I am pleased to announce that the 8th Joint ACTRIMS-ECTRIMS Meeting will be held from September 11-13, 2020, with a special encore featuring Late-Breaking News and a COVID-19 Session on September 26.
Scientists at the La Jolla Institute for Immunology (LJI) have discovered a potential new way to better fight a range of infectious diseases, cancers and even autoimmune diseases. The new study, published recently in Nature Immunology, shows how a protein works as a “master regulator” in the immune system.
Nationally recognized rheumatology expert Francesco Boin, MD, has been appointed director of the division of Rheumatology and director of the new Scleroderma Program at Cedars-Sinai. Boin is an accomplished and widely published investigator of autoimmune diseases, with a reputation for clinical excellence and a multidisciplinary approach to patient care.
Mild thyroid abnormalities affect up to one in five women with a history of miscarriage or subfertility which is a prolonged time span of trying to become pregnant that hasn’t reached a year, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Dragana Odobasic, PhD, a research fellow at Monash University in Melbourne, Australia, was awarded the Vasculitis Foundation’s (VF) “Dr. Chris Cox-Marinelli Young Investigator Award” in May for her study, Tolerogenic Dendritic Cells for Antigen-Specific Immunosuppression in MPO-ANCA Vasculitis. The award, a one-year grant totaling $49,822, was created in memory of Chris Cox-Marinelli, MD, who was a strong advocate for promoting the development of junior investigators toward a career in vasculitis.
A UCLA research team has identified a new paradigm for understanding the regulation of the immune system, potentially paving the way for new approaches to treating infections and immune-related diseases such as type 1 diabetes and certain cancers.
Join the Vasculitis Foundation (VF) this Saturday, May 23, for a live Q&A webinar where vasculitis experts will discuss what they know about COVID-19 and immune-suppressed patients. The program starts at 9 a.m. Central Time.
A new Weizmann Institute model of autoimmune disease may solve some major outstanding riddles, including what causes T cells to attack and why only certain organs get the diseases
Variants in a gene of the human immune system cause men and women to have different vulnerabilities to the autoimmune diseases lupus and Sjögren’s syndrome, according to findings published in the journal Nature. The gene variants are a member of the complement system.
Elevated blood levels of toxic chemicals found in pesticides, nonstick cookware, and fire retardants have been tied to an increased risk for celiac disease in young people, new research shows.
New work led by researchers in the Blavatnik Institute at Harvard Medical School and at the Broad Institute of MIT and Harvard provides a clear genetic explanation behind the long-standing yet mysterious observation that some diseases occur more often, hit harder or elicit different symptoms in men or women.
The Race is On! That’s the theme for Vasculitis Awareness Month 2020, which runs May 1 through May 31, 2020, and shines a spotlight on vasculitis—a rare, but often serious autoimmune blood vessel disorder.
Although children don’t typically fall seriously ill from the new coronavirus, doctors in Europe are now expressing concern that children with COVID-19 have developed mysterious symptoms that mimic those appearing with Kawasaki disease.On the Pulse asked Dr. Michael Portman, pediatric cardiologist and director of the Kawasaki Disease Clinic at Seattle Children’s Hospital, to help break this emerging issue down for parents and caregivers.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.
Medications for lupus — a long-term autoimmune disease that occurs when a person’s immune system attacks different parts of their body, including their skin — are currently being explored as a treatment for COVID-19 patients. This may significantly limit access to the drugs by those who depend on it to manage their health conditions.
A new study co-led by scientists at the La Jolla Institute for Immunology (LJI) adds increasing evidence that Parkinson’s disease is partly an autoimmune disease. In fact, the researchers report that signs of autoimmunity can appear in Parkinson’s disease patients years before their official diagnosis.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.
Like a parent of teenagers at a party, Mother Nature depends on chaperones to keep one of her charges, the immune system, in line so that it doesn’t mistakenly attack normal cells, tissues and organs in our bodies. A recent study by Johns Hopkins Medicine researchers has demonstrated that in mice — and probably humans as well — one biological chaperone may play a key role in protection from such attacks, known as autoimmune responses, which are a hallmark of diseases such as multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus and type 1 diabetes.
Autoimmunity, a condition in which the body’s immune system reacts with components of its own cells, appears to be increasing in the United States, according to scientists at the National Institutes of Health and their collaborators.
There's a higher case fatality rate in type 1 than type 2 diabetes, which suggests different mechanisms for heart failure might be involved in type 1 diabetes.” Given the burden of heart failure in type 1 diabetes, the early identification of patients at particular risk is of importance.
Scientists at St. Jude Children’s Research Hospital mapped the epigenetic controls on T cells, which could aid Type 1 diabetes diagnosis and treatment, as well as cancer immunotherapy.
The following are various story ideas regarding the COVID-19 illness. To interview Johns Hopkins experts on these topics or others, contact [email protected].
The American College of Rheumatology (ACR) has released an official position statement concerning prior authorization for the approval of prescription medications, highlighting the significant burdens it creates for patients and rheumatology professionals. This process can result in a significant delay of care or treatments, treatment abandonment and potential harm to patients.
An international team of scientists, led by UC San Diego researchers, has developed a new, multi-sensor tool that measures subtle changes in multiple sclerosis patients, allowing physicians to more frequently and more quickly respond to changes in symptoms or patient condition.
Preclinical research shows a pivotal role for cellular metabolism to regulate the fate decision of CD4 T cells as they differentiate into either destructive Th17 cells that mediate chronic inflammation or regulatory Treg T cells, a decision that occurs very early in the activation of CD4 T cells.
Researchers at the University of Chicago have developed the first truly accurate mouse model of celiac disease. The animals have the same genetic and immune system characteristics as humans who develop celiac after eating gluten. This provides a vital research tool for developing and testing new treatments for the disease.
Researchers found, in mice, that changes in DNA sequence can trigger the chromosomes to misfold in a way that puts one at a heightened risk for Type 1 diabetes. The study revealed that differences in DNA sequences dramatically changed how the DNA was folded inside the nucleus, ultimately affecting the regulation of genes linked to the development Type 1 diabetes.
Patients with thyroid eye disease who used the minimally invasive insulin-like growth factor I blocking antibody, teprotumumab, experienced improvement in their symptoms, appearance and quality of life, according to a study recently published in The New England Journal of Medicine.
A new study finds that one side effect of lupus could also make patients with the autoimmune condition more vulnerable to a skin infection, or spreading the infection to others.
Um interruptor molecular tem a capacidade de ativar uma substância em animais que restauram danos neurológicos em distúrbios como esclerose múltipla, pesquisadores da Mayo Clinic descobriram.
Detroit, MI (January 30, 2019) - The American Autoimmune Related Disease Association (AARDA) is thrilled to announce our new partnership with AutoimmuneMom. For the last seven+ years, AutoimmuneMom has created a digital community through the hard work and dedication of Katie Cleary. Now, AARDA will proudly host the content that has brought together people with autoimmune disease through stories of how autoimmune disease impacts motherhood and pregnancy, general autoimmune information, personal stories, and doctor recommendations. AutoimmuneMom will continue to maintain its social media presence, but all website content will be hosted on AARDA.org.
Las células mesenquimales del estroma procedentes del tejido graso y de la médula ósea se emplean ampliamente en ensayos terapéuticos por sus cualidades antiinflamatorias, pero un nuevo estudio de Mayo Clinic descubre que las células hepáticas podrían ser más valiosas.
The Symposium on February 19 will feature a variety of clinical disorders in which prevention, screening, and treatment can be informed through genomic and epigenomic data.
What's your type?
That question could gain new meaning, thanks to scientists who've categorized how humans age into different classes dubbed "ageotypes," reports a new study from the Stanford University School of Medicine.
Common classroom activities – such as playing with Play-Doh or uncooked pasta – have little or no potential to cause harmful gluten exposure in children with celiac disease, reports a study in the Journal of Pediatric Gastroenterology and Nutrition (JPGN). Official journal of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) and the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, JPGN is published by Wolters Kluwer.
Could bile acids—the fat-dissolving juices churned out by the liver and gallbladder—also play a role in immunity and inflammation?
The answer appears to be yes, according to two separate Harvard Medical School studies published in Nature.
A first-of-its-kind study on molecular interactions by biomedical engineers in the University of Minnesota’s College of Science and Engineering will make it easier and more efficient for scientists to develop new medicines and other therapies for diseases such as cancer, HIV, and autoimmune diseases. The study resulted in a mathematical framework that researchers plan to use to develop a web-based app that other researchers can use to speed the development of new therapies for diseases.
if you’re traveling over the river and through the woods for the holiday, here are tips from Ritu Verma, MD, medical director of the University of Chicago Medicine Celiac Disease Center, to help keep your child who is living with celiac disease healthy and in the holiday spirit.
Scientists describe in Nature Immunology an entirely new molecular process in mice that triggers T cell-driven inflammation and causes different auto-immune diseases. In a study published online Dec. 17, researchers report their data have implications for Multiple Sclerosis, Type 1 diabetes and Inflammatory Bowel Disease. It also will help efforts to find better treatments for autoimmune disease, still an urgent need in medicine.
Cedars-Sinai today announced a $20 million gift from Dr. and Mrs. Min H. Kao and the Kao Family Foundation to create the Kao Autoimmunity Institute to advance research and treatment of rheumatologic diseases. The gift also will establish the Scleroderma Program within the institute to provide interdisciplinary and integrated care for scleroderma patients and to support research, outreach, training and education to help those with the disease.
Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.
In a new paper in Science Signaling, researchers at the University of Hyderabad in India and the Cornell University College of Veterinary Medicine show that a plant-based compound called halofuginone improves the immune response to a potential vaccine against dengue virus.
By identifying a molecule that delays the progression of MS, researchers pave the way for new therapies for the nearly 77,000 Canadians living with the disease.
New, late-breaking research discovered that there are significant associations between anti-citrullinated protein bodies (ACPA), a characteristic biomarker for rheumatoid arthritis (RA), and industrial emissions of fine particles matter and sulfur dioxide.
The American College of Rheumatology (ACR), in partnership with the Vasculitis Foundation (VF), is previewing new draft recommendations for the treatment of systemic vasculitis at the 2019 ACR/ARP Annual Meeting in Atlanta.
The American College of Rheumatology (ACR) is previewing draft recommendations from an updated treatment guideline for managing patients with gout during the 2019 ACR/ARP Annual Meeting in Atlanta.
According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, both patients with rheumatoid arthritis whose disease onset occurred at an older age and those whose disease onset occurred earlier in life have similar improvements in clinical disease at 48 weeks after starting biologic disease-modifying antirheumatic drugs, as well as similar drug maintenance and adverse events discontinuation rates.