Sabrina L. Spencer, PhD, is a CU Boulder researcher and CU Cancer Center member. Spencer recently won the Damon Runyon-Rachleff Innovation Award and the Emerging Leader Award. She will use the grants to continue her research on drug resistance in cancer cells.
Dawn Elliott, Blue and Gold Distinguished Professor of Biomedical Engineering at the University of Delaware, has won an $11.8 million grant from the National Institutes of Health to establish the Delaware Center for Musculoskeletal Research -- an NIH-designated Center of Biomedical Research Excellence (COBRE). From tendonitis to osteoarthritis, the center will focus on uncovering what happens at the cellular level when injuries and inflammation occur and will test potential therapeutic interventions.
One of the keys to having a healthy brain at any age is having a healthy blood-brain barrier, a complex interface of blood vessels that run through the brain. Research shows the blood-brain barrier leaks as we age, and we lose cells called pericytes. But could this leak and the difficulties in recall be the early stages of Alzheimer’s disease?
The U.S. Department of Energy (DOE) today announced up to $30 million to support scientific research that will ensure American businesses can reliably tap into a domestic supply of critical elements and minerals, such as lithium, cobalt and nickel, needed to produce clean energy technologies.
Anne Berg, PhD, Research Professor, and Sandi Lam, MD, MBA, Chief of Neurosurgery at Ann & Robert H. Lurie Children’s Hospital of Chicago have been approved for a $4 million funding award by the Patient-Centered Outcomes Research Institute (PCORI) to conduct a study, Comparative effectiveness of palliative surgery versus additional anti-seizure medications for Lennox-Gastaut Syndrome.
Researcher at Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School has received $400,000 in awards to help identify and overcome multi-level factors such as patient, health professionals and clinic systems affecting optimal use of colorectal cancer preventative screening options for patients with elevated medical and social risks throughout the United States.
DALLAS – March 17, 2021 – UT Southwestern researchers have identified the structure of a key member of a family of proteins called nicotinic acetylcholine receptors in three different shapes. The work, published online today in Cell, could eventually lead to new pharmaceutical treatments for a large range of diseases or infections including schizophrenia, lung cancer, and even COVID-19.
The UND School of Medicine & Health Sciences (SMHS) has received a five-year award from the National Institutes of Health totaling more than $10 million to develop an Indigenous Trauma & Resilience Research Center. According to Dr. Don Warne, director of the School’s Indians Into Medicine (INMED) and public health programs, the goal of the research center will be to address the impact of historical and unresolved trauma on health inequities within the American Indian and Alaska Native population.
Scientists at Sanford Burnham Prebys Medical Discovery Institute demonstrated for the first time that blocking “cell drinking,” or macropinocytosis, in the thick tissue surrounding a pancreatic tumor slowed tumor growth—providing more evidence that macropinocytosis is a driver of pancreatic cancer growth and is an important therapeutic target. The study was published in Cancer Discovery, a journal of the American Association for Cancer Research.
Researchers at Penn Medicine used machine learning-aided analysis to uncover top positive and negative themes in patient Yelp reviews of substance use treatment facilities
Researchers at Rutgers School of Dental Medicine have found evidence that two types of mouthwash disrupt the COVID-19 virus under laboratory conditions, halting its ability to replicate in a human cell.
After a traumatic injury, returning to work (RTW) can be a strong indication of healing and rehabilitation and may play a pivotal role in promoting physical and functional recovery. But how does RTW after a traumatic injury affect mental health recovery, particularly in individuals who experience social and economic marginalization?
USAble Life is giving back to the community by donating $50,000 to create an endowed scholarship for first-generation business students at the University of Arkansas at Little Rock.
As the planet heats up, are lakes releasing more carbon dioxide into the atmosphere? With a prestigious National Science Foundation Faculty Early Career Development (CAREER) grant, researcher Kevin Rose will examine large-scale patterns in concentrations of carbon dioxide (CO2) and dissolved oxygen to answer the question.
The Pennsylvania Pediatric Medical Device Consortium (PPDC) has announced its latest round of seed grants to companies developing medical devices for children. The Consortium chose five projects from nine finalists in a competition to receive seed grants of $50,000 each.
The coronavirus pandemic has led to several temporary regulatory relaxations and policy innovations in treatment for opioid use disorder aimed at making it easier for those seeking care to access treatment without risking in-person interactions. The Foundation for Opioid Response Efforts (FORE) today announced it is providing grants totaling $1.3 million to six organizations to assess the impact of these temporary measures and inform future policies to improve access and promote equity for the treatment of opioid use disorder.
A Nature study shows that the leprosy drug clofazimine, which is FDA approved and on the World Health Organization’s List of Essential Medicines, exhibits potent antiviral activities against SARS-CoV-2 and prevents the exaggerated inflammatory response associated with severe COVID-19. Based on these findings, a Phase 2 study evaluating clofazimine as an at-home treatment for COVID-19 could begin immediately.
A new $1.5 million grant awarded to faculty at Binghamton University, State University of New York could help improve makerspace learning for youths and help them find support during moments of failure.
DHS S&T awarded $775,000 to the Harvard University T.H. Chan School of Public Health to conduct research and evaluate the impact of the Department’s Blue Campaign.
UC Davis Health researchers studying executive control in adolescents and young adults with autism have published new research that suggests a unique approach, rather than impairment.
Engineers created light-activated materials that execute precise movements and form complex shapes without the need for wires, motors or other energy sources. The research could lead to smart light-driven systems such as high-efficiency solar cells that automatically follow the sun’s direction.
New research by the National Institutes of Health found that unbalanced progesterone signals may cause some pregnant women to experience preterm labor or prolonged labor. The study in mice — published online in the Proceedings of the National Academy of Sciences — provides novel insights for developing treatments.
A foodborne fungus that is harmless to most people exacerbates gastrointestinal symptoms in people with Crohn’s disease by preventing intestinal ulcers from healing, according to a new study from Washington University School of Medicine in St. Louis and the Cleveland Clinic. The findings suggest that antifungal medications or dietary interventions may help alleviate the symptoms of Crohn’s.
The highest-energy cosmic rays come from subatomic interactions within star clusters, not supernovae, say Michigan Tech physicists and collaborators. For decades, researchers assumed cosmic rays are flung into space from supernova. But new research suggests even supernovae are not strong enough to push particles to petaelectronvolts (PeVs). Instead, the researchers posit that star clusters like the Cygnus Cocoon serve as PeVatrons capable of moving particles at such high energy rates.
In two new studies published today in Cancer Cell, researchers from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard used the emerging technology of single-cell RNA sequencing to draw a clearer picture of how kidney tumors’ microenvironments change in response to immunotherapy. The researchers believe that this work points to potential targets for new drug therapies.
A gene therapy for chronic pain could offer a safer, non-addictive alternative to opioids. Researchers at the University of California San Diego developed the new therapy, which works by temporarily repressing a gene involved in sensing pain. It increased pain tolerance in mice, lowered their sensitivity to pain and provided months of pain relief without causing numbness.
DHS S&T announces today the recipients of Scientific Leadership Awards who will partner with S&T-supported COE to develop Homeland Security (HS) course content and creatively engage students and faculty in research relevant to the complex challenges faced by DHS and the Homeland Security Enterprise.
The mosquito protein AEG12 strongly inhibits the family of viruses that cause yellow fever, dengue, West Nile, and Zika and weakly inhibits coronaviruses, according to scientists at the National Institutes of Health and their collaborators. They found that AEG12 works by destabilizing the viral envelope, breaking its protective covering.
UT Southwestern scientists have identified key genes involved in brain waves that are pivotal for encoding memories. The findings, published online this week in Nature Neuroscience, could eventually be used to develop novel therapies for people with memory loss disorders such as Alzheimer’s disease and other forms of dementia.
Researchers at the University of Alabama at Birmingham have identified a new molecular target that could potentially treat the deadly, aging-related lung disease idiopathic pulmonary fibrosis (IPF). The study, which will be published March 10 in the Journal of Experimental Medicine (JEM), suggests that targeting a protein called MDM4 could prevent respiratory failure by initiating a genetic program that removes scar tissue from the lungs.
Dr. Matthew Mimiaga, director of the UCLA Center for LGBTQ Advocacy, Research & Health (C-LARAH), leads $8.8 million project HIV prevention project funded by the National Institutes of Health
Expectant women are more likely to give birth early if they have high blood levels of a chemical used in flame retardants compared with those who have limited exposure, a new study finds.
The Glaucoma Foundation (TGF) and Research to Prevent Blindness (RPB) have partnered to launch a new grant aimed at supporting under-represented racial and ethnic minority researchers in the pursuit of glaucoma research. The TGF (sponsored by Patricia Hill) / RPB Fellowships in Glaucoma provide one-year, $10,000 fellowships focused on substantive glaucoma research.
The U.S. Department of Energy (DOE) today announced plans to provide $30 million for Quantum Information Science (QIS) research that helps scientists understand how nature works on an extremely small scale—100,000 times smaller than the diameter of a human hair. QIS can help our nation solve some of the most pressing and complex challenges of the 21st century, from climate change to national security.
A new study from the University of California, Irvine shows that compounds in both green and black tea relax blood vessels by activating ion channel proteins in the blood vessel wall. The discovery helps explain the antihypertensive properties of tea and could lead to the design of new blood pressure-lowering medications.
In a new study from the U.S. Department of Energy’s Argonne National Laboratory, researchers have demonstrated a new material that has an excellent balance of parameters needed to generate a good accelerator beam.
Researchers will be dedicated to battling hearing loss resulting from numerous causes. They will tackle hearing loss in children whose hearing is compromised by antibiotics or other medical treatments, to persons suffering hearing loss in the wake of cancer therapies, those who suffer deafness due to such infections as meningitis, through to natural hearing loss caused by aging.
Using genetic engineering, researchers at UT Southwestern and Indiana University have reprogrammed scar-forming cells in mouse spinal cords to create new nerve cells, spurring recovery after spinal cord injury. The findings, published online today in Cell Stem Cell, could offer hope for the hundreds of thousands of people worldwide who suffer a spinal cord injury each year.
Equitable implementation of COVID‐19 vaccine delivery is a national and global priority, with a strong focus on reducing existing disparities and not creating new disparities. But while a framework has been recognized for equitable allocation of COVID‐19 vaccine that acknowledges the rights and interests of sexual and gender minorities (SGM), it fails to identify strategies or data to achieve that goal.
Harvard researchers reconstructed the evolutionary history of a mutation that gave rise to cancer decades later in two patients. In a 63-year-old patient, it occurred at around age 19; in a 34-year-old patient, at around age 9.
New research from Washington University School of Medicine in St. Louis has found that new variants of the virus that causes COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic, potentially undermining the effectiveness of vaccines and antibody-based drugs now being used to prevent or treat COVID-19.
A team of Roswell Park Comprehensive Cancer Center researchers has identified a new biomarker that could predict response to immune checkpoint inhibitors (ICI) shortly after patients with non-small cell lung cancer (NSCLC) initiate therapy. This discovery, published today in the journal Nature Communications, is not only an important step forward in lung cancer treatment, but also has implications for other malignancies, according to lead author Fumito Ito, MD, PhD, FACS.
DHS S&T AWARDS $153K in phase 1 funding to small business for maritime object tracking technology.
At the beginning of an immune response, a molecule known to mobilize immune cells into the bloodstream, where they home in on infection sites, rapidly shifts position, a new study shows. Researchers say this indirectly amplifies the attack on foreign microbes or the body’s own tissues.
The Moore Center for the Prevention of Child Sexual Abuse at the Johns Hopkins Bloomberg School of Public Health has been awarded $10.3 million from Oak Foundation for the Center’s new “Global Perpetration Prevention: Translating Knowledge into Action” program.
Women who experience an accelerated accumulation of abdominal fat during menopause are at greater risk of heart disease, even if their weight stays steady, according to a University of Pittsburgh Graduate School of Public Health-led analysis published today in the journal Menopause.
According to the World Health Organization, one in six worldwide deaths are attributed to cancer, but not due to initial malignant tumors. They were caused by the spread of cancer cells to surrounding tissues, which consist largely of collagen. That was the focus of a recent study by Stanford University and Purdue University researchers.
Connected, automated vehicles promise to save energy and improve safety. Michigan Tech engineers propose a modeling framework for cooperative driving. Simulation results show that the cooperative automated eco-driving algorithm saves energy — 7% under light traffic and 23% under heavy traffic.
Researchers at the University of California San Diego School of Medicine and Massachusetts General Hospital have identified a new drug that could prevent Alzheimer’s disease by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques in the brain. The study, which will be published March 2 in the Journal of Experimental Medicine (JEM), demonstrates that the drug is safe and effective in rodents and monkeys, paving the way for future clinical trials in humans.
A team of researchers co-led by Michael Frohman, MD, PhD, of Stony Brook University, has identified an important cause of congenital heart disease. They discovered that certain loss of functions in the PLD1 (Phospholipase D1) gene causes congenital right-sided cardiac valve defects and neonatal cardiomyopathy.
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