People who suffer from a rare illness, the Mal de Debarquement Syndrome (MdDS), now have a chance for full recovery thanks to treatment developed by researchers at the Icahn School of Medicine at Mount Sinai.
Today the journal Science published results of a preclinical study demonstrating that treatment with orally available RNA splicing modifiers of the SMN2 gene starting early after birth is preventing deficits in a mouse model of Spinal Muscular Atrophy (SMA).
Building upon previous research, scientists at the University of California, San Diego School of Medicine and Veteran’s Affairs San Diego Healthcare System report that neurons derived from human induced pluripotent stem cells (iPSC) and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons extending virtually the entire length of the animals’ central nervous system.
At least one part of the human brain may be able to process information the same way in older age as it does in the prime of life, according to new research conducted at the University of Adelaide.
Lab mice have traits not found in wild mice, such as caring for others’ pups. Dr. Tali Kimchi, who studies the basis of social behavior – including maternal instinct – needed lab mice with those wild traits. She developed a mouse model that let her explore, for the first time, the biological roots of aggressiveness in females, particularly toward pups.
UC San Francisco researchers have identified cells’ unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large-scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.
Our brains are able to judge the trustworthiness of a face even when we cannot consciously see it, a team of scientists has found. Their findings shed new light on how we form snap judgments of others.
Researchers have identified genetic variants that are associated with severe adverse skin reactions to the antiepileptic drug phenytoin, according to a study in the August 6 issue of JAMA.
Scientists hope to borrow strategy from simpler animals to repair damaged spinal cord nerves in humans.
Children and fetuses are the most at risk from neurological and biological damage that results from microwave radiation emitted by wireless devices, due to the higher rate of absorption of microwave radiation by children than by adults.
In the first study of its kind, Prapti Gautam, PhD, and colleagues from The Saban Research Institute of Children’s Hospital Los Angeles found that children with fetal alcohol spectrum disorders (FASD) showed weaker brain activation during specific cognitive tasks than their unaffected counterparts.
Research led by the University of Adelaide has resulted in new insights into clinical depression that demonstrate there cannot be a "one-size-fits-all" approach to treating the disease.
A new brain imaging study has identified the mechanisms involved in balancing blameworthiness and the emotion-driven urge to punish.
Salk scientists find that a plant used for centuries by healers of São Tomé e Príncipe holds lessons for modern medicine.
New research at Washington University School of Medicine in St. Louis helps explain why brain tumors occur more often in males and frequently are more harmful.
This supplement to the Journal of Neurosurgery covers the current knowledge of anticoagulant-associated intracerebral hemorrhage (AAICH) and methods in use for management of the condition. CME credits are available.
Athletes and others reporting cognitive difficulties after a head injury are usually diagnosed as having had a concussion. But is it really a concussion? A new study published by University at Buffalo medical faculty finds that many of the same symptoms are common to concussions and to injuries to the neck and/or balance system, known collectively as cervical/vestibular injuries.
Researchers at Johns Hopkins have mapped the sound-processing part of the mouse brain in a way that keeps both the proverbial forest and the trees in view. Their imaging technique allows zooming in and out on views of brain activity within mice, and it enabled the team to watch brain cells light up as mice “called” to each other. The results, which represent a step toward better understanding how our own brains process language, appear online July 31 the journal Neuron.
Researchers at the University of California, San Diego School of Medicine have evidence suggesting that neurons in the developing brains of mice are guided by a simple but elegant birth order rule that allows them to find and form their proper connections.
Controlled application of vacuum pressure is a promising approach to limiting tissue damage after traumatic brain injury (TBI), suggests an experimental study in the August issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
A new study gives insight into the relationship between depression and dementia. The study is published in the July 30, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A new study by neuropsychiatric researchers at Rush University Medical Center gives insight into the relationship between depression and dementia.
Researchers at UC San Francisco have found that children with sensory processing disorders have decreased structural brain connections in specific sensory regions different than those in autism, further establishing SPD as a clinically important neurodevelopmental disorder.
In response to the Institute of Medicine's report on the current graduate medical education system, "Graduate Medical Education That Meets the Nation’s Health Needs," the American Association of Neurological Surgeons and Congress of Neurological Surgeons present concerns regarding the looming shortage of neurosurgeons in the United States.
Parkinson's disease (PD) patients may confront a common but largely unrecognized challenge: the occurrence of impulse control disorders (ICDs) such as compulsive gambling, sexual behavior, eating, or spending. A team of investigators from the Perelman School of Medicine at the University of Pennsylvania and the Parkinson's Disease Research, Education and Clinical Center (PADRECC) at the Philadelphia Veterans Affairs Medical Center conducted a pilot study and found that the opioid antagonist naltrexone may be an effective treatment for diminishing ICD symptoms in PD patients. The results were published in the journal Neurology.
People who have the most common genetic mutation linked to obesity respond differently to pictures of appetizing foods than overweight or obese people who do not have the genetic mutation, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
A research team led by Raymond Tak Fai Cheung, PhD and student Lynn Yan-Hua Sang, PhD of the University of Hong Kong suggests a new therapeutic strategy for intracerebral hemorrhage: injecting self-assembling peptide nanofiber scaffolds (SAPNS) directly into a hemorrhagic lesion.
Researchers at the UNC School of Medicine have found that the protein glycogen synthase kinase-3, or GSK-3, is crucial for proper brain development early in life.
Sandia National Laboratories is working with Arizona State University on the challenge of recording and measuring signals from the brain.
By analyzing the brainwaves of 16 individuals as they watched mainstream television content, researchers were able to accurately predict the preferences of large TV audiences, up to 90 percent in the case of Super Bowl commercials
There's some good news for parents of preterm babies – latest research from the University of Adelaide shows that by the time they become teenagers, the brains of many preterm children can perform almost as well as those born at term.
Salk scientists show that the little-known supportive cells are vital in cognitive function.
New technologies for monitoring brain activity are generating unprecedented quantities of information. That data may hold new insights into how the brain works – but only if researchers can interpret it. To help make sense of the data, neuroscientists can now harness the power of distributed computing with Thunder, a library of tools developed at the Howard Hughes Medical Institute's Janelia Research Campus. Thunder speeds the analysis of data sets that are so large and complex they would take days or weeks to analyze on a single workstation – if a single workstation could do it at all. Janelia group leaders Jeremy Freeman, Misha Ahrens, and other colleagues at Janelia and the University of California, Berkeley, report in the July 27, 2014, issue of the journal Nature Methods that they have used Thunder to quickly find patterns in high-resolution images collected from the brains of active zebrafish and mice with multiple imaging techniques.
Researchers at UT Southwestern Medical Center have identified neural pathways that increase understanding of how the brain regulates body weight, energy expenditure, and blood glucose levels – a discovery that can lead to new therapies for treating Type 2 diabetes and obesity
A study involving nearly 27,000 older adults on five continents found that nearly 1 in 10 met criteria for pre-dementia based on a simple test that measures how fast people walk and whether they have cognitive complaints. People who tested positive for pre-dementia were twice as likely as others to develop dementia within 12 years. The study, led by scientists at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center, was published online on July 16, 2014 in Neurology®, the medical journal of the American Academy of Neurology.
Researchers at the Stowers Institute for Medical Research, have identified the functions of two classes of pheromone receptors, and found pheromones crucial to triggering the mating process in mice.
Today, nearly 700,000 people in the U.S. are living with a brain tumor, and yet, when it comes to pinpointing causes or risk factors, scientists are still searching for answers.
Researchers at UC San Francisco (UCSF) have discovered that endostatin, a protein that once aroused intense interest as a possible cancer treatment, plays a key role in the stable functioning of the nervous system.
New research suggests that regularly monitoring your pulse after a stroke or the pulse of a loved one who has experienced a stroke may be a simple and effective first step in detecting irregular heartbeat, a major cause of having a second stroke. The study is published in the July 23, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A team from ASU and UC Irvine has discovered a key component to better understanding how traumatic memories may be strengthened in women. Their study's findings suggest that developing clinical treatments that could lower norepinephrine levels immediately following a traumatic event might offer a way to prevent this memory-enhancing mechanism from occurring.
A new University of Iowa study, published online July 14 in the Proceedings of the National Academy of Sciences, reveals a potential link between epilepsy and neurodegenerative disorders.
Autoimmune disorders may share certain pathogenic mechanisms with cancer, according to a new report published in PLOS ONE by Linda Kusner, Ph.D., assistant research professor in the Department of Pharmacology and Physiology at the George Washington University School of Medicine and Health Sciences.
Researchers may be one step closer to better understanding how anesthesia works. A study in the August issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists® (ASA®), found stimulating a major dopamine-producing region in the brain, the ventral tegmental area (VTA), caused rats to wake from general anesthesia, suggesting that this region plays a key role in restoring consciousness after general anesthesia. Activating this region at the end of surgery could provide a novel approach to proactively induce consciousness from anesthesia in surgical patients, researchers say.
Unclogging the body’s protein disposal system may improve memory in patients with Alzheimer’s disease, according to researchers in Korea.
New research provides an intriguing glimpse into the processes that establish connections between nerve cells in the brain. These connections, or synapses, allow nerve cells to transmit and process information involved in thinking and moving the body.
Two researchers from the University of Kentucky have demonstrated a connection between sensitivity to light or noise and increased emotional symptoms in teens who have suffered a concussion.
The mysterious condition once known as “water on the brain” became less murky, thanks to a research group led in part by a Case Western Reserve researcher. The study illustrates how one genetic error can contribute to hydrocephalus. The findings appear online July 17 in the journal Neuron.
A study published today found that almost 40 per cent of Ontario female prisoners have a history of traumatic brain injury (TBI). Unlike the men participating in the study, half of these women sustained a TBI before committing their first crime.
By carefully watching nearly a hundred hours of video showing mother rats protecting, warming, and feeding their young pups, and then matching up what they saw to real-time electrical readings from the pups’ brains, researchers at NYU Langone Medical Center have found that the mother’s presence and social interactions — her nurturing role — directly molds the early neural activity and growth of her offsprings’ brain.
Even mild traumatic brain injury may cause brain damage and thinking and memory problems, according to a study published in the July 16, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.
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