Feature Channels: Genetics

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Released: 3-Oct-2023 4:05 PM EDT
MSU finds genetic rescue is underused for endangered species recovery
Michigan State University

During a recent review of the U.S. Fish and Wildlife Service’s recovery plans for more than 200 endangered and threatened vertebrate species in the United States, Michigan State University researchers made an interesting discovery.

Newswise: Researchers Report Protein Mutation Creates ‘Super’ T Cells with Potential to Fight Off Cancer and Infections
Released: 3-Oct-2023 12:00 PM EDT
Researchers Report Protein Mutation Creates ‘Super’ T Cells with Potential to Fight Off Cancer and Infections
Johns Hopkins Medicine

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people’s own immune system T cells to fight cancer.

Newswise: Host genetics helps explain childhood cancer survivors’ mortality risk from second cancers
2-Oct-2023 4:00 PM EDT
Host genetics helps explain childhood cancer survivors’ mortality risk from second cancers
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital unraveled the genetics increasing the chance of survivors developing a second cancer later in life and its severity and prognosis to guide future cancer prevention.

Newswise: Exploring Genetic Changes in Aggressive Pancreatic Cancer
28-Sep-2023 8:05 AM EDT
Exploring Genetic Changes in Aggressive Pancreatic Cancer
Rutgers Cancer Institute of New Jersey

Investigators from Rutgers Cancer Institute of New Jersey and RWJBarnabas Health, the state’s leading cancer program and only National Cancer Institute-designated Comprehensive Cancer Center, investigated genomic alterations based on KRAS status to identify mutations in patients with KRAS wild type (WT).

Released: 2-Oct-2023 10:05 AM EDT
Multi-omics research on liver disease in Hispanics/Latinos funded through $4M NIH grant to UTHealth Houston
University of Texas Health Science Center at Houston

As one of just six sites in the country chosen for a new consortium of the National Institutes of Health (NIH), UTHealth Houston School of Public Health in Brownsville will use multi-omics in combination with environmental, epidemiologic, and clinical data, along with social determinants of health, to study non-alcoholic and non-viral liver disease in Hispanics/Latinos.

Newswise:Video Embedded sister-study-turns-20
VIDEO
Released: 2-Oct-2023 10:05 AM EDT
Sister Study turns 20
National Institute of Environmental Health Sciences (NIEHS)

To commemorate this 20-year milestone and to mark National Breast Cancer Awareness Month, NIEHS developed a suite of products including a 10-minute video available in English and available with Spanish captions, to showcase how the Sister Study started, what it has accomplished, and to spotlight the participants who make it all possible.

Newswise: New “DNA” podcast season explores how to harness change, ideas to improve business and medicine
Released: 2-Oct-2023 9:05 AM EDT
New “DNA” podcast season explores how to harness change, ideas to improve business and medicine
Vanderbilt University Medical Center

Vanderbilt University Medical Center’s (VUMC) award-winning original podcast series, “Vanderbilt Health DNA: Discoveries in Action” (DNA), returns to podcast feeds for Season 4 with conversations about how the future of tech, economic and cultural elements are shaping medicine, work and well-being. 

Newswise: Genome study reveals 30 years of Darwin’s finch evolution
Released: 2-Oct-2023 8:05 AM EDT
Genome study reveals 30 years of Darwin’s finch evolution
Uppsala University

An international team of researchers has released a landmark study on contemporary evolutionary change in natural populations. Their study uses one of the largest genomic datasets ever produced for animals in their natural environment, comprising nearly 4,000 Darwin’s finches.

Released: 2-Oct-2023 8:05 AM EDT
Explosion in fish biodiversity due to genetic recycling
Wellcome Trust Sanger Institute

Scientists show the extraordinary diversity of cichlid fish in Africa’s Lake Victoria was made possible by ‘genetic recycling’ - repeated cycles of new species appearing and rapidly adapting to different roles in the ecosystem.

Released: 1-Oct-2023 5:00 AM EDT
Largest-Ever Genetic Study of Suicide Finds New Risk Factors
University of Utah Health

The reasons why people attempt suicide are complex and include external triggers like trauma and stress, as well as inherited genetic factors. A new study has identified 12 DNA variants, or variations in the human genetic code, that are associated with risk of attempting suicide.

Released: 29-Sep-2023 11:00 AM EDT
Regel Therapeutics Awarded $1 Million from HS Chau Women in Enterprising Science Program at the Innovative Genomics Institute to Continue Developing Its Gene Modulation Technology
Regulus Therapeutics Inc.

Regel Therapeutics, a next generation gene therapy company utilizing proprietary technology to modulate gene expression, today announced that based upon the groundbreaking work of its Co-Founder and Chief Scientific Officer Dr. Navneet Matharu.

   
Newswise: Fish reveal cause of altered human facial development
Released: 29-Sep-2023 4:05 AM EDT
Fish reveal cause of altered human facial development
University of Tokyo

Some substances in medicines, household items and the environment are known to affect prenatal child development.

Released: 29-Sep-2023 4:05 AM EDT
Elk hoof disease likely causes systemic changes
Washington State University

Elk treponeme-associated hoof disease, previously thought to be limited to deformations in elks’ hooves, appears to create molecular changes throughout the animal’s system, according to epigenetic research from Washington State University.

Released: 28-Sep-2023 4:05 PM EDT
UC Irvine named one of CIRM’s cell and gene therapy manufacturing facilities
University of California, Irvine

Irvine, Calif., Sept. 28, 2023 — With a two-year, $2 million grant from the California Institute for Regenerative Medicine, the University of California, Irvine has earned membership in CIRM’s Cell and Gene Therapy Manufacturing Network.

Newswise: Noninvasive, ultrasound-based brain biopsy is feasible, safe in people
Released: 28-Sep-2023 1:05 PM EDT
Noninvasive, ultrasound-based brain biopsy is feasible, safe in people
Washington University in St. Louis

Researchers at Washington University in St. Louis have developed a technique called sonobiopsy that uses ultrasound and microbubbles to disrupt the blood-brain barrier temporarily and allow RNA, DNA and proteins from the brain to spill out into the blood, where they can be detected and analyzed.

Released: 28-Sep-2023 12:05 PM EDT
Researchers uncover why a gene mutant causes young children to have strokes
University of Texas Health Science Center at Houston

A discovery of a mutation in the gene ACTA2 has given researchers, led by Dianna Milewicz, MD, PhD, with UTHealth Houston, insight into understanding the cause of a rare and progressive problem with arteries in the brain and a cause of strokes in young children, called moyamoya disease.

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Newswise: Protein p53 regulates learning, memory, sociability in mice
22-Sep-2023 12:05 PM EDT
Protein p53 regulates learning, memory, sociability in mice
Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

Researchers at the Beckman Institute for Advanced Science and Technology have established the protein p53 as critical for regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice, illuminating the relationship between the protein-coding gene TP53 and neurodevelopmental and psychiatric disorders.

Released: 27-Sep-2023 5:05 PM EDT
Impact of genes linked to neurodevelopmental diseases found in Stanford Medicine-led study
Stanford Medicine

Stanford Medicine investigators and their colleagues sifted through a jumble of genes implicated in neurodevelopmental disorders and identified dozens of disparate troublemakers with similar effects.

Newswise: Researchers discover disease-causing stem cells in lungs of cystic fibrosis patients
Released: 27-Sep-2023 5:05 PM EDT
Researchers discover disease-causing stem cells in lungs of cystic fibrosis patients
University of Houston

Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

Released: 27-Sep-2023 1:05 PM EDT
Genetic variation with MASLD reveals subtypes and potential therapeutic avenues
Michigan Medicine - University of Michigan

A study reveals genetic subtypes, biomarkers, gene and pathway targets for the development of new treatments for this liver disease

Released: 27-Sep-2023 9:50 AM EDT
CHOP Researchers Improve Fitness of Cells Used in Cell Transplants
Children's Hospital of Philadelphia

A readily available, inexpensive small molecule drug can improve the fitness of hematopoietic stem and progenitor cells (HSPCs) that are modified outside of the body, potentially improving the success of procedures like ex vivo gene therapy, according to a new study by researchers at Children’s Hospital of Philadelphia (CHOP).

Released: 27-Sep-2023 8:05 AM EDT
Researchers combat Zika-associated fetal abnormalities using microRNA
Baylor College of Medicine

Before SARS-CoV-2 and the COVID-19 pandemic, there was the Zika virus epidemic, lasting from 2015 to 2016.

Newswise: Mount Sinai Announces New System Chief of Genomic Medicine
Released: 26-Sep-2023 1:05 PM EDT
Mount Sinai Announces New System Chief of Genomic Medicine
Mount Sinai Health System

Michael F. Murray, MD, Professor of Medicine at the Icahn School of Medicine at Mount Sinai, has been named the new System Chief of the Division of Genomic Medicine and the Clinical Director of the Institute for Genomic Health at Mount Sinai.

Newswise: Chromosomal instability in cancer cells causes DNA damage and promotes invasiveness
Released: 26-Sep-2023 4:00 AM EDT
Chromosomal instability in cancer cells causes DNA damage and promotes invasiveness
Fundació Institut de Recerca Biomèdica (IRB BARCELONA)

Chromosomal instability is a phenomenon characterised by rapid changes in the number and structure of chromosomes during cell division. It is very common in solid tumours and it is linked to the aggressive spread of cancer, that is to say, metastasis.

Released: 25-Sep-2023 3:05 PM EDT
Genetic code of rare kidney cancer cracked
Wellcome Trust Sanger Institute

The genetic code of a rare form of kidney cancer, called reninoma, has been studied for the first time.

Released: 25-Sep-2023 11:00 AM EDT
New Method Can Improve Assessing Genetic Risks For Non-White Populations
Johns Hopkins Bloomberg School of Public Health

A team led by researchers at Johns Hopkins Bloomberg School of Public Health and the National Cancer Institute has developed a new algorithm for genetic risk-scoring for major diseases across diverse ancestry populations that holds promise for reducing health care disparities.

Newswise: New findings on hair loss in men
Released: 22-Sep-2023 3:05 PM EDT
New findings on hair loss in men
Universitätsklinikum Bonn

A receding hairline, a total loss of hair from the crown, and ultimately, the classical horseshoe-shaped pattern of baldness.

Released: 22-Sep-2023 2:30 PM EDT
Same genes behind heart muscle disorders in humans and Dobermanns
University of Helsinki

Researchers have made a significant finding in determining the genetic background of dilated cardiomyopathy in Dobermanns. This research helps us understand the genetic risk factors related to fatal diseases of the heart muscle and the mechanisms underlying the disease, and offers new tools for their prevention.

Released: 21-Sep-2023 2:05 PM EDT
Researchers develop first method to study microRNA activity in single cells
Stockholm University

MicroRNAs are small molecules that regulate gene activity by binding to and destroying RNAs produced by the genes. More than 60% of all human genes are estimated to be regulated by microRNAs, therefore it is not surprising that these small molecules are involved in many biological processes including diseases such as cancer.

Newswise: Skipping counseling doesn't raise cancer gene test distress
Released: 21-Sep-2023 1:05 PM EDT
Skipping counseling doesn't raise cancer gene test distress
University of Washington School of Medicine and UW Medicine

“The accepted idea was that you needed genetic counseling before taking a genetic test,” said Dr. Elizabeth Swisher, a gynecologic oncologist at UW Medicine and professor of obstetrics and gynecology at the University of Washington School of Medicine. “But we’re finding out that many of these protocols actually represent barriers to testing.”

Released: 20-Sep-2023 12:05 PM EDT
New gene markers detect Lynch syndrome-associated colorectal cancer, Mayo Clinic study
Mayo Clinic

Researchers from Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine have discovered new genetic markers to identify Lynch syndrome-associated colorectal cancer with high accuracy.

Newswise: Case Western Reserve researchers identify inherited gene mutation linked to esophageal cancer
Released: 19-Sep-2023 8:05 AM EDT
Case Western Reserve researchers identify inherited gene mutation linked to esophageal cancer
Case Western Reserve University

Studying genes in families with a propensity for certain diseases has led to many critical advances in medicine, including the discovery of statins in family members who suffered heart attacks at an early age.

Released: 18-Sep-2023 1:05 PM EDT
Monell Center Team Discovers Markers that Can Predict How Children Will Tolerate Sweetened Medicine
Monell Chemical Senses Center

A multidisciplinary research group specializing in pediatrics, genetics, and psychophysics, co-led by the Monell Chemical Senses Center, has identified wide variation in the sensory perception of a pediatric formulation of ibuprofen — some that were tied to genetic ancestry, and some that were not.

Newswise: Devastating causes of childhood dementia revealed
Released: 18-Sep-2023 12:05 AM EDT
Devastating causes of childhood dementia revealed
University of Adelaide

It is a heartbreaking condition that robs children of their ability to walk, talk and recognise their loved ones and now the latest research has revealed the true impact of childhood dementia globally.

Released: 17-Sep-2023 3:05 PM EDT
Capacity building and knowledge transfer in genomics and bioinformatics
University of Konstanz

The African BioGenome Project, a large-scale international research project involving Konstanz bioinformatician Abdoallah Sharaf, successfully launched its “Open Institute”. The institute’s mission: accelerating knowledge exchange in biodiversity genomics and bioinformatics.

14-Sep-2023 8:05 AM EDT
Shared Genetic Factors Influence Risk for Both Disordered Eating and Alcohol Use in Late Adolescence
Research Society on Alcoholism

Certain genetic influences contribute to disordered eating and problematic alcohol use, leaving some people vulnerable to both conditions, according to a large study of late adolescent twins. Previous research has found concurrent eating disorders and risky drinking in younger teens amplify the chance of worse outcomes, including death.

     
Released: 15-Sep-2023 1:15 PM EDT
Scientists Take Next Big Step in Understanding Genetics of Schizophrenia
University of North Carolina School of Medicine

Scientists figuring out which of the 5,000-plus genetic variants associated with schizophrenia have an actual causal effect in the development of the condition. Some of genetic variants regulate or alter the expression of genes involved in the condition.

Newswise: Ohio State researchers publish national guidelines for ALS genetic testing, counseling
Released: 14-Sep-2023 1:05 PM EDT
Ohio State researchers publish national guidelines for ALS genetic testing, counseling
Ohio State University Wexner Medical Center

Researchers at The Ohio State University Wexner Medical Center and led the creation of evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.

Released: 13-Sep-2023 1:05 PM EDT
DNA breakthrough detects genetic diversity of invasive fish
Cornell University

Ecologists have demonstrated that the genetic material that species shed into their environments can reveal not only the presence of the species but also a broad range of information about the genetics of whole populations — information that can help scientists trace the source of a new invasive population as well as prevent further invasion.

Newswise: Researchers Release Results from Clinical Trial for Treatment of Primary Ciliary Dyskinesia
Released: 12-Sep-2023 10:05 AM EDT
Researchers Release Results from Clinical Trial for Treatment of Primary Ciliary Dyskinesia
University of North Carolina School of Medicine

A phase 2 study, led by Thomas W. Ferkol, MD, at the UNC School of Medicine, demonstrates safety and efficacy of idrevloride with hypertonic saline for treatment of primary ciliary dyskinesia, a rare genetic disorder that can lead to permanent lung damage.

Newswise: Researchers Create a New Window on Leading Genetic Cause of Alzheimer’s
Released: 12-Sep-2023 10:00 AM EDT
Researchers Create a New Window on Leading Genetic Cause of Alzheimer’s
Pacific Northwest National Laboratory

Scientists have opened a new view into the workings of the brain and central nervous system, detecting a diverse set of important molecules known as lipoproteins. The most common protein on the particles is apolipoprotein E; one form of APOE puts people at higher risk of Alzheimer’s disease.

Released: 11-Sep-2023 12:05 PM EDT
Electronic detection of DNA nanoballs enables simple pathogen detection
Karolinska Institute

Researchers at Karolinska Institute have developed a novel method using DNA Nanoballs to detect pathogens, aiming to simplify nucleic acid testing and revolutionize pathogen detection.

Newswise: Study links epigenetic changes to historic trauma in Alaska Native communities
Released: 8-Sep-2023 11:05 AM EDT
Study links epigenetic changes to historic trauma in Alaska Native communities
College of Liberal Arts and Sciences, University of Illinois Urbana-Champaign

Researchers investigated the relationship between historical trauma experienced by Alaska Native communities and epigenetic markers on genes that previous studies have linked to trauma.

   
Newswise: Study illuminates mechanism that annotates genetic information passed from fathers to offspring
6-Sep-2023 2:30 PM EDT
Study illuminates mechanism that annotates genetic information passed from fathers to offspring
Van Andel Institute

Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.

Released: 5-Sep-2023 12:15 PM EDT
Study confirms it: Opposites don't actually attract
University of Colorado Boulder

Opposites don’t actually attract. That’s the takeaway from a sweeping CU Boulder analysis of more than 130 traits and including millions of couples over more than a century.

Newswise: Linguistics may help to understand some “strangenesses” of the genetic code
Released: 5-Sep-2023 7:05 AM EDT
Linguistics may help to understand some “strangenesses” of the genetic code
Scientific Project Lomonosov

The linguist have developed the comparison of the genetic code with language where nucleotides act as letters, and introduced the concept of “a semiotic nucleotide” – the minimal element which makes it possible distinguishing between codons – coding units of DNA.

   
Released: 4-Sep-2023 8:40 AM EDT
Largest genetic study of epilepsy to date provides new insights on why epilepsy develops and potential treatments
International League Against Epilepsy

The largest genetic study of its kind, coordinated by the International League Against Epilepsy (ILAE), has discovered specific changes in our DNA that increase the risk of developing epilepsy.

Released: 31-Aug-2023 4:05 PM EDT
Advanced technology reveals intricate details of zinc transportation in cells
Tohoku University

A group of researchers has unearthed the secrets behind a tiny but crucial protein that shuttles zinc ions (Zn2+) within our bodies. The discovery offers a deeper understanding of how our cells maintain optimal health.



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