A drug that's commonly used to treat high blood pressure is being repurposed for a rare tissue cancer in Europe. The medication, named propranolol, was recently granted Orphan Drug Designation by the European Commission (EC).
Investigators at the University of Utah have identified distinct differences in the hearts of advanced heart failure patients who have defied the odds and showed signs of recovery from the disease. Published online in the journal Circulation, the new findings could help clinicians identify the best candidates for cardiac recovery therapies.
Studies show that people who are chronically lonely have significantly more heart disease, are more prone to advanced cancers and strokes, and are more likely to develop neurodegenerative diseases such as Alzheimer’s.
The Council advises on matters relating to the cause, prevention, diagnosis and treatment of heart, blood vessel, lung and blood diseases; the use of blood and blood products and the management of blood resources; and on sleep disorders.
Researchers at the UCLA School of Nursing are addressing health challenges related to issues of the heart, the leading cause of death worldwide – from chronic health concerns faced by individuals born with congenital heart disease to those who are at risk or have developed cardiovascular disease.
Replacing biomass and kerosene cookstoves used throughout the developing world with clean-burning ethanol stoves may reduce hypertension and cardiovascular risk in pregnant women, according to new research published online, ahead of print in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
In a clinical trial in Nigeria that replaced biomass and kerosene cookstoves with clean-burning ethanol stoves, researchers were able to reduce by two-thirds the risk of high blood pressure and cardiovascular disease in pregnant women.
People who use cocaine regularly are at high risk of coronary artery disease. A study in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine (ASAM), reports that stopping or reducing cocaine use can potentially reverse the process of coronary atherosclerosis. The journal is published by Wolters Kluwer.
The Chronic Total Occlusion (CTO) Summit 2017 will feature the latest research and techniques available for interventional cardiologists in this emerging subspecialty of complex coronary artery disease. Now in its 14th year, the two-day course will take place February 23-24 at the New York Marriott Marquis.
Experts at Johns Hopkins and New York's Mount Sinai Health System have published a suggested new plan for a five-stage system of classifying the risk of heart attack in those with heart disease, one they say puts much-needed and long-absent focus on the risks faced by millions of Americans who pass so-called stress tests or have less obvious or earlier-stage danger signs.
A new global study projects that a government-supported intervention to reduce national salt consumption by 10 percent over 10 years would be a highly cost-effective “best buy” for preventing cardiovascular disease across 183 countries worldwide.
The University of Maryland Medical Center (UMMC) is now offering a simple genetic test to patients who receive heart stents to determine whether they have a genetic deficiency that affects how they respond to a common drug to prevent blood clots. Patients are typically given the medication, clopidogrel, to prevent cardiovascular events after having a stent placed in a coronary artery to treat a blockage.
Sudden cardiac death in patients with heart failure is a major concern in the United States. A Virginia Tech Carilion Research Institute team will investigate how the microscopic spaces surrounding heart cells affect connections called gap junctions.
Credentialed press representatives are invited to attend The Society of Thoracic Surgeons 53rd Annual Meeting, Exhibition, and Press Conference, which will include late-breaking scientific research, thought-provoking lectures, cutting-edge technologies, and innovative cardiothoracic surgery products—some that are not yet available on the market. Cardiothoracic surgeons and other health care experts also will provide an update on Mycobacterium chimaera infections related to heater-cooler devices used in cardiac surgery.
The lower a neighborhood’s socioeconomic status is, the more likely its black residents are to develop heart disease and stroke, according to a new Drexel University-led public health study.
Can a failing heart recover? For many years, the answer to that question was unequivocally “No.” But as the University of Utah School of Medicine’s annual Utah Cardiac Recovery Symposium (U-CARS) will explore on Jan. 12-13, advances in treating heart failure are giving physicians, surgeons and researchers reason to hope the deadly disease might one day be defeated. Watch the symposium live online at http://www.kaltura.com/tiny/guvl3
The UAB study, an updated meta-analysis of the use of implantable cardioverter-defibrillators for non-ischemic cardiomyopathy, provides further support to the current American Heart Association and American College of Cardiology guidelines and challenges the recently published DANISH trial
Regenerative medicine has much to offer the cardiovascular field, although there is still a way to go before it is ready for routine clinical application, according to Andre Terzic, MD, PhD, director of the Mayo Clinic Center for Regenerative Medicine and a professor in Cardiovascular Diseases Research at the Mayo Clinic, in Rochester, Minn.
The National Institutes of Health (NIH) is funding Canadian component of a study to determine the optimal amount of blood to transfuse in anemic patients who have suffered a myocardial infarction.
For the first time, researchers have developed tests that could improve treatment for heart failure patients by diagnosing the condition with greater accuracy, as well as by detecting the onset of congestive heart failure earlier. The findings were published in the Cardiovascular Disease issue of Clinical Chemistry, the journal of AACC.
Research published today in AACC’s Clinical Chemistry journal shows that a test can identify patients with a history of cardiovascular disease who are at high risk of another heart attack or death and would benefit from treatment with the drug vorapaxar. This study and two others on tests that predict risk of adverse cardiovascular events are featured in the Cardiovascular Disease issue of Clinical Chemistry.
Laboratory medicine experts are using a growing understanding of the molecular signatures of heart disease to develop more precise tests for the early diagnosis, monitoring, and targeted treatment of this condition. A special issue of Clinical Chemistry, the journal of AACC, titled “Cardiovascular Disease: Impact of Biomarkers, Proteomics, and Genomics,” highlights the groundbreaking medical tests that could advance patient care for this chronic disease and its consequences, which range from cardiac arrest to congestive heart failure.
Participants in Joslin's Why WAIT (Weight Achievement and Intensive Management) program lost substantial amounts of weight, and even those who maintained relatively little loss of weight after five years demonstrated reduced risks of cardiovascular disease.
People with any form of diabetes are at greater risk of developing cardiovascular conditions than people without the disease. Moreover, if they undergo an operation to open up a clogged artery by inserting a “stent” surgical tube, the artery is much more likely to clog up again. However, researchers at Joslin Diabetes Centers now have uncovered an explanation for why these procedures often fail, which may lead toward better alternatives.
The Affordable Care Act (ACA) instituted financial penalties against hospitals with high rates of readmissions for Medicare patients with certain health conditions. A new analysis led by researchers at Beth Israel Deaconess Medical Center (BIDMC), Harvard T.H. Chan School of Public Health and Massachusetts General Hospital has found that the penalties levied under the law’s Hospital Readmissions Reduction Program were associated with reduced readmissions rates and that the poorest performing hospitals achieved the greatest reductions.
Researchers have developed a synthetic version of a cardiac stem cell. These synthetic stem cells offer therapeutic benefits comparable to those from natural stem cells and could reduce some of the risks associated with stem cell therapies.
After all the lifting, hauling and wrapping, worn out gift givers may blame the season’s physical strain for any shoulder soreness they are feeling. It turns out there could be another reason. A new study led by investigators at the University of Utah School of Medicine finds that individuals with symptoms that put them at increased risk for heart disease could be more likely to have shoulder problems, including joint pain and rotator cuff injury.
When people with chronic health problems couldn't get around town to their doctors' appointments, a four-year Johns Hopkins program brought the appointments to them. Johns Hopkins cardiologist and senior director for accountable care Scott Berkowitz, M.D., has published an extensive report of a four-year, $19 million Centers for Medicare and Medicaid Services grant in the journal Healthcare.
A consortium directed by UCLA’s Dr. Kalyanam Shivkumar has received a three-year, $8.6 million grant from the National Institutes of Health to map the heart’s nervous system. The group’s goal: To conduct research that leads to new ways to treat cardiovascular disease by targeting nerves in the heart’s nervous system.
Using human embryonic stem cells to create a type of cardiac cells known as sinotrial (SA) node pacemaker cells, researchers have developed a biological pacemaker that overcomes many of the limitations of electrical pacemakers.
Transplant surgeons recently performed UT Southwestern Medical Center’s first heart/liver transplant – saving the life of a singer/musician from a small Texas town.
Current methods to predict the risk of heart attack and stroke vastly underestimate the risk in individuals with HIV, which is nearly double that of the general population, reports a new Northwestern Medicine study. “The actual risk of heart attack for people with HIV was roughly 50 percent higher than predicted by the risk calculator many physicians use for the general population,” said first author Dr.
Researchers at the University of Maryland School of Medicine (UM SOM) and the Interdisciplinary Stem Cell Institute (ISCI) at the University of Miami Miller School of Medicine have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome (HLHS).
Philanthropists Garry S. Sklar, MD, and his wife, Sarah Sklar, were recently honored by SUNY Downstate in recognition of gifts that support clinical care and research efforts in Anesthesiology and Cardiothoracic Surgery, as well as healthcare education through simulation technology.
For critically ill patients with heart or lung failure that does not respond to conventional treatments, extracorporeal life support (ECLS) can provide a bridge to survival. Updated analysis of a worldwide database finds that ECLS technologies are becoming more widely available and more frequently used at centers around the world, according to a report in the ASAIO Journal, published by Wolters Kluwer.
Announcement of a new clinical trial designed to measure the impact of transcatheter aortic valve replacement (TAVR) in low surgical risk patients with severe aortic stenosis (AS).
Using cardiac imaging during heart surgery can detect serious residual holes in the heart that may occur when surgeons repair a child’s heart defect, and offers surgeons the opportunity to close those holes during the same operation. Pediatric cardiology experts say using this tool, called transesophageal echocardiography (TEE), during surgery may improve outcomes for children with congenital heart disease.
Imagine conquering childhood cancer, only to find out that years down the road your heart may fail. Unfortunately, many children who have battled cancer face this reality. While often lifesaving, the effects of chemotherapy treatment (drugs that kill cancer cells) can take a toll on the developing body of a child, potentially resulting in life-threatening late side effects like cardiac damage.
A research team led by Robert Gerszten, MD, Chief of Cardiovascular Medicine at Beth Israel Deaconess Medical Center (BIDMC) and a Senior Associate Member of the Broad Institute, has received an award of more than $11 million as part of the Molecular Transducers of Physical Activity in Humans (MoTrPAC) consortium, a large-scale initiative of the National Institutes of Health (NIH) to investigate and map the molecular changes that occur in our bodies during and after exercise. This national research consortium seeks to advance our understanding of how physical activity improves and preserves health.
Scientists have enlisted the exotic properties of graphene to function like the film of an incredibly sensitive camera system in visually mapping tiny electric fields. They hope to enlist the new method to image electrical signaling networks in our hearts and brains.
Scientists from the McEwen Centre for Regenerative Medicine, University Health Network, have developed the first functional pacemaker cells from human stem cells, paving the way for alternate, biological pacemaker therapy.
A new minimally invasive technique for repairing the most common cardiac birth defect in extremely premature newborns can be performed safely with a high success rate in babies as small as 755 grams – about 1.6 pounds – only a few days after birth.
A genetic discovery by a team led by Dianna Milewicz, M.D., Ph.D., of The University of Texas Health Science Center at Houston (UTHealth) could help explain a cause of a mysterious artery-damaging disease that may affect up to an estimated 5 million Americans and often strikes without warning.