Curated News: JAMA

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4-Sep-2020 2:05 PM EDT
Some Children at Higher Risk of Privacy Violations from Digital Apps
Michigan Medicine - University of Michigan

While federal privacy laws prohibit digital platforms from storing and sharing children’s personal information, those rules aren’t always enforced, researchers find.

Released: 3-Sep-2020 12:50 PM EDT
COVID has likely tripled depression rate: BU study
Boston University School of Medicine

A first-of-its-kind study from the Boston University School of Public Health (BUSPH) finds 27.8% of U.S. adults had depression symptoms as of mid-April, compared to 8.5% before the COVID-19 pandemic.

3-Sep-2020 7:05 AM EDT
Study: Vitamin D deficiency may raise risk of getting COVID-19
University of Chicago Medical Center

In a retrospective study of patients tested for COVID-19, researchers at the University of Chicago Medicine found an association between vitamin D deficiency and the likelihood of becoming infected with the coronavirus. The findings were published Sept. 3 in JAMA Network Open.

Released: 2-Sep-2020 5:55 PM EDT
Steroid found to improve survival of critically ill COVID-19 patients
Imperial College London

A new international study published today [02 September] has shown that treating critically ill patients with COVID-19 with the steroid hydrocortisone improves their chances of recovery.

Released: 1-Sep-2020 6:35 PM EDT
Study: Anonymized cell phone location data can help monitor COVID-19 growth rates
Mount Auburn Hospital

In March 2020, federal officials declared the COVID-19 outbreak a national emergency. Around the same time, most states implemented stay-at-home advisories - to different degrees and at different times.

   
Released: 1-Sep-2020 6:10 PM EDT
Improving FDA's COVID-19 vaccine authorization and approval process
Dartmouth College

On March 28, the Food and Drug Administration (FDA) exercised its Emergency Use Authorization (EUA) authority to allow the use of hydroxychloroquine for the treatment of COVID-19.

Released: 1-Sep-2020 11:30 AM EDT
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.

Released: 31-Aug-2020 12:30 PM EDT
College students access eating disorders therapy via phone app
Washington University in St. Louis

Studying college women with eating disorders, a team led by researchers at Washington University School of Medicine in St. Louis found that a phone-based app that delivers a form of cognitive behavioral therapy was an effective means of intervention in addressing specific disorders.

27-Aug-2020 3:55 PM EDT
Cell Phone Location Used to Estimate COVID-19 Growth Rates
Perelman School of Medicine at the University of Pennsylvania

Data shows that coronavirus infection rates were lower in counties where cell phone activity declined at workplaces and increased at home

   
26-Aug-2020 12:45 PM EDT
Cochlear implants should be recommended for adults more often
Washington University in St. Louis

An international group of hearing specialists has released a new set of recommendations emphasizing that cochlear implants should be offered to adults who have moderate to severe or worse hearing loss much more often than is the current practice. The group hopes the recommendations help increase usage of such devices, potentially improving hearing and quality of life for millions worldwide.

25-Aug-2020 1:00 PM EDT
Systematic Testing of Environmental Surfaces in a Radiation Oncology Clinic Shows no Detectable SARS-CoV2
Rutgers Cancer Institute

It has been hypothesized that SARS-CoV2 spread among people via droplets that come from the nose and mouth or through contact with contaminated objects and surfaces. Researchers at Rutgers Cancer Institute found that environmental surface testing at the center’s Radiation Oncology Department located within Robert Wood Johnson University Hospital, an RWJBarnabas Health facility, during the height of the COVID-19 pandemic in the state showed no detectable SARS-CoV2 – the virus that causes COVID-19.

Released: 26-Aug-2020 1:20 PM EDT
Gunshot Injuries in California Drop, but Percentage of Firearm Deaths Goes Up
UC Davis Health (Defunct)

Despite a significant drop in gun injuries, California has experienced a substantial increase in the state’s overall death rate among those wounded by firearms.

25-Aug-2020 11:00 AM EDT
International cardiology trial shows potential benefit of using personalized medicine in blood thinner therapy selection
University Health Network (UHN)

An international, first-of-its-kind cardiology trial used personalized genetic testing to reduce by 34 per cent the number of serious adverse events following balloon angioplasty, a treatment for the most common form of heart disease.

24-Aug-2020 4:05 PM EDT
Largest pharmacogenetic clinical trial in cardiology shows potential benefit in individualized approach to anti-platelet therapy
Mayo Clinic

ROCHESTER, Minn. ― Heart patients who undergo percutaneous coronary intervention (PCI) or stent placement― nonsurgical procedures to improve blood flow to the heart ― are typically prescribed anti-platelet therapy to avoid blood clots that can lead to a heart attack or stroke. New research from the international TAILOR-PCI trial, the largest pharmacogenetics clinical trial in cardiology, suggests that genetic testing could potentially be a useful tool to help select antiplatelet medication. Pharmacogenetics is the use of a patient's genetic makeup in prescribing treatments that are likely to be most successful.

20-Aug-2020 6:30 PM EDT
Compared to Placebo, Vitamin D Has No Benefit for Severe Asthma Attacks
Health Sciences at the University of Pittsburgh

Contrary to earlier observational results, vitamin D supplements do not prevent severe asthma attacks in at-risk children, according to the first placebo-controlled clinical trial to test this relationship.

Released: 24-Aug-2020 5:05 PM EDT
New Study Suggests Role for Hormone Therapy to Treat Even Small, T1a Breast Cancers
Roswell Park Comprehensive Cancer Center

Many people diagnosed with breast cancers that are small but invasive could benefit from hormone treatment, a new study led by physicians at Roswell Park Comprehensive Cancer Center confirms. Their findings were published today in the journal JAMA Network Open.

Released: 21-Aug-2020 4:20 PM EDT
Effect of remdesivir vs standard care on clinical status of patients with moderate COVID-19
JAMA - Journal of the American Medical Association

This open-label randomized trial compares the effect of remdesivir (5 or 10 days) compared with standard care on clinical status 11 days after treatment initiation among patients with confirmed SARS-CoV-2 infection hospitalized with moderate pneumonia.

18-Aug-2020 10:05 PM EDT
Robotic Surgery May Improve Outcomes in Mouth and Throat Cancer
Cedars-Sinai

Robotic surgery for patients with early stage, oropharyngeal squamous cell cancer is associated with improved health outcomes, including better long-term survival, according to a Cedars-Sinai study published Thursday in JAMA Oncology. Oropharyngeal cancer occurs in the back of the throat and includes the base of the tongue and tonsils.

Released: 19-Aug-2020 4:20 PM EDT
Is COVID-19 Transmitted Through Breast Milk? Study Suggests Not Likely
UC San Diego Health

A recent study by researchers at University of California San Diego School of Medicine suggests transmission of COVID-19 through breast milk is not likely. The infectious virus was not detected in 64 samples of breast milk tested.

Released: 18-Aug-2020 2:05 PM EDT
People with diabetes, depression improve with TLC
University of Washington School of Medicine

When it comes to improving care, patients really thrive with a little TLC. Researchers from Emory University, University of Washington School of Medicine, and their colleagues in India compared a collaborative care model with usual care in 404 patients with diabetes and moderate-to-severe depressive symptoms. More than 70 percent in the group receiving the integrated approach had improvements in diabetes and depression. The key to the model is creating patient-care managers who coordinate care with doctors, nurses and family members. The patients thrive with this kind of attention.

14-Aug-2020 8:50 AM EDT
These drugs carry risks & may not help, but many dementia patients get them anyway, study finds
Michigan Medicine - University of Michigan

Nearly three-quarters of older adults with dementia have filled prescriptions for medicines that act on their brain and nervous system, but aren’t designed for dementia, a new study shows. That’s despite the special risks that such drugs carry for older adults -- and the lack of evidence that they actually ease dementia-related behavior problems.

13-Aug-2020 12:30 PM EDT
Experts Question Need to Wait Days Between Introducing New Solid Foods to Infants
Ann and Robert H. Lurie Children's Hospital of Chicago

The current recommendations from the American Academy of Pediatrics (AAP) and the Centers for Disease Control and Prevention (CDC) call for introducing to infants one single-ingredient food at a time and waiting three to five days to observe for food allergy before introducing another new food. However, the long waiting period might be too long, given that food allergy becomes apparent within minutes to a few hours after eating a new food. A recent survey of pediatricians, published in JAMA Network Open, found significant variability in their recommendations to parents about solid food introduction, which calls into question the relevance of the current guidelines.

13-Aug-2020 10:25 AM EDT
Patients’ Access to Opioid Treatment Cumbersome
Vanderbilt University Medical Center

The “secret shopper” study used trained actors attempting to get into treatment with an addiction provider in 10 U.S. states. The results, with more than 10,000 unique patients, revealed numerous challenges in scheduling a first-time appointment to receive medications for opioid use disorder, including finding a provider who takes insurance rather than cash.

Released: 14-Aug-2020 8:45 AM EDT
Many medical “rainy day” accounts aren’t getting opened or filled, study finds
Michigan Medicine - University of Michigan

One-third of the people who could benefit from a special type of savings account to cushion the blow of their health plan deductible aren’t doing so, according to a new study. And even among people who do open a health savings account (HSA), half haven’t put any money into it in the past year.

Released: 12-Aug-2020 12:10 PM EDT
Some physicians are ordering thyroid tests for unsupported reasons
Michigan Medicine - University of Michigan

Up to one-third of physicians reported sending patients for a thyroid ultrasound for reasons not supported by clinical care guidelines, a new study led by University of Michigan Rogel Cancer Center researchers finds. Routine use of ultrasounds to detect cancerous thyroid nodules have led to a significant increase in thyroid cancer cases in recent years, although many are low-risk and unlikely to cause serious harm.

11-Aug-2020 5:00 PM EDT
Yoga Shown to Improve Anxiety, Study Shows
NYU Langone Health

A new study led by researchers at NYU Langone Health found that yoga improves symptoms of generalized anxiety disorder.

Released: 11-Aug-2020 2:00 PM EDT
NAU professors examine the role racial disparities play in mortality rates of rural, urban residents
Northern Arizona University

In a first-of-its-kind study, researchers collected nationally representative data from 3,131 U.S. counties between 1968-2016, and looked at historical trends in death rates between older black and white adults living in different communities.

11-Aug-2020 9:00 AM EDT
Researchers Create Mask Filtration Effectiveness Hierarchy
University of North Carolina School of Medicine

Infection prevention experts at the UNC Medical Center set out to gather evidence on the fitted filtration efficiency of dozens of different types of masks and mask modifications, including masks sterilized for reuse, expired masks, novel masks sourced from domestic and overseas sources, and homemade masks.

Released: 10-Aug-2020 4:05 PM EDT
Young adults' risks from first-time opioid prescriptions may not be as high as previously thought
Indiana University

Young adults and adolescents who are prescribed opioids for the first time may be at a slightly greater risk of developing a substance-related problem later in life, according to a new study co-authored by Indiana University researchers. However, the risk may not be as high as previously thought.

5-Aug-2020 12:40 PM EDT
Cancer vs. COVID: When a pandemic upended cancer care
Michigan Medicine - University of Michigan

A team of researchers interviewed physicians and patients at the beginning of the COVID-19 pandemic to identify eight scenarios impacting cancer care. Using communication strategies, they created examples of language to help oncologists respond to patients empathetically.

Released: 6-Aug-2020 8:10 AM EDT
Recovery After Severe COVID Infection Poses Unique Challenges
Michigan Medicine - University of Michigan

As more patients recovered from COVID-19 are discharged from stressed ICUs, they face multiple problems brought on by the pandemic.

31-Jul-2020 4:05 PM EDT
The effects of COVID-19 on emergency visits, hospitalizations
Mayo Clinic

COVID-19 swept into the U.S., hospitals across the country have reported that their emergency departments are emptying out. In a new study published Monday, Aug. 3, in JAMA Internal Medicine, a team of researchers from multiple institutions provides insights into this phenomenon.

Released: 31-Jul-2020 3:50 PM EDT
SARS-CoV-2 screening strategies for safe reopening of college campuses
JAMA - Journal of the American Medical Association

What The Study Did: This study defines the screening performance standards for SARS-CoV-2 tests that would permit the safe return of students to U.S. residential college campuses this fall. Authors: A. David Paltiel, Ph.D., of the Yale School of Public Health in New Haven, Connecticut, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2020.16818) Editor's Note: The article includes funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. ### Media advisory: The full study and commentary are linked to this news release. Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/1

   
Released: 31-Jul-2020 3:35 PM EDT
Targetable biological mechanisms implicated in emergent psychiatric conditions associated with SARS-CoV-2
JAMA - Journal of the American Medical Association

Targetable biological mechanisms implicated in emergent psychiatric conditions associated with SARS-CoV-2 infection are discussed in this Viewpoint.

Released: 30-Jul-2020 1:10 PM EDT
BIDMC’s Research & Health News Digest – July 2020 Edition
Beth Israel Lahey Health

The July 2020 Edition of Beth Israel Deaconess Medical Center’s (BIDMC) Research & Health News Digest.

28-Jul-2020 4:15 PM EDT
Hearing loss linked to neurocognitive deficits in childhood cancer survivors
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital are studying how hearing loss can affect the neurocognitive abilities of childhood cancer survivors. Findings show that survivors with severe hearing loss are at a significant increased risk for neurocognitive deficits, independent of what type of therapy they receive.

27-Jul-2020 12:05 PM EDT
Young Kids Could Spread COVID-19 As Much As Older Children and Adults
Ann and Robert H. Lurie Children's Hospital of Chicago

A study from Ann & Robert H. Lurie Children’s Hospital of Chicago discovered that children younger than 5 years with mild to moderate COVID-19 have much higher levels of genetic material for the virus in the nose compared to older children and adults. Findings, published in JAMA Pediatrics, point to the possibility that the youngest children transmit the virus as much as other age groups. The ability of younger children to spread COVID-19 may have been under-recognized given the rapid and sustained closure of schools and daycare during the pandemic.

Released: 29-Jul-2020 1:10 PM EDT
Researchers Outline Need for Further Evaluation of Gene Expression Profiling in Melanoma Patients
Huntsman Cancer Institute at the University of Utah

A consensus statement published today in JAMA Dermatology by a group of melanoma researchers evaluates the use of prognostic genetic expression profiling within clinical treatment of patients with melanoma. The group cautioned against routine use of currently-available genetic expression profiling tests for patients with cutaneous melanoma.

Released: 28-Jul-2020 4:55 PM EDT
New blood test shows great promise in the diagnosis of Alzheimer's disease
Lund University

A new blood test demonstrated remarkable promise in discriminating between persons with and without Alzheimer's disease and in persons at known genetic risk may be able to detect the disease as early as 20 years before the onset of cognitive impairment, according to a large international study published today in the Journal of the American Medical Association (JAMA) and simultaneously presented at the Alzheimer's Association International Conference.

Released: 28-Jul-2020 3:45 PM EDT
Quitline plus surgery are big motivators for giving up smoking
UC Davis Health (Defunct)

Smokers who have thoracic surgery are much more likely to stop using tobacco if they also complete a quitline intervention, a new UC Davis Health study shows.

Released: 28-Jul-2020 12:30 PM EDT
Story Tips From Johns Hopkins Experts on COVID-19
Johns Hopkins Medicine

It seems there will never be enough “thank-yous” for the incredible doctors, nurses, technicians and support staff members who are working around the clock to help patients who have COVID-19, the dangerous coronavirus disease. Their dedication, determination and spirit enable Johns Hopkins to deliver the promise of medicine. As the mother of a 2-year-old, with responsibilities that sometimes require escorting COVID-19 patients at Sibley Memorial Hospital, Safety and Security Officer, SPO, Lolita Moore says she takes the necessary steps to protect herself and her family against the virus and prays daily. “I like that I can still be out helping people during the pandemic,” she says.

27-Jul-2020 3:40 PM EDT
New Study Finds Racial Disparities in COVID-19-related Deaths Exist Beyond Income Differences in 10 Large U.S. Cities
NYU Langone Health

New analyses by a team of researchers at NYU Grossman School of Medicine examine the interplay between race/ethnicity and income on COVID-19 cases and related deaths in 10 major U.S. cities. The researchers found that non-white counties had higher cumulative incidences and deaths compared to predominantly white counties—and this was true for both low-income and high-income communities.

Released: 27-Jul-2020 2:55 PM EDT
Maternal depression increases odds of depression in offspring, study shows
University of Texas Health Science Center at Houston

Depression in mothers during and after pregnancy increased the odds of depression in offspring during adolescence and adulthood by 70%, according to a new study by researchers at UTHealth.

23-Jul-2020 4:00 PM EDT
Insulin Cost-Sharing Caps May Help Kids, Young Adults With Type 1 Diabetes
Michigan Medicine - University of Michigan

Although additional policies are needed to relieve insulin’s financial burden, researchers find a national cost-sharing cap helps privately insured children and young adults with type 1 diabetes pay less out-of-pocket.

Released: 23-Jul-2020 12:10 PM EDT
A conversation game may reduce disparity in end-of-life care for African Americans
Penn State College of Medicine

A Penn State College of Medicine research team found that playing a simple conversation game may encourage African Americans to make plans for their end-of-life care.

Released: 23-Jul-2020 11:00 AM EDT
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.

16-Jul-2020 4:25 PM EDT
How should hospitals ask patients for donations?
Michigan Medicine - University of Michigan

A new study looks for the first time at patients’ views of hospital fundraising, including legally allowable practices that encourage physicians to work with their hospital’s fundraising professionals.

Released: 17-Jul-2020 12:40 PM EDT
Cannabis shows potential for mitigating sickle cell disease pain
University of California, Irvine

Cannabis appears to be a safe and potentially effective treatment for the chronic pain that afflicts people with sickle cell disease, according to a new clinical trial co-led by University of California, Irvine researcher Kalpna Gupta and Dr. Donald Abrams of UC San Francisco. The findings appear in JAMA Network Open.



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