Children’s Hospital Los Angeles has performed its 500th liver transplant—a milestone achievement that only a handful of pediatric centers in the country have reached.
Findings from a pioneering study in The American Journal of Pathology, published by Elsevier, reveal that administration of the neuropeptide α-melanocyte–stimulating hormone (α-MSH) promotes corneal healing and restores normal eye function to an otherwise degenerating and diseased cornea by providing protection against cell death and promoting cell regeneration.
The Endocrine Society, the world’s oldest and largest professional medical society devoted to the study and treatment of hormone-related conditions, applauds Governor Mike Dewine’s veto of a proposed Ohio law that would have banned gender-affirming care for minors.
Cedars-Sinai Cancer investigators have discovered a new way to predict whether a cancer of the immune system will recur in patients treated with a bone marrow transplant.
With the rise in machine learning applications and artificial intelligence, it's no wonder that more and more scientists and researchers are turning to supercomputers. Supercomputers are commonly used for making predictions with advanced modeling and simulations. This can be applied to climate research, weather forecasting, genomic sequencing, space exploration, aviation engineering and more.
A microbial sensor that helps identify and fight bacterial infections also plays a key role in the embryonic development of blood stem cells, valuable new insight in the effort to create patient-derived blood stem cells that could eliminate the need for bone marrow transplants.
Hackensack Meridian Hackensack University Medical Center is now part of an elite group of hospitals in the U.S. to have performed more than 300 kidney transplants in one year.
UChicago Medicine Comer Children’s Hospital will be among the first in the country to offer gene therapy for sickle cell disease after regulators approved two new treatments.
New research from Cedars-Sinai’s Comprehensive Transplant Center found that a monoclonal antibody treatment reduced the risk of COVID-19 in a large group of solid organ transplant patients who were administered the drug as a preventive measure against the disease.
With virus cases rising and the holidays nigh, three expert from University of Michigan Health give their top 12 tips for avoiding or reducing the impact of COVID-19, flu, RSV, pneumonia and whooping cough in adults and kids.
Credentialed press representatives are invited to attend The Society of Thoracic Surgeons’ 60th Annual Meeting, featuring late-breaking scientific research, thought-provoking lectures, cutting-edge technologies, and innovative cardiothoracic surgery products.
A national, multicenter clinical trial (BMT CTN 1507) of low-dose haploidentical (half-matched) bone marrow transplant to treat severe sickle cell disease found the treatment to be safe and curative for adults with serious sickle cell-related health complications.
For thousands of people around the world waiting for a kidney, paired exchange serves as a beacon of hope. One person's willingness to undergo the act of Kidney Paired Donation (KPD) often sets in motion a chain of beautiful and selfless acts, where individuals give and receive the chance for a better life.
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It's the moooost wonderful time...of the year! Are you looking for new story ideas that are focused on the winter holiday season? Perhaps you're working on a story on on managing stress and anxiety? Perhaps you're working on a story on seasonal affective disorder? Or perhaps your editor asked you to write a story on tracking Santa? Look no further. Check out the Winter Holidays channel.
A collaboration between researchers from Cornell and University of Alberta, Edmonton, has created a new technique to treat Type 1 diabetes: implanting a device inside a pocket under the skin that can secrete insulin while avoiding the immunosuppression that typically stymies management of the disease.
Three physician-scientists who have relocated to Buffalo, New York, to join Roswell Park Comprehensive Cancer Center will apply highly specialized transplantation and cell therapy (TCT) expertise to both patient care and the development of New York State’s first cell therapy manufacturing and research hub. Brian Betts, MD, has joined Roswell Park as Vice Chair of Strategic Initiatives within the Transplant & Cellular Therapy Section, Department of Medicine; Kanwaldeep Mallhi, MD, was named Associate Professor of Oncology and Clinical Director of Pediatric Transplantation and Cellular Therapy in the Department of Pediatrics; and Shernan Holtan, MD, will join the Roswell Park faculty in February as Chief of Blood and Marrow Transplant in the Department of Medicine.
This holiday season, Valance Sams, Sr. hopes to finish the most important thank-you note he’s ever written—one he’s been pondering for months. It’s been challenging to get all that he wants to say down on paper, in just the right way. Most days, a flood of emotions gets in his way.
The investigational procedure, done in collaboration with University of Pittsburgh Medical Center (UPMC), harvests testicular tissue containing stem cells in prepubertal boys who are about to undergo treatments for cancer or other conditions that might result in infertility.
A study from Washington University School of Medicine in St. Louis and Mid-America Transplant showed that the long-standing practice of treating deceased organ donors with thyroid hormone does not help preserve heart function, may cause harm and should be discontinued.
Memorial Sloan Kettering Cancer Center (MSK) and NMDP/Be The Match® today announced the launch of the “American Symphony: Become a Lifesaver” campaign to increase registration of blood stem cell and marrow donors to the national registry and improve access to blood stem cell transplants.
Namrata G. Jain, MD, medical director of Pediatric Kidney Transplant at Joseph M. Sanzari Children’s Hospital at Hackensack University Medical Center, and associate professor of Pediatrics at Hackensack Meridian School of Medicine, has been appointed co-chair of the Transplant Working Group of the prestigious Pediatric Nephrology Research Consortium (PNRC).
Despite a record year for organ donation last year in the U.S., an estimated 17 people die every day waiting for a transplant. Yet Mayo Clinic transplant experts are optimistic that solutions to some of the biggest transplant challenges are on the horizon, thanks to new technology, research and innovations.
JDRF, the world’s largest nonprofit supporter of Type 1 diabetes research, has awarded a $750,000 grant to a team of Michigan State University researchers.
Patients in end-of-life care settings are rarely asked about eye donation despite positive views towards it. Healthcare professionals need training to discuss eye donation with patients.
Researchers in Sweden have developed a microscale device for implantation in the eye, which presents new opportunities for cell-based treatment of diabetes and other diseases
Using zebrafish as a model, investigators have determined a suitable combination of chemical compounds in which to store hearts, and potentially other organs, when frozen for extended periods of time before transplantation.
CLEVELAND: A team from Cleveland Clinic has developed a new model for prioritizing patients waiting for a lung transplant, aimed at improving outcomes and reducing deaths among those in need of donor lungs. The new method offers an improved strategy for organ allocation by taking into account how the time a patient has spent on the waiting list could impact the severity of their disease and the urgency of their need for a transplant.
The results of a study looking at this new method were published today in The American Journal of Respiratory and Critical Care Medicine.
A readily available, inexpensive small molecule drug can improve the fitness of hematopoietic stem and progenitor cells (HSPCs) that are modified outside of the body, potentially improving the success of procedures like ex vivo gene therapy, according to a new study by researchers at Children’s Hospital of Philadelphia (CHOP).
When an immunocompromised person’s system begins to recover and produce more white blood cells, it’s usually a good thing – unless they develop a potentially deadly inflammatory condition.
FINDINGS People from socioeconomically distressed communities who underwent heart transplantation between 2004 and 2018 faced a 10% greater relative risk of experiencing graft failure and dying within five years compared to people from non-distressed communities. In addition, following implementation of the 2018 UNOS Heart Allocation policy, transplant recipients between 2018 and 2022 faced an approximately 20% increase in relative risk of dying or experiencing graft failure within three years compared with the pre-policy period.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Recent developments include a novel computational tool to detect single base pair DNA changes in single-cell sequencing data, a potential target to treat hypertension caused by drugs commonly used in organ transplants, further insights into the steps involved in genetic recombination, a novel treatment target for a subset of adenoid cystic carcinoma (ACC), a combination therapy that improves outcomes in certain patients with acute myeloid leukemia (AML), and a target for treating prolonged cytopenia in patients with relapsed/refractory large B cell lymphoma treated with chimeric antigen receptor (CAR) T cell therapy.
A multi-site, five-year study led by a MedStar Heart & Vascular Institute cardiologist and fellow researchers from across the country have demonstrated the benefits of routine genetic testing for patients with advanced disease from dilated cardiomyopathy (DCM), a disease of the heart muscle and their at-risk family members.
In a breakthrough in liver transplantation that may lead to the ability to connect more living donors and patients, a new matching system designed by a team led by Boston College economists enabled the world’s first four-way liver exchange and a cascade of additional matches.
Cultivated autologous limbal epithelial cells (CALEC) transplant, in which stem cells from the healthy eye and transplanted into the injured eye, for significant cornea injuries was found safe and led to gains in preliminary phase I clinical trial.
A two-year study found that spikes of post-vaccination SARS-CoV-2 viral infections (commonly known as COVID-19 breakthrough cases) remain common, yet hospitalization rates have dramatically dropped following the first wave of the virus’ omicron subvariant.
Rutgers Cancer Institute of New Jersey and RWJBarnabas Health have appointed Niketa C. Shah, MD, as chief of Pediatric Bone Marrow Transplantation and Cellular Therapies at New Jersey’s leading cancer program.
Bridge to Life Ltd. (BTL), a leading global supplier of organ preservation and perfusion technologies, announced today its divestiture of certain assets to TransMedics, Inc., a wholly owned subsidiary of TransMedics Group, Inc. (NASDAQ: TMDX), including its EVOSS heart and lung and LifeCradle heart perfusion assets.
New research shows how using molecular tools and alternative gene splicing can make a protein called CEACAM1 more protective against liver injury during transplantation, thus reducing organ injury and ultimately improving post-transplant outcomes.
Below are summaries of recent Fred Hutchinson Cancer Center research findings and other news. Reporting on wildfire smoke? Fred Hutch clinicians and researchers are available to their expertise. Dr. Trang VoPham is an epidemiologist focusing on environmental exposures and risk, follow her on social media.