Value in Health, the official journal of ISPOR (the professional society for health economics and outcomes research), announced today the publication of new research suggesting that while payers recognize the value of real-world evidence, the use of such studies to inform pharmacy and therapeutic (P&T) committee decisions is limited.
Few older adults use medical marijuana, a new national poll finds, but the majority support its use if a doctor recommends it, and might talk to their own doctor about it if they developed a serious health condition. And two-thirds say the government should do more to study the drug’s health effects.
Differences between signed and spoken languages are significant, yet the underlying neural processes we use to create complex expressions are quite similar for both, a team of researchers has found.
Rear-facing car seats have been shown to significantly reduce infant and toddler fatalities and injuries in frontal and side-impact crashes, but they’re rarely discussed in terms of rear-impact collisions. Since rear-impact crashes account for more than 25 percent of all accidents, researchers at The Ohio State University Wexner Medical Center conducted a new study to explore the effectiveness of rear-facing car seats in this scenario.
By Kerry Bennett Office of the Vice President for ResearchA new study published in Nature Physics describes how a team of scientists used a laser beam to gain access to long-lived sound waves in crystalline solids as the basis for a potentially new approach to information processing and storage. One of Northern Arizona University’s newest physicists, assistant professor Ryan Behunin, is a co-author of the study.
A group of Penn researchers hopes to improve the understanding of these present-day ailments by looking at the very engine of evolution: natural selection in humans.
The composition of bacteria in the gastrointestinal tract may hold clues to help predict which cancer patients are most apt to benefit from the personalized cellular therapies that have shown unprecedented promise in the fight against hard-to-treat cancers.
Hospital payment experiment in Maryland failed to deliver on the promise of shifting care from hospitals toward less expensive outpatient and primary care settings. Researchers say that weak incentives for physicians may have limited the program’s effectiveness.
A new study from the Johns Hopkins Bloomberg School of Public Health found that the uninsured face significant barriers to primary care, highlighting a group that remains vulnerable even after the Affordable Care Act insurance expansions. With trained auditors depicting low-income new uninsured patients, the study found that fewer than one in seven could confirm an office visit occurred if they were required to make payment arrangements to cover the cost of the visit.
Earth has had moderate temperatures throughout its early history, and neutral seawater acidity. This means other rocky planets could likely also maintain this equilibrium and allow life to evolve.
One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune system, new research suggests.
Rising drug prices have gotten a lot of attention lately, but the actual cost of prescription medications is more than just the bill. Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego estimate that illness and death resulting from non-optimized medication therapy costs $528.4 billion annually, equivalent to 16 percent of total U.S. health care expenditures in 2016. The analysis is published March 26 by Annals of Pharmacotherapy.
A range of less than one degree Fahrenheit (or half a degree Celsius) of climate warming over the next century could make all the difference when it comes to the probability of future ice-free summers in the Arctic.
Patients treated for heart attack were 48 percent less likely to have a sudden return to the hospital when educated using a multi-factored discharge and follow-up program
Columbia Engineering researchers have found that vegetation plays a dominant role in Earth’s water cycle, that plants will regulate and dominate the increasing stress placed on continental water resources in the future. “This could be a real game-changer for understanding changes in continental water stress going into the future,” says Prof. Pierre Gentine. In this paper, he demonstrates vegetation’s key role in responding to rising CO2 levels and shows how plants will regulate future dryness.
In the tiny brain space where two nerve cells meet, chemical and electric signals shuttle back and forth, a messaging system that ebbs and flows in those synaptic spaces, sometimes in ways that scientists believe aid and abet learning and memory. But because most of the proteins found in those synapses die and renew themselves so rapidly, scientists have had a hard time pinning down how synapses are stable enough to explain the kind of learning and memory that lasts a lifetime.
Prescription drug consumers confounded by the cost of their medications can get a peek behind the curtain thanks to new Washington University in St. Louis research into the complex “co-opetition” — cooperation and competition — among drug makers in the middleman-controlled US drug supply chain.But, as explained by Panos Kouvelis, the Emerson Distinguished Professor of Operations and Manufacturing Management at Olin Business School and director of The Boeing Center for Supply Chain Innovation, the system is so complex and opaque, it may be headed for government regulation.
Story tips: ORNL-led team cultivated a novel oral microbe in adults with periodontitis; ORNL partnered with FCA US and Nemak to develop a new cast aluminum alloy for engine cylinder heads, which could lead to better fuel efficiency; ORNL studies cast doubt on 40-year-old theory describing how plastic polymers behave during processing.
Physicists have identified a new state of matter whose structural order operates by rules more aligned with quantum mechanics than standard thermodynamic theory.
The vast majority of genetic mutations associated with cancer occur in non-coding regions of the genome, yet it’s unclear how they may influence tumor development or growth. Researchers at University of California San Diego School of Medicine and Moores Cancer Center identified nearly 200 mutations in non-coding DNA that play a role in cancer. Each mutation could represent a new cancer drug target.
Babies who died during their sleep while being watched by someone other than parents often had been placed in unsafe sleep positions, such as on their stomachs, or in unsafe locations, such as a couch, a new study has found.
Más del 50 por ciento de los médicos en Estados Unidos dicen sentir agotamiento en su trabajo. Por ello, Mayo Clinic y otros centros médicos principales publicaron hoy una “carta estatutaria para el bienestar de los médicos.”
Physicians who receive negative reviews online do not receive similar responses in rigorous patient satisfaction surveys, according to new Mayo Clinic research in Mayo Clinic Proceedings. Yet, compared with colleagues without negative reviews, they score lower on factors that go beyond patient interactions and are beyond their immediate control.
More than halfway across the universe, researchers have spotted the farthest individual star ever seen.
Scientists have directly measured the increasing greenhouse effect of methane at the Earth’s surface for the first time. A research team from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) tracked a rise in the warming effect of methane – one of the most important greenhouse gases for the Earth’s atmosphere – over a 10-year period at a DOE field observation site in northern Oklahoma.
A team led by scientists at Van Andel Research Institute (VARI) and Cedars-Sinai have developed a straightforward, computational way to measure cellular age, a feat that may lead to better, simpler screening and monitoring methods for cancer and other diseases.
Exposing infants to antacids or antibiotics in their first six months of life could increase their risk of developing allergies in childhood.
A team of computational biologists has developed an algorithm that can ‘align’ multiple sequencing datasets with single-cell resolution. The new method has implications for better understanding how different groups of cells change during disease progression, in response to drug treatment, or across evolution.
Using the Hubble Space Telescope and a quirk of nature called gravitational lensing, an international team of astronomers has found the most distant individual star ever discovered, dubbed "Icarus." This discovery provides new insight into the formation and evolution of stars in the early universe, the makeup of galaxy clusters, and the nature of dark matter.
A new study from a University of Iowa-led research team finds that women who are considering pregnancy would benefit from greater fitness. Using 25 years of data on pre-pregnant women, the researchers report that higher levels of pre-pregnancy fitness are associated with a reduced risk of developing gestational diabetes.
Adults with diabetes are less likely to visit the dentist than people with prediabetes or without diabetes, finds a new study led by researchers at NYU Rory Meyers College of Nursing and East Carolina University’s Brody School of Medicine.
Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis. The study, published today in Oncogene, represents significant progress in the clinical translation of previous basic scientific discoveries.
American clinicians rated white patients as significantly more likely to improve and more likely to adhere to recommended treatments than black patients, and to be more personally responsible for their health than black patients.
Alzheimer’s, Parkinson’s and Huntington’s disease may have more in common than their effects on the functions of the brain and spinal cord. And finding that common thread could lead to a treatment that could work for all three.
A groundbreaking study of nearly 4,000 trauma patients evacuated from the frontlines in Afghanistan over a six-year period offers insight that can inform decisions on team composition, staff training and skill mix on the battlefield and beyond. The study is one of several articles on en route care published in the April 2018 issue of Critical Care Nurse.
We’ll pay more for unhealthy foods when we crave them, new neuroscience research finds. The study also shows that we’re willing to pay disproportionately more for higher portion sizes of craved food items.
In the search for extraterrestrial life, scientists have turned over all sorts of rocks. Mars, for example, has geological features that suggest it once had — and still has — subsurface liquid water, an almost sure prerequisite for life. Scientists have also eyed Saturn’s moons Titan and Enceladus as well as Jupiter’s moons Europa, Ganymede and Callisto as possible havens for life in the oceans under their icy crusts. Now, however, scientists are dusting off an old idea that promises a new vista in the hunt for life beyond Earth: the clouds of Venus.
Urothelial cancers of the bladder and upper urinary tract are among the most common cancers encountered worldwide. Now an international team of cancer researchers have developed a highly sensitive and specific non-invasive test as a biomarker for early detection of urothelial cancers. Details of this method known as UroSEEK, are published in eLife.
A slippery rough surface (SRS) inspired by both pitcher plants and rice leaves outperforms state-of-the-art liquid-repellent surfaces in water harvesting applications, according to a team of researchers at Penn State and University of Texas at Dallas.
Electronic systems, such as electric vehicles and large data centers, generate a lot of power, which creates tremendous heat. An engineer at Washington University in St. Louis has developed a unique evaporative cooling system using a membrane with microscopic pillars designed to remediate the heat, ultimately improving performance.
The use of mineral admixtures in concrete produced with treated recycled concrete aggregate enhances both the mechanical and durability properties leading to sustainable development.
It's called a nanoflower, but if you could brush your cheek against its microscopic petals, you would find them cool, hard, and...rusty. Common rust forms the inner skeleton of these lovely and intricate nanostructures, while their outer layer is a kind of plastic. Researchers at Washington University in St. Louis have developed a straightforward way to make this type of conducting polymer with high surface area that is likely to be useful for energy transfer and storage applications.
A first-of-its-kind drug targeting a fused gene found in many types of cancer was effective in 93 percent of pediatric patients tested, researchers at UT Southwestern’s Simmons Cancer Center announced.
A team of scientists from across the U.S. has found a new way to create molecular interconnections that can give a certain class of materials exciting new properties, including improving their ability to catalyze chemical reactions or harvest energy from light.
Nicotinomide riboside (NR) mimics caloric restriction, kick-starting the same pathways responsible for reducing cardiovascular aging.
People have become familiar with “bomb cyclones” this winter, as several powerful winter storms brought strong winds and heavy precipitation to the U.S. east coast, knocking out power and causing flooding. Scientists have extensively studied potential causes behind these year-to-year changes in attempt to better forecast storm tracks and their extreme impacts, but new research from scientists at the Stony Brook University School of Marine and Atmospheric Sciences, funded by NOAA Research’s MAPP Program, identifies another crucial controlling force.
Researchers at the University of Utah and Konkuk University found that news stories are perceived as biased based on who shares that story on social media, regardless if the actual story is biased.
Materials inspired by disappearing Hollywood dinosaurs and real-life shy squid have been invented by UCI engineers, according to new findings in Science this Friday.
Patients traveling to developing countries for plastic surgery procedures may experience severe complications—requiring extensive and costly treatment after they return to the United States, reports a study in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
One in 10 electronic dance music (EDM) party attendees have misused opioids in the past year, exceeding the national average, finds a study by the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU Meyers College of Nursing.
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