Using a combination of computational modeling and experimental techniques, a research team has developed new information about how intercellular communication affects the differentiation of an embryonic stem cell colony over time.
Research from the Penn Medicine Center for Digital Health and the World Well-Being Project marries social media data with medical-outcomes data for the first time.
Early results from a first-of-its-kind study by researchers from the Institute for Reproductive Health at Georgetown University Medical Center suggests that typical use of a certain family planning app is as effective as other modern methods for avoiding an unplanned pregnancy.
People who undergo Roux-en-Y gastric bypass surgery, a common type of bariatric surgery, are at an increased risk for alcohol-related problems. However, common screening tools that help physicians identify patients at high risk for alcohol use disorder fail to work well in this population.
A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process — changes in mammary glands to accommodate breastfeeding — uses a molecular process believed to contribute to survival of pre-malignant breast cells.
A team of researchers at the University of Chicago has received a $3.4 million grant from the National Institutes of Health. The funding will help the team develop robotic arms patients can control with their minds that receive sensory feedback from attached prosthetic hands.
Children who experience less parental warmth and more harshness in their home environments may be more aggressive and lack empathy and a moral compass, according to a study by researchers at Michigan State University, the University of Pennsylvania and the University of Michigan. The study is published in the Journal of the American Academy of Child and Adolescent Psychiatry.
Biologists at Johns Hopkins University grew human retinas from scratch to determine how cells that allow people to see in color are made.
Researchers from three Milwaukee-area universities have developed a “stripped-down” estrogen molecule that improves memory in an animal model of post-menopausal dementia, kickstarting new drug discovery for treating memory loss in women.
or adults over age 65, surgical complications can dampen not only their physical health but also their mental sharpness, with more than half of high-risk cases declining into delirium. In new Duke University research, scientists show in a mouse model that a current treatment for seizures can also reverse brain inflammation, such as inflammation after surgery, and the subsequent confusion or cognitive decline that results.
Researchers from Missouri S&T and three private companies will combine their expertise to create charging stations for electric vehicles that could charge a car in less than 10 minutes – matching the time it takes to fill up a conventional vehicle with gasoline.“The big problem with electric vehicles is range, and it’s not so much range as range anxiety.
Two studies into deadly cancers in dogs are now underway, offered through the newly formed Clinical Trials Office at Cummings Veterinary Medical Center at Tufts University. Dogs with spontaneous osteosarcoma, as well as dogs with mast cell tumors and solid tumors, may be eligible for enrollment.
In one of the largest clinical studies to ever examine the impact of using a blood test to detect treatable mutations in non-small cell lung cancer (NSCLC), researchers from the Abramson Cancer Center of the University of Pennsylvania found that they could identify significantly more mutations through liquid biopsy instead of a solid tissue biopsy alone. The findings also show that patients whose actionable mutations were detected by the blood based liquid biopsy responded favorably to targeted therapies.
The Ketogenic Diet, simple caloric restriction, or the pharmaceutical rapamycin appear to improve neurovascular function and prevent cognitive decline in animal models
Pediatric researchers have discovered common gene variants associated with migraines in African-American children. The research adds to knowledge of genetic influences on childhood migraine and may lead to future precision medicine treatments for African-American children with these intense headaches.
Eruption patterns in a New Zealand volcanic system reveal how the movement of magma rising through the crust leads to smaller, more frequent eruptions.
In studies of mouse cells, Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar.
Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for a therapeutic action of an ancient herbal medicine used across Africa to treat various illnesses, including epilepsy.
West Virginia University’s School of Pharmacy will soon become one of the few pharmacy schools in the nation that leads a center of biomedical research excellence.
Using a statistical technique called network meta-analysis, researchers have combined the results of dozens of studies of dietary oils to identify those with the best effect on patients' LDL cholesterol and other blood lipids.
A bacterium known for causing stomach cancer might also increase the risk of certain colorectal cancers, particularly among African Americans, according to a study led by Duke Cancer Institute researchers.
Pediatric researchers studying the life-threatening blood disorder Fanconi anemia have devised a method to block the abnormal biological signals that drive the disease. This proof-of-concept finding in animals and stem cells may lay the foundation for better treatments for children with the rare, frequently fatal disease.
Washington University School of Medicine in St. Louis led a national study of 2,400 first-time pregnant women. The research showed that the timing of pushing has no effect on whether women deliver vaginally or by C-section.
A team of clinicians, dietitians and researchers has created an automated program to screen for malnutrition in hospitalized children, providing daily alerts to healthcare providers so they can quickly intervene with appropriate treatment. The malnutrition screen draws on existing patient data in electronic health records (EHR).
Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually develop drug resistance, leaving doctors desperate for alternatives. Now, researchers from Case Western Reserve University School of Medicine have uncovered a previously uncharacterized, bridge-like structure within the human estrogen receptor that could serve as a valuable new drug target. In Nature Communications, researchers describe a “burning the bridge” strategy to disrupting the estrogen receptor, and how to screen breast cancer drugs designed to do it.
An inability to properly use the essential mineral manganese could be to blame for some cases of severe scoliosis, according to a new study from Washington University School of Medicine in St. Louis.
Gone are the days of heavy science textbooks with over-used examples and hard-to-grasp lessons. The Genetic Science Learning Center (GSLC) at the University of Utah is bringing science education into the 21st century with an online, interactive and multimedia curriculum that teaches up-to-date concepts in evolution and genetics to high school students.
Northwestern University and Washington University School of Medicine researchers have developed the first example of a bioelectronic medicine: an implantable, biodegradable wireless device that speeds nerve regeneration and improves healing of a damaged nerve. Their device delivered pulses of electricity to damaged nerves in rats after a surgical repair process, accelerating the regrowth of nerves and enhancing the recovery of muscle strength and control. The device is the size of a dime and the thickness of a sheet of paper.
A culturally tailored program used when discharging stroke patients from the hospital helped to lower blood pressure among Hispanic individuals one year later, finds a new study led by researchers at NYU College of Global Public Health.
For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth. The research offers proof-of-concept for prenatal use of a sophisticated, low-toxicity tool that efficiently edits DNA building blocks in disease-causing genes.
For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth.
A new method for sequencing the chemical groups attached to the surface of DNA is paving the way for better detection of cancer and other diseases in the blood.
Peripheral nerve injuries leave people with tingling, numbness and weakness in their arms, hands and legs. Researchers at Washington University School of Medicine in St. Louis and Northwestern have developed an implantable, bioabsorbable device that speeds recovery in rats by stimulating injured nerves with electricity.
Two decades ago, Clifford B. Saper, MD/PhD, Chairman of the Department of Neurology at Beth Israel Deaconess Medical Center, and colleagues discovered a set of nerve cells they thought might be the switch that turns the brain off, allowing it to sleep. In a new study, Saper and colleagues demonstrate in mice that that these cells – located in a region of the hypothalamus called the ventrolateral preoptic nucleus – are in fact essential to normal sleep.
Genetic testing for newly diagnosed breast cancer patients can help guide treatment and identify whether family members are at increased risk, but many patients aren't aware of these benefits. A new study shows that decision support tools used in tandem with genetic counselors can help patients understand.
Lab-on-a-chip devices harness electrical signals to measure glucose, tell apart blood type and detect viruses or cancer. But biological samples need hafnium oxide for protection from the electric fields.
Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease. In animal hearts, the researchers identified an array of cell types and investigated the “transcriptional landscape” in rich detail.
Study findings sourced by the National Cancer Database published in Annals of Surgery also do not show that more frequent surveillance improved survival following lung cancer recurrence.
The National Institute of Dental and Craniofacial Research and National Institute on Aging have awarded the NYU Rory Meyers College of Nursing with funding to improve the oral hygiene of people with mild dementia. The $3.47 million, five-year grant will be used to implement and study a unique oral health intervention involving family caregivers in New York and North Carolina.
Scientists at Scripps Research have discovered the role of an immune system double agent. This molecule, called USP18, can help curtail immune responses, but it can also open the door to bacterial infections, such as harmful listeria and staph infections.
In research that extends knowledge about the physiology of regeneration and wound repair, Tufts University biologists have discovered that amputation of one limb is immediately reflected in the bioelectric properties of the contralateral, or opposing, un-damaged limb of developing frogs.
A twist on the molecular mechanism of how a new cancer drug works could aid in better identifying the best treatments for patients for an array of cancers. The team identified over 500 sites in DNA that require an enzyme called ATR checkpoint kinase to not break when they are replicated.
For children born with Saul-Wilson syndrome, and their parents, much of their lives are spent searching for answers. First defined in 1990, only 14 cases are known worldwide. Today, these individuals have answers. A study published today in the American Journal of Human Genetics, has uncovered the cause of Saul-Wilson syndrome.
Some people suffer unpredictable bouts of abdominal pain and constipation. A new study in mice, from Washington University School of Medicine in St. Louis, shows that viruses that target the nervous system can kill neurons in the gut that coordinate the process of moving waste along. Such viruses may be involved in causing people's digestive woes.
A UNC Lineberger Comprehensive Cancer Center researcher and his colleagues have been awarded a five-year, $3.2 million grant from the National Cancer Institute to investigate how to improve radiation treatment for dogs undergoing treatment for sarcoma.
Engineers from the University of Utah’s School of Computing conducted a study to determine if homeowners change the way they live if they could visualize the air quality in their house. They provide homeowners pollution sensors and a tablet to see the air quality data in their homes.
A chemotherapy drug commonly used to treat breast cancer alters brain structure and function in mice that express the human APOE4 gene, known to significantly increase risk of developing Alzheimer’s disease, according to a study led by Georgetown investigators.
The first large U.S. study of cognition in older breast cancer patients found that within the first two years after diagnosis and treatment, most women do not experience cancer-related cognitive problems.
Ann Morris, associate professor of biology at UK, will use the National Institutes of Health funding to continue her cutting-edge research in retinal development and regeneration.
Communicating flood risk can be more streamlined and an interdisciplinary team of engineers, hydrologists, and computer scientists plan to develop apps to improve monitoring and predictions.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right