A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.
Researchers at the Icahn School of Medicine at Mount Sinai and others have identified a neurodevelopmental disorder, caused by mutations in a single gene, that affects tens of thousands of people worldwide. The work, published in the May 31 online issue of Nature Medicine [DOI: 10.1038/s41591-024-03085-5], was done in collaboration with colleagues at the University of Bristol, UK; KU Leuven, Belgium; and the NIHR BioResource, currently based at the University of Cambridge, UK. The findings will improve clinical diagnostic services for patients with neurodevelopmental disorders.
Sleep medicine experts available for interview on breaking and trending news about obstructive sleep apnea, CPAP, and more
Susan Chipman, a pioneer in the field of cognitive science, has pledged a $1 million planned gift to the University of California San Diego's Department of Cognitive Science. The Susan E.F. Chipman and Robert G. Fitzgerald Graduate Fellowship Fund in Cognitive Science is the first of its kind in the UC San Diego department, which was the world's first department established in cognitive science.
For patients with chronic migraine, nerve decompression surgery effectively reduces the number of headache days – the outcome measure preferred by neurologists – along with other measures including the frequency and intensity of migraine attacks, reports a study in the June issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
During pregnancy, the effects of therapeutical doses of amphetamine have been investigated on birth outcomes in humans. However, a thorough investigation of the mechanisms underlying the long-term effects of embryonal exposure to addictive doses of amphetamine remains largely unexplored.
A novel speech analysis tool that uses artificial intelligence successfully detected mild cognitive impairment and dementia in a Spanish-speaking population, according to research led by UT Southwestern Medical Center. The study, published in Frontiers in Neurology, provides preliminary support for the algorithm as an early screening tool that may help identify patients at risk of developing dementia.
Brain cancer is difficult to treat when it starts growing, and a prevalent type, known as a glioma, has a poor five-year survival rate.
While older drugs for epilepsy, taken while pregnant, have been shown in previous research to affect the creative thinking of children, a new study finds no effects on creativity for children born to those taking newer epilepsy drugs. This study is published in the May 29, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Endocrinologists from Cedars-Sinai will present research findings and discuss advances in clinical care throughout ENDO 2024, the Endocrine Society’s annual meeting in Boston, June 1-4.
You might never know they’re there. But brain aneurysms can turn into ticking time bombs medical science is still attempting to understand. A Penn State Health expert discusses the unsure world of cerebral aneurysms.
The 149th Annual Meeting of the American Neurological Association (ANA) will explore new frontiers in neurology, including the significant progress made in our understanding of the major mutations causing ALS, recent advances in artificial intelligence (AI) that help us better understand the causes, prognosis, and treatment of neurological disease, and new information about encephalitis, a rare and devastating neurologic disease.
A new study by UC Davis researchers finds key differences in the development of the cortex between autistic boys and girls ages 2-13.
A groundbreaking study led by UCLA Health has unveiled the most detailed view of the complex biological mechanisms underlying autism, showing the first link between genetic risk of the disorder to observed cellular and genetic activity across different layers of the brain.
Using new sequencing technologies, UCLA and University of Pennsylvania researchers uncovered 214,516 unique isoforms in the developing neocortex — over 70% of which have not been previously studied.
Volume 29, Issue 2 of SLAS Discovery features two review articles, six original research articles covering phenotypic screening perspectives, medulloblastoma therapies and interventions for neurodegenerative diseases.
Announcement of next JNSPG Editor in Chief
Even slight cognitive changes can affect an older person’s decision to stop driving, according to a new study by researchers at Washington University School of Medicine in St. Louis. The findings suggest that routine cognitive testing — in particular, the kind of screening designed to pick up the earliest, most subtle decline — could help older adults and their physicians make decisions about driving that maximizes safety while preserving independence as long as possible.
What factors lead older adults to stop driving? A new study followed older adults who had no memory or thinking problems to examine this question. The study is published in the May 22, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
People who eat more ultra-processed foods like soft drinks, chips and cookies may have a higher risk of having memory and thinking problems and having a stroke than those who eat fewer processed foods, according to a new study published in the May 22, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that eating ultra-processed foods causes memory and thinking problems and stroke. It only shows an association.
A study co-led by researchers at UCLA Health has found distinct brain connectivity patterns in six-week-old infants at risk for developing autism spectrum disorder (ASD).
Engineers at the University of California San Diego have developed a wearable ultrasound patch that can offer continuous, non-invasive monitoring of blood flow in the brain. The soft and stretchy patch can be comfortably worn on the temple to provide three-dimensional data on cerebral blood flow—a first in wearable technology.
Scientists have long been studying the brain with a goal of aiding healthier aging. While much is known about risk factors for accelerated brain aging, less has been uncovered to identify ways to reduce cognitive decline.
Lucy, with her boundless puppy-like energy even at 12 years old, is more than just a pet to Susan Ketcham. She's now part of a research project that could transform the way we treat brain cancer – in both dogs and humans. This study at Virginia Tech's Virginia-Maryland College of Veterinary Medicine explores an innovative therapy called histotripsy.
An increase in nightmares and hallucinations could signal the onset of autoimmune diseases such as lupus, according to a new study.
Current methods to model or correct mutations in live cells are inefficient, especially when multiplexing — installing multiple point mutations simultaneously across the genome. Researchers from the UC San Diego have developed new, efficient genome editing tools called multiplexed orthogonal base editors (MOBEs) to install multiple point mutations at once.
MIRA Pharmaceuticals, Inc. (NASDAQ: MIRA) ("MIRA" or the "Company"), a pre-clinical-stage pharmaceutical company focused on the treatment of neurologic and neuropsychiatric disorders, announced it is in advanced discussions with Memorial Sloan Kettering Cancer Center (MSK) to initiate a preclinical study evaluating MIRA's novel oral ketamine analog, Ketamir-2, for the treatment of cancer-related pain and depression.
Australian scientists are exploring how harmful gut bacteria from a poor diet can access the brain and trigger early onset Alzheimer's disease.
Dr. Cook realized, when his father was diagnosed with epilepsy, that a system to identify and predict seizures could improve care and change people's lives. In this episode, Dr. Cook talks about entrepreneurship in epilepsy and advancing the field through innovation.
MIRA Pharmaceuticals, Inc. (NASDAQ: MIRA) ("MIRA" or the "Company"), a pre-clinical-stage pharmaceutical company focused on the treatment of neurologic and neuropsychiatric disorders, announced that it has advanced new preclinical studies using Ketamir-2, its differentiated oral ketamine analog, towards clinical development for the treatment of severe post-traumatic stress disorder (PTSD) and other leading mental health disorders and neuropathic pain indications.
May is both Brain Tumor Awareness Month and National Cancer Research Month. Virginia Tech’s Fralin Biomedical Research Institute at VTC is dedicated to advancing health through a better understanding of cancer and brain tumors and developing new ways to treat and prevent them.
Researchers at the UNC School of Medicine, UCSF, Stanford, and Harvard determined that a protein prediction technology can yield accurate results in the hunt to efficiently find the best possible drug candidates for many conditions.
Learning a simple acronym could help you save a life. A Penn State Health expert explains why “time is brain.”
A new guideline has been issued to help neurologists and other clinicians determine the best antiseizure medications for people with epilepsy who may become pregnant.
Hackensack Meridian Jersey Shore University Medical Center celebrates a significant milestone: the attainment of Global Healthcare Accreditation (GHA) for Medical Travel Services for its Center for Treatment of Paralysis and Reconstructive Nerve Surgery. The Center is the first GHA accredited facility in New Jersey.
A new study led by UCLA Health has shown that repetitive practice not only is helpful in improving skills but also leads to profound changes in the brain’s memory pathways.
Nasal chemosensation is considered the evolutionarily oldest mammalian sense and, together with somatosensation, is crucial for neonatal well-being before auditory and visual pathways start engaging the brain.
New research led by Children’s Hospital Los Angeles has found that racial and socioeconomic disparities contribute to delayed care for craniosynostosis—a rare birth defect that occurs when a baby’s skull bones close too early.In the study, being Black/African American, having public insurance and living in an economically disadvantaged area were all risk factors for presenting for a first consultation at older ages.
Restoring motor control and sensation from an artificial hand in a natural way remains a scientific “holy grail.” Researchers have developed a novel biohybrid neuro-prosthetic research platform comprised of a dexterous artificial hand electrically interfaced with biological neural networks. Ultimately, this could lead to a better understanding of the complex sensation of touch, which is necessary for refined control of the hand.
Results from an Iowa State University pilot study indicate three months of exercise benefits vascular health, but improving brain blood flow may require more time.
A research team led by the University of California, Irvine has revealed the link between the frequency of sleep apnea events during the rapid-eye-movement stage and the severity of verbal memory impairment in older adults at risk for Alzheimer’s disease. Verbal memory refers to the cognitive ability to retain and recall information presented through spoken words or written text and is particularly vulnerable to Alzheimer’s.
Engineers at the University of California San Diego have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer’s disease. Additionally, researchers observed sex-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of “old” oligodendrocytes to “old” neurons compared to the male cortex.
Xylazine, often found in street-drug combo with fentanyl, was thought to only bind to the α2-adrenergic receptor, but UNC-Chapel Hill scientists discovered it also binds to opioid receptors, which could have profound impacts on fentanyl overdose treatment.
Researchers at the Icahn School of Medicine at Mount Sinai have made a significant discovery, identifying genetic connections between inflammatory bowel disease (IBD) and Parkinson’s disease (PD). Published in Genome Medicine on May 13, their study highlights the potential for joint therapeutic strategies to target these two challenging disorders.
A night spent dreaming can help you forget the mundane and better process the extreme, according to a new University of California, Irvine study. Novel work by researchers in the UC Irvine Sleep and Cognition Lab examined how dream recall and mood affected next-day memory consolidation and emotion regulation.
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