (WCRF).
Liver cirrhosis is the 12th leading cause of mortality worldwide and approximately half of those deaths are due to alcohol abuse. Yet apart from alcohol abstinence, there are no specific treatments to reduce the severity of alcohol-associated liver disease. Researchers at University of California San Diego School of Medicine and J. Craig Venter Institute (JCVI) have linked intestinal fungi to increased risk of death for patients with alcohol-related liver disease.
A new study suggests that fetal alcohol exposure (FAE) reduces the taste system’s responsiveness to the bitter flavor and burning sensation of many varieties of alcoholic beverages. These factors make alcohol unappealing to some people, but, for reasons that are unclear, are less of a deterrent in young people exposed to alcohol before birth.
Neighborhoods with greater poverty and disorganization may play a greater role in problem drinking than the availability of bars and stores that sell hard liquor, a University of Washington-led study has found.
The startle response, often recorded as an eye-blink reflex, is a defensive measure believed to reflect emotional processing. Patients with alcohol use disorders (AUDs) show abnormal startle-reflex responses to alcohol-related stimuli. This study examined startle-reflex responses to various visual stimuli among heavy drinkers, and assessed whether certain patterns predict the development of AUDs four years later.
A new study led by the University of Delaware found that kids who are bullied in fifth grade often suffer from depression and begin using alcohol and other substances years after the initial incidents.
Mothers smoking crack cocaine during pregnancy—and its lingering effects on their children—are the focus of 20-plus years of ongoing research by Case Western Reserve University
In findings published in the journal Cancer, Epidemiology, Biomarkers & Prevention, UNC Lineberger Comprehensive Cancer Center researchers confirmed the link between alcohol consumption and breast cancer risk in a study in black women. The association has been seen in other studies drawn from majority white populations.
Less than half of Americans can recognize anxiety. Most people don’t know what to do about depression even when they spot it. And nearly 8 in 10 don’t recognize prescription drug abuse as a treatable problem.
University of Illinois at Chicago researchers are conducting a study to determine whether binge drinking is related to cardiovascular disease in young adults who are not predisposed to the condition.
According to new research published online in the Journal of the American Academy of Dermatology, increased consumption of alcohol, particularly white wine and liquor, is associated with a higher risk of rosacea in women.
Binge drinking tends to be lower among African Americans and Hispanics than non-Hispanic Whites. However, among older adult populations, minority groups are at higher risk for binge drinking. This study examined whether there was a “crossover effect” – with risk increasing from low to high as a function of age and income among three U.S. populations.
It has been shown that both heavy and occasional drinking among the general population are linked to eating less fruits and vegetables, and eating more processed and fried meat. This is particularly worrisome for pregnant women, as both drinking and inadequate nutrition can have adverse consequences for the fetus. This study investigated links between maternal diet and drinking during pregnancy.
A new study led by scientists at The Scripps Research Institute (TSRI) could help researchers develop personalized treatments for alcoholism and alcohol use disorder.
People drink alcohol for a number of reasons. This study focused on understanding why people drink and the consequences of their drinking. First, researchers identified “clusters” of drinkers in New Zealand, based on how much alcohol they drank, their beverage of choice, and a preference for public or private drinking locations. Second, it investigated the relations among drinker types and harms experienced, and considered their policy implications.
Mothers who binge drink before they become pregnant may be more likely to have children with high blood sugar and other changes in glucose function that increase their risk of developing diabetes as adults, according to a new study conducted in rats. The results will be presented Sunday at the Endocrine Society’s 99th annual meeting in Orlando, Fla.
What’s a tried-and-true way to prepare for surgery and anesthesia? By paying close attention to the healthcare professionals who will be delivering your care and providing them with essential information about your health status, history, and habits.
Most older Americans drink alcohol. Given that this segment of the population is projected to almost double by 2050, reaching 112 million, in the future, there will likely be many more older drinkers in the United States than currently. Importantly, older individuals are more sensitive to alcohol’s effects than their younger counterparts, and are also more likely to take prescription medications that can interact negatively with alcohol, potentially leading to falls and other injuries. This study examined trends in drinking status among U.S. adults 60 years of age and older.
Despite greater awareness of the dangers of prenatal exposure to alcohol, the rates of Fetal Alcohol Spectrum Disorders remain alarmingly high. This study evaluated academic achievement among children known to be prenatally exposed to maternal heavy alcohol consumption as compared to their peers without such exposure, and explored the brain regions that may underlie academic performance.
A survey of more than 422,000 college freshmen found that students who identified as transgender were more likely than their cisgender peers to experience negative consequences from drinking, including memory blackouts, academic problems and conflicts such as arguments or physical fights.
Although college can be demanding for young adults, it may be particularly so for transgender students struggling with identity-formation and other emotional, social, and developmental challenges. Prior research suggests that transgender students may experience greater drinking and negative alcohol-related consequences than their cisgender peers (i.e., those whose gender matches their sex at birth). This study examined levels of drinking, frequency of blackouts and other alcohol-related consequences, and drinking motivations among transgender college students.
Veterans who have drug or alcohol problems are more than twice as likely to die by suicide as their comrades, a new study finds. And women veterans with substance use disorders have an even higher rate of suicide -- more than five times that of their peers, the research shows.
Stress and anxiety are widely believed to contribute to drinking. Alcohol is thought to reduce tension caused by stress (the “flight or fight” response) as well as alleviate the unpleasant symptoms of anxiety (anticipation of the unpredictable, impending threats). Prior research, however, has yielded inconsistent findings as to the unique relations between stress and anxiety, on the one hand, and alcohol consumption and alcohol use disorders, on the other hand. This study was designed to examine how differences in self-reported levels of anxiety, anxiety sensitivity, and perceived stress impact the frequency and intensity of drinking, alcohol craving during early withdrawal, and alcohol craving and stress reactivity.
The study, “Pregnancy Intention and Maternal Alcohol Consumption,” found that the vast majority of women with intended as well as unplanned pregnancies either stopped or decreased drinking after having a positive pregnancy test.
The need to belong and experience social connections is a fundamental human characteristic. Prior research has shown that social rejection is linked to increases in negative emotions, distress, and hostility. This study examined the impact of social rejection on alcohol use, and whether the impact differed when the social rejection was by close others, such as friends, spouses or family members, or by strangers or acquaintances.
People with intermittent explosive disorder (IED)—a condition marked by frequent physical or verbal outbursts—are at five times greater risk for abusing substances such as alcohol, tobacco and marijuana than those who don’t display frequent aggressive behavior, according to a new study by researchers from the University of Chicago.
Although counterfeit alcohol is a new phenomenon in most of the world, it has been a longstanding problem in Russia. In 2002, illegal commercial alcohol products totaled more than half of the alcohol retail turnover in that country. More recently, an economic recession has reactivated illicit markets in Russia. While the demand for lower-priced counterfeit alcohol is often linked to economic disadvantages, this research examined whether the problem is more complicated.
Underage youth are nearly twice as likely to recall seeing alcohol marketing on the internet than adults, with almost one in three saying they saw alcohol-related content in the previous month, according to a new pilot survey led by the Johns Hopkins Bloomberg School of Public Health.
Taking one oxycodone tablet together with even a modest amount of alcohol increases the risk of a potentially life-threatening side effect known as respiratory depression, which causes breathing to become extremely shallow or stop altogether, reports a study published in the Online First edition of Anesthesiology.
Hyperalgesia refers to an increased sensitivity to pain. It can occur during alcohol withdrawal, and may contribute to a relapse to drinking. Alternative therapies such as acupuncture and electroacupuncture (EA; which combines acupuncture with electrical stimulation) are effective in reducing pain and, possibly, alcohol-withdrawal symptoms. This rodent study investigated whether EA can alleviate hyperalgesia during alcohol withdrawal, potentially reducing the risk of a relapse to drinking, and whether it achieves this effect via action at mu opioid receptors (MORs) located in a brain region called the lateral habenula.
Cytokines are small proteins in the immune system that act as chemical messengers between cells. Prior research suggests that pro- and anti-inflammatory cytokines are dysfunctional during alcohol dependence and may contribute to the progression from healthy to problem drinking. This study compared social and non-dependent problem drinkers on the impact of alcohol-related changes in the body’s immune response to stress, alcohol-cue induced craving and anxiety, motivation to drink, and alcohol consumption.
A new clinical guideline from the American College of Gastroenterology offers the first recommendations in over 10 years on the evaluation of abnormal liver chemistries. For the first time in a liver test guideline, the authors define a normal healthy serum alanine aminotransferase (ALT) level for women and men (up to 25 IU/L for women, up to 33 IU/L for men) and recommend that levels above this should be assessed by physicians.
Nationwide, the mortality rate from deaths caused by drugs, alcohol and suicide rose 52 percent from 2000 to 2014, according to new research from the Carsey School of Public Policy at the University of New Hampshire. Most of the increase was driven by a surge in prescription opioid and heroin overdoses.
Adolescents who are violent toward their romantic partners are also more likely to think about or attempt suicide, carry a weapon, threaten others with a weapon and use drugs or alcohol than peers in non-violent relationships, according to new research from the University of Georgia.
Posttraumatic stress disorder (PTSD) can develop after a traumatic event or events. Although it is most often associated with military personnel exposed to the trauma of combat, it can also disproportionately affect vulnerable American Indian and Alaskan-Native (AI/AN) populations. Because alcohol use disorders (AUDs) also have a disproportionate impact on AI/ANs, this study compared both lifetime PTSD and past-year AUD among AI/ANs and non-Hispanic Whites (NHWs).
Alcohol use can be found in suicide deaths and unintentional deaths due to injuries such as those from motor vehicle collisions (MVCs). The authors of this study argue that it is important to distinguish between the roles that alcohol may play in the two different types of deaths. Consequently, they compared postmortem toxicology results for alcohol and other drugs, alone and in combination, in suicide and MVC deaths.